The document discusses plans for the Cheshire and Mersey Comprehensive Local Research Network (CLRN) and its transition to the North West Coast CLRN. It outlines objectives to double recruitment, increase commercial study participation, and reduce approval times. It aims to ensure a fit structure under major health system changes by creating 15 Local Clinical Research Networks including the North West Coast CLRN covering Cheshire, Mersey, South Cumbria and Lancashire with an £18 million budget. The CLRN will promote research delivery, public engagement, and build research capacity across the region in partnership with the Academic Health Science Network.