Complexes of Co(II),Ni(II),Cu(II)and Zn(II) with mixed ligand of 4-aminoantipyrine (4-AAP) and tributylphosphine (PBu3) were prepared in aqueous ethanol with (1:2:2) (M:L:PBu3).
complexes
Synthesis, spectroscopic, magnetic properties and superoxide dismutase (SOD) ...IOSR Journals
Three new ternary copper(II) complexes formulated as [Cu(HIda)(bipy)] 1; [Cu(HIda)(phen)] 2; [Cu(HIda)(dmp)] 3; where HIda =N-(2-hydroxyethyl)-2- iminodiacetic acid ; bipy = 2, 2’- bipyridine; phen = 1,10- phenanthroline; dmp = 2,9-dimethyl 1,10-phenanthroline, have been synthesized and characterized by partial elemental analysis, FAB-mass (m/z), EPR, UV-visible and CV measurements. The magnetic and spectroscopic data of all these complexes 1-3 indicate distorted octahedral geometry. The EPR spectra of these complexes in frozen DMSO solutions showed a single at g ca. 2. The trend in g-value (g||>g>2.0023) suggests that the unpaired electron on copper (II) has dx2–y2 character. The SOD activities of the complexes have been investigated. Antibacterial and antifungal activity of these complexes were also measured and discussed.
This document describes the synthesis and characterization of mixed ligand complexes of Co(II), Ni(II), Cu(II) and Zn(II) with anthranillic acid and tributylphosphine. The complexes were prepared in a 1:2:2 molar ratio of metal to ligands and characterized using various spectroscopic techniques. The complexes were found to have octahedral geometry and were tested for their antimicrobial activity against various bacteria, showing high activity. In summary, mixed ligand metal complexes were successfully synthesized and showed antimicrobial properties.
Micellar Effect On Dephosphorylation Of Bis-4-Chloro-3,5-Dimethylphenylphosph...IOSR Journals
The rate enhancement depends on the hydrophobicity of the nucleophile. The micellar catalyzed reaction between bis-4-chloro-3,5-dimethylphenylphosphate ester and hydroxide or hydroperoxide anions has been examined in buffered medium (pH 8-10). First order rate constant (Kψ) for the reaction of hydroxide ion with bis-4-CDMPP go through maxima with the increasing concentration of cetyltrimethylammoniumbromide (CTABr). Micelles of CTABr very effective catalyst to the reactions of phosphate diesters. Rate constants measured with OH2- ions are approximately twice and thrice than that of OH- ions in presence of CTABr.
Mixed Ligand, Palladium(II) and Platinum(II) Complexes of Tertiary Diphosphin...Karwan Omer
This document summarizes a study that synthesized and characterized mixed ligand palladium(II), platinum(II) complexes with tertiary diphosphine and S-1H benzo[d]imidazole-2-yl benzothioate ligands. The complexes were synthesized in two steps, first forming metal complexes with tertiary diphosphines, then adding the S-1H benzimidazole ligand. The complexes were characterized using techniques such as elemental analysis, infrared spectroscopy, UV-Vis spectroscopy, magnetic susceptibility, and X-ray crystallography. The results indicate the ligand bonds to the metal through the nitrogen atom and the complexes have square planar geometries.
This document summarizes the synthesis and characterization of mixed ligand complexes of a symmetrical Schiff base ligand and nicotinamide with various metal ions. A new symmetrical Schiff base ligand was prepared via the condensation of hydrazine hydrate and 4-hydroxy-3-methoxybenzaldehyde. Mixed ligand complexes were synthesized using a 1:1:2 molar ratio of metal salt, Schiff base ligand, and nicotinamide. The complexes were characterized using various techniques such as elemental analysis, conductivity measurements, IR and UV-Vis spectroscopy, and magnetic susceptibility measurements. The ligand and complexes were also tested for their antimicrobial activity against various bacteria. In general, the complexes showed enhanced antibacterial activity compared to the free ligands
The document summarizes research on the synthesis and characterization of mixed ligand metal complexes derived from ampicillin drug and 4-(dimethylamino)benzaldehyde. A Schiff base ligand was prepared via the condensation of these compounds. Metal complexes were synthesized using Fe(II), Co(II), Ni(II), Cu(II), and Zn(II) with the ligand and nicotinamide. The complexes were characterized using various analytical techniques and showed octahedral geometry. The complexes and ligand were screened for antimicrobial activity against bacteria. The complexes demonstrated higher antimicrobial activity than the free ligand.
METALLO - BIOACTIVE COMPOUNDS AS POTENTIAL NOVEL ANTICANCER THERAPYijac123
Mono and bi-organometallic complexes of Cu(II), Ni(II), Mn(II), Zn(II) and Ag(I) complexes with
oxaloamide ligand has much potential as therapeutic and diagnostic agents. The ligand allows the
thermodynamic and kinetic reactivity of the metal ion to be controlled and also provide a scaffold for
functionalization. Specific examples involving the design of metal complexes as anticancer agents are
discussed. These complexes have been synthesized and characterized by (1H-NMR, mass, IR, UV-VIS,
ESR) spectra, magnetic moments and conductance measurements, elemental and thermal analyses. Molar
conductances in DMF solution indicates that, the complexes are non-electrolytes. The ESR spectra of solid
Cu(II) complexes (2-5) show an axial type indicating a d(X2-y2) ground state with a significant covalent
bond character. However, Mn(II) complex(9), shows an isotropic type indicating an octahedral geometry.
Cytotoxic evolution IC50 of the ligand and its complexes have been carried out. Cu(II) Complexes show
enhanced activity in comparison to the parent ligand or standard drug. Copper is enriched in various
human cancer tissues and is a co-factor essential for tumor angiogenesis processes. However, the use of
copper binding ligand to target tumor, copper could provide a novel strategy for cancer selective
treatment.
Thermodynamics and adsorption studies of rhodamine-b dye onto organoclayInnspub Net
Thermodynamics and adsorption studies were conducted with a dye of Rhoda mine-B (RB) on organoclay (OC). Adsorption of the dye was investigated with an initial dye concentration at pH 7±0.3, 298, 308 and 318 K. The adsorption experiments were carried out isothermally at three different temperatures. The Langmuir and Freundlich isotherm models were used to describe the equilibrium data and the results were discussed in details. The thermodynamic parameters such as standard free energy (∆G°), entropy change (∆S°) and enthalpy (∆H°) were calculated for OC. These values showed that adsorption of RB on OC was a spontaneous and endothermic process.
Synthesis, spectroscopic, magnetic properties and superoxide dismutase (SOD) ...IOSR Journals
Three new ternary copper(II) complexes formulated as [Cu(HIda)(bipy)] 1; [Cu(HIda)(phen)] 2; [Cu(HIda)(dmp)] 3; where HIda =N-(2-hydroxyethyl)-2- iminodiacetic acid ; bipy = 2, 2’- bipyridine; phen = 1,10- phenanthroline; dmp = 2,9-dimethyl 1,10-phenanthroline, have been synthesized and characterized by partial elemental analysis, FAB-mass (m/z), EPR, UV-visible and CV measurements. The magnetic and spectroscopic data of all these complexes 1-3 indicate distorted octahedral geometry. The EPR spectra of these complexes in frozen DMSO solutions showed a single at g ca. 2. The trend in g-value (g||>g>2.0023) suggests that the unpaired electron on copper (II) has dx2–y2 character. The SOD activities of the complexes have been investigated. Antibacterial and antifungal activity of these complexes were also measured and discussed.
This document describes the synthesis and characterization of mixed ligand complexes of Co(II), Ni(II), Cu(II) and Zn(II) with anthranillic acid and tributylphosphine. The complexes were prepared in a 1:2:2 molar ratio of metal to ligands and characterized using various spectroscopic techniques. The complexes were found to have octahedral geometry and were tested for their antimicrobial activity against various bacteria, showing high activity. In summary, mixed ligand metal complexes were successfully synthesized and showed antimicrobial properties.
Micellar Effect On Dephosphorylation Of Bis-4-Chloro-3,5-Dimethylphenylphosph...IOSR Journals
The rate enhancement depends on the hydrophobicity of the nucleophile. The micellar catalyzed reaction between bis-4-chloro-3,5-dimethylphenylphosphate ester and hydroxide or hydroperoxide anions has been examined in buffered medium (pH 8-10). First order rate constant (Kψ) for the reaction of hydroxide ion with bis-4-CDMPP go through maxima with the increasing concentration of cetyltrimethylammoniumbromide (CTABr). Micelles of CTABr very effective catalyst to the reactions of phosphate diesters. Rate constants measured with OH2- ions are approximately twice and thrice than that of OH- ions in presence of CTABr.
Mixed Ligand, Palladium(II) and Platinum(II) Complexes of Tertiary Diphosphin...Karwan Omer
This document summarizes a study that synthesized and characterized mixed ligand palladium(II), platinum(II) complexes with tertiary diphosphine and S-1H benzo[d]imidazole-2-yl benzothioate ligands. The complexes were synthesized in two steps, first forming metal complexes with tertiary diphosphines, then adding the S-1H benzimidazole ligand. The complexes were characterized using techniques such as elemental analysis, infrared spectroscopy, UV-Vis spectroscopy, magnetic susceptibility, and X-ray crystallography. The results indicate the ligand bonds to the metal through the nitrogen atom and the complexes have square planar geometries.
This document summarizes the synthesis and characterization of mixed ligand complexes of a symmetrical Schiff base ligand and nicotinamide with various metal ions. A new symmetrical Schiff base ligand was prepared via the condensation of hydrazine hydrate and 4-hydroxy-3-methoxybenzaldehyde. Mixed ligand complexes were synthesized using a 1:1:2 molar ratio of metal salt, Schiff base ligand, and nicotinamide. The complexes were characterized using various techniques such as elemental analysis, conductivity measurements, IR and UV-Vis spectroscopy, and magnetic susceptibility measurements. The ligand and complexes were also tested for their antimicrobial activity against various bacteria. In general, the complexes showed enhanced antibacterial activity compared to the free ligands
The document summarizes research on the synthesis and characterization of mixed ligand metal complexes derived from ampicillin drug and 4-(dimethylamino)benzaldehyde. A Schiff base ligand was prepared via the condensation of these compounds. Metal complexes were synthesized using Fe(II), Co(II), Ni(II), Cu(II), and Zn(II) with the ligand and nicotinamide. The complexes were characterized using various analytical techniques and showed octahedral geometry. The complexes and ligand were screened for antimicrobial activity against bacteria. The complexes demonstrated higher antimicrobial activity than the free ligand.
METALLO - BIOACTIVE COMPOUNDS AS POTENTIAL NOVEL ANTICANCER THERAPYijac123
Mono and bi-organometallic complexes of Cu(II), Ni(II), Mn(II), Zn(II) and Ag(I) complexes with
oxaloamide ligand has much potential as therapeutic and diagnostic agents. The ligand allows the
thermodynamic and kinetic reactivity of the metal ion to be controlled and also provide a scaffold for
functionalization. Specific examples involving the design of metal complexes as anticancer agents are
discussed. These complexes have been synthesized and characterized by (1H-NMR, mass, IR, UV-VIS,
ESR) spectra, magnetic moments and conductance measurements, elemental and thermal analyses. Molar
conductances in DMF solution indicates that, the complexes are non-electrolytes. The ESR spectra of solid
Cu(II) complexes (2-5) show an axial type indicating a d(X2-y2) ground state with a significant covalent
bond character. However, Mn(II) complex(9), shows an isotropic type indicating an octahedral geometry.
