Iron is essential for life. Daily intake should be at least 18 mg of iron to compensate for losses. Heme iron is taken up at 20 – 40 % compared to non-heme 2 – 4 %, such as for example Ferrous Sulphate. This means that one tablet of OptiFer® will give up to 7,2 mgs of absorbed iron. This is more than 150 mgs of non-heme iron will give. Unpleasant side effects are dose-related and present in more than 30 % of therapies with non-heme iron. In studies the tolerance of heme iron is virtually perfect.