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Acquired Heart Disease
BHAVANA RAJANNA
89A
Outline
2
• Definition
• Etiology
• Pathogenesis
• Diagnosis and c/f
• Treatment
DEFINITION:
3
• Acquired heart diseases
are conditions affecting
the heart and its
associated blood vessels
that develop during a
person's lifetime, in
contrast to congenital heart
diseases, which are present
at birth.
Etiology
5
• They can be caused by illnesses such as a
bacterial or viral infection.
• Viridans type streptococci.
• Staphylococcus aureus,
• Group D enterococci ( lower GI or GU manipulation)
• Others pseudomonas aeruginosa in IVDA
Epidemiology
Acquired HD Mario's 5/21/2018 6
• Males are commonly affected
• IE is often a complication of congenital or Rheumatic
Heart Disease
• Can occur in children with out any abnormal valves or
cardiac malformation
• In developed countries CHD is commonest
predisposing factor
Pathogenesis
Acquired HD Mario's 5/21/2018 7
• Patients with CHD where there is a turbulent blood
flow, if there is high pressure gradient across the
defect, turbulent flow Traumatizes the Endothelium,
creates a substrate for deposition of fibrin and
platelets
• Formation of non bacterial thrombotic embolus
which is initiating lesion for IE
• Transient bacteremia there will be colonization of
NBTE by bacteria and Bacterial proliferation occurs
Risk factor
Acquired HD Mario's 5/21/2018 8
• Intravenous Drug use
• Prosthetic heart valves
• Structural Heart Disease(CHD/RHD)
• Central venous catheter
• Dental, Intestinal or Urinary tract procedure
In 30% a predisposing factor is identified
Clinical Manifestation
Acquired HD Mario's 5/21/2018 9
• Onset may be acute and severe with HGIF and
prostration
• Prolonged fever without other manifestations
• Common Symptoms are
• Myalgia, arthralgia, headache, nausea and vomiting
Physical Examination
Acquired HD Mario's 5/21/2018 10
• New/ changing heart murmur
• Splenomegaly
• Signs of Heart Failure
• clubbing
• Classic skin findings develop late in the course of the
disease
• Osler Nodes (tender pea sized intradermal nodules in the pads of
fingers)
• Janeway Leshions (painless small hemorrhagic lesions on palms and soles)
• Splinter Hemorrhages
• This lesions may represent vasculitis prodiced by Ag-Ab Complex
Treatment
• Antibiotics: regardless of throat culture result
• Amoxicillin PO for 10 days
• Single IM benzathine penicillin
Anti-inflammatory Therapy:
• Asprin
• corticosteroids
Surgical treatment:
• Some childhood heart defects require repairs that can only be
made through open-heart surgery. These repairs may be
needed right away, or they may be delayed for months or even
years. Sometimes repairs can be made in a single surgical
procedure. Other times, a series of operations may be needed.
It all depends on the type and severity of the heart defect and
how sick the patient is.
Acquired HD Mario's 5/21/2018 13

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acqired heart diseases.pptx

  • 2. Outline 2 • Definition • Etiology • Pathogenesis • Diagnosis and c/f • Treatment
  • 3. DEFINITION: 3 • Acquired heart diseases are conditions affecting the heart and its associated blood vessels that develop during a person's lifetime, in contrast to congenital heart diseases, which are present at birth.
  • 4.
  • 5. Etiology 5 • They can be caused by illnesses such as a bacterial or viral infection. • Viridans type streptococci. • Staphylococcus aureus, • Group D enterococci ( lower GI or GU manipulation) • Others pseudomonas aeruginosa in IVDA
  • 6. Epidemiology Acquired HD Mario's 5/21/2018 6 • Males are commonly affected • IE is often a complication of congenital or Rheumatic Heart Disease • Can occur in children with out any abnormal valves or cardiac malformation • In developed countries CHD is commonest predisposing factor
  • 7. Pathogenesis Acquired HD Mario's 5/21/2018 7 • Patients with CHD where there is a turbulent blood flow, if there is high pressure gradient across the defect, turbulent flow Traumatizes the Endothelium, creates a substrate for deposition of fibrin and platelets • Formation of non bacterial thrombotic embolus which is initiating lesion for IE • Transient bacteremia there will be colonization of NBTE by bacteria and Bacterial proliferation occurs
  • 8. Risk factor Acquired HD Mario's 5/21/2018 8 • Intravenous Drug use • Prosthetic heart valves • Structural Heart Disease(CHD/RHD) • Central venous catheter • Dental, Intestinal or Urinary tract procedure In 30% a predisposing factor is identified
  • 9. Clinical Manifestation Acquired HD Mario's 5/21/2018 9 • Onset may be acute and severe with HGIF and prostration • Prolonged fever without other manifestations • Common Symptoms are • Myalgia, arthralgia, headache, nausea and vomiting
  • 10. Physical Examination Acquired HD Mario's 5/21/2018 10 • New/ changing heart murmur • Splenomegaly • Signs of Heart Failure • clubbing • Classic skin findings develop late in the course of the disease • Osler Nodes (tender pea sized intradermal nodules in the pads of fingers) • Janeway Leshions (painless small hemorrhagic lesions on palms and soles) • Splinter Hemorrhages • This lesions may represent vasculitis prodiced by Ag-Ab Complex
  • 11. Treatment • Antibiotics: regardless of throat culture result • Amoxicillin PO for 10 days • Single IM benzathine penicillin Anti-inflammatory Therapy: • Asprin • corticosteroids
  • 12. Surgical treatment: • Some childhood heart defects require repairs that can only be made through open-heart surgery. These repairs may be needed right away, or they may be delayed for months or even years. Sometimes repairs can be made in a single surgical procedure. Other times, a series of operations may be needed. It all depends on the type and severity of the heart defect and how sick the patient is.
  • 13. Acquired HD Mario's 5/21/2018 13