Cytotoxic evolution IC50 of the ligand and its complexes have been carried out. Cu(II) Complexes show
enhanced activity in comparison to the parent ligand or standard drug. Copper is enriched in various
human cancer tissues and is a co-factor essential for tumor angiogenesis processes. However, the use of
copper binding ligand to target tumor, copper could provide a novel strategy for cancer selective
treatment.
Thermodynamics and adsorption studies of rhodamine-b dye onto organoclayInnspub Net
Thermodynamics and adsorption studies were conducted with a dye of Rhoda mine-B (RB) on organoclay (OC). Adsorption of the dye was investigated with an initial dye concentration at pH 7±0.3, 298, 308 and 318 K. The adsorption experiments were carried out isothermally at three different temperatures. The Langmuir and Freundlich isotherm models were used to describe the equilibrium data and the results were discussed in details. The thermodynamic parameters such as standard free energy (∆G°), entropy change (∆S°) and enthalpy (∆H°) were calculated for OC. These values showed that adsorption of RB on OC was a spontaneous and endothermic process.
Spectroscopic, Thermal, Magnetic and conductimetric studies on some 7-hydroxy...IOSR Journals
7-hydroxy-4-methyl-8-(p-methylphenylazo)coumarin (L1) and 7-hydroxy-4-methyl-8-(p-methoxyphenylazo)coumarin (L2) have been prepared and characterized by elemental analysis, infrared (IR), proton nuclear magnetic resonance (1H NMR) and mass spectra. The important infrared (IR) spectral bands corresponding to the active groups in the two ligands and the solid complexes under investigation were studied. Also the important fragments in the ligands and complexes were done using mass spectra and the main peaks were corresponding to the molecular weights of the ligands and complexes. The solid complexes have been synthesized and characterized by elemental and thermal analyses (TG and DTA) as well as by IR, 1H NMR, magnetic measurements, electronic transition, molar conductance, mass and electron spin resonance (ESR) spectra. The proposed steriochemical structures for the investigated metal complexes suggest octahedral geometry with respect to Mn, Co, Ni, Cu and Zn divalent metal ions with the investigated ligands 1:1 and 1:2 complexes and all of the formed complexes contain coordinated and hydrated water molecules. All of the prepared solid complexes behave as non-electrolytes in chloroform.
Reaction of aniline with ammonium persulphate and concentrated hydrochloric a...Maciej Przybyłek
In this paper, the reaction of aniline with ammonium persulphate and concentrated HCl was studied. As a result of our experimental studies, 2,4,6-trichlorophenylamine was identified as the main product. This shows that a high concentration of HCl does not favour oxidative polymerisation of phenylamine, even though the ammonium persulphate/HCl system is widely used in polyaniline synthesis. On the basis of the experimental data and density functional theory for reaction path modelling, we proposed a mechanism for oxidative chlorination of aniline. We assumed that this reaction proceeded in three cyclically repeated steps; protonation of aniline, formation of singlet ground state phenylnitrenium cation, and nucleophilic substitution. In order to confirm this mechanism, kinetic, thermochemical, and natural bond orbital population analyses were performed.
Deciphering reaction mechanism with intermediate trappingDaniel Morton
This module provides an overview of a tool used to gain information on a reaction mechanism; reactive intermediate trapping.
A reactive intermediate is a short-lived, high-energy, highly reactive molecule. When generated in a chemical reaction, it will quickly convert into a more stable molecule. When their existence is indicated, reactive intermediates can help explain how a chemical reaction takes place.
Contributed by:
Shuangyu Ma & Yiling Bi (Undergraduate Students)
University of Utah
2014
New Schiff base ligand (E)-6-(2-(4-
(dimethylamino)benzylideneamino)-2-phenylacetamido)-3,3-
dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic
acid = (HL) Figure(1) was prepared via condensation of
Ampicillin and 4(dimethylamino)benzaldehyde in methanol
.Polydentate mixed ligand complexes were obtained from 1:1:2
molar ratio reactions with metal ions and HL, 2NA on reaction
with MCl2 .nH2O salt yields complexes corresponding to the
formulas [M(L)(NA)2Cl] ,where M =
Fe(II),Co(II),Ni(II),Cu(II),and Zn(II) and NA=nicotinamide.
The 1H-NMR, FT-IR, UV-Vis and elemental analysis
were used for the characterization of the ligand. The complexes
were structurally studied through AAS, FT-IR, UV-Vis,
chloride contents, conductance, and magnetic susceptibility
measurements. All complexes are non-electrolytes in DMSO
solution. Octahedral geometries have been suggested for each
of the complexes. The Schiff base ligands function as
tridentates and the deprotonated enolic form is preferred for
coordination. In order to evaluate the effect of the bactericidal
activity, these synthesized complexes, in comparison to the un
complexed Schiff base has been screened against bacterial
species, Staphy
A new Schiff base 4-chlorophenyl)methanimine
(6R,7R)-3-methyl-8-oxo-7-(2-phenylpropanamido)-5-thia-1-
azabicyclo[4.2.0]oct-2-ene-2-carboxylate= (HL)= C23H20
ClN3O4S) has been synthesized from β-lactam antibiotic
(cephalexin mono hydrate(CephH)=(C16H19N3O5S.H2O) and 4-
chlorobenzaldehyde . Figure(1) Metal mixed ligand complexes
of the Schiff base were prepared from chloride salt of
Fe(II),Co(II),Ni(II),Cu(II),Zn(II) and Cd (II), in 50% (v/v)
ethanol –water medium (SacH ) .in aqueous ethanol(1:1)
containing and Saccharin(C7H5NO3S) = sodium hydroxide.
Several physical tools in particular; IR, CHN, 1H NMR, 13C
NMR for ligand and melting point molar conductance, magnetic
moment. and determination the percentage of the metal in the
complexes by flame(AAS). The ligands and there metal
complexes were screened for their antimicrobial activity against
four bacteria (gram + ve) and (gram -ve) {Escherichia coli,
Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus}.
The proposed structure of the complexes using program, Chem
office 3D(2006). The general formula have been given for the
prepared mixed ligand complexes Na2[M(Sac)3(L)], M(II) = Fe
(II), Co(II) , Ni(II), Cu (II), Zn(II) , and Cd(II).
HL= C29H24 ClN3O4S, L= C29H23 ClN3O4S -.
Determination of Riociguat by Oxidative Coupling Using Visible SpectrophotometryRatnakaram Venkata Nadh
This document describes a simple spectrophotometric method developed to determine the drug riociguat in bulk and tablet formulations. The method is based on the oxidation of MBTH by Fe+3 ions in acidic medium, which forms an active coupling species. This species then couples with riociguat to form a chromophore with a maximum absorption at 660 nm. The method was validated according to ICH guidelines and showed good linearity, reproducibility, accuracy, and precision for the determination of riociguat.
Synthesis, Characterization, Antibacterial and DNA Binding Studies of Mn (II)...IOSRJAC
Mn (II) complex of the Schiff base (L), 3-(2-(2-hydroxy-3-methoxybenzylidene) hydrazinyl) quinoxalin-2(1H)-one (VHQO) was prepared and characterized by IR, UV-VIS, Mass, Elemental analysis, TGDTA, magnetic susceptibility and conductivity measurements. VHQO behaved as monobasic, tridentate ligand and formed 1:2 complex (ML2) with the metal ion (M) coordinating through ring nitrogen, azomethine nitrogen and phenolic oxygen. Thermal analysis of the complex indicated the absence of lattice and coordinated water. Based on the spectral and analytical data, octahedral geometry was assigned to the complex. Antibacterial activity of the complex against gram positive bacteria, Bacillus subtillis, Staphylococcus aureus, and gram negative bacteria, Escherichia coli, Proteus vulgaris, Pseudomonas aeroginosa , and Klebsiella pneumonia was studied. The interaction of the complex with Calf Thymus DNA (CT-DNA) was studied by absorption spectroscopy and the intrinsic binding constant was calculated.
The document summarizes a study on the synthesis, characterization, and antibacterial activity of mixed ligand complexes of Fe(II), Co(II), Ni(II), Cu(II), and Zn(II) with cephalexin and nicotinamide. The complexes were prepared in a 1:1:3 metal to cephalexin to nicotinamide ratio and characterized using various analytical techniques. The complexes exhibited good conductivity and were found to be nonelectrolytes. Infrared spectroscopy showed that cephalexin coordinated through the nitrogen of the amine group and oxygen of the β-lactum group. Nicotinamide coordinated through the pyridine nitrogen. The complexes demonstrated antibacterial activity
This document outlines a study investigating the cage effects of ionic liquids. The goals are to synthesize naphthyl ester starting materials and purify them for use in a photo-Fries reaction probe experiment to quantify cage effects. Naphthyl esters were synthesized from naphthols and acid chlorides. The esters were purified using recrystallization or column chromatography and analyzed for purity using melting point, TLC, and GC/MS. The purified esters will be used in future photolysis experiments coupled with GC/MS to quantify cage effects of ionic liquids and hexanes as a control. This will provide insight into how effectively solute molecules can escape solvent cages in ionic liquids.
Synthesis and characterization of some metal complexes of 2- Phenyl-3,4-dihyd...IOSRJAC
2-Phenyl-3,4-dihydro-quinazolin-4-yloxy)-acetic acid (L1) metal complexes with Mn2+ , Co2+, Ni2+ Cu2+ , and Zn2+ ions were studied and the structure of the complexes were elucidated using elemental analyses, infrared (IR), 1H nuclear magnetic resonance (NMR), magnetic moment and thermal analysis measurements. Besides the characterization of complexes by physicochemical technique, Biological activities of the synthesized complexes were examined against some microbial strains for evaluation of antibacterial and antifungal activities.
Electrochemical, in-vitro in-vivo study of Co (II)-ofloxacin complexIOSR Journals
Ofloxacin complex has been synthesized and screened for its physicochemical, microbial as well as pharmacological activity have been done in solid and aqueous phase. On the basis of elemental analysis, polarographic studies, amperometric titration and IR spectral studies the probable formula for the complex has been determined at 30±1OC and ionic strength of μ= 1.0[KCl]. Raper’s paper disc method was used for microbial study against various pathogenic bacteria and fungi.Invivo syudy of Swiss mice [25-30gm] were used for antibacterial activity against ofloxacin and its complex on xyline-Alcoholic activity test Kidney, liver and serum of these rats were also studied. On the basis of observed result it could be concluded that Co(II)-Ofloxacin complex were found to be non-toxic and more potent than pure Ofloxacin.(1)
Role of mixed ligand Pd(II) and Pt(II)complexes in photooxygenation reactionIOSR Journals
Mixed ligand complexes of the formula [M (phen) bdt] where M= Pd (II) or Pt(II), phen =1,10-phenanthroline and bdt =1,2-benzenedithiolate have been synthesized and studied as photosensitizers of singlet molecular oxygen (1O2) production. It was observed that, Pt (II) complex shows a better photosensitizing ability as compared to its Pd (II) analogue. However, both Pd (II) and Pt (II) complexes act as chemical quenchers of 1O2, resulting in their photooxidation shown by decay of the respective complex. ThusPt (II) complex undergoes selfsensitizedphotooxidation by 1O2. The solvent dependence of this reaction is undertaken by performing the experiment using pure DMF(dimethyl formamide)and 10% H2O in DMF as solvent. The comparison of rate of decay of the Pt(II)and Pd(II) complexes show enhancement of the reaction in presence of water. The decay of the complex was monitored by recording the difference absorption spectra of the complex in the visible region after definite irradiation times. Involvement of 1O2 is further supported by quenching studies of this reaction using NaN3 as physical quencher of 1O2.
