Presentation by Daniel Simões, HIV in Europe, Portugal , at AIDS 2018 conference during the joint ECDC and EACS satellite "Getting to 90: Addressing inequalities in the HIV continuum of care in Europe and Central Asia"
How to Give Better Lectures: Some Tips for Doctors
Addressing the first 90: How can HIV testing more efficiently reach those in need to promote early diagnosis?
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Addressing the first 90: How can HIV
testing more efficiently reach those in
need to promote early diagnosis?
Daniel Simões
HIV in Europe
Portugal
2. #AIDS2018 | @AIDS_conference | www.aids2018.org
ECDC/EACS Joint Session
Daniel Simões
HIV in Europe Co-chair
Member of the Board @ GAT
Global Public Health PhD fellow @ ISPUP
EATG member
Addressing the first 90: How can HIV testing
more efficiently reach those in need to
promote early diagnosis?
July 23, 2018
3. #AIDS2018 | @AIDS_conference | www.aids2018.org
Disclosure of interest
• Represented GAT at World Hepatitis Summit,
in 2017 with a travel sponsorship from Abbvie
• Represented GAT at Abbvie’s Global HCV
Advisory Board in 2018 (fee was payed to GAT)
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Introductory remarks
• Much has been done; more is needed.
• E/CA are not the world – do not forget the rest of
the world!
• We have to link and learn with each other;
• Strong progress in some parts of the region on
the first 90.
• 90-90-90 is not a magical indicator of success: we
need to understand what it means, what it says
and what it does not say.
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Data availability on the continuum of care
2014 (n=40); 2016 (n=44); 2018 (n=43)
Source: ECDC. Dublin Declaration monitoring 2018; validated unpublished data.
11
25
37
35
26
16
4
37
42
41
31
29
9
41
42 42
37
34
0
10
20
30
40
50
No data PLHIV Diagnosed On ART Viral suppression All stages
Nrofcountriesreportingdata
2014 2016 2018
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Progress toward achieving the first 90:
Target 1: 90% of all PLHIV who know their status (n=39)
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
Centre 83%
West 86%
East 76%
Source: ECDC. Dublin Declaration monitoring 2018; validated unpublished data.
*Latest available data reported, ranging from 2014-2017.
Estimated #
PLHIV (1)
% Diagnosed
(2)
Estimated
undiagnosed
number
Missing
Diagnoses per
100.000 (3)
Portugal 38959 92% 3234 31,4
Sweden 7718 90% 772 7,6
Greece 14200 89% 1420 13,1
Romania 14000 88% 1680 8,4
Belgium 11774 83% 2001 17,6
Spain 141000 82% 25380 54,6
Croatia 1680 70% 504 11,8
1: Source: European Centre for Disease Prevention and Control. Thematic report: Continuum of HIV care. Monitoring
implementation of the Dublin Declaration on Partnership to Fight HIV/AIDS in Europe and Central Asia: 2017 progress report.
Stockholm: ECDC; 2017
2: Source: ECDC. Dublin Declaration monitoring 2018; validated unpublished data.
3: Population estimate source: https://en.wikipedia.org/wiki/List_of_European_countries_by_population
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Ticking the boxes
• Diagnosis has to be a system of responses. It is about giving
people choices they are comfortable with to get tested.
• A series of boxes have to be ticked – with good monitoring:
– Indicator conditions,
- Pregnant women,
- PICT on geographical hotspots,
- Community located AND community participated VCT
adjusted to your epidemics,
- Self testing/Self sampling,
- Partner notification and contact tracing
– Responses for those out of the box – specific services for
specific needs (mind the overlaps – chemsex and HR)
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Are new innovative approaches to HIV testing
included in national HIV testing guidelines? (n=55)
Testing approaches Yes No
No
response
Community-based testing delivered by
trained medical staff
28 12 15
Community-based testing delivered by non-
medical staff (e.g. trained lay people)
14 26 15
Home-sampling kits 4 36 15
Self-testing kits 9 32 14
Source: Dublin Declaration monitoring 2018; validated unpublished data.
Up from 2
in 2017
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Implementation of community-based testing by trained
medical staff in Europe and Central Asia, 2018
Source: ECDC. Dublin Declaration monitoring 2018; validated unpublished data.
Implementation of community-based testing by
lay providers in Europe and Central Asia, 2018
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Implementation of self-testing in
Europe and Central Asia, 2018
Source: ECDC. Dublin Declaration monitoring 2018; validated unpublished data.
Implementation of self-sampling in Europe
and Central Asia, 2018
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Keep in mind
• We need to give people choices (how to test, where to test,
who tests);
• Meaningful participation is crucial!
• Health is our priority but it is not the priority of many people
due to circumstances of life - Social determinants;
• Integration – other diseases (HCV, HBV, STI, TB), other
responses, other stakeholders
• People are not as square as boxes (most people at least) – We
need tailored responses;
• End repression, stigma and discrimination.
Source: Portuguese Community Based Screening Network data, 2016-2017 (unpublished data).Source Portuguese Community Based Screening Network data, 2016-2017 (unpublished data).
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>50%
30 to <40%
<30%
Missing data or did
not report
Luxembourg
Malta
Non-visible countries
Late diagnosis, 2016, EU/EEA
% persons with CD4
<350 cells/mm3 at HIV diagnosis
40 to <50%
Source: ECDC/WHO (2017). HIV/AIDS Surveillance in Europe 2017– 2016 data
• EU/EEA Average: 48%
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Comparison of the continuum of care for key
populations, 2018
100%
86%
78% 75%
100%
90%
50%
39%
100%
84%
75% 71%
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
Living with
HIV
Diagnosed Receiving
ART
Virally
suppressed
Living with
HIV
Diagnosed Receiving
ART
Virally
suppressed
Living with
HIV
Diagnosed Receiving
ART
Virally
suppressed
MSM (n=10) PWID (n=8) Migrants (n=5)
Source: ECDC. Dublin Declaration monitoring 2018; validated unpublished data.
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Comparison of the continuum of care for key
populations against national continua, 2018
100%
86%
78% 75%
100%
90%
50%
39%
100%
84%
75% 71%
100%
87%
77%
70%
100%
86%
75%
67%
100%
88%
81%
76%
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
Living with
HIV
Diagnosed Receiving
ART
Virally
suppressed
Living with
HIV
Diagnosed Receiving
ART
Virally
suppressed
Living with
HIV
Diagnosed Receiving
ART
Virally
suppressed
MSM (n=10) PWID (n=8) Migrants (n=5)
Source: ECDC. Dublin Declaration monitoring 2018; validated unpublished data.
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In sum…
• End legal and social repression and stigma;
• Know your epidemics to design your responses;
• Information and literacy are crucial;
• Give people choices of where to go where they feel
good, and that respond to their needs;
• Tick the boxes and remember: one size does not fit all;
• Many things have been tried: look up results and speak
to who did them;
• Involve communities every step of the way!
• However…
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Are sufficient funds available for HIV prevention to decrease the
number of new infections in your country? 2018
Source: ECDC. Dublin Declaration monitoring 2018; validated unpublished data.
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Closing remarks
(1)2 years to go
Harder, Better, Faster, Stronger
Daft Punk, 2001
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Acknowledgments
• ECDC Dublin team, especially Teymur Noori
• Luís Mendão @GATVIH
• The Community Based Screening Network
team in Portugal
• HIV in Europe team