5a reductase inhibitors a novel approach to treating acne
•Download as PPT, PDF•
1 like•615 views
The document discusses 5a reductase inhibitors and their potential use in treating acne. There are two types of 5a reductase isozymes, type 1 and type 2, which are involved in endogenous production of DHT. The document also explores other factors like insulin, IGF, SHBG, and herbal extracts that may help regulate hormones involved in acne pathogenesis. Two product formulations are highlighted that utilize plant extracts shown in research to help balance hormones: a serum containing green tea, saw palmetto, and other extracts, and a magnolia honey cream containing resveratrol.
Report
Share
Report
Share
Recommended
Achlorhydria e
Achlorhydria refers to states where the production of gastric acid in the stomach is absent or low and impairs protein digestion by inhibiting the activation of the enzyme pepsin, whose activation is dependent upon a low gastric pH.
As acid facilitates non-haem iron absorption, about 25% of achlorhydric patients develop iron-deficiency anaemia.
What the world health organisation WHO has to say on iron deficiency
Iron deficiency is a big problem internationally. The OptiFer® series of heme iron supplements has the potential for change worldwide
In defence of heme iron
Anybody can grasp and understand
that a very high consumption of meat, red and processed and what goes with it is generally not so healthy for many reasons and may lead to disease.
Too much iron in the body from for example syntethic iron supplements or excessive meat consumption is an equally bad thing with many potential, even fatal, consequences. This is also easy to grasp.
Heme iron and blood donation
Side effects often lead to the donors stopping taking the supplements, which in turn means that they can only donate blood perhaps once or twice a year instead of normally three times.
What can you claim about OptiFer® heme iron tablets
You cannot claim for a food supplement to diagnose, cure, treat, or prevent disease, such as anemia.
You can, however, treat iron deficiency, which affects many millions of people. In fact, in many countries, it is a huge problem.
Diabetes Ebook:Diabetes mellitus insights perspectives
This document summarizes insights and perspectives on the role of vitamins in preventing type 2 diabetes mellitus (T2DM) and its complications from a public health perspective. It discusses how T2DM is caused by impaired glucose tolerance and insulin resistance leading to inflammation. Certain vitamins like C, D and E are highlighted as having anti-inflammatory properties that could help reduce the risk of T2DM and its complications by attenuating inflammation. The document focuses on vitamin C in more detail, outlining its role in immune function and reducing oxidative stress and inflammation, suggesting it may help prevent T2DM. It reviews several epidemiological studies that have found inverse associations between vitamin C levels or intake and biomarkers of inflammation and T2DM risk.
Pros and cons of the regular supplements, What you need to know.
The OptiFer® products contain 100 % heme iron with no additives. This is the natural form that always has been an important part of the human diet and that we are adapted for. This is why the efficacy is so good and there are no adverse effecs.
Good sources for iron
Iron is essential for life. Daily intake should be at least 18 mg of iron to compensate for losses.
Heme iron is taken up at 20 – 40 % compared to non-heme 2 – 4 %, such as for example Ferrous Sulphate.
This means that one tablet of OptiFer® will give up to 7,2 mgs of absorbed iron. This is more than 150 mgs of non-heme iron will give.
Unpleasant side effects are dose-related and present in more than 30 % of therapies with non-heme iron.
In studies the tolerance of heme iron is virtually perfect.
Recommended
Achlorhydria e
Achlorhydria refers to states where the production of gastric acid in the stomach is absent or low and impairs protein digestion by inhibiting the activation of the enzyme pepsin, whose activation is dependent upon a low gastric pH.
As acid facilitates non-haem iron absorption, about 25% of achlorhydric patients develop iron-deficiency anaemia.
What the world health organisation WHO has to say on iron deficiency
Iron deficiency is a big problem internationally. The OptiFer® series of heme iron supplements has the potential for change worldwide
In defence of heme iron
Anybody can grasp and understand
that a very high consumption of meat, red and processed and what goes with it is generally not so healthy for many reasons and may lead to disease.
Too much iron in the body from for example syntethic iron supplements or excessive meat consumption is an equally bad thing with many potential, even fatal, consequences. This is also easy to grasp.
Heme iron and blood donation
Side effects often lead to the donors stopping taking the supplements, which in turn means that they can only donate blood perhaps once or twice a year instead of normally three times.
What can you claim about OptiFer® heme iron tablets
You cannot claim for a food supplement to diagnose, cure, treat, or prevent disease, such as anemia.
You can, however, treat iron deficiency, which affects many millions of people. In fact, in many countries, it is a huge problem.
Diabetes Ebook:Diabetes mellitus insights perspectives
This document summarizes insights and perspectives on the role of vitamins in preventing type 2 diabetes mellitus (T2DM) and its complications from a public health perspective. It discusses how T2DM is caused by impaired glucose tolerance and insulin resistance leading to inflammation. Certain vitamins like C, D and E are highlighted as having anti-inflammatory properties that could help reduce the risk of T2DM and its complications by attenuating inflammation. The document focuses on vitamin C in more detail, outlining its role in immune function and reducing oxidative stress and inflammation, suggesting it may help prevent T2DM. It reviews several epidemiological studies that have found inverse associations between vitamin C levels or intake and biomarkers of inflammation and T2DM risk.
Pros and cons of the regular supplements, What you need to know.
The OptiFer® products contain 100 % heme iron with no additives. This is the natural form that always has been an important part of the human diet and that we are adapted for. This is why the efficacy is so good and there are no adverse effecs.
Good sources for iron
Iron is essential for life. Daily intake should be at least 18 mg of iron to compensate for losses.
Heme iron is taken up at 20 – 40 % compared to non-heme 2 – 4 %, such as for example Ferrous Sulphate.
This means that one tablet of OptiFer® will give up to 7,2 mgs of absorbed iron. This is more than 150 mgs of non-heme iron will give.