Synthesis and Characterization of Schiff Base from Aromatic Amine and Aromati...ijtsrd
The synthesis of Schiff base From Aromatic Amine And Aromatic P Nitro benzaldehyde was performed by a novel method of stirring followed by the addition of p nitro benzaldehydeandm nitro aniline 0.02M . Characterization of the synthesized compounds, determination of purity and identity of the compounds using following spectroscopic and chromatographic techniques Solubility, Thin Layer Chromatographic studies, Ultra Violet studied rotational and vibrational studies FT IR studies. The compounds were investigated for their Antimicrobial activity by cup plate method. Compound1 nitro 4 1 imino,4 nitrophenyl benzene was found to be the most active according to pharmacological evaluation exhibited antimicrobial. Ms. Chetana D. Patil | Mr. Digamber N. Bhosale | Ms. Smita P. Bedis "Synthesis and Characterization of Schiff Base from Aromatic Amine and Aromatic P-Nitro Benzaldehyde" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-5 , August 2019, URL: https://www.ijtsrd.com/papers/ijtsrd26401.pdfPaper URL: https://www.ijtsrd.com/pharmacy/medicinal-chemistry/26401/synthesis-and-characterization-of-schiff-base-from-aromatic-amine-and-aromatic-p-nitro-benzaldehyde/ms-chetana-d-patil
This article describes the synthesis of unusual trimers from 1,3-indandione using DMSO-acetic anhydride. When 1,3-indandione was reacted with pre-heated DMSO-acetic anhydride at waterbath temperature, it produced an unusual trimer (4) and a novel compound (5), methine-tris-1,3-indandione, along with the ylide (2). The structures of the trimer (4) and novel compound (5) were determined using spectral data and proposed reaction mechanisms. This research demonstrated the first observation of a methine-tris derivative being formed from the reaction of 1,3-indand
Spectral studies of 5-({4-amino-2-[(Z)-(2-hydroxybenzylidene) amino] pyrimidi...IOSR Journals
Some transition metal ions Complexes with 5-({4-amino-2-[(Z)-(2-hydroxybenzylidene) amino]
pyrimidin-5-yl} methyl)-2,3,4-trimethoxybenzene were prepared and characterized by elemental analyses,
Infrared , magnetic moment, electronic spectra , mass spectra, X-ray powder diffraction, molar conductance
and thermal analysis (TGA). The complexes have general formulae [ML2.2H2O] {where M = Mn (II), Co (II), Ni
(II), Cu (II), Zn (II), Pd (II) and Pt (II). The coordination behavior of the metal ions towards to the investigated
Schiff base takes place through –C=N,-NH2 and –OH groups. The obtained C, H and N elemental analysis data
showed the Metal: Ligand ratio is 1:2 [M: L] ratio. The molar conductance data reveal that all the metal
complexes are non-electrolytic in nature. From the magnetic moments the complexes are paramagnetic except
Zn metal ion complexes have octahedral geometry with coordination number eight. The thermal behavior of
these complexes shows that, the hydrated complexes have loses two water molecules and immediately followed
by decomposition of the anions and ligand molecules in the second and third stage. The Schiff bases and metal
complexes show good activity against some bacteria. The antimicrobial results indicate that, the metal
complexes have better antimicrobial activity as compared to the prepared Schiff base.
Synthesis, Spectroscopic study & Biological Activity Of Some Organotin(Iv) De...IOSR Journals
Some di-and triorganotin(IV) derivatives of (2E)-N-methyl-(2
oxo1,2diphenylethylidne)hydrazinecarbothioamide synthesised by the reactions of the corresponding di and
triorganotin(IV) chlorides with the sodium salt of (2E)-N-methyl-(2-
oxo1,2diphenylethylidne)hydrazinecarbothioamide in different molar ratios. These derivatives have been
characterized by elemental analyses ,molecular weights, conductivity measurements and spectral(IR, 1H, 13C
and 119 Sn NMR) studies.
This document describes the synthesis, spectral characterization, and biological screening of transition metal complexes of the ligand 2-(5-mercapto-1,3,4-oxadiazol-2-yl)phenol. A series of complexes were prepared using Cu(II), Co(II), Ni(II), and Zn(II) and characterized using analytical data, magnetic susceptibility, IR, UV-Vis, 1H NMR, 13C NMR, EPR, and other techniques. Spectral data suggest an octahedral geometry around the metal ion. Biological screening showed the complexes have antibacterial, antifungal, and DNA cleavage activities.
Its related to Study of gene metal-ligand stability constant of cefadroxil with cu2+ metal ion ph metrically at 0.1 m ionic strength. Also describe another Parameters.
1. The document describes the synthesis and characterization of novel Schiff base ligands and their transition metal complexes.
2. Several heterocyclic aldehydes and aniline derivatives were synthesized and used to prepare Schiff bases. These include Schiff bases derived from 4-methylumbelliferone and N-methylpropane-1,3-diamine.
3. The Schiff bases were characterized using analytical techniques like NMR, MS and IR spectroscopy. They were then used to prepare transition metal complexes which will be explored for potential biological activities.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
Max mosley f1 rules-livery numbers - pdfMax Mosley
The FIA is changing the requirements for obtaining a Super Licence needed to compete in Formula One racing. Beginning in 2016, drivers will need to accumulate 40 points over three years based on their results in other motorsport series. They will also need a valid road license, pass a test on F1 regulations, and complete 300km in a recent F1 car. The document provides details on the point allocation system and other rule modifications.
This document summarizes key aspects of safe harbor laws, which are designed to protect domestic minor victims of sex trafficking. The main points are:
1) Safe harbor laws require that sexually exploited minors be provided specialized services instead of facing criminal charges. They also impose higher penalties on buyers and traffickers.
2) Key elements of safe harbor laws include protecting minors, providing them services, and increasing penalties for traffickers/buyers. Training for law enforcement is also important.
3) Important court cases and studies show that arresting and detaining minor victims is re-traumatizing and ineffective, while specialized programs have improved victims' well-being. Safe harbor laws aim to
Spectroscopic, Thermal, Magnetic and conductimetric studies on some 7-hydroxy...IOSR Journals
7-hydroxy-4-methyl-8-(p-methylphenylazo)coumarin (L1) and 7-hydroxy-4-methyl-8-(p-methoxyphenylazo)coumarin (L2) have been prepared and characterized by elemental analysis, infrared (IR), proton nuclear magnetic resonance (1H NMR) and mass spectra. The important infrared (IR) spectral bands corresponding to the active groups in the two ligands and the solid complexes under investigation were studied. Also the important fragments in the ligands and complexes were done using mass spectra and the main peaks were corresponding to the molecular weights of the ligands and complexes. The solid complexes have been synthesized and characterized by elemental and thermal analyses (TG and DTA) as well as by IR, 1H NMR, magnetic measurements, electronic transition, molar conductance, mass and electron spin resonance (ESR) spectra. The proposed steriochemical structures for the investigated metal complexes suggest octahedral geometry with respect to Mn, Co, Ni, Cu and Zn divalent metal ions with the investigated ligands 1:1 and 1:2 complexes and all of the formed complexes contain coordinated and hydrated water molecules. All of the prepared solid complexes behave as non-electrolytes in chloroform.
Reaction of aniline with ammonium persulphate and concentrated hydrochloric a...Maciej Przybyłek
In this paper, the reaction of aniline with ammonium persulphate and concentrated HCl was studied. As a result of our experimental studies, 2,4,6-trichlorophenylamine was identified as the main product. This shows that a high concentration of HCl does not favour oxidative polymerisation of phenylamine, even though the ammonium persulphate/HCl system is widely used in polyaniline synthesis. On the basis of the experimental data and density functional theory for reaction path modelling, we proposed a mechanism for oxidative chlorination of aniline. We assumed that this reaction proceeded in three cyclically repeated steps; protonation of aniline, formation of singlet ground state phenylnitrenium cation, and nucleophilic substitution. In order to confirm this mechanism, kinetic, thermochemical, and natural bond orbital population analyses were performed.
Deciphering reaction mechanism with intermediate trappingDaniel Morton
This module provides an overview of a tool used to gain information on a reaction mechanism; reactive intermediate trapping.
A reactive intermediate is a short-lived, high-energy, highly reactive molecule. When generated in a chemical reaction, it will quickly convert into a more stable molecule. When their existence is indicated, reactive intermediates can help explain how a chemical reaction takes place.
Contributed by:
Shuangyu Ma & Yiling Bi (Undergraduate Students)
University of Utah
2014
New Schiff base ligand (E)-6-(2-(4-
(dimethylamino)benzylideneamino)-2-phenylacetamido)-3,3-
dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic
acid = (HL) Figure(1) was prepared via condensation of
Ampicillin and 4(dimethylamino)benzaldehyde in methanol
.Polydentate mixed ligand complexes were obtained from 1:1:2
molar ratio reactions with metal ions and HL, 2NA on reaction
with MCl2 .nH2O salt yields complexes corresponding to the
formulas [M(L)(NA)2Cl] ,where M =
Fe(II),Co(II),Ni(II),Cu(II),and Zn(II) and NA=nicotinamide.
The 1H-NMR, FT-IR, UV-Vis and elemental analysis
were used for the characterization of the ligand. The complexes
were structurally studied through AAS, FT-IR, UV-Vis,
chloride contents, conductance, and magnetic susceptibility
measurements. All complexes are non-electrolytes in DMSO
solution. Octahedral geometries have been suggested for each
of the complexes. The Schiff base ligands function as
tridentates and the deprotonated enolic form is preferred for
coordination. In order to evaluate the effect of the bactericidal
activity, these synthesized complexes, in comparison to the un
complexed Schiff base has been screened against bacterial
species, Staphy
A new Schiff base 4-chlorophenyl)methanimine
(6R,7R)-3-methyl-8-oxo-7-(2-phenylpropanamido)-5-thia-1-
azabicyclo[4.2.0]oct-2-ene-2-carboxylate= (HL)= C23H20
ClN3O4S) has been synthesized from β-lactam antibiotic
(cephalexin mono hydrate(CephH)=(C16H19N3O5S.H2O) and 4-
chlorobenzaldehyde . Figure(1) Metal mixed ligand complexes
of the Schiff base were prepared from chloride salt of
Fe(II),Co(II),Ni(II),Cu(II),Zn(II) and Cd (II), in 50% (v/v)
ethanol –water medium (SacH ) .in aqueous ethanol(1:1)
containing and Saccharin(C7H5NO3S) = sodium hydroxide.
