3. INTRODUCTION
Nanosphers are class of “Nanoparticles” , which have
homogeneous structure in the whole particle.
DEFINATION :
Nanospheres are the particles having the size range
between 10-200nm in diameter and they can be amorphous
or crystalline in nature .
They have the ability to protect the drug from “enzymatic
and chemical degradation ”.
4. METHODS OF PREPARATIONS
This includes the following methods
Polymerisation Solvent Solvent Phase inversion
Evaporation displacement temperature method
5. POLYMERIZATION
polymeric compounds
drug
incorporation
removed for stabilization
& polymerization
centrifugation
Polymethylmethacrylate &
polyethylcyanocrylate emulsified
Polymerization of
manomers in
Aqueous
Nanospheres are
formed
Nanospheres
By dissloving in
polymerised
medium
Adsorption onto
nanosphers after
polymerisation is
completed