This document discusses inquiry-based learning and science education. It describes inquiry as a multifaceted process involving questioning, experimenting, data collection, and more. Different levels of inquiry are presented, ranging from teacher-centered closed inquiry to open inquiry driven by students. The Web-based Inquiry Science Environment (WISE) is introduced as a platform to support scaffolded inquiry through online science curriculum and assessments. Several other digital learning games and environments that employ inquiry approaches are also listed.