Several physical tools in particular; IR, CHN, 1H NMR, 13C
NMR for ligand and melting point molar conductance, magnetic
moment. and determination the percentage of the metal in the
complexes by flame(AAS). The ligands and there metal
complexes were screened for their antimicrobial activity against
four bacteria (gram + ve) and (gram -ve) {Escherichia coli,
Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus}.
The proposed structure of the complexes using program, Chem
office 3D(2006). The general formula have been given for the
prepared mixed ligand complexes Na2[M(Sac)3(L)], M(II) = Fe
(II), Co(II) , Ni(II), Cu (II), Zn(II) , and Cd(II).
HL= C29H24 ClN3O4S, L= C29H23 ClN3O4S -.
Determination of Riociguat by Oxidative Coupling Using Visible SpectrophotometryRatnakaram Venkata Nadh
This document describes a simple spectrophotometric method developed to determine the drug riociguat in bulk and tablet formulations. The method is based on the oxidation of MBTH by Fe+3 ions in acidic medium, which forms an active coupling species. This species then couples with riociguat to form a chromophore with a maximum absorption at 660 nm. The method was validated according to ICH guidelines and showed good linearity, reproducibility, accuracy, and precision for the determination of riociguat.
Synthesis, Characterization, Antibacterial and DNA Binding Studies of Mn (II)...IOSRJAC
Mn (II) complex of the Schiff base (L), 3-(2-(2-hydroxy-3-methoxybenzylidene) hydrazinyl) quinoxalin-2(1H)-one (VHQO) was prepared and characterized by IR, UV-VIS, Mass, Elemental analysis, TGDTA, magnetic susceptibility and conductivity measurements. VHQO behaved as monobasic, tridentate ligand and formed 1:2 complex (ML2) with the metal ion (M) coordinating through ring nitrogen, azomethine nitrogen and phenolic oxygen. Thermal analysis of the complex indicated the absence of lattice and coordinated water. Based on the spectral and analytical data, octahedral geometry was assigned to the complex. Antibacterial activity of the complex against gram positive bacteria, Bacillus subtillis, Staphylococcus aureus, and gram negative bacteria, Escherichia coli, Proteus vulgaris, Pseudomonas aeroginosa , and Klebsiella pneumonia was studied. The interaction of the complex with Calf Thymus DNA (CT-DNA) was studied by absorption spectroscopy and the intrinsic binding constant was calculated.
The document summarizes a study on the synthesis, characterization, and antibacterial activity of mixed ligand complexes of Fe(II), Co(II), Ni(II), Cu(II), and Zn(II) with cephalexin and nicotinamide. The complexes were prepared in a 1:1:3 metal to cephalexin to nicotinamide ratio and characterized using various analytical techniques. The complexes exhibited good conductivity and were found to be nonelectrolytes. Infrared spectroscopy showed that cephalexin coordinated through the nitrogen of the amine group and oxygen of the β-lactum group. Nicotinamide coordinated through the pyridine nitrogen. The complexes demonstrated antibacterial activity
This document outlines a study investigating the cage effects of ionic liquids. The goals are to synthesize naphthyl ester starting materials and purify them for use in a photo-Fries reaction probe experiment to quantify cage effects. Naphthyl esters were synthesized from naphthols and acid chlorides. The esters were purified using recrystallization or column chromatography and analyzed for purity using melting point, TLC, and GC/MS. The purified esters will be used in future photolysis experiments coupled with GC/MS to quantify cage effects of ionic liquids and hexanes as a control. This will provide insight into how effectively solute molecules can escape solvent cages in ionic liquids.
Synthesis and characterization of some metal complexes of 2- Phenyl-3,4-dihyd...IOSRJAC
2-Phenyl-3,4-dihydro-quinazolin-4-yloxy)-acetic acid (L1) metal complexes with Mn2+ , Co2+, Ni2+ Cu2+ , and Zn2+ ions were studied and the structure of the complexes were elucidated using elemental analyses, infrared (IR), 1H nuclear magnetic resonance (NMR), magnetic moment and thermal analysis measurements. Besides the characterization of complexes by physicochemical technique, Biological activities of the synthesized complexes were examined against some microbial strains for evaluation of antibacterial and antifungal activities.
Electrochemical, in-vitro in-vivo study of Co (II)-ofloxacin complexIOSR Journals
Ofloxacin complex has been synthesized and screened for its physicochemical, microbial as well as pharmacological activity have been done in solid and aqueous phase. On the basis of elemental analysis, polarographic studies, amperometric titration and IR spectral studies the probable formula for the complex has been determined at 30±1OC and ionic strength of μ= 1.0[KCl]. Raper’s paper disc method was used for microbial study against various pathogenic bacteria and fungi.Invivo syudy of Swiss mice [25-30gm] were used for antibacterial activity against ofloxacin and its complex on xyline-Alcoholic activity test Kidney, liver and serum of these rats were also studied. On the basis of observed result it could be concluded that Co(II)-Ofloxacin complex were found to be non-toxic and more potent than pure Ofloxacin.(1)
Role of mixed ligand Pd(II) and Pt(II)complexes in photooxygenation reactionIOSR Journals
Mixed ligand complexes of the formula [M (phen) bdt] where M= Pd (II) or Pt(II), phen =1,10-phenanthroline and bdt =1,2-benzenedithiolate have been synthesized and studied as photosensitizers of singlet molecular oxygen (1O2) production. It was observed that, Pt (II) complex shows a better photosensitizing ability as compared to its Pd (II) analogue. However, both Pd (II) and Pt (II) complexes act as chemical quenchers of 1O2, resulting in their photooxidation shown by decay of the respective complex. ThusPt (II) complex undergoes selfsensitizedphotooxidation by 1O2. The solvent dependence of this reaction is undertaken by performing the experiment using pure DMF(dimethyl formamide)and 10% H2O in DMF as solvent. The comparison of rate of decay of the Pt(II)and Pd(II) complexes show enhancement of the reaction in presence of water. The decay of the complex was monitored by recording the difference absorption spectra of the complex in the visible region after definite irradiation times. Involvement of 1O2 is further supported by quenching studies of this reaction using NaN3 as physical quencher of 1O2.
Synthesis and Characterization of Schiff Base from Aromatic Amine and Aromati...ijtsrd
The synthesis of Schiff base From Aromatic Amine And Aromatic P Nitro benzaldehyde was performed by a novel method of stirring followed by the addition of p nitro benzaldehydeandm nitro aniline 0.02M . Characterization of the synthesized compounds, determination of purity and identity of the compounds using following spectroscopic and chromatographic techniques Solubility, Thin Layer Chromatographic studies, Ultra Violet studied rotational and vibrational studies FT IR studies. The compounds were investigated for their Antimicrobial activity by cup plate method. Compound1 nitro 4 1 imino,4 nitrophenyl benzene was found to be the most active according to pharmacological evaluation exhibited antimicrobial. Ms. Chetana D. Patil | Mr. Digamber N. Bhosale | Ms. Smita P. Bedis "Synthesis and Characterization of Schiff Base from Aromatic Amine and Aromatic P-Nitro Benzaldehyde" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-5 , August 2019, URL: https://www.ijtsrd.com/papers/ijtsrd26401.pdfPaper URL: https://www.ijtsrd.com/pharmacy/medicinal-chemistry/26401/synthesis-and-characterization-of-schiff-base-from-aromatic-amine-and-aromatic-p-nitro-benzaldehyde/ms-chetana-d-patil
This article describes the synthesis of unusual trimers from 1,3-indandione using DMSO-acetic anhydride. When 1,3-indandione was reacted with pre-heated DMSO-acetic anhydride at waterbath temperature, it produced an unusual trimer (4) and a novel compound (5), methine-tris-1,3-indandione, along with the ylide (2). The structures of the trimer (4) and novel compound (5) were determined using spectral data and proposed reaction mechanisms. This research demonstrated the first observation of a methine-tris derivative being formed from the reaction of 1,3-indand
Spectral studies of 5-({4-amino-2-[(Z)-(2-hydroxybenzylidene) amino] pyrimidi...IOSR Journals
Some transition metal ions Complexes with 5-({4-amino-2-[(Z)-(2-hydroxybenzylidene) amino]
pyrimidin-5-yl} methyl)-2,3,4-trimethoxybenzene were prepared and characterized by elemental analyses,
Infrared , magnetic moment, electronic spectra , mass spectra, X-ray powder diffraction, molar conductance
and thermal analysis (TGA). The complexes have general formulae [ML2.2H2O] {where M = Mn (II), Co (II), Ni
(II), Cu (II), Zn (II), Pd (II) and Pt (II). The coordination behavior of the metal ions towards to the investigated
Schiff base takes place through –C=N,-NH2 and –OH groups. The obtained C, H and N elemental analysis data
showed the Metal: Ligand ratio is 1:2 [M: L] ratio. The molar conductance data reveal that all the metal
complexes are non-electrolytic in nature. From the magnetic moments the complexes are paramagnetic except
Zn metal ion complexes have octahedral geometry with coordination number eight. The thermal behavior of
these complexes shows that, the hydrated complexes have loses two water molecules and immediately followed
by decomposition of the anions and ligand molecules in the second and third stage. The Schiff bases and metal
complexes show good activity against some bacteria. The antimicrobial results indicate that, the metal
complexes have better antimicrobial activity as compared to the prepared Schiff base.
Synthesis, Spectroscopic study & Biological Activity Of Some Organotin(Iv) De...IOSR Journals
Some di-and triorganotin(IV) derivatives of (2E)-N-methyl-(2
oxo1,2diphenylethylidne)hydrazinecarbothioamide synthesised by the reactions of the corresponding di and
triorganotin(IV) chlorides with the sodium salt of (2E)-N-methyl-(2-
oxo1,2diphenylethylidne)hydrazinecarbothioamide in different molar ratios. These derivatives have been
characterized by elemental analyses ,molecular weights, conductivity measurements and spectral(IR, 1H, 13C
and 119 Sn NMR) studies.
This document describes the synthesis, spectral characterization, and biological screening of transition metal complexes of the ligand 2-(5-mercapto-1,3,4-oxadiazol-2-yl)phenol. A series of complexes were prepared using Cu(II), Co(II), Ni(II), and Zn(II) and characterized using analytical data, magnetic susceptibility, IR, UV-Vis, 1H NMR, 13C NMR, EPR, and other techniques. Spectral data suggest an octahedral geometry around the metal ion. Biological screening showed the complexes have antibacterial, antifungal, and DNA cleavage activities.
Its related to Study of gene metal-ligand stability constant of cefadroxil with cu2+ metal ion ph metrically at 0.1 m ionic strength. Also describe another Parameters.
1. The document describes the synthesis and characterization of novel Schiff base ligands and their transition metal complexes.