Unpleasant side effects are dose-related and present in more than 30 % of therapies with non-heme iron.
In studies the tolerance of heme iron is virtually perfect.
Low dose vs high-dose
Why Low-dose is more efficient than High-dose when it comes to iron .A Heme-Iron tablet with a dose of 18 mg will yield up to 4 mgs for bodily needs, whereas a non-heme tablet of 100 mg will yield 2 mg. The rest is reactive and remains in the gut.
The body will absorb no more than it needs of Heme-Iron and the rest is completely inert – no stomach problems.
Accepted statements for OptiFer®
What is a food supplement?
A food or dietary supplement is a product intended for ingestion that contains a "dietary ingredient" intended to add further nutritional value to (supplement) the diet.
What can you claim for a food or dietary supplement ?
Some dietary supplements may help to ensure that you get an adequate dietary intake of essential nutrients; others may help you reduce your risk of disease.
Iron (New Dimension)
Things people don't consider often while consuming food containing iron would be be helpful for them to understand about acquiring maximum benefits of IRON.
What do we know about heme iron II
1) Heme iron is absorbed through a specific uptake process in the duodenal mucosal cells that is not affected by other dietary components like phytates or calcium.
2) Heme iron absorption is higher than non-heme iron absorption and will not be inhibited during conditions like treatment with proton pump inhibitors that decrease stomach acid and inhibit non-heme iron absorption.
3) Heme iron supplements are better tolerated than non-heme iron supplements and have a lower therapy failure rate due to side effects, allowing for improved anemia treatment and substantial savings.
About heme iron
There are two types of iron in the diet: heme iron found naturally in meat which is efficiently absorbed by the body, and non-heme iron found in plants which must be broken down before absorption and often causes gastrointestinal side effects. Heme iron supplements containing bovine hemoglobin provide a natural form of iron that is easily absorbed without side effects, unlike synthetic non-heme iron supplements which are poorly absorbed and commonly cause issues. A Swedish company produces heme iron supplements that effectively treat iron deficiency without the problems of existing non-heme supplements.
DHEA
DHEA Transcription:
DHEA (dehydroepiandrosterone) is a steroid hormone that is produced from pregnenolone in the adrenal cortex, gonads, nervous system and brain.
About 90% of DHEA is produced in the adrenal glands.
DHEA is the precursor to:
Progesterone
Testosterone
Estrogen
Around the age of 40 most people start producing inadequate levels of DHEA.
DHEA is a base for the sex hormones, and it also helps break down fats and cholesterol.
DHEA’s properties produce weak androgenic activity and have reported anti-inflammatory, anti-cancer, anti-obesity, anti-diabetogenic and anti-aging properties.
Causes of Low DHEA levels:
Menopause Andropause
Stress
Excessive alcohol consumption
Birth control pills
Hypothyroidism
Obesity
Aging
Smoking
Lack of exercise
Managing stress can help balance multiple hormone levels.
DHEA Benefits:
Increases energy
Lowers LDL cholesterol levels
Stabilizes blood sugar by lowering insulin levels
Increases immune system strength
Assists in the conversion of fat to lean muscle
Decreases cardiac risk for men
May prevent osteoporosis
DHEA peaks between 6:00 am and 1:00 pm every day.
DHEA supplements are best taken in the morning or midday.
DHEA supplements are fat-soluble and best absorbed with a meal, preferably one that includes healthy fat.
http://vitalitmed.com/hormones/dhea/
Anemia tech slides
Iron deficiency anemia is caused by a lack of iron needed to produce hemoglobin. There are multiple factors that influence iron absorption, transport, storage and utilization in hemoglobin and red blood cell production. An ideal treatment addresses these factors by providing iron along with proteins, vitamins and minerals to efficiently synthesize and mature hemoglobin and red blood cells.
Basics of heme iron and therapy
The OptiFer® series of iron food supplements
are safe, efficient and very well tolerated,
which is crucial for therapy success.
They give an optimal dose and can be used
over longer periods with no change in
efficacy and tolerance.
OptiFer® products compete favorably
with the regular synthetic supplements
Iron physiology
This document discusses iron physiology, including sources of iron from foods, daily iron requirements that vary by age and gender, and the roles of iron in the body. It describes how iron is absorbed in the small intestine, transported by transferrin in the blood, and stored or utilized in tissues. The document also addresses iron deficiency and overload, their causes, symptoms, and treatments.
Brochure librel all
Librel is a line of chelated micronutrient products from BASF for plant nutrition. It includes both single element chelates and mixed element formulations that dissolve rapidly and are compatible with other agrochemicals. Librel chelates provide stable and bioavailable micronutrients to improve plant growth and maximize yields.
AMH OVARIAN RESERVE MARKER Dr Jyoti Bhasker ,Dr. Sharda Jain Dr. Jyoti Ag...
This document summarizes markers of ovarian reserve and methods for testing ovarian reserve. It discusses how anti-Mullerian hormone (AMH) levels provide a better indicator of ovarian reserve than other markers, as AMH levels change least between cycles and are unaffected by other factors. AMH testing can help personalize infertility treatment by predicting response and tailoring stimulation protocols based on a patient's AMH level and ovarian reserve.
Ovarian reserve 2
Ovarian reserve testing is important before planning IVF cycle, ovulation induction, family planning reasons, before and after chemotherapy and radiotherapy. Ovarian reserve testing such as AMH may help also in diagnosis of granulosa cell tumors and amenorrhea.
OVARIAN RESERVE AND INFERTILITY
Women's ovarian reserve decreases with age, resulting in infertility around age 40-50. Ovarian reserve reflects the number and quality of eggs and can be assessed through markers like FSH, estradiol, AMH, antral follicle count, and ovarian volume. AMH levels provide the best predictor of ovarian reserve as they fluctuate less than FSH and correlate with antral follicle counts. Both low (<0.5 ng/mL) and high (>2.5 ng/mL) AMH levels impact fertility and IVF outcomes. AMH testing is recommended for women over 30, those with risk factors for low reserve, or who are undergoing fertility treatments.
