20080516 Spontaneous separation of bi-stable biochemical systems

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The document discusses bi-stable biochemical systems that can spontaneously separate into spatial domains with opposite states due to stochastic fluctuations, even within small volumes like bacteria. It introduces the Next Subvolume Method for simulating these systems by partitioning volumes into well-mixed subvolumes and accounting for diffusion between them. Shape, diffusion rates, and geometry can influence whether and where spatial separation occurs.

Spontaneous separation of bi-stable biochemical systems into spatial domains of opposite phases Johan Elf and Måns Ehrenberg Presented by Jonathan Blakes Computational Foundations of Nanoscience Journal Club 2008-05-16

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