2. Several heterocyclic aldehydes and aniline derivatives were synthesized and used to prepare Schiff bases. These include Schiff bases derived from 4-methylumbelliferone and N-methylpropane-1,3-diamine.
3. The Schiff bases were characterized using analytical techniques like NMR, MS and IR spectroscopy. They were then used to prepare transition metal complexes which will be explored for potential biological activities.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
Max mosley f1 rules-livery numbers - pdfMax Mosley
The FIA is changing the requirements for obtaining a Super Licence needed to compete in Formula One racing. Beginning in 2016, drivers will need to accumulate 40 points over three years based on their results in other motorsport series. They will also need a valid road license, pass a test on F1 regulations, and complete 300km in a recent F1 car. The document provides details on the point allocation system and other rule modifications.
This document summarizes key aspects of safe harbor laws, which are designed to protect domestic minor victims of sex trafficking. The main points are:
1) Safe harbor laws require that sexually exploited minors be provided specialized services instead of facing criminal charges. They also impose higher penalties on buyers and traffickers.
2) Key elements of safe harbor laws include protecting minors, providing them services, and increasing penalties for traffickers/buyers. Training for law enforcement is also important.
3) Important court cases and studies show that arresting and detaining minor victims is re-traumatizing and ineffective, while specialized programs have improved victims' well-being. Safe harbor laws aim to
Welfare24 n.4/2015 - Notizie Assidai - Il fondo Sanitario per il tuo benesser...Assidai
Far conoscere i fondi di assistenza sanitaria:
ecco la prossima grande sfida di Assidai.
Da un’indagine Ipsos emerge che i responsabili HR non hanno una visione approfondita del tema
This document provides an overview and summary of the 2015 World Anti-Doping Code. It explains that the Code sets the global standards for anti-doping work in sport and aims to protect the rights of clean athletes. It applies to national- and international-level athletes. The document reviews key aspects of the Code including definitions of doping, prohibited substances and methods, therapeutic use exemptions, testing procedures, and consequences for anti-doping rule violations. It also outlines the roles and responsibilities of athletes, coaches and support personnel in regards to anti-doping.
YuanGuan Plastic & Mold is a one-stop solution provider for double-color and over-mold plastics located in South China. The company has 12,000 square meters of facilities, 300 employees, and is ISO 9001 certified. It offers molding and injection services from initial design to final delivery. Key aspects of the company include its emphasis on quality control, an in-house R&D department with 45 personnel and molding/injection capacities of 80 sets and 180,000 pieces per day respectively. The presentation highlights the company's structure, management systems, and strengths as a supplier for industries including telecommunications, electronics, and consumer goods.
The Spanish Grand Prix takes place at the Circuit de Barcelona-Catalunya in Spain. The track is 4.655 kilometers long and features several notable turns. Turn 1 is the main overtaking point as it is a braking zone at the end of a long straight. Turn 9, Campsa Corner, is a very fast right-hander that is completely blind to drivers, making it difficult. The track layout was redesigned by Hermann Tilke to lower speeds onto the pit straight and increase overtaking opportunities.
This short document provides photos from various photographers and suggests that the reader may be inspired to create their own Haiku Deck presentation on SlideShare. It includes photos taken by zetson, NEC Corporation of America, hcplebranch, and Nanagyei and encourages the viewer to get started making their own presentation.
This document discusses how crowdsourcing and open data can enhance data collection, policymaking, and monitoring related to population aging. It provides examples of how Scotland has leveraged high-quality linked health data to analyze spending on institutional versus community-based care for those aged 65+, examine costs associated with dementia, and perform cohort-specific analysis. The document argues that governments are increasingly harnessing crowdsourced data and suggests crowdsourcing could also enhance data and policy regarding aging populations.
The document discusses claims that were made about how legalized abortion would reduce crime rates and social problems. It summarizes evidence showing these claims were based on unsupported assumptions and did not account for abortion actually increasing out-of-wedlock births and unstable family structures, which are linked to higher crime rates. While abortion may have culled some high-risk demographics, this was more than offset by its unintended consequences of weakening social norms against premarital sex and non-marital childbearing.
The document provides an overview of cloud computing concepts and services. It discusses the history and evolution of cloud computing. The key cloud services discussed are Software as a Service (SaaS), Platform as a Service (PaaS), and Infrastructure as a Service (IaaS). Virtualization is described as a foundational technology for cloud computing. The document also examines the pros and cons of cloud computing and its future directions.
The document is an agenda for the 2015 Performance Challenge event hosted by Performance Films. It will include business development seminars, product demonstrations, and competitions. Representatives from various companies will be in attendance. The agenda outlines the schedule over multiple days/bays which include sessions on digital marketing, sales techniques, new products, and tournaments for automotive and architectural window tinting. It encourages participants to optimize their experience at the event to help grow their businesses.
The document discusses claims that were made about how legalized abortion would reduce crime rates and social problems. It summarizes evidence showing these claims were based on unsupported assumptions and did not account for abortion actually increasing out-of-wedlock births and unstable family structures, which are linked to higher crime rates. While abortion may have culled some high-risk demographics, this was more than offset by its unintended consequences of weakening social norms against premarital sex and non-marital childbearing.
IP-X8 SGS test report for YG water-proof iPhone 6 case.PDFYG Plastic
This 7-page test report summarizes waterproof and drop tests performed on a waterproof iPhone 6 case submitted by Dongguan Yuanguan Plastic & Mold Co., Ltd. Two tests were conducted: an IPX8 waterproof test by submerging the case 3 meters deep for 3 hours with no water ingress, and a drop test from 3 meters onto concrete with the case showing no visible damage after 10 drops. Both tests were passed based on the client's requirements. The report provides detailed test methods, conditions, results and photos documenting the testing process and outcomes.
Anthranillic acid and tributylphosphine4652 6725-1-pbTaghreed Al-Noor
Mixed ligand complexes of bivalent metal ions, viz; Co(II), Ni(II), Cu(II) and Zn(II) of the
composition [M(A)2((PBu3)2]in(1:2:2)(M:A:(PBu3). molar ratio, (where A- Anthranilate ion
,(PBu3)= tributylphosphine. M= Co(II),Ni(II),Cu(II) and Zn(II).
The prepared complexes were characterized using flame atomic absorption, by FT-IR,
UV/visible spectra methods as well as magnetic susceptibility and conductivity measurements. The
metal complexes were tested in vitro against three types of pathogenic bacteria microorganisms:
(Staphylococcus, Klebsiella SPP .and Bacillas)to assess their antimicrobial properties. Results. The
study shows that all complexes have octahedral geometry; in addition, it has high activity against
tested bacteria. Based on the reported results, it may be concluded that.The results showed that the
deprotonated ligand(nthranilc acid ) to anthranilate ion (A-) by using (KOH) coordinated to metal
ions as bidentate ligand through the oxygen atom of the carboxylate group (−COO−), and the
nitrogen atom of the amine group (-NH2), where the Tributylphosphine coordinated as a
This document summarizes the synthesis and characterization of lanthanide complexes with the drug cloxacillin. Cloxacillin is an antibiotic drug that is commonly used to treat bacterial infections. Seven lanthanide complexes of the form [Ln(Clox)2(H2O)2]Cl where Ln = La(III), Pr(III), Nd(III), Sm(III), Dy(III), Ho(III) and Er(III) were synthesized. The complexes were characterized using elemental analysis, infrared spectroscopy, electronic spectroscopy, magnetic susceptibility measurements, and thermal analysis. Elemental analysis showed a 1:2 metal to ligand ratio in the complexes. Infrared spectroscopy indicated that cloxacillin binds in
Synthesis and Characterization of Thermal Analysis of La (Ii) Macrocyclic Com...inventionjournals
The macrocyclic complex compounds of La(II) containing a ligand having tetraoxotetrahydrazin moity are synthesized by template condensation of malonodihydrazide (C3H8N4O2) with different aldehydes. The complexes are characterized on the basis of elemental analysis, UV-visible & IR spectroscopy, magnetic moment and conductance measurement and other physical properties.Antibacterial activity of the derived complex compounds, as well as already used standard compound kanamycin, was tested on fourteen pathogenic bacteria. Given results were then compared to the efficacy of the Antibacterial activity of standard compound kanamycin used for control of these pathogenic bacteria.
A STUDY TO EVALUATE THE IN VITRO ANTIMICROBIAL ACTIVITY AND ANTIANDROGENIC E...Dr. Pradeep mitharwal
The present paper deals with synthesis and characterization
of some new chromium (III) Schiff base complexes using microwave irradiation
technique as well as conventional heating. The S∩N donor benzothiazolines, 1-
(2-furanyl) ethanone benzothiazoline (Bzt1N
∩
SH), 1-(2-thienyl) ethanone
benzothiazoline (Bzt2N
∩
SH) and 1-(2-pyridyl) ethanone benzothiazoline
(Bzt3N
∩
SH) were prepared by the condensation of ortho-aminothiophenol with
respective ketones in ethanol.
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Visible Spectrophotometric Determination of Gemigliptin Using Charge Transfer...Ratnakaram Venkata Nadh
A visible spectrophotometric method was developed and validated for the determination of gemigliptin present in bulk drug and tablet formulation. It involves an indirect method of charge transfer complex formation in presence of NBS, metol and suphanilic acid. Gemigliptin was subjected to oxidation with excess amount of oxidant (NBS) and the unconsumed NBS oxidizes metol to give p-N-methylbenzoquinone monoamine (PNMM) which in turn forms a charge transfer complex with sulphanilic acid. Then validated the above developed method as per the current ICH guidelines. An excellent correlation coefficient (> 0.999) was found for the obtained regression equation
(y = –0.0302x + 0.928) in the range of 2.0–30.0 μg mL-1. The method was found to be simple and rapid because it does not involve any solvent extraction. The recovery levels of the drug were in the range 99.92 – 100.08.
Visible Spectrophotometric Determination of Gemigliptin Using Charge Transfer...Ratnakaram Venkata Nadh
A visible spectrophotometric method was developed and validated for the determination of gemigliptin present in bulk drug and tablet formulation. It involves an indirect method of charge transfer complex formation in presence of NBS, metol and suphanilic acid. Gemigliptin was subjected to oxidation with excess amount of oxidant (NBS) and the unconsumed NBS oxidizes metol to give p-N-methylbenzoquinone monoamine (PNMM) which in turn forms a charge transfer complex with sulphanilic acid. Then validated the above developed method as per the current ICH guidelines. An excellent correlation coefficient (> 0.999) was found for the obtained regression equation
(y = –0.0302x + 0.928) in the range of 2.0–30.0 μg mL-1. The method was found to be simple and rapid because it does not involve any solvent extraction. The recovery levels of the drug were in the range 99.92 – 100.08.