Frontrow Business Presentation
FRONTROW is a multi-level marketing firm that distributes health, beauty and wellness products, such as: -LUXXE White (Enhanced Glutathione) -LUXXE Protect (Pure Grapeseed Extract) -LUXXE Slim (L-Carnitine & Green Tea Extract) -LUXXE Renew (8 Berry Extract) We do not conduct photo shoots. We are not looking for models. We are looking for dynamic individuals who are interested in multi-level marketing.
For orders/inquiries, you can contact yours truly, Jenina at 0910-350-3724 or visit our page, facebook.com/iLoveLuxxe
Enzymes as therapeutic agents
This document discusses enzymes that are used as therapeutic agents. It describes the properties of enzymes including their catalytic and heat-sensitive nature. Therapeutic enzymes can be used to treat various diseases safely when used with other therapies. Examples of therapeutic enzymes from animal, plant and microbial sources are provided, including streptokinase, urokinase, nattokinase and pancreatic enzymes. The mechanisms and advantages of using enzymes therapeutically are also summarized.
9 popular plant extracts in cosmetics
An introduction of 9 popular plant extracts in cosmetics. More information about Plant Extract at Alfa Chemistry.
https://www.alfa-chemistry.com/products/material-of-cosmetics-145.htm
Leveraging innovation in herbal formulations and cosmetics: Whitestone Healt...
Leveraging innovation in herbal formulations and cosmetics: Whitestone Healt...Whitestone Healthcare
This document discusses leveraging innovation in herbal formulations and cosmetics. It provides background on ancient cosmetic formulations using plant extracts from countries like Egypt, India, and Italy. It then discusses specific herbal ingredients like turmeric, sandalwood, and saffron that are used in traditional herbal formulations like ubtan paste for skin benefits. The document outlines approaches for developing herbal cosmetics following Ayurvedic principles and analyzes various plants and their phytochemicals that can be used for applications like skin care, hair care, anti-aging, and deodorizing. It also discusses the importance of quality control and standardization of herbal cosmetics.4.dr.nuell miracle fitting essence
Apharm co., Ltd. product information. Cosmetics and skin care products. Made in Korea.
http://www.tradekey.com/company/Apharm-Co-Ltd-10652657.html
Herbal cosmetics ppt
Herbal cosmetics are formulations containing herbs or herbal extracts combined with permissible cosmetic ingredients. Herbal cosmeceuticals can affect skin biological functions, while nutricosmetics contain nutraceutical and cosmetic ingredients. Herbal cosmetics are popular due to lack of adverse effects and skin friendliness, though they do not produce instant results. The document provides examples of herbal extracts used in cosmetics and their functions, classifications of herbal cosmetic formulations, herbal cosmetics for different skin types, formulations for skin care, hair care and oral care.
Class sources of drugs
This document discusses the various sources of drugs including natural sources from plants, animals, and microorganisms as well as synthetic drugs. It provides examples of commonly used drugs from different natural sources such as morphine from poppy plants, digitalis from foxglove, and penicillin from fungus. The document also notes advantages of synthetic drugs such as better quality control and the ability to modify drug structures.
Saffron
1. Saffron is a spice derived from the dried stigmas of Crocus sativus, a flower native to Greece. It contains over 150 volatile compounds that give saffron its aroma, as well as carotenoids like crocin, which have strong antioxidant effects.
2. Crocin is the main carotenoid in saffron and has stronger antioxidant activity than alpha-tocopherol. Saffron supplements are used to treat eye diseases like macular degeneration and as a natural appetite suppressant and treatment for mild to moderate depression by increasing serotonin levels.
3. Crocin is extracted from saffron through a two-step process involving ethanol extraction and crystallization at
Combating the effects of pacnes
This document summarizes how Propionibacterium acnes (P. acnes) promotes comedones and causes inflammatory responses in the skin. It discusses five ways P. acnes promotes comedones: through biofilms, the IGF pathway, aberrant integrin expression, production of free fatty acids, and oxidation of squalene. It also lists natural extracts and compounds that can target each of these mechanisms. Additionally, it outlines several inflammatory cytokines and receptors induced by P. acnes, and recommends natural extracts shown to inhibit each one. The document promotes learning more about these topics by visiting the provided website or contacting the listed email.
More Related Content
Viewers also liked
Low dose vs high-dose
Why Low-dose is more efficient than High-dose when it comes to iron .A Heme-Iron tablet with a dose of 18 mg will yield up to 4 mgs for bodily needs, whereas a non-heme tablet of 100 mg will yield 2 mg. The rest is reactive and remains in the gut.
The body will absorb no more than it needs of Heme-Iron and the rest is completely inert – no stomach problems.
Accepted statements for OptiFer®
What is a food supplement?
A food or dietary supplement is a product intended for ingestion that contains a "dietary ingredient" intended to add further nutritional value to (supplement) the diet.
What can you claim for a food or dietary supplement ?
Some dietary supplements may help to ensure that you get an adequate dietary intake of essential nutrients; others may help you reduce your risk of disease.
Iron (New Dimension)
Things people don't consider often while consuming food containing iron would be be helpful for them to understand about acquiring maximum benefits of IRON.
What do we know about heme iron II
1) Heme iron is absorbed through a specific uptake process in the duodenal mucosal cells that is not affected by other dietary components like phytates or calcium.
2) Heme iron absorption is higher than non-heme iron absorption and will not be inhibited during conditions like treatment with proton pump inhibitors that decrease stomach acid and inhibit non-heme iron absorption.
3) Heme iron supplements are better tolerated than non-heme iron supplements and have a lower therapy failure rate due to side effects, allowing for improved anemia treatment and substantial savings.
