19/07/2015	
  
1	
  
The Aging Skin
Managing Glycation
Jacine Greenwood
Founder	
  of	
  Roccoco	
  
Founder	
  of	
  Educated	
  Therapists	
  
Interna<onal	
  Speaker	
  
Mother	
  of	
  3	
  Beau<ful	
  Children	
  
Passion	
  -­‐	
  Skincare	
  
	
  
	
  
	
  
	
  
	
  
19/07/2015	
  
2	
  
Outline
•  What	
  is	
  Glyca<on	
  
•  How	
  does	
  food	
  contribute	
  to	
  glyca<on	
  
•  What	
  foods	
  are	
  an<-­‐glyca<on	
  
•  Can	
  glyca<on	
  be	
  reversed?	
  
•  What	
  ac<ves	
  prevent	
  glyca<on?	
  
•  What	
  ac<ves	
  reverse	
  glyca<on?	
  
	
  
	
  
	
  
	
   Glyca<on	
  occurs	
  when	
  a	
  sugar	
  
molecule,	
  such	
  as	
  glucose	
  or	
  
fructose,	
  covalently	
  bonds	
  with	
  a	
  
protein	
  or	
  lipid	
  	
  
19/07/2015	
  
3	
  
Foods	
  high	
  in	
  AGEs	
  
	
  
	
  
	
  
	
  
19/07/2015	
  
4	
  
Foods	
  low	
  in	
  AGEs	
  
Foods that inhibit AGE
•  Cinnamon 	
   	
  Cloves 	
   	
  Oregano	
  
•  Allspice 	
   	
   	
  Sage	
   	
   	
  Thyme	
  
•  Rosemary 	
   	
  Marjoram	
  
Dearlove,	
  R;	
  Greenspan,	
  P;	
  Hartle,D;	
  Swanson	
  and	
  Hargrove,	
  J.	
  “Inhibi<on	
  of	
  Protein	
  
Glyca<on	
  by	
  Extracts	
  of	
  Culinary	
  Herbs	
  and	
  Spices”	
  J	
  Med	
  Food	
  11	
  (2)	
  2008,	
  275–281	
  
Foods that inhibit AGE
19/07/2015	
  
5	
  
Foods that inhibit AGEs
URIBARRI,	
  J;	
  WOODRUFF,	
  S;	
  GOODMAN,	
  S;	
  CAI,	
  W;	
  CHEN,	
  X;	
  PYZIK,	
  R;	
  YONG,	
  A;	
  STRIKER,	
  
G;	
  VLASSARA,	
  H.	
  (2010)	
  “Advanced	
  Glyca<on	
  End	
  Products	
  in	
  Foods	
  and	
  a	
  Prac<cal	
  Guide	
  
to	
  Their	
  Reduc<on	
  in	
  the	
  Diet”	
  	
  	
  J	
  Am	
  Diet	
  Assoc.	
  2010;110:911-­‐916.	
  
	
  
	
  	
  
MEDICATIONS THAT
INHIBIT THE GLYCATION
PROCESS
19/07/2015	
  
6	
  
Effects	
  of	
  AGEs/RAGE	
  on	
  skin	
  morphology	
  and	
  physiology	
  
during	
  aging*	
  	
  
	
  
	
  
	
  	
  
ACTIVES THAT INHIBIT
THE GLYCATION
PROCESS
	
  
	
  
Hydnora johannis roots extract
19/07/2015	
  
7	
  
Collrepair	
  –	
  Sage	
  and	
  Niacin	
  
Rosamox	
  
	
  
	
  
	
  
ALASTIN
19/07/2015	
  
8	
  
	
  
	
  
	
  
	
  
AMELIOX	
  
Prodizia	
  –	
  Persian	
  Silk	
  Tree	
  
19/07/2015	
  
9	
  
Prodizia	
  
Persian	
  Silk	
  Tree	
  Extract	
  
Sour	
  Cherry	
  Extract	
  
Plants	
  known	
  to	
  have	
  an<-­‐glyca<on	
  
ac<vity	
  
•  Centella	
  Asia<ca	
  
•  Davilla	
  Rugosa	
  Leaf	
  Extract	
  
•  Cherry	
  Blossom	
  Extract	
  
•  Withania	
  Somniferia	
  
•  Kiwifruit	
  
•  Onion	
  
•  Aloe	
  
19/07/2015	
  
10	
  
Plants	
  known	
  to	
  have	
  an<-­‐glyca<on	
  
ac<vity	
  
•  Roman	
  Chamomile	
  
•  Asparagus	
  
•  Neem	
  
•  Calendula	
  
•  Green	
  Tea	
  
•  Centella	
  
•  Cinnamon	
  
Plants	
  known	
  to	
  have	
  an<-­‐glyca<on	
  
ac<vity	
  
•  Coffee	
  
•  Hawthorn	
  
•  Cumin	
  	
  
•  Cypress	
  
•  Turmeric	
  
•  Emblica	
  
•  Mate	
  
Plants	
  known	
  to	
  have	
  an<-­‐glyca<on	
  
ac<vity	
  
•  Peppermint	
  
•  Lemon	
  Balm	
  
•  Nutmeg	
  
•  Basil	
  
•  Marjoram	
  
•  Passionfruit	
  
•  Ginseng	
  
19/07/2015	
  
11	
  
Plants	
  known	
  to	
  have	
  an<-­‐glyca<on	
  
ac<vity	
  
•  Guava	
  
•  Pomegranate	
  
•  Rhodiola	
  
•  Rosemary	
  
•  Tamarind	
  
•  Terminalia	
  Chebulia	
  
•  Violet	
  
	
  