A new and efficient synthesis of 1 (4-subtitued phenyl)-3-(1-(6-(substitued-2...Alexander Decker
This document describes a new efficient method for the synthesis of 1-(4-Subtitued phenyl)-3-(1-(6-(Substitued-2-yl)pyrimidin-4-yl)piperidin-4-yl)ureas. Tert-butyl (1-(6-chloropyrimidin-4-yl)piperidin-4-yl)carbamate is coupled with various arylboronic acids using Suzuki coupling to yield intermediates. These intermediates are then deprotected and coupled with various aryl isocyanates using triethylamine to yield the final urea products in good yields. In total, twelve new 4,6-disubstituted
Coordination modes of a new ligand derived from pyrazoline with cr(iii), mn(i...Alexander Decker
This document summarizes a study that synthesized and characterized coordination complexes of Cr(III), Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) metal ions with a new ligand derived from pyrazoline. The complexes were analyzed using various techniques including elemental analysis, infrared spectroscopy, NMR spectroscopy, magnetic susceptibility measurements, and electronic spectroscopy. The data indicated the ligand behaves as a neutral bidentate toward the metal ions. The biological activities of the ligand and its complexes were screened against bacteria and fungi, with some complexes showing higher antimicrobial activity than the free ligand.
Synthesis, Characterization and Antibacterial Activity of New Complexes of So...IOSR Journals
Complexes of some lanthanide picrates (Ln3+ = Pr3+, Nd3+ and Dy3+) with benzo-18-crown-6 and 221-cryptand were synthesized and characterized by elemental analysis, FTIR, and UV-Visible. Spectrophotometric methods, thermal analysis (TGA & DTG), melting point, magnetic susceptibility and molar conductance. Also an in-vitro study on gram positive (Staphylococcus aureus) and gram negative bacteria (Escherichia coli, Salmonella and pseudomonas aeruginosa) was performed and the results were compared to those of the broad spectrum antibiotic Chloramphinicol. The benzo-18-crown-6 complexes have the general formula of [Ln.L.(Pic)2]Pic.nH2O , where; (Ln3+ = Pr3+, Nd3+, and Dy3+) , (L = Benzo-18-crown-6) , (Pic = Picrate anion) , (n = 1-2). In these complexes two picrate anions are coordinated to the metal ion through the phenolic oxygen and oxygen of the ortho nitro group, thus, the metal ions in these complexes have a coordination number of (10). The complexes of 221-cryptand have the general formula of [Ln.L.(Pic)]Pic2.nH2O where; (Ln3+ = Pr3+, Nd3+, and Dy3+), (L = 221-cryptand), (Pic = Picrate anion), (n = 1,2 or 7). In these complexes one picrate anion is coordinated to the metal ion, also through the phenolic oxygen and the oxygen from the ortho nitro group, thus the metal ions in the cryptand complexes have a coordination number of (9).
This document summarizes a study that measured the electrical conductivity of transition metal complexes containing manganese, cobalt, nickel, and copper ions coordinated with the ligand 2,2'-bipyridyl in different solvents at 298.16K. The conductivity was analyzed using the Lee-Wheaton conductivity equation. The results were used to calculate conductivity parameters including ionic conductivity, association constant, and average distance between ions. The conductivity parameters were found to depend on the solvent used.
SYNTHESIS AND CHARACTERIZATION OF THERMAL ANALYSIS OF La (II) MACROCYCLIC COM...inventionjournals
This document summarizes the synthesis and characterization of lanthanum (II) macrocyclic complexes and their biological activity. Lanthanum complexes were synthesized by reacting malonodihydrazide with lanthanum perchlorate hexahydrate in the presence of various aldehydes. The complexes were characterized using elemental analysis, infrared spectroscopy, UV-visible spectroscopy, magnetic moment measurements, and thermal analysis. The complexes exhibited antibacterial activity against several pathogenic bacteria.
Antibacterial Application of Novel Mixed-Ligand Dithiocarbamate Complexes of ...IOSR Journals
The document summarizes the synthesis and characterization of nine novel mixed-ligand dithiocarbamate complexes of nickel(II) and their antibacterial properties. The complexes were prepared by reacting nickel chloride with salicylaldehyde and aryl dithiocarbamates. They were characterized using various analytical techniques and had general formula [Ni(Sal)(Rdtc)]. The complexes exhibited broad-spectrum antibacterial activity against Escherichia coli, Staphylococcus aureus, Klebsiella oxytoca and Pseudomonas aureginosa based on agar diffusion tests, suggesting their potential as broad-spectrum antibacterial agents.
1. A new Schiff base ligand was synthesized by condensing amoxicillin and 4-(dimethylamino)benzaldehyde. Mixed ligand complexes were synthesized from reactions of the Schiff base ligand with metal salts such as Fe(II), Co(II), Ni(II), Cu(II), and Zn(II) along with nicotinamide.
2. The complexes were characterized using various techniques such as elemental analysis, FT-IR, UV-Vis, magnetic susceptibility measurements, and evaluating their conductivities. The data indicated the complexes had octahedral geometries and were non-electrolytes.
3. The antimicrobial activities of the complexes were evaluated against various bacteria and found to have
1. A new Schiff base ligand was synthesized from amoxicillin and 4-(dimethylamino)benzaldehyde. Mixed ligand complexes were synthesized from reactions of the ligand with Fe(II), Co(II), Ni(II), Cu(II), and Zn(II) and nicotinamide in a 1:1:2 ratio.
2. The ligand and complexes were characterized using various spectroscopic and analytical techniques. Octahedral geometries were suggested for the complexes.
3. The antimicrobial activities of the complexes were evaluated against various bacterial species and found to have enhanced activity compared to the uncomplexed ligand.
1) The document describes the synthesis and biological activity of new derivatives of 6-chloro-5-((4chlorophenyl)diazenyl)pyrimidine-2,4-diamine and 4-chloro-6-methoxy-N,N-dimethylpyrimidin-2-amine.
2) Various pyrimidine derivatives were synthesized using Suzuki cross-coupling reactions with arylboronic acids. The synthesized compounds were screened for antimicrobial activity.
3) Against gram-positive bacteria, 1/10 isolates of S. aureus and 3/10 isolates of S. saprophyticus were sensitive to one compound, while 1/10 isolates of each were sensitive to another
Design, Synthesis and Structural Inspection of Some Novel Di- And Tri-Azometh...CrimsonPublishersACSR
The document describes the design, synthesis, and characterization of novel di- and tri-azomethene compounds as chemosensors for detecting various metal ions. Two ligands, DAPH and NBA, were synthesized via condensation reactions and characterized using techniques such as FT-IR, NMR, and elemental analysis. The ligands were tested for their ability to detect metal ions like Cr3+, Fe2+, Co2+, Ni2+, Cu2+, Zn2+, Mn2+, VO2+, and Pd2+ through changes in UV-visible absorption spectra upon complexation. DAPH showed color changes with different metals, while NBA showed color changes with Fe2+ and Pd2+.
This document describes the synthesis of novel spirooxindole derivatives via a three-component 1,3-dipolar cycloaddition reaction. Various spirooxindole-spiropiperidinone-pyrrolidine and spirooxindole-spiropiperidinone-pyrrolizine derivatives were synthesized in good yields from isatin, sarcosine or L-proline, and Knoevenagel adducts under optimized reaction conditions. The antimicrobial activities of the synthesized compounds were evaluated, with some compounds exhibiting excellent activity against bacteria and fungi, comparable or superior to standard antimicrobial drugs.
This document describes the synthesis and characterization of 4-(4-N,N-dimethylaminobenzylideneamino)phenyltellurium tribromide. The compound was synthesized by reacting 4-(4-N,N-dimethylaminobenzylideamino)phenyl mercuric chloride with tellurium tetrabromide. It was characterized using various techniques such as elemental analysis, FTIR, UV-Visible, 1H and 13C- NMR spectroscopies, X-Ray diffraction and optical measurements. Thin films of the compound were deposited and their optical properties like refractive index, extinction coefficient and optical energy gap were determined from transmittance measurements in the wavelength range of 190-900
This document discusses the isolation of Bacillus thuringiensis from soil in Basra, Iraq and its ability to biosorb heavy metals like cadmium and lead. B. thuringiensis showed resistance to high concentrations of lead and cadmium. Experiments examined the effect of metal concentration and contact time on biosorption. Fourier transform infrared spectroscopy and X-ray powder diffraction analysis were used to identify functional groups on the bacterial surface. The bacterium was able to effectively biosorb cadmium and lead from solutions, demonstrating its potential for remediating environments contaminated with heavy metals.
Shanghai ranking's global ranking of academic subjects 2020 chemistry convertedTaghreed Al-Noor
Shanghai Ranking's Global Ranking of Academic Subjects 2020 – Chemistry
http://www.shanghairanking.com/Shanghairanking-Subject-Rankings/chemistry.html
2020 تصنيف شنغهاي للجامعات حسب الموضوع – الكيمياء
Shanghai Ranking's Global Ranking of Academic Subjects 2020 Chemistry
prof .Taghreed H Al-Noor أ. د تغريد هاشم النور
جامعة بغداد University of Baghdad
that causes COVID-19 is called SARS-CoV
2020 - www.compoundchem.com @
prof .Taghreed H Al-Noor أ.د تغريد هاشم النور
University of Baghdad,Chair ACS Iraq chapter
Virtual International Scientific Conference Curriculum The Role Of Higher Education And Scientific Research Formations And National Institutions In Confronting The Corona Pandemic Forensic DNA Center for Research and Training / Al-Nahrain University .American Chemical Society ACS and its role in confronting Corona pandemic )
Prof. Taghreed Hashim Al.Noor Chairman chapter Iraq of the American Chemical Society
This document lists information about 33 journals that have been victims of website hijacking. It provides the original URL for each journal's website as well as the hijacked URL. Many of the hijacked URLs have been used to publish fake articles or divert traffic from the legitimate journal websites. This document serves to identify journals that have had their online presence compromised by fraudulent actors.
Asian Journal of Biochemistry is an International peer-reviewed journal dedicated to publish the results of original research in form of original articles, reviews and short communications. Scope of the journal includes: Structure, function and regulation of biologically active molecules; gene structure and expression; biochemical mechanisms; protein biosynthesis; protein folding; membrane structure-function relationships; bioenergetics and immunochemistry. Asian Journal of Biochemistry now accepting new submissions. Submit your next paper via online submission system.
ACS Iraq chapter
Supported
45Mins5th International Turkic World
Conference on Chemical Sciences and
Technologies (ITWCCST 2019)” which will take place in Sakarya,
Turkey between 25-29 October 2019.
1SecondScientific Committee
Taghreed H AL-NOOR
University of Baghdad, Iraq chair ACS IRAQ member in
http://2019.itwccst.org/?page_id=149
Five steps to creating a citation overview in scopus, Taghreed Al-NoorTaghreed Al-Noor
The document provides instructions for creating a citation overview in Scopus in 5 steps: 1) narrow search results to under 2,000 items, 2) select documents to include, 3) view the citation information table including citations from the current and previous 4 years, 4) modify the table display, and 5) analyze citation patterns and trends. The overview can help identify influential studies, compare journals, and review author performance.
