The document discusses the relationship between the Manchester Academic Health Science Centre (MAHSC) and the Greater Manchester Academic Health Science Network (GM-AHSN). It outlines that MAHSC members host many of the key assets that support GM-AHSN's business plan and that GM-AHSN's domains will help implement NICE guidelines and technologies across Greater Manchester. It also provides examples of MAHSC's expertise in areas like systems biology, clinical research infrastructure, and implementation science. Finally, it discusses challenges like limited resources and the need for partnership between industry, academia, and the NHS to address issues like an aging population and chronic diseases.