	
  
	
  
Results
	
  
	
  
	
  
	
  
19/07/2015	
  
12	
  
	
  
	
  
	
  
	
  
19/07/2015	
  
13	
  
We	
  are	
  launching	
  a	
  new	
  subscrip<on	
  for	
  
Educated	
  Therapists.	
  
	
  
For	
  more	
  info:	
  
www.educatedtherapists.com	
  

The aging skin managing glycation

  • 1.
    19/07/2015   1   TheAging Skin Managing Glycation Jacine Greenwood Founder  of  Roccoco   Founder  of  Educated  Therapists   Interna<onal  Speaker   Mother  of  3  Beau<ful  Children   Passion  -­‐  Skincare            
  • 2.
    19/07/2015   2   Outline • What  is  Glyca<on   •  How  does  food  contribute  to  glyca<on   •  What  foods  are  an<-­‐glyca<on   •  Can  glyca<on  be  reversed?   •  What  ac<ves  prevent  glyca<on?   •  What  ac<ves  reverse  glyca<on?           Glyca<on  occurs  when  a  sugar   molecule,  such  as  glucose  or   fructose,  covalently  bonds  with  a   protein  or  lipid    
  • 3.
    19/07/2015   3   Foods  high  in  AGEs          
  • 4.
    19/07/2015   4   Foods  low  in  AGEs   Foods that inhibit AGE •  Cinnamon    Cloves    Oregano   •  Allspice      Sage      Thyme   •  Rosemary    Marjoram   Dearlove,  R;  Greenspan,  P;  Hartle,D;  Swanson  and  Hargrove,  J.  “Inhibi<on  of  Protein   Glyca<on  by  Extracts  of  Culinary  Herbs  and  Spices”  J  Med  Food  11  (2)  2008,  275–281   Foods that inhibit AGE
  • 5.
    19/07/2015   5   Foodsthat inhibit AGEs URIBARRI,  J;  WOODRUFF,  S;  GOODMAN,  S;  CAI,  W;  CHEN,  X;  PYZIK,  R;  YONG,  A;  STRIKER,   G;  VLASSARA,  H.  (2010)  “Advanced  Glyca<on  End  Products  in  Foods  and  a  Prac<cal  Guide   to  Their  Reduc<on  in  the  Diet”      J  Am  Diet  Assoc.  2010;110:911-­‐916.         MEDICATIONS THAT INHIBIT THE GLYCATION PROCESS
  • 6.
    19/07/2015   6   Effects  of  AGEs/RAGE  on  skin  morphology  and  physiology   during  aging*             ACTIVES THAT INHIBIT THE GLYCATION PROCESS     Hydnora johannis roots extract
  • 7.
    19/07/2015   7   Collrepair  –  Sage  and  Niacin   Rosamox         ALASTIN
  • 8.
    19/07/2015   8           AMELIOX   Prodizia  –  Persian  Silk  Tree  
  • 9.
    19/07/2015   9   Prodizia   Persian  Silk  Tree  Extract   Sour  Cherry  Extract   Plants  known  to  have  an<-­‐glyca<on   ac<vity   •  Centella  Asia<ca   •  Davilla  Rugosa  Leaf  Extract   •  Cherry  Blossom  Extract   •  Withania  Somniferia   •  Kiwifruit   •  Onion   •  Aloe  
  • 10.
    19/07/2015   10   Plants  known  to  have  an<-­‐glyca<on   ac<vity   •  Roman  Chamomile   •  Asparagus   •  Neem   •  Calendula   •  Green  Tea   •  Centella   •  Cinnamon   Plants  known  to  have  an<-­‐glyca<on   ac<vity   •  Coffee   •  Hawthorn   •  Cumin     •  Cypress   •  Turmeric   •  Emblica   •  Mate   Plants  known  to  have  an<-­‐glyca<on   ac<vity   •  Peppermint   •  Lemon  Balm   •  Nutmeg   •  Basil   •  Marjoram   •  Passionfruit   •  Ginseng  
  • 11.
    19/07/2015   11   Plants  known  to  have  an<-­‐glyca<on   ac<vity   •  Guava   •  Pomegranate   •  Rhodiola   •  Rosemary   •  Tamarind   •  Terminalia  Chebulia   •  Violet         Results        
  • 12.
  • 13.
    19/07/2015   13   We  are  launching  a  new  subscrip<on  for   Educated  Therapists.     For  more  info:   www.educatedtherapists.com