About heme iron
There are two types of iron in the diet: heme iron found naturally in meat which is efficiently absorbed by the body, and non-heme iron found in plants which must be broken down before absorption and often causes gastrointestinal side effects. Heme iron supplements containing bovine hemoglobin provide a natural form of iron that is easily absorbed without side effects, unlike synthetic non-heme iron supplements which are poorly absorbed and commonly cause issues. A Swedish company produces heme iron supplements that effectively treat iron deficiency without the problems of existing non-heme supplements.
DHEA
DHEA Transcription:
DHEA (dehydroepiandrosterone) is a steroid hormone that is produced from pregnenolone in the adrenal cortex, gonads, nervous system and brain.
About 90% of DHEA is produced in the adrenal glands.
DHEA is the precursor to:
Progesterone
Testosterone
Estrogen
Around the age of 40 most people start producing inadequate levels of DHEA.
DHEA is a base for the sex hormones, and it also helps break down fats and cholesterol.
DHEA’s properties produce weak androgenic activity and have reported anti-inflammatory, anti-cancer, anti-obesity, anti-diabetogenic and anti-aging properties.
Causes of Low DHEA levels:
Menopause Andropause
Stress
Excessive alcohol consumption
Birth control pills
Hypothyroidism
Obesity
Aging
Smoking
Lack of exercise
Managing stress can help balance multiple hormone levels.
DHEA Benefits:
Increases energy
Lowers LDL cholesterol levels
Stabilizes blood sugar by lowering insulin levels
Increases immune system strength
Assists in the conversion of fat to lean muscle
Decreases cardiac risk for men
May prevent osteoporosis
DHEA peaks between 6:00 am and 1:00 pm every day.
DHEA supplements are best taken in the morning or midday.
DHEA supplements are fat-soluble and best absorbed with a meal, preferably one that includes healthy fat.
http://vitalitmed.com/hormones/dhea/
Anemia tech slides
Iron deficiency anemia is caused by a lack of iron needed to produce hemoglobin. There are multiple factors that influence iron absorption, transport, storage and utilization in hemoglobin and red blood cell production. An ideal treatment addresses these factors by providing iron along with proteins, vitamins and minerals to efficiently synthesize and mature hemoglobin and red blood cells.
Basics of heme iron and therapy
The OptiFer® series of iron food supplements
are safe, efficient and very well tolerated,
which is crucial for therapy success.
They give an optimal dose and can be used
over longer periods with no change in
efficacy and tolerance.
OptiFer® products compete favorably
with the regular synthetic supplements
Iron physiology
This document discusses iron physiology, including sources of iron from foods, daily iron requirements that vary by age and gender, and the roles of iron in the body. It describes how iron is absorbed in the small intestine, transported by transferrin in the blood, and stored or utilized in tissues. The document also addresses iron deficiency and overload, their causes, symptoms, and treatments.
Brochure librel all
Librel is a line of chelated micronutrient products from BASF for plant nutrition. It includes both single element chelates and mixed element formulations that dissolve rapidly and are compatible with other agrochemicals. Librel chelates provide stable and bioavailable micronutrients to improve plant growth and maximize yields.
AMH OVARIAN RESERVE MARKER Dr Jyoti Bhasker ,Dr. Sharda Jain Dr. Jyoti Ag...
This document summarizes markers of ovarian reserve and methods for testing ovarian reserve. It discusses how anti-Mullerian hormone (AMH) levels provide a better indicator of ovarian reserve than other markers, as AMH levels change least between cycles and are unaffected by other factors. AMH testing can help personalize infertility treatment by predicting response and tailoring stimulation protocols based on a patient's AMH level and ovarian reserve.
Ovarian reserve 2
Ovarian reserve testing is important before planning IVF cycle, ovulation induction, family planning reasons, before and after chemotherapy and radiotherapy. Ovarian reserve testing such as AMH may help also in diagnosis of granulosa cell tumors and amenorrhea.
OVARIAN RESERVE AND INFERTILITY
Women's ovarian reserve decreases with age, resulting in infertility around age 40-50. Ovarian reserve reflects the number and quality of eggs and can be assessed through markers like FSH, estradiol, AMH, antral follicle count, and ovarian volume. AMH levels provide the best predictor of ovarian reserve as they fluctuate less than FSH and correlate with antral follicle counts. Both low (<0.5 ng/mL) and high (>2.5 ng/mL) AMH levels impact fertility and IVF outcomes. AMH testing is recommended for women over 30, those with risk factors for low reserve, or who are undergoing fertility treatments.
Frontrow Business Presentation
FRONTROW is a multi-level marketing firm that distributes health, beauty and wellness products, such as: -LUXXE White (Enhanced Glutathione) -LUXXE Protect (Pure Grapeseed Extract) -LUXXE Slim (L-Carnitine & Green Tea Extract) -LUXXE Renew (8 Berry Extract) We do not conduct photo shoots. We are not looking for models. We are looking for dynamic individuals who are interested in multi-level marketing.
For orders/inquiries, you can contact yours truly, Jenina at 0910-350-3724 or visit our page, facebook.com/iLoveLuxxe
Viewers also liked (14)
AMH OVARIAN RESERVE MARKER Dr Jyoti Bhasker ,Dr. Sharda Jain Dr. Jyoti Ag...
AMH OVARIAN RESERVE MARKER Dr Jyoti Bhasker ,Dr. Sharda Jain Dr. Jyoti Ag...
Similar to 5a reductase inhibitors a novel approach to treating acne
Enzymes as therapeutic agents
This document discusses enzymes that are used as therapeutic agents. It describes the properties of enzymes including their catalytic and heat-sensitive nature. Therapeutic enzymes can be used to treat various diseases safely when used with other therapies. Examples of therapeutic enzymes from animal, plant and microbial sources are provided, including streptokinase, urokinase, nattokinase and pancreatic enzymes. The mechanisms and advantages of using enzymes therapeutically are also summarized.
