This document discusses adrenergic antagonists, which are drugs that inhibit the function of adrenergic receptors. There are five adrenergic receptors divided into two groups - beta receptors (β1, β2, β3) and alpha receptors (α1, α2). Adrenergic antagonists reduce or block signals from adrenergic agonists. The effects of alpha and beta antagonists differ. Alpha antagonists cause vasodilation by blocking alpha receptors that cause vasoconstriction, while beta antagonists diffuse through the GI tract and bind to proteins before metabolizing in the liver or being eliminated unchanged. Examples of alpha and beta antagonists are provided.