The presentation aims to give a basic understanding about the various drug reactions. It explains the mechanisms of ADR, Types, predisposing factors for ADR, and other common drug related adverse events
The presentation aims to give a basic understanding about the various drug reactions. It explains the mechanisms of ADR, Types, predisposing factors for ADR, and other common drug related adverse events
This slide contains the description of ADR, its dissimilarities with Side effects and toxic effects, types of ADRs, risk Factors and the description of Pharmacovigilance program.
Adverse drug reaction , types ,Detection and Reporting,severity and seriousness(Hartwig'severity assessment), preventibility(Schumock and thornston) and predictability, causality assessment Naranjo"s algotithm, WHO UMC causality scale
ADE
INCIDENCE OF ADR
GREADING OF SEVERITY OF ADR
CLASSIFICATIONS
PHARMACOVIGILANCE
CATAGORIES
CAUSES OF ADR
DRUG INDUCED HEPATIC DYSFUNCTION
DRUG INDUCED ENDOCRINE DYSFUNCTION
DRUG INDUCED PHERIPHERAL NEUROPATHY
MANAGEMENT OF ADR
• Definition of terms associated with Adverse Drug Reactions (ADRs)
• Classification of ADRs
• Discussion on each type of ADR with examples
• Role of the Pharmacists
This slide contains the description of ADR, its dissimilarities with Side effects and toxic effects, types of ADRs, risk Factors and the description of Pharmacovigilance program.
Adverse drug reaction , types ,Detection and Reporting,severity and seriousness(Hartwig'severity assessment), preventibility(Schumock and thornston) and predictability, causality assessment Naranjo"s algotithm, WHO UMC causality scale
ADE
INCIDENCE OF ADR
GREADING OF SEVERITY OF ADR
CLASSIFICATIONS
PHARMACOVIGILANCE
CATAGORIES
CAUSES OF ADR
DRUG INDUCED HEPATIC DYSFUNCTION
DRUG INDUCED ENDOCRINE DYSFUNCTION
DRUG INDUCED PHERIPHERAL NEUROPATHY
MANAGEMENT OF ADR
• Definition of terms associated with Adverse Drug Reactions (ADRs)
• Classification of ADRs
• Discussion on each type of ADR with examples
• Role of the Pharmacists
This Presentation will give you a brief outlook on Pharmacovigilance which will be very useful for every Healthcare professional besides Public awareness.
Pharmacovigilance is the pharmaceutical science relating to the collection, detection, assessment, monitoring, and prevention of adverse effects with pharmaceutical products.
The obtained information is entered in the drug safety database, analyzed, and assessed by the experts to identify new signals.
Signal: Reported information on a possible causal relationship between an adverse event and a drug, of which the relationship is unknown or incompletely documented
previously.
The information generated on the basis of these reports helps in continuous assessment of the benefit-risk ratio of the medicines.
***** Thalidomide was first marketed in 1957 in West Germany, where it was available over the counter.When first released, thalidomide was promoted for anxiety, trouble sleeping, "tension", and morning sickness.While it was initially thought to be safe in pregnancy, concerns regarding birth defects arose until the medication was removed from the market in Europe in 1961.The total number of infants affected by use during pregnancy is estimated at 10,000, of which about 40% died around the time of birth.Those who survived had limb, eye, urinary tract, and heart problems. ****
Adverse drug reaction and pharmacovigilance.Shrawan Gehlot
Any unwanted or undesirable effect or noxious change due to a drug which occurs at doses used in human for prophylaxis, diagnosis or therapy, are known as Adverse Drug Reaction.
Pharmacovigilance is concerned with the detection, assessment and prevention of adverse reaction of drug.
Pharmacovigilance (PV) is defined as the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem.
a presentation in CME activities by Saad Specialist Hospital, KSA
Drugs for prophylaxis of Myocardial InfarctionJervinM
Drugs for prophylaxis of Myocardial Infarction
Myocardial Infarction
Drugs for primary prevention of MI
Drugs for secondary prevention of MI
Recent advances
Cardiac rehabilitation
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
5. Pharmacovigilance
• Science & activities related to
1. Detection
2. Assessment
3. Understanding
4. Prevention
Of ADR or any drug related problems
20/12/2018 5
9. 4. Intolerance
• @ therapeutic doses
• Appearance of characteristic toxic effects
of a drug in an individual
• Low threshold for drug
• E.g. carbamazepine -> ataxia
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10. 5. Idiosyncrasy
• Genetically determined abnormal
reactivity to a chemical
• E.g. barbiturates -> excitation & confusion
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11. 6. Drug allergy
• Immunologically mediated reactions
• Body considers drug as allergen
• Seen in small proportion of population
• Types : I , II, III, IV
• Rx :
O2,
Inj. Adrenaline 0.5mg (1:1000) im / 1:10,000 iv
Antihistamines
Glucocorticoids
• Prevention
– Skin tests (type I)
• Eg . Penicillins
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12. 7. Photosensitivity
• Cutaneous reactions resulting from drug
induced sensitization of skin to UV rays
• Phototoxic
• Photo allergic
20/12/2018 12
15. 8. Drug dependence
• Psychological dependence
– E.g. Opioids, cocaine
• Physical dependence
– E.g. Opioids, barbiturates, alcohol
• Drug abuse
• Drug addiction
• Drug habituation
– E.g. Tea, coffee, smoking
20/12/2018 15
16. 9. Drug withdrawal
• Adverse consequences in sudden
interruption of therapy
• E.g. Angina worsens when β-blockers
stopped suddenly
20/12/2018 16
17. 10. Teratogenicity
• Capacity of a drug to cause foetal
abnormalities when given to pregnant
mother
• 3 Stages:
– Fertilization & Implantation (0-17)-Failure of
pregnancy
– Organogenesis† (18-55)- deformities
– Growth & development (56-) : Developmental
& functional abnormalities
• Avoided in pregnancy
20-12-2018 17
18. Risk category
• A – Human studies – No risk
• B - Animal Studies – No risk
• C – Potential benefit, no proper evidence
• D- Evidence of human foetal risk but
potential benefits outweigh
• X – potential risk
20/12/2018 18
21. 11. Mutagenicity & Carinogenicity
• Capacity of a drug to cause genetic defects
• Capacity of a drug to cause cancer
• Eg:
–Anticancer drugs
–Radioisotopes
–Tobaco
20/12/2018 21
