This document describes a method for analyzing cardiac MRI images to identify scar tissue from a previous heart attack and assess the risk of future cardiac arrhythmias. Analysis of the scar tissue location and extent seen on MRI images can indicate the likelihood of arrhythmias occurring and help determine whether a patient should receive an implantable cardiac defibrillator. The technology provides improved risk stratification by predicting arrhythmia risk based on MRI findings, which could help guide decisions about costly defibrillator implants.

1. METHOD OF ANALYSIS OF CARDIAC IMAGES
Keywords: Magnetic Resonance Imaging, heart infarct, intracardiac defibrillator, cardiac arrhythmia
Background
The invention relates to a method of analysis of cardiac images, in particular magnetic
resonance (MR) images. Magnetic resonance images of the heart of a patient who has had a
myocardial infarction can enable the muscle regions with reduced blood flow, the scar tissue,
to be identified and its location and extent to be mapped and determined. This is particularly
facilitated if an MR imaging contrast agent is injected or infused into the patient’s
cardiovascular system. Patients who have suffered but survived one heart attack may
subsequently suffer a possibly disabling or fatal cardiac arrhythmia. In many cases, the patient
will be fitted with an Intracardiac Defibrillator (ICD), which has high implantation and follow
up costs.
Description
Analysis of MR images of cardiac scar tissue may
yield a result which can indicate the likelihood of a
serious cardiac arrhythmia occurring in the near
future and which accordingly may be used as one
factor in deciding whether or not an Intracardiac
Defibrillator (ICD) should be implanted promptly.
The surgery involved is extensive and has a risk
factor (ejection fraction - LVEF), the guidelines for
ICD implantation are controversial. There is a
current need for an improved method of risk
stratification and our technology provides the risk
stratification and predicting the likelihood of
occurrence of cardiac arrhythmia.
Figure MRI Image of the myocardium
Applications and benefits
- Method of image analysis of a cardiac image
- Cardiac arrhythmia prediction matrix (within 10 weeks of myocardial infarction)
Status
- Validated image analysis
- Clinical trials
IPR
Patent pending
We are seeking R&D and licensing partners.