9 popular plant extracts in cosmetics
An introduction of 9 popular plant extracts in cosmetics. More information about Plant Extract at Alfa Chemistry.
https://www.alfa-chemistry.com/products/material-of-cosmetics-145.htm
Leveraging innovation in herbal formulations and cosmetics: Whitestone Healt...
Leveraging innovation in herbal formulations and cosmetics: Whitestone Healt...Whitestone Healthcare
This document discusses leveraging innovation in herbal formulations and cosmetics. It provides background on ancient cosmetic formulations using plant extracts from countries like Egypt, India, and Italy. It then discusses specific herbal ingredients like turmeric, sandalwood, and saffron that are used in traditional herbal formulations like ubtan paste for skin benefits. The document outlines approaches for developing herbal cosmetics following Ayurvedic principles and analyzes various plants and their phytochemicals that can be used for applications like skin care, hair care, anti-aging, and deodorizing. It also discusses the importance of quality control and standardization of herbal cosmetics.4.dr.nuell miracle fitting essence
Apharm co., Ltd. product information. Cosmetics and skin care products. Made in Korea.
http://www.tradekey.com/company/Apharm-Co-Ltd-10652657.html
Herbal cosmetics ppt
Herbal cosmetics are formulations containing herbs or herbal extracts combined with permissible cosmetic ingredients. Herbal cosmeceuticals can affect skin biological functions, while nutricosmetics contain nutraceutical and cosmetic ingredients. Herbal cosmetics are popular due to lack of adverse effects and skin friendliness, though they do not produce instant results. The document provides examples of herbal extracts used in cosmetics and their functions, classifications of herbal cosmetic formulations, herbal cosmetics for different skin types, formulations for skin care, hair care and oral care.
Class sources of drugs
This document discusses the various sources of drugs including natural sources from plants, animals, and microorganisms as well as synthetic drugs. It provides examples of commonly used drugs from different natural sources such as morphine from poppy plants, digitalis from foxglove, and penicillin from fungus. The document also notes advantages of synthetic drugs such as better quality control and the ability to modify drug structures.
Saffron
1. Saffron is a spice derived from the dried stigmas of Crocus sativus, a flower native to Greece. It contains over 150 volatile compounds that give saffron its aroma, as well as carotenoids like crocin, which have strong antioxidant effects.
2. Crocin is the main carotenoid in saffron and has stronger antioxidant activity than alpha-tocopherol. Saffron supplements are used to treat eye diseases like macular degeneration and as a natural appetite suppressant and treatment for mild to moderate depression by increasing serotonin levels.
3. Crocin is extracted from saffron through a two-step process involving ethanol extraction and crystallization at
Combating the effects of pacnes
This document summarizes how Propionibacterium acnes (P. acnes) promotes comedones and causes inflammatory responses in the skin. It discusses five ways P. acnes promotes comedones: through biofilms, the IGF pathway, aberrant integrin expression, production of free fatty acids, and oxidation of squalene. It also lists natural extracts and compounds that can target each of these mechanisms. Additionally, it outlines several inflammatory cytokines and receptors induced by P. acnes, and recommends natural extracts shown to inhibit each one. The document promotes learning more about these topics by visiting the provided website or contacting the listed email.
Dxn
The document introduces several natural health products from DXN including Ganoderma-based supplements, beverages, toothpaste, shampoo, soap, and massage oil. It discusses the benefits of these products for improving immunity, health, energy levels, and skin and hair quality. The founder's background and achievements in herbal medicine are also summarized.
Tim&Lil
The document discusses the Time Defiance Intensive Repair Serum, which contains a Deep Night Action Complex to repair signs of aging. The complex includes ultrasomes containing an enzyme that enhances DNA repair, a vitamin C derivative, licorice root extract, and alpinia leaf extract. It is designed to stimulate the skin's natural repair mechanisms while you sleep. Clinical tests found it improved skin clarity, smoothness, and reduced fine lines and dryness after 14 days of nightly use. The serum is recommended for 3-4 uses per year to continuously repair skin from environmental stresses.
Genetic Skin Health
Ginny Bank is the Director of Product Education and Technical Support for GeneWize Life Sciences. She has significant experience in the dietary supplement industry as a natural products chemist. Ms. Bank holds four U.S. patents pertaining to antioxidants and their applications.
The LifeMap Me Skin Repair Serum Formula is a scientifically-proven anti-wrinkle firming formulation customized for each user based on their genetically-determined skin care needs. The formula contains a base serum for all skin types plus additional SNPActives targeted to issues identified in the user's genetic skin profile. Each SNPActive is designed to address a specific genetic marker and has been tested to demonstrate its effect.
Quantified Self & Biohacking
Introductory presentation to the topic of quantified self & biohacking at the QS & Biohacking Meetup Helsinki. 25th of March 2013.
tannins.pptx
Tannins are phenolic compounds found in plants that can precipitate proteins. They are classified as true tannins, pseudotannins, hydrolysable tannins, and condensed tannins. Hydrolysable tannins include gallitannins and ellagitannins that break down into gallic acid or ellagic acid. Condensed tannins are polymeric flavan-3-ols like catechin. Tannins are identified through tests like reaction with iron salts or bromine water. They have industrial uses in tanning leather and making ink, and medicinal uses as astringents and antioxidants in conditions like diarrhea, burns, and inflamed skin. Major commercial sources
Phytochemical Screening, Isolation & Characterization of the compounds from e...
This document describes research on the isolation and characterization of compounds from the seeds of Annona squamosa. The objectives were to extract compounds from the seeds, perform phytochemical screening of the extracts, and isolate and evaluate the chemical structure of any cardiac glycosides present. The methodology included extraction of the seeds using solvents, phytochemical analysis, thin layer chromatography, column chromatography, and various spectroscopic techniques. Analysis indicated the presence of cardiac glycosides and characterization suggested the isolated compound was a bufadienolide with a probable structure similar to other known cardiac glycosides.
