eNre automates the process of patient engagement and recruitment. Clinical Research sites today are looking at efficient and automated ways to increase research efficiency. eNre helps the principal investigator and all the involved stakeholders better manage trials so that they can spend most of their time in core research

1. Persistent InteractiveeNre – Engage and Recruit
Automate patient engagement and recruitment in clinical trials
Engage. Recruit
Harshal Shah
408.477.5654

2. © 2017 eNRE Inc H Shah
ACA : $200B PCORI : $4B PCORNET : $250M
13 CDRNs
70+ Million Patients
REACHNet : $14M so far
5+ Health Systems
4+ Million Patients
The Birth Journey

3. © 2017 eNRE Inc H Shah
- Search electronic medical records
- Check schedule
- Meet patients
Site Approach:
Dave Fox, MD, PhD
Goal:
Recruit 1,000 patients in 2 years
Goal:
PharmCo
3
The Problem

4. © 2017 eNRE Inc H Shah
2/3
Misses
recruitment
goals!!
- Manual
- Resource intensive
- Intrusive in nature
Problem:
4
2 Year Later….

5. © 2017 eNRE Inc H Shah
Clinical trials still uses traditional technologies like TV
advertisements, paper-based forms for patient recruitment.

6. © 2017 eNRE Inc H Shah
It is no surprise sites miss their enrollment numbers!

7. © 2017 eNRE Inc H Shah
Investigators today are looking for…
Faster Recruitment Cost Effective Automated Researcher Friendly

8. © 2017 eNRE Inc H Shah
Trial sites today are looking for…
Faster recruitment
Faster Recruitment
1 day of delay in drug development costs $37,000
in operational costs and $1,100,000 in opportunity
costs
eNre helped recruit 5000+ patients in 12 months
vs 400+ over 48 months for similar study in
similar region
Reference:
• http://www.tandfonline.com/doi/abs/10.3109/02770909909075405
• https://www.priv.gc.ca/media/sp-d/2014/sp-d_20141020_pk_e.asp.

9. © 2017 eNRE Inc H Shah
Trial sites today are looking for…
Faster recruitment
Traditional recruitment involves billboard
advertisement, TV advertisement, recruiters
onboarding and is a costly affair
eNre can save $1,025,000 vs. traditional
recruitment alternative **
Cost Effective
Reference:
• Billboard advertising. BlueLineMedia website. Available at: http://www.bluelinemedia.com/billboard-advertising.
• Wagner N. How much does television advertising really cost? Houston Chronicle website.
Available at: http://smallbusiness.chron.com/much-television-advertising-really-cost-58718.html.

10. © 2017 eNRE Inc H Shah
Trial sites today are looking for…
Faster recruitment
Three-quarters (72%) of Americans say it’s likely
they would participate in a clinical trial if
recommended by their doctor
eNre provides intuitive, involved and engaged
recruitment workflow with physician and
researcher friendly tools to increase participation
Researcher
Friendly
Reference:
https://www.elsevier.com/connect/poll-majority-of-americans-would-participate-in-clinical-trials-ifrecommended-
by-doctor.

11. © 2017 eNRE Inc H Shah
Trial sites today are looking for…
Faster recruitment
Intrusive, manual and unclear techniques reduce
trial participation. 40% of adults do not
understand trials.
By qualifying participants through EMR
intelligence, streamlined non-intrusive workflow
and video based overview eNre automates for
efficient recruitment.
Automated
Reference:
http://ascopubs.org/doi/full/10.1200/jco.2003.02.105

12. © 2017 eNRE Inc H Shah
eNre connects patients/participants seamlessly to trials
leveraging technology solution in and out of the clinic
settings for efficient trials recruitment
Engage. Recruit
eNre : Automating trials recruitment and engagement

13. © 2017 eNRE Inc H Shah
Before - After
Trial
Initiation
Search EMR
records
Find Eligible
patients
Hire
Recruiters
Checking
Clinic
Schedule
Talk to
Patient
Manual
consent
Track
consented
patients
Manual
follow-up
Lose
Funding
Trial
Initiation
Deploy
eNre
Find Eligible
patients
Hire
Recruiters
Checking
Clinic
Schedule
Talk to
Patient
e-consent
Track
consented
patients
Automate
follow-up
Next Trial

14. © 2017 eNRE Inc H Shah
Suite of products to automate recruitment
Flags eligible patients (query)
Syncs to patient (automated)
Recruits patient (safe space)
Engages patient (web/mobile)
eNquire
eNgage
eNlist
eNre suite of products are set to ease onboarding…

15. © 2017 eNRE Inc H Shah
Features
EMR
Integration
Cohort
Builder
POC
Recruitment
Engagement
Tools
Workflow
Widgets
Physician
Influence
Researcher
Dashboard
Patient
Registry
E-Consent
capability
PRO capture
capability
All you always wanted but could not get…

16. © 2017 eNRE Inc H Shah
eNre
How the eNre Platform Works
16
SponsorSite
Clinical
Data
Firewall
EMR
Exam Room
Anonymously connects to clinical data.
No data leaves the health system.
Deliver content to patients in exam rooms
or to their personal devices and social networks
Select eligible patients
based on trial criteria
1
3
2
Let us deep dive into the backend…

17. © 2017 eNRE Inc H Shah
ConsentInformational Video Contact Information
Sample : Registry Recruitment
Pre-screening Questions

18. © 2017 eNRE Inc H Shah
Sample : Trial Recruitment
Informational Video Pre-screening Questions Contact Information
Do you currently take
aspirin daily?

19. © 2017 eNRE Inc H Shah
Sample : Recruitment Dashboard

20. 20
Text Messages
Visit www.adaptablepatient.com to learn more and enroll.
Your personal access code for ADAPTABLE is: ${accessCode}
Questions about ADAPTABLE? Call Ochsner 1-844-816-0297
Email / text message with ADAPTABLE link,
patient’s unique access code, and CRC contact info
for future reference are sent to patients
Sample : Engagement Follow-up

21. © 2017 eNRE Inc H Shah
Quick Sample of Tools: Command CenterSample : Command Center

22. © 2017 eNRE Inc H Shah
4 Million+ Patients 4+ Health Systems 30+ Clinics
WeighSmart Study
5,000 patients recruited within a year
Current Deployments

23. © 2017 eNRE Inc H Shah
Next Steps

24. Persistent Interactive
Thank You
Contact :
Harshal Shah
408.477.5654