Pharmachemistry is the science at the intersection of chemistry and pharmacology involved with designing, synthesizing, and developing pharmaceutical drugs. It deals with discovering new therapeutic chemicals and developing them into medicines. Pharmachemists study how to make new compounds, determine their biological effects, optimize their structure for efficacy and safety, and examine how drugs are absorbed, distributed, metabolized, and excreted. Drug activity can be structurally specific, depending on interactions with cellular receptors, or non-specific, relating to physical properties like solubility.