..butterfly pattern” on the face .This is the typical ”malar rash”
Livedo reticularis
A mottled purplish discoloration of the skin
Subacute Cutaneous Lupus
   erythematosus)SCLE
?What Is Lupus
Lupus Symptom :Joint Pain
Lupus Symptom :Butterfly Rash
Lupus Symptom :Nail Changes
Lupus Symptoms :Fever and
         Fatigue

                            . •
Lupus Symptom :Light
     Sensitivity
Lupus Symptom :Hair Loss


                       . •
Lupus Symptom :Raynaud's
?Lupus or Something Else
Diagnosing Lupus
•
                 ?Who Gets Lupus
    Anyone , But more than 90% of people are women. :
•   African-American, Latino, or Asian
•   Aged 15 to 45
•   Related to someone with lupus
Types of Lupus
•   systemic lupus erythematosus (SLE)
•    Cutaneous lupus erythematosus (discoid lupus
•   Drug-induced systemic lupus
Medical Treatments for Lupus

                          . •
Self-Care for Lupus
•   Cover up when you're in the sun
•   Don't smoke.
•   Exercise regularly.
•   Improve your stress management skills.
•   Also be sure to get plenty of rest..
Lupus and Kidney Problems
Lupus and Heart Problems

                           . •
Lupus and Lung Problems
Lupus and Digestive Problems
Lupus and Anemia
Lupus and the Nervous System
Lupus and Mental Health
Lupus and Pregnancy
Neonatal Lupus
Living with Lupus
Outlook for Lupus
Discoid lupus erythematosus
Subacute LE
Drug-induced lupus
Systemic LE
Livedo reticularis can be a normal condition that is simply more          •
                         .obvious when a person is exposed to the cold
   Livedo reticularis can also be an indicator of impaired circulation.        •
             :Livedo reticularis has been reported in association with
      .Autoimmune diseases such as systemic lupus erythematosus                •
        Abnormal antibodies referred to as phospholipid antibodies.            •
       Examples of these antibodies are the cardiolipin antibody and
                                      .falsely positive testing for syphilis
   A syndrome featuring phospholipid antibodies with multiple brain            •
strokes .It is felt that the blood of these patients has a propensity to
                                   .clot which may predispose to stroke
Erythematous, warm, plaques in light •
    exposed distribution(also on patient's
   neck), consistent with recrudesence of
       known Subacute Cutaneous Lupus
Erythematosus(SCLE ).Image courtesy of
                        .Diego Jarrin, M.D
Joint and muscle pain is often the first sign •
 of lupus .This pain tends to occur on both
        sides of the body at the same time,
       particularly in the joints of the wrists,
      hands, elbows, knees, or ankles .The
 joints may look inflamed and feel warm to
  the touch .But unlike rheumatoid arthritis,
   lupus usually does not cause permanent
                                 .joint damage
A tell-tale sign of lupus is a butterfly- •
shaped rash across the cheeks and bridge
 of the nose .Other common skin problems
include sensitivity to the sun with flaky, red
    spots or a scaly, purple rash on various
parts of the body, including the face, neck,
      and arms .Some people also develop
                            .mouth or lip sores
Lupus can cause the nails to crack or fall •
 off .They may be discolored with blue or
  reddish spots at the base .These spots
 are actually in the nail bed, the result of
   inflamed small blood vessels .Swelling
may also make the skin around the base
            .of the nail look red and puffy
The symptoms of lupus tend to come and •
   go, and this includes hair loss .Patients
  may go through periods where their hair
falls out in patches or becomes thinner all
     across the scalp .Once the flare-up is
  over, new hair is likely to grow in evenly
