The document discusses Lawrence F. Andrews' preadjusted edgewise appliance, which aims to achieve optimal occlusion by identifying six keys: interarch relationship, crown angulation, crown inclination, rotations, tight contacts, and occlusal plane. Andrews compared 120 non-orthodontic models with 1150 treated cases, highlighting significant inadequacies in post-treatment models based on his criteria. The findings led to the development of a fully programmed appliance that addresses the shortcomings of traditional edgewise appliances, emphasizing the importance of proper bracket design and minimized wire bending for optimal treatment outcomes.