Catalysis, chemical engineering 2019 taghreed al noorTaghreed Al-Noor
Synthesis, spectroscopic characterization, biological Activity and dye on
cotton fabric of mixed ligand metal complexes derived From curcumin and Lphenyl alanine, schiff Base and anthranilic acid
DFT, cytotoxicity and molecular docking studies of (E)-2((2- hydroxybenzylide...Taghreed Al-Noor
Kathmandu Symposia on Advanced Materials (KaSAM)-2018; October 26-29, 2018, Kathmandu, Nepal
DFT, cytotoxicity and molecular docking studies of (E)-2((2-
hydroxybenzylidene) amino-3-mercaptopropanoic acid and its Co(II),
Ni(II) and Cu(II) complexes
M.M. El-ajaily1*, S.S. Mahmoud2, R.N. El-daghare1, A.K. Sarangi3, R.K. Mohapatra3* and T.H.
Al-Noor4
1Chemistry Department, Faculty of Science, Benghazi University, Benghazi, Libya
2Chemistry department, Faculty of Science, Cairo University, Giza, Egypt
3Department of Chemistry, Government College of Engineering, Keonjhar, Odisha, India
4Chemistry Department, Ibn-Al-Haithem College of Education for Pure Science, Baghdad University,
Baghdad, Iraq
*E-mail: ranjank_mohapatra@yahoo.com
The cytotoxicity studies of a Schiff base; (E)-2((2-hydroxybenzylidene)amino-3-mercaptopropanoic acid
(HL) derived from the condensation of 2-hydroxybenzaldehyde and L-cysteine and its Co(II), Ni(II)
and Cu(II) complexes have been reported against four cancer cell lines. The evaluation of the growth
inhibitory on human cancer cells is studied for the chelates against HCT-116, MCF-7, HFB-4,
HepG-2 cell lines. The obtained results (Fig. 1) revealed that the compounds are active against human
hepatocellular carcinoma cell line (HepG-2).
Scimago journal & country rank taghreed al noorTaghreed Al-Noor
Scimago Journal & Country Rank
ترتيب الدول من ناحية نشر الباحثين في المجلات العالمية المصنفة و
H index جودة البحوث من خلال عدد الاقتباسات
حسب موقع
)SJR (Scimago Journal Rank الترتيب خاص بسنة 201
ACS GCCE Chemical Society ACS GCCE Chemical Society ACS GCCE Chemical Society ACS GCCE Chemical Society ACS GCCE Chemical Society ACS GCCE Chemical Society ACS GCCE Chemical Society ACS GCCE Chemical Society Capacity Building Workshop Capacity Building Workshop Capacity Building Workshop Capacity Building Workshop Capacity Building Workshop Capacity Building Workshop Capacity Building Workshop 14 -18 October, 2018 October, 2018October, 2018 October, 2018
•
3rd Internatioanl Medical Congress, will be hold in Kerbala, Iraq in 14-15 De...Taghreed Al-Noor
3rd Internatioanl Medical Congress, will be hold in Kerbala, Iraq in 14-15 December 2018 by Nab'a Al-Hayat Foundation for Medical Sciences and Health Care, and in collaboration with (University of Kerbala, University of Kufa, Directory of Research -Ministry of Health Oman, University of Sussex, University of Komar, University of Diyala, University of Qaddisya, University of Al-Anbar, University of Al-Mustansariya and Helal Iran Pharmaceutical Complex.
Facial Acne Therapy by Using Pumpkin Seed Oil with Its Physicochemical Proper...Taghreed Al-Noor
The herbal remedy individually or in combination with standard medicines has been used in diverse medical treatises for the cure of different diseases. Pumpkin seed oil is one of the recognized edible oil and has substantial medicinal properties due to the presence of unique natural edible substances. Inflammation is an adaptive response that is triggered by noxious stimuli and conditions, which involves interactions amongst many cell types and mediators, and underlies many pathological processes. Unsaturated fatty acids (UFAs) can influence inflammation through a variety of mechanisms, and have been indicated as alternative anti-inflammatory agents to treat several inflammatory skin disorders. Pumpkin seed oil is rich in (UFAs), that its topical anti-inflammatory properties have been investigated. For that reason, the goal of this article was to evaluate the effects of pumpkin seed oil on acute and chronic cutaneous inflammation experimental models. The extracted pumpkin seed oil had an acceptable initial quality, when it was extracted using soxhlet extraction method and was characterized using standard methods .The physicochemical parameters of purified oil were determined. The boiling point of pumpkin seed oil was (158.90 oC) that equal to the values obtained in literature for some oil seeds, but lower than the boiling point of the oils studied, plus the melting point of pumpkin seed oil was (15.39 oC) that lead to a characteristic in cold cream manufacture. The iodine value was (104 ± 0.03 mg of KOH/g) of oil, indicated a high degree of unsaturation. The saponification value was (181± 3.2 mg KOH/g), this value indicated the pumpkin seed oil had fatty acids with higher number of carbon atoms. As a final point, the acid value was
Bidentate Schiff base ligand 3-(3,4-Dihydroxy-phenyl)-2-[(4-dimethylamino-benzylidene)-amino]-2-methyl-propionic acid was prepared and characterized by spectroscopic techniques studies and elemental analysis. The Cd(II), Ni(II), Cu(II), Co(II), Cr(III),and Fe(III) of mixed-ligand complexes were structural explicate through moler conductance , [FT-IR, UV-Vis & AAS], chloride contents, , and magnetic susceptibility measurements. Octahedral geometries have been suggested for all complexes. The Schiff base and its complexes were tested against various bacterial species, two of {gram(G+) and gram(G-)} were shown weak to good activity against all bacteria.
How to Manage Your Lost Opportunities in Odoo 17 CRMCeline George
Odoo 17 CRM allows us to track why we lose sales opportunities with "Lost Reasons." This helps analyze our sales process and identify areas for improvement. Here's how to configure lost reasons in Odoo 17 CRM
A workshop hosted by the South African Journal of Science aimed at postgraduate students and early career researchers with little or no experience in writing and publishing journal articles.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
বাংলাদেশের অর্থনৈতিক সমীক্ষা ২০২৪ [Bangladesh Economic Review 2024 Bangla.pdf] কম্পিউটার , ট্যাব ও স্মার্ট ফোন ভার্সন সহ সম্পূর্ণ বাংলা ই-বুক বা pdf বই " সুচিপত্র ...বুকমার্ক মেনু 🔖 ও হাইপার লিংক মেনু 📝👆 যুক্ত ..
আমাদের সবার জন্য খুব খুব গুরুত্বপূর্ণ একটি বই ..বিসিএস, ব্যাংক, ইউনিভার্সিটি ভর্তি ও যে কোন প্রতিযোগিতা মূলক পরীক্ষার জন্য এর খুব ইম্পরট্যান্ট একটি বিষয় ...তাছাড়া বাংলাদেশের সাম্প্রতিক যে কোন ডাটা বা তথ্য এই বইতে পাবেন ...
তাই একজন নাগরিক হিসাবে এই তথ্য গুলো আপনার জানা প্রয়োজন ...।
বিসিএস ও ব্যাংক এর লিখিত পরীক্ষা ...+এছাড়া মাধ্যমিক ও উচ্চমাধ্যমিকের স্টুডেন্টদের জন্য অনেক কাজে আসবে ...
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...PECB
Denis is a dynamic and results-driven Chief Information Officer (CIO) with a distinguished career spanning information systems analysis and technical project management. With a proven track record of spearheading the design and delivery of cutting-edge Information Management solutions, he has consistently elevated business operations, streamlined reporting functions, and maximized process efficiency.
Certified as an ISO/IEC 27001: Information Security Management Systems (ISMS) Lead Implementer, Data Protection Officer, and Cyber Risks Analyst, Denis brings a heightened focus on data security, privacy, and cyber resilience to every endeavor.
His expertise extends across a diverse spectrum of reporting, database, and web development applications, underpinned by an exceptional grasp of data storage and virtualization technologies. His proficiency in application testing, database administration, and data cleansing ensures seamless execution of complex projects.
What sets Denis apart is his comprehensive understanding of Business and Systems Analysis technologies, honed through involvement in all phases of the Software Development Lifecycle (SDLC). From meticulous requirements gathering to precise analysis, innovative design, rigorous development, thorough testing, and successful implementation, he has consistently delivered exceptional results.
Throughout his career, he has taken on multifaceted roles, from leading technical project management teams to owning solutions that drive operational excellence. His conscientious and proactive approach is unwavering, whether he is working independently or collaboratively within a team. His ability to connect with colleagues on a personal level underscores his commitment to fostering a harmonious and productive workplace environment.
Date: May 29, 2024
Tags: Information Security, ISO/IEC 27001, ISO/IEC 42001, Artificial Intelligence, GDPR
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it describes the bony anatomy including the femoral head , acetabulum, labrum . also discusses the capsule , ligaments . muscle that act on the hip joint and the range of motion are outlined. factors affecting hip joint stability and weight transmission through the joint are summarized.
How to Build a Module in Odoo 17 Using the Scaffold MethodCeline George
Odoo provides an option for creating a module by using a single line command. By using this command the user can make a whole structure of a module. It is very easy for a beginner to make a module. There is no need to make each file manually. This slide will show how to create a module using the scaffold method.
Executive Directors Chat Leveraging AI for Diversity, Equity, and InclusionTechSoup
Let’s explore the intersection of technology and equity in the final session of our DEI series. Discover how AI tools, like ChatGPT, can be used to support and enhance your nonprofit's DEI initiatives. Participants will gain insights into practical AI applications and get tips for leveraging technology to advance their DEI goals.
Exploiting Artificial Intelligence for Empowering Researchers and Faculty, In...Dr. Vinod Kumar Kanvaria
Exploiting Artificial Intelligence for Empowering Researchers and Faculty,
International FDP on Fundamentals of Research in Social Sciences
at Integral University, Lucknow, 06.06.2024
By Dr. Vinod Kumar Kanvaria
A review of the growth of the Israel Genealogy Research Association Database Collection for the last 12 months. Our collection is now passed the 3 million mark and still growing. See which archives have contributed the most. See the different types of records we have, and which years have had records added. You can also see what we have for the future.
Main Java[All of the Base Concepts}.docxadhitya5119
This is part 1 of my Java Learning Journey. This Contains Custom methods, classes, constructors, packages, multithreading , try- catch block, finally block and more.
2. 10-3
M, using disc sensitivity test. This method involves the
exposure of the zone of inhibition toward the diffusion of
micro- organism on agar plate. The plates were incubated for
24hrs at 37Co
.
Preparation of Metal Complexes
A general method was used for the synthesis of the metal
complexes. An aqueous solution of the metal salts containing
0.118g, 0.118g, 0.085g and 0.068g (1mmole) of CoCl2.6H2O,
NiCl2.6H2O, CuCl2.2H2O and ZnCl2 respectively was added
gradually with stirring to ethanolic solution (0.203g,2mmol) of
4-aminoantipyrine (4-AAP) and (0.5ml,2mmole) of
tributylphosphine (PBu3) was added to the mixture in each
case by using stichiometric amount (1:2:2) Metal: 4-AAP:
PBu3 molar ratio. The mixture was refluxed with constant
stirring for an hour. The v product formed was filtered off , and
recrystillized from ethanol and dried at room temperature ,and
analyzedemploying standard method.
RESULTS AND DISCUSSION
The solid complexes were prepared by reaction of alcoholic
solution of the tow ligands with the aqueous solution of the
metal ions in a (M: (4-AAP): (PBu3) of (1:2:2). The metal
contents of these complexes were in good agreements with the
calculated values (Table 1) includes the physical properties.