TNJ Science Presentation
Did You Know...the amazing health benefits of Tahitian Noni Juice are proven in human clinical trials? Check out this presentation if you want to optimize your health.
Natural Products and Phytomedicines for Acne
Acne is a common skin condition, caused by changes in the pilosebaceous units, skin structures consisting of hair follicles, and its associated sebaceous glands via androgen stimulation. Acne is a disease whose initial pathology is the microscopic microcomedo. The microcomedo may involve into visible open comedones (Blackheads) or closed comedones (Whiteheads). Subsequently, inflammatory papules, pustules, and nodules may develop.
The severity of acne varies greatly among individuals and a genetic background plays an important role. Pathogenic factors include androgen-induced seborrhea, follicular hyperkeratosis, microbial population, and immunological and inflammatory processes. These factors influence each other, leading to acne phenotype. It is estimated that as many as 90% of all teenagers are affected by acne, with virtually 100% of teenagers experiencing some degree of comedone formation. Acne may be inflammatory or non-inflammatory acne lesions including open and closed comedones. Inflammatory lesions include papules, pustules, and nodules. The initial event in the development of an acne lesion is abnormal desquamation of the keratinocytes that line the sebaceous follicle, which creates a microcomedo.
An increase in circulating androgens at the onset of puberty stimulates the production of sebum into the pilosebaceous unit that is favorable for colonization of the commensal bacteria, Propionibacterium acnes (P. acnes). With proliferation, P. acnes secrete various inflammatory molecules and chemotactic factors that initiate and perpetuate the local inflammatory response and possibly induce keratinocyte hyperproliferation as well. Sebum plays a central role in the pathogenesis of acne.
Natural Products and Phytomedicines for Acne
Acne is a common skin condition, caused by changes in the pilosebaceous units, skin structures consisting of hair follicles, and its associated sebaceous glands via androgen stimulation. Acne is a disease whose initial pathology is the microscopic microcomedo. The microcomedo may involve into visible open comedones (Blackheads) or closed comedones (Whiteheads). Subsequently, inflammatory papules, pustules, and nodules may develop.
The severity of acne varies greatly among individuals and a genetic background plays an important role. Pathogenic factors include androgen-induced seborrhea, follicular hyperkeratosis, microbial population, and immunological and inflammatory processes. These factors influence each other, leading to acne phenotype. It is estimated that as many as 90% of all teenagers are affected by acne, with virtually 100% of teenagers experiencing some degree of comedone formation. Acne may be inflammatory or non-inflammatory acne lesions including open and closed comedones. Inflammatory lesions include papules, pustules, and nodules. The initial event in the development of an acne lesion is abnormal desquamation of the keratinocytes that line the sebaceous follicle, which creates a microcomedo.
An increase in circulating androgens at the onset of puberty stimulates the production of sebum into the pilosebaceous unit that is favorable for colonization of the commensal bacteria, Propionibacterium acnes (P. acnes). With proliferation, P. acnes secrete various inflammatory molecules and chemotactic factors that initiate and perpetuate the local inflammatory response and possibly induce keratinocyte hyperproliferation as well. Sebum plays a central role in the pathogenesis of acne.
Dxn presentation
Read this presentation thoroughly, it can help you to make a big change in ur life.
my mail ID is chlox_66@yahoo.co.in
Organi Care
Our OrganiCare cosmetics products contain valuable active ingredients from herbs produced on organic farms. During our traditional production method that follows manual harvesting and involves great attention and control, we do not use any kind of chemical processing aids to ensure preservation of the entire effect of the valuable components. This results in products of extremely high quality, pureness and effectiveness.
The OrganiCare product family contains a shower gel, a body lotion, a shampoo, a hair conditioner, two different types of toothpaste and a first aid balm. Thanks to the gentle care provided by our natural, allergen-free ingredients, the whole family can use our products so it is the ideal choice for children and people with sensitive skin alike.
Cosmetics
This document provides an overview of natural products used in cosmetics. It discusses various plant-derived oils, extracts and compounds and their uses and benefits in skin care, hair care and as essential oils. Some mentioned are coconut oil, sunflower oil, jojoba oil, olive oil, aloe vera, henna and essential oils such as rose oil and eucalyptus oil. The document also covers extraction methods, chemical constituents and pharmacological properties of these natural ingredients used widely in cosmetics.
Similar to 5a reductase inhibitors a novel approach to treating acne (20)
Leveraging innovation in herbal formulations and cosmetics: Whitestone Healt...
Leveraging innovation in herbal formulations and cosmetics: Whitestone Healt...
Phytochemical Screening, Isolation & Characterization of the compounds from e...
Phytochemical Screening, Isolation & Characterization of the compounds from e...
More from Jacine Greenwood
The aging skin managing glycation
The document is a presentation on glycation and aging skin. It discusses what glycation is, how foods and certain ingredients can contribute to or prevent glycation. Several plants and ingredients are listed that have anti-glycation properties. The effects of advanced glycation end products on skin morphology and physiology during aging are covered. Specific anti-glycation actives and products are mentioned. The presentation concludes with an announcement of a new subscription for educated therapists.
Atp and mitochondria
ATP (adenosine triphosphate) production declines with age due to mitochondrial dysfunction. Mitochondria are the primary producers of cellular energy in the form of ATP through oxidative phosphorylation. As we age, mitochondrial DNA mutations accumulate, impairing ATP production. This summary discusses strategies to increase ATP levels topically and through supplementation to enhance mitochondrial function and combat signs of aging. These include vitamins B1-B6, biotin, B12, folic acid, magnesium, alpha lipoic acid, carnitine, NADH, coenzyme Q10, creatine, and LED or microcurrent therapy. Maintaining optimal mitochondrial and ATP levels may help slow the visible signs of skin aging.