Some people with lupus develop a condition •
    called Raynaud's phenomenon .Their fingers
    and toes become painful, numb, and tingly in
     response to cold temperatures or emotional
 stress .This happens when small blood vessels
spasm and restrict blood flow to the area .During
an attack, the fingers and toes may turn white or
  blue .People can also have Raynaud's without
               having lupus or any serious health
                                   .complications
When lupus begins, it can look a lot like •
   rheumatoid arthritis, which causes joint
  pain and swelling, or fibromyalgia, which
 causes fatigue and pain .One aspect that
sets lupus apart is the combination of skin
  rashes with joint pain and fatigue .There
are also lab tests that can help distinguish
                 lupus from other diseases
                                            . •
Diagnosing lupus can be tricky .The disease can •
       mimic other conditions, and it often takes a
different course in different people .Many people
       have it for years before developing tell-tale
      symptoms .Although there is no one test for
      lupus, certain proteins usually show up in a
       patient's blood .A blood test for antinuclear
     antibodies(ANAs )can provide a critical clue.
    Other lab tests may check cell counts, kidney
       function, and clotting time .A tissue biopsy
                  .sometimes helps with diagnosis
Digestive problems are not common with •
  lupus, but some people may experience
     belly pain, nausea, vomiting, difficulty
swallowing, or inflammation of the liver or
    pancreas .This can be related to lupus
     itself or medications used to treat the
disease .Some people tend to lose weight
                    .during lupus flare-ups
Depression and anxiety are a risk for people with •
  lupus .This may be the result of the condition's
 affect on the nervous system combined with the
 emotional strain of coping with a chronic illness.
     Be sure to discuss any concerns about your
       mood with your doctor or other health care
   provider .There are highly effective treatments
                       for depression and anxiety
                                                  . •
Most women with lupus can get pregnant, •
       though the condition increases the risk of
complications during pregnancy .Because lupus
   symptoms come and go, the best time to get
 pregnant is when symptoms are at a minimum.
  Women who conceive when symptoms are in
    remission are less likely to have flare-ups or
     complications .Make sure your obstetrician
knows you have lupus .You medications may be
modified and you may undergo extra monitoring
             .to ensure a successful pregnancy
Most babies born to women with lupus are •
     entirely healthy .But in rare cases, the
   newborn of a mom with lupus may have
neonatal lupus .This condition can cause a
  skin rash, anemia, or liver problems .The
     symptoms usually go away after a few
        months and don't cause permanent
      damage .However, some babies with
     neonatal lupus are born with a serious
                                 .heart defect
The fatigue and joint pain associated with •
 lupus can make it more difficult to do your
     job or care for your children .You may
    have to cut back on activities or ask for
   help when symptoms flare up .But most
people with lupus are able to continue with
                       .their usual activities
Thanks to improvements in treatments for •
  lupus, people with the condition are living
    significantly longer .The outlook for any
   given individual depends on how severe
       the disease is, and whether any vital
 organs are affected .But most people with
lupus can expect to live a normal or nearly
                            .normal life span