The molar conductance of the complexes as (10-3
M) in DMSO
indicating their electrolytic nature ratio (1:2) (Geary, 1971), the
data were recorded in (Table 1).
The complexes are soluble in dimethyl form amide (DMF)
dimethyl sulfoxide (DMSO), while insoluble in water and
common solvents. The test for chloride ion with AgNO3
solution was positive indicating that chloride ion is out side
of coordination sphere. (Taghreed et al., 2013)
The UV/Visible spectra
The UV-Vis spectra data for the free ligands and all metal
complexes are listed in (Table 2). The UV-Vis spectrum of the
ligand 4-AAP shows two peaks at 235 nm and 283 nm assigned
to ( – *) and (n – *) electronic transitions respectively. The
electronic spectrum of tributylphosphine display absorption
peak at 297 nm due to ( – *) (Sonme and Sekerci, 2002;
Suzuki et al., 1999).
The UV/Visible spectra and Magnetic Measurements μeff
(μB) of the Mixed Ligand Complexes
The electronic spectra of the Cu(II), Ni(II),Co(II) and Zn(II)
mixed ligand complexes have been recorded as DMSO
solutions in the wavelength range 200-1100 nm.
[Co (4-AAP)2(PBu3)2]Cl2
The magnetic susceptibility measurement after diamagnetic
corrections Table (1) yielded a magnetic moment of 4.52 BM
which is close to that expected for an octahedral Co(II)
complexes. The (U.V-Vis) Co(II) d7
(Term 4
F) spectrum,
Table (3) exhibits four peaks, The first high intense peak at
(272 nm)due to ligand field. The peak at 355 nm assigned to
charge transfer. Other two peaks at 562 nm and 680 nm were
found to be caused by (d-d) electronic transition type
4
T1g(F)→4
T1g(P) and 4
T1g(F) → 4
T2g(F) respectively (Taghreed
et al., 2012).
[Ni (4-AAP)2(PBu3)2] Cl2
The magnetic moment Table (1) of the Ni(II) d8
(Term3
F)
complex is 2.77B.M, indicating the octahedral configuration of
this complex. The spectrum of Ni(II) complex appeared
absorption peak at 246 nm was related to ligand field.
Table 1. Physical properties of the ligand and it's complexes
Compounds M. wt Color M.P °C Yield% M% Λm (S.cm2
.mol-1
) in DMSO(10-3
M)
[Co (4-AAP)2(PBu3)2]Cl2
C46H80Cl2CoN6O2P2
941.0 brown 183 68 6.79
(5.83)
51.67
[Ni(4-AAP)2(PBu3)2]Cl2
C46H80Cl2CoN6O2P2
940.7 green 171 71 6.56
(5.95)
68.55
[Cu(4-AAP)2(PBu3)2]Cl2
C46H80Cl2CoN6O2P2
945.6 dark blue 194 67 7.32
(6.82)
72.41
[Zn(4-AAP)2(PBu3)2] Cl2
C46H80Cl2CoN6O2P2
947.4 pal yellow 155 73 7.42
(6.88)
77.32
m=Molar Conductivity, M.P = melting point
Table 2. UV-Vis, magnetic susceptibility and conductance measurements data
Compounds λmax (nm) Wave number (cm-1
) €max (L.mol-1
.cm-1
) Remarks µeff (B.M)
PBu3 297 33670 6095 → *
Ligand (4-AAP) 235
238
42553
35335
1191
746
→ *
n → *
[Co(4-AP)2(PBu3)2]Cl2 245
355
562
680
40816
28169
17793
14705
1530
226
183
91
L.F
C.T
4
T1g(F)→4
T1g(P)
4
T1g(F) →
4
T2g(F)
4.52
[Ni(4-AP)2(PBu3)2]Cl2 246
371
590
720
856
40650
26954
16949
13888
11682
1876
846
198
102
92
L.F
C.T
3
A2g(F) → 3
T1g(P)
3
A2g(F) → 3
T1g(F)
3
A2g(F) → 3
T2g(F)
2.77
[Cu(4-AP)2(PBu3)2]Cl2 273
392
632
36630
25510
15822
1361
845
205
L.F
C.T
2
Eg → 2
T2g
1.73
[Zn(4-AP)2(PBu3)2]Cl2 291
395
34364
25316
1103
741
C.T
C.T
Diama
15606 Taghreed.H.Al-Noor et al. Synthesis, spectral and antimicrobial activity of mixed ligand complexes of Co(II), Ni(II), Cu(II) and Zn(II) with
4-aminoantipyrine and tributylphosphine
3. The peak at 371 nm due to charge transfer, then other three
peaks at 590 nm, 720 nm and 856 nm were assigned to
electronic transition type
3
A2g(F) → 3
T1g(P),3
A2g(F) → 3
T1g(F) and 3
A2g(F) → 3
T2g(F)
respectively (Mohamed et al., 2006).
The electronic spectrum bands suggest octahedral geometry
around the Ni(II) ion
[Cu (4-AAP)2(PBu3)2] Cl2
The magnetic moment Table (1) of the Cu(II) d9 (Term 2D),
exhibits normal magnetic moments (1.73B.M.) which is in
agreement with data reported by several research workers
[5,13]. The spectrum of Cu(II) complex Table (2) gave
absorption peak at 273 nm due to ligand field, the peak at 392
nm attributed to charge transfer. The peak at 632 nm was
caused by electronic transition (Jebur et al., 2013) 2
Eg → 2
T2g.
[Zn(4-AAP)2(PBu3)2] Cl2
The spectrum of Zn(II) complex showed absorption peak at
291 nm due to ligand field, the Peak at 395 caused by charge
transfer. The absence of absorption peaks in the visible region
indicated no (d-d) electronic transition happened; this is a good
result for octahedral complex (Lever and A.B, 1968).
Fourier Transform Infrared (FTIR) Spectroscopy
In order to study the binding mode of the ligands
(4-aminoantipyrine) with the metal ions, a comparison was
made for the FT.IR spectra of the free ligand and those of the
prepared complexes and the data was tabulated in
(Tables 3 & 4). The IR spectrum of the ligand (4-AAP)
exhibited bands at 3429 cm-1
and 3323 cm-1
were assigned to
ν(NH2) stretching frequency (Masoud et al., 2003; Nakamot,
1996), on complexation a shifting with change in shape were
observed from these bands, while increasing in intensity were
noticed. The significant may be a result of coordination with
metal ion. The bands at 1676 cm-1
in the ligand spectrum
ascribed to ν(C=O), suffered a great change to lower frequency
were also observed on complexation with metal ion (Nair et al.,
2005; Kirkan and Gup, 2008).
Medium to strong absorption in the 1455- 1650 cm-1
region
often corresponds to aromatic ring vibrations. Finally the
region extending from 1597 to 1662 cm-1
corresponds to
stretching vibrations for C=C bonds. The new bands observed
at (576-430) cm-1
are tentatively assigned to ν(M-N),ν(M-O)
and ν(M-P) (Metal-Ligands) stretching bands (Thangadurai and
Natarajan, 2002; Boghaei and Mohebi, 2001; Osowole, 2008).
Primary ligand 4-aminoantipyrine act as bidentate ligands
when coordinated to metal ion [21] while the secondary ligand
(PBu3)binds the metal ion as mono dentate donors via
phosphor atom.According to the results obtained and spectral
analysis an octahedral structures have been suggested to these
complexes. (Scheme 1)
Antibacterial Activities studies
The biological activities of the ligands and their complexes
have also been tested against selected type of bacteria, (Table
5) show the deactivation capacity against the bacteria specimen
of the prepared compounds under study.
Table 3. Infrared spectrum data (wave number ύ) cm-1
for the ((PBu3))
Compound H-C-H Asymmetric & Symmetric Stretch C–H bend P-CH2 C–H rock
(PBu3) (2956-2872) vs 1462(m) 1413W 794,791
Table 4. Infrared spectra data (wave number ύ) cm-1
for the Compounds
Compounds υ(NH2) υ(C=O) υ(M-N) υ(M-O) υ(M-P)
Ligand (4-AAP) 3429 sh.
3323 sh.
1676 s. - - -
[Co(4-AAP)2(PBu3)2]Cl2 3353 br.
3257 br.
1606 s. 542 w. 503 w. 445 w.
[Ni(4-AAP)2(PBu3)2]Cl2 3373 br.
3244 br.
1637 sho. 474 w. 457 w. 435 w.
[Cu(4-AAP)2(PBu3)2]Cl2 3377 br.
3191 br.
1596 s. 503 w. 459 w. 443 w.
[Zn(4-AAP)2(PBu3)2]Cl2 3365 br.
3259 br.
1612 sh. 576 w. 559 w. 406 w.
sh =sharp, sho=shoulder, s = strong, w =weak, br = broad
Table 5. Diameters (mm) of deactivation of bacteria for the 4-aminoantipyrine and it'
s complexes
Compounds Staphylococcus aurous Escherichia coli Pseudomonas aeruginosa
Control DMSO 8 5 5
Ligand (PBu3) 16 12 15
Ligand(4-AAP) 25 17 10
[Co(4-AAP)2(PBu3)2]Cl2 31 15 15
[Ni(4-AAP)2(PBu3)2]Cl2 27 25 36
[Cu(4-AAP)2(PBu3)2]Cl2 13 32 20
[Zn(4-AAP)2(PBu3)2]Cl2 20 18 35
15607 International Journal of Current Research, Vol. 7, Issue, 05, pp.15605-15609, May, 2015
4. The diameter of the susceptibility zones were measured in mm
and the results are presented in Table (5) Scheme (1).
Compounds were considered as active when the (IZ) was
greater than 6 mm. Two ligands and their complexes
individually were found to be biologically active showing
various degrees of inhibitory effects on the growth of the tested
bacterial species (Sönmez et al., 2006). Mixed ligand metal
shown weak to good activity when compared to the Control.
Complexes have higher biological activities compared to the
free ligands and inhibition diameter was varied according to the
variation in the complex type and bacterial type. The increased
inhibition activity of the metal complexes can be explained on
the basis of Tweedy's chelation theory (Taghreed et al., 2013;
Tweedy, 1964; Taghreed et al., 2014). In metal complexes, on
chelation the polarity of the metal ion will be reduced to a
greater extent due to the overlap of the ligand orbital and
partial sharing of the positive charge of the metal ion with
donor groups. Further, it increases the delocalization of π-
electrons over thewhole chelate ring. The ring of (4-AAP)
moiety makes the complexes more lipophillic (Taghreed et al.,
2014).
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Scheme 1. Proposed Structure of [M (4-AAP)2(PBu3)2] (3D space- filling conformation, left)
Scheme 1. Chart of biological effects of the studied compounds
P(Bu)3
M
N
NH2N
O
CH3
CH3
Cl2
N
N
NH2
O
CH3
H3C
P(Bu)3
M+2
=Co,Ni,Cu,Zn
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15609 International Journal of Current Research, Vol. 7, Issue, 05, pp.15605-15609, May, 2015