Parabens notes
Parabens are commonly used preservatives that provide antibacterial and antifungal properties. While some studies have claimed parabens may disrupt hormones or increase cancer risk, many experts argue these studies are flawed and the evidence does not support these claims. Parabens are found naturally in many plants and pose substantially less risk than naturally occurring endocrine disruptors when used in normal amounts as preservatives in cosmetics. The consensus among health and regulatory organizations is that parabens are safe to use as preservatives when used properly.
Combating the effects of pacnes
This document discusses various agents that can be used to treat acne by disrupting biofilms formed by Propionibacterium acnes bacteria. Retinoids normalize skin cell shedding and decrease inflammation by altering the biofilm. Benzoyl peroxide is bactericidal against both aerobic and anaerobic organisms by producing free radicals. Acids prevent biofilm attachment to skin walls. Resveratrol eradicates biofilms and inhibits excessive skin cell growth. Turmeric and compounds in various plants like magnolia, nigella sativa, and manuka oil exhibit anti-inflammatory and antimicrobial properties against P. acnes through mechanisms such as suppressing free radical production and inhibiting factors that promote inflammation.
Webinar p acnes
p. Acnes plays more of a pathogenic role in the development of acne then previously thought. In this webinar you will learn more about how specifically p.Acnes helps to form the microcomedone. Why fruit acids work with acne....and it's not the reason you think it is.
Why some companies treat all acne the same and why this is successful.
P acnes and its role in acne formation
Propionibacterium acnes (p. Acnes) bacteria are classified into different types based on gene sequencing and biological characteristics and play a role in acne formation. P. acnes promotes comedones through biofilms, the IGF pathway, aberrant integrin expression, production of free fatty acids, and oxidation of squalene. P. acnes also interacts with toll-like receptors and forms biofilms that contribute to acne.
5a reductase webinar
Sebum production is controlled by androgens like testosterone and dihydrotestosterone (DHT). Testosterone is converted to the more potent DHT by the enzyme 5α-reductase type I in sebaceous glands. Higher levels of 5α-reductase type I and DHT in acne-prone areas leads to increased sebum production and acne severity. Certain foods and supplements can influence 5α-reductase activity and androgen levels, thereby affecting acne. Ingredients like reishi mushroom, zinc, and eucalyptus have been shown to inhibit 5α-reductase and could potentially reduce acne by decreasing sebum production.
More from Jacine Greenwood (7)
Recently uploaded
How to Add Chatter in the odoo 17 ERP Module
In Odoo, the chatter is like a chat tool that helps you work together on records. You can leave notes and track things, making it easier to talk with your team and partners. Inside chatter, all communication history, activity, and changes will be displayed.
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
Let’s explore the intersection of technology and equity in the final session of our DEI series. Discover how AI tools, like ChatGPT, can be used to support and enhance your nonprofit's DEI initiatives. Participants will gain insights into practical AI applications and get tips for leveraging technology to advance their DEI goals.
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
Denis is a dynamic and results-driven Chief Information Officer (CIO) with a distinguished career spanning information systems analysis and technical project management. With a proven track record of spearheading the design and delivery of cutting-edge Information Management solutions, he has consistently elevated business operations, streamlined reporting functions, and maximized process efficiency.
Certified as an ISO/IEC 27001: Information Security Management Systems (ISMS) Lead Implementer, Data Protection Officer, and Cyber Risks Analyst, Denis brings a heightened focus on data security, privacy, and cyber resilience to every endeavor.
His expertise extends across a diverse spectrum of reporting, database, and web development applications, underpinned by an exceptional grasp of data storage and virtualization technologies. His proficiency in application testing, database administration, and data cleansing ensures seamless execution of complex projects.
What sets Denis apart is his comprehensive understanding of Business and Systems Analysis technologies, honed through involvement in all phases of the Software Development Lifecycle (SDLC). From meticulous requirements gathering to precise analysis, innovative design, rigorous development, thorough testing, and successful implementation, he has consistently delivered exceptional results.
Throughout his career, he has taken on multifaceted roles, from leading technical project management teams to owning solutions that drive operational excellence. His conscientious and proactive approach is unwavering, whether he is working independently or collaboratively within a team. His ability to connect with colleagues on a personal level underscores his commitment to fostering a harmonious and productive workplace environment.
Date: May 29, 2024
Tags: Information Security, ISO/IEC 27001, ISO/IEC 42001, Artificial Intelligence, GDPR
-------------------------------------------------------------------------------
Find out more about ISO training and certification services
Training: ISO/IEC 27001 Information Security Management System - EN | PECB
ISO/IEC 42001 Artificial Intelligence Management System - EN | PECB
General Data Protection Regulation (GDPR) - Training Courses - EN | PECB
Webinars: https://pecb.com/webinars
Article: https://pecb.com/article
-------------------------------------------------------------------------------
For more information about PECB:
Website: https://pecb.com/
LinkedIn: https://www.linkedin.com/company/pecb/
Facebook: https://www.facebook.com/PECBInternational/
Slideshare: http://www.slideshare.net/PECBCERTIFICATION
The Diamonds of 2023-2024 in the IGRA collection
A review of the growth of the Israel Genealogy Research Association Database Collection for the last 12 months. Our collection is now passed the 3 million mark and still growing. See which archives have contributed the most. See the different types of records we have, and which years have had records added. You can also see what we have for the future.
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptxMohd Adib Abd Muin, Senior Lecturer at Universiti Utara Malaysia
This slide is special for master students (MIBS & MIFB) in UUM. Also useful for readers who are interested in the topic of contemporary Islamic banking.
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Aberdeen
Pengantar Penggunaan Flutter - Dart programming language1.pptx
Pengantar Penggunaan Flutter - Dart programming language1.pptx
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
it describes the bony anatomy including the femoral head , acetabulum, labrum . also discusses the capsule , ligaments . muscle that act on the hip joint and the range of motion are outlined. factors affecting hip joint stability and weight transmission through the joint are summarized.
