This document discusses upscaling thermal-hydrological-mechanical (THM) parameters from sample to repository scale when modeling radioactive waste disposal. It summarizes two in situ heating experiments performed in Callovo-Oxfordian claystone at the Bure underground research laboratory in France: a borehole heater test and a full-scale demonstration experiment. Modeling results of the borehole experiment show good agreement with measured temperature and pressure data. The next steps are to complete modeling of the borehole test and begin modeling the full-scale experiment using calibrated THM parameters to predict repository-scale behavior.