Acute systemic lupus erythematosus

  • 1.
    ..butterfly pattern” onthe face .This is the typical ”malar rash”
  • 3.
    Livedo reticularis A mottledpurplish discoloration of the skin
  • 5.
    Subacute Cutaneous Lupus erythematosus)SCLE
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
    Lupus Symptoms :Feverand Fatigue . •
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
    ?Who Gets Lupus Anyone , But more than 90% of people are women. : • African-American, Latino, or Asian • Aged 15 to 45 • Related to someone with lupus
  • 17.
    Types of Lupus • systemic lupus erythematosus (SLE) • Cutaneous lupus erythematosus (discoid lupus • Drug-induced systemic lupus
  • 18.
  • 19.
    Self-Care for Lupus • Cover up when you're in the sun • Don't smoke. • Exercise regularly. • Improve your stress management skills. • Also be sure to get plenty of rest..
  • 20.
  • 21.
    Lupus and HeartProblems . •
  • 22.
  • 23.
  • 24.
  • 25.
    Lupus and theNervous System
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 40.
  • 43.
  • 46.
  • 49.
    Livedo reticularis canbe a normal condition that is simply more • .obvious when a person is exposed to the cold Livedo reticularis can also be an indicator of impaired circulation. • :Livedo reticularis has been reported in association with .Autoimmune diseases such as systemic lupus erythematosus • Abnormal antibodies referred to as phospholipid antibodies. • Examples of these antibodies are the cardiolipin antibody and .falsely positive testing for syphilis A syndrome featuring phospholipid antibodies with multiple brain • strokes .It is felt that the blood of these patients has a propensity to .clot which may predispose to stroke
  • 50.
    Erythematous, warm, plaquesin light • exposed distribution(also on patient's neck), consistent with recrudesence of known Subacute Cutaneous Lupus Erythematosus(SCLE ).Image courtesy of .Diego Jarrin, M.D
  • 51.
    Joint and musclepain is often the first sign • of lupus .This pain tends to occur on both sides of the body at the same time, particularly in the joints of the wrists, hands, elbows, knees, or ankles .The joints may look inflamed and feel warm to the touch .But unlike rheumatoid arthritis, lupus usually does not cause permanent .joint damage
  • 52.
    A tell-tale signof lupus is a butterfly- • shaped rash across the cheeks and bridge of the nose .Other common skin problems include sensitivity to the sun with flaky, red spots or a scaly, purple rash on various parts of the body, including the face, neck, and arms .Some people also develop .mouth or lip sores
  • 53.
    Lupus can causethe nails to crack or fall • off .They may be discolored with blue or reddish spots at the base .These spots are actually in the nail bed, the result of inflamed small blood vessels .Swelling may also make the skin around the base .of the nail look red and puffy
  • 54.
    The symptoms oflupus tend to come and • go, and this includes hair loss .Patients may go through periods where their hair falls out in patches or becomes thinner all across the scalp .Once the flare-up is over, new hair is likely to grow in evenly
  • 55.
    Some people withlupus develop a condition • called Raynaud's phenomenon .Their fingers and toes become painful, numb, and tingly in response to cold temperatures or emotional stress .This happens when small blood vessels spasm and restrict blood flow to the area .During an attack, the fingers and toes may turn white or blue .People can also have Raynaud's without having lupus or any serious health .complications
  • 56.
    When lupus begins,it can look a lot like • rheumatoid arthritis, which causes joint pain and swelling, or fibromyalgia, which causes fatigue and pain .One aspect that sets lupus apart is the combination of skin rashes with joint pain and fatigue .There are also lab tests that can help distinguish lupus from other diseases . •
  • 57.
    Diagnosing lupus canbe tricky .The disease can • mimic other conditions, and it often takes a different course in different people .Many people have it for years before developing tell-tale symptoms .Although there is no one test for lupus, certain proteins usually show up in a patient's blood .A blood test for antinuclear antibodies(ANAs )can provide a critical clue. Other lab tests may check cell counts, kidney function, and clotting time .A tissue biopsy .sometimes helps with diagnosis
  • 58.
    Digestive problems arenot common with • lupus, but some people may experience belly pain, nausea, vomiting, difficulty swallowing, or inflammation of the liver or pancreas .This can be related to lupus itself or medications used to treat the disease .Some people tend to lose weight .during lupus flare-ups
  • 59.
    Depression and anxietyare a risk for people with • lupus .This may be the result of the condition's affect on the nervous system combined with the emotional strain of coping with a chronic illness. Be sure to discuss any concerns about your mood with your doctor or other health care provider .There are highly effective treatments for depression and anxiety . •
  • 60.
    Most women withlupus can get pregnant, • though the condition increases the risk of complications during pregnancy .Because lupus symptoms come and go, the best time to get pregnant is when symptoms are at a minimum. Women who conceive when symptoms are in remission are less likely to have flare-ups or complications .Make sure your obstetrician knows you have lupus .You medications may be modified and you may undergo extra monitoring .to ensure a successful pregnancy
  • 61.
    Most babies bornto women with lupus are • entirely healthy .But in rare cases, the newborn of a mom with lupus may have neonatal lupus .This condition can cause a skin rash, anemia, or liver problems .The symptoms usually go away after a few months and don't cause permanent damage .However, some babies with neonatal lupus are born with a serious .heart defect
  • 62.
    The fatigue andjoint pain associated with • lupus can make it more difficult to do your job or care for your children .You may have to cut back on activities or ask for help when symptoms flare up .But most people with lupus are able to continue with .their usual activities
  • 63.
    Thanks to improvementsin treatments for • lupus, people with the condition are living significantly longer .The outlook for any given individual depends on how severe the disease is, and whether any vital organs are affected .But most people with lupus can expect to live a normal or nearly .normal life span