RPMS TEMPLATE FOR SCHOOL YEAR 2023-2024 FOR TEACHER 1 TO TEACHER 3
RPMS Template 2023-2024 by: Irene S. Rueco
Community pharmacy- Social and preventive pharmacy UNIT 5
Covered community pharmacy topic of the subject Social and preventive pharmacy for Diploma and Bachelor of pharmacy
The History of Stoke Newington Street Names
Presented at the Stoke Newington Literary Festival on 9th June 2024
www.StokeNewingtonHistory.com
How to Setup Warehouse & Location in Odoo 17 Inventory
In this slide, we'll explore how to set up warehouses and locations in Odoo 17 Inventory. This will help us manage our stock effectively, track inventory levels, and streamline warehouse operations.
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UP
This Dissertation explores the particular circumstances of Mirzapur, a region located in the
core of India. Mirzapur, with its varied terrains and abundant biodiversity, offers an optimal
environment for investigating the changes in vegetation cover dynamics. Our study utilizes
advanced technologies such as GIS (Geographic Information Systems) and Remote sensing to
analyze the transformations that have taken place over the course of a decade.
The complex relationship between human activities and the environment has been the focus
of extensive research and worry. As the global community grapples with swift urbanization,
population expansion, and economic progress, the effects on natural ecosystems are becoming
more evident. A crucial element of this impact is the alteration of vegetation cover, which plays a
significant role in maintaining the ecological equilibrium of our planet.Land serves as the foundation for all human activities and provides the necessary materials for
these activities. As the most crucial natural resource, its utilization by humans results in different
'Land uses,' which are determined by both human activities and the physical characteristics of the
land.
The utilization of land is impacted by human needs and environmental factors. In countries
like India, rapid population growth and the emphasis on extensive resource exploitation can lead
to significant land degradation, adversely affecting the region's land cover.
Therefore, human intervention has significantly influenced land use patterns over many
centuries, evolving its structure over time and space. In the present era, these changes have
accelerated due to factors such as agriculture and urbanization. Information regarding land use and
cover is essential for various planning and management tasks related to the Earth's surface,
providing crucial environmental data for scientific, resource management, policy purposes, and
diverse human activities.
Accurate understanding of land use and cover is imperative for the development planning
of any area. Consequently, a wide range of professionals, including earth system scientists, land
and water managers, and urban planners, are interested in obtaining data on land use and cover
changes, conversion trends, and other related patterns. The spatial dimensions of land use and
cover support policymakers and scientists in making well-informed decisions, as alterations in
these patterns indicate shifts in economic and social conditions. Monitoring such changes with the
help of Advanced technologies like Remote Sensing and Geographic Information Systems is
crucial for coordinated efforts across different administrative levels. Advanced technologies like
Remote Sensing and Geographic Information Systems
9
Changes in vegetation cover refer to variations in the distribution, composition, and overall
structure of plant communities across different temporal and spatial scales. These changes can
occur natural.
Natural birth techniques - Mrs.Akanksha Trivedi Rama University
Natural birth techniques - Mrs.Akanksha Trivedi Rama UniversityAkanksha trivedi rama nursing college kanpur.
Natural birth techniques are various type such as/ water birth , alexender method, hypnosis, bradley method, lamaze method etcRecently uploaded (20)
Liberal Approach to the Study of Indian Politics.pdf
Liberal Approach to the Study of Indian Politics.pdf
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
Digital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental Design
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
Pengantar Penggunaan Flutter - Dart programming language1.pptx
Pengantar Penggunaan Flutter - Dart programming language1.pptx
RPMS TEMPLATE FOR SCHOOL YEAR 2023-2024 FOR TEACHER 1 TO TEACHER 3
RPMS TEMPLATE FOR SCHOOL YEAR 2023-2024 FOR TEACHER 1 TO TEACHER 3
Community pharmacy- Social and preventive pharmacy UNIT 5
Community pharmacy- Social and preventive pharmacy UNIT 5
How to Setup Warehouse & Location in Odoo 17 Inventory
How to Setup Warehouse & Location in Odoo 17 Inventory
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UP
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UP
Natural birth techniques - Mrs.Akanksha Trivedi Rama University
Natural birth techniques - Mrs.Akanksha Trivedi Rama University
5a reductase inhibitors a novel approach to treating acne
- 1. 5a Reductase Inhibitors A Refreshing Approach to Treating Acne
- 4. Which comes first …..
- 8. 5a Reductase Inhibitors There are 2 types of isozymes of 5a reductase. Type 1 and type 2.
- 9. Endogenous sources of DHT 5α-androstanedione and 5α-pregnanedione
- 10. Insulin and Insulin like growth factor
- 11. Sex Hormone Binding Globulin
- 13. Reishi
- 15. Eucalyptus
- 16. Licorice
- 17. Saw Palmetto
- 18. Green Tea
- 20. Curcumin
- 21. Rosemary Extract
- 22. Nettle Extract
- 23. Resveratrol
- 24. Does it work?
- 25. Does it work?
- 26. How have we used this research? Plant Harmonising Serum Contains: Green Tea Saw Palmetto Extract Bellamcanda Chinensis Extract Nettle Extract Rosemary Extract Licorice Extract Curcumin Niacinamide L-Carnitine
- 27. How have we used this research? Magnolia Honey Cream Contains: Resveratrol
- 28. If you would like to know more www.roccoco.com.au Or jacine@roccoco.com.au
- 29. Next Webinar….. Monday 17th Feb AEST at 9am. Topic: The Aetiology of Acne….New discoveries from current research
Editor's Notes
- 3 different receptors have been identified for stimulating sebum.
- 3 different receptors have been identified for stimulating sebum.
- 3 different receptors have been identified for stimulating sebum.
- 3 different receptors have been identified for stimulating sebum.