Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.
Alkaloids in Fungi        Rayeess Ahmad Dar         MSc. Bioresources           Semester 3rd          Roll No. 23352      ...
AlkaloidsAlkaloids are the cyclic organic compoundsin which nitrogen forms a part of the cyclesystem and are physiological...
   Alkaloids are mostly produced by plants.   However, some are derived from bacteria,    fungi, animals.   Synthesized...
Classification   1. True (Typical Alkaloids): Derived from amino    acids and have nitrogen in a heterocyclic ring.    At...
Main Functions   They act as protective agents against insects,    herbivores due to their bitterness and toxicity.    So...
Some of the Alkaloids present in             Fungi
Alkaloids From Ergot Fungi   Ergot fungi belong to the Claviceps genera.   These fungi affect rye (mostly), wheat, barle...
Ergotamine   It has the biological activity as a    vasoconstrictor.   It is used medicinally for the treatment of    ac...
   Methergin is the brand name of    the drug that has been derived    from Ergot and is used to stop    post natal bleed...
ergotamine             Ergot on rye
   However, high doses of ergot alkaloids or    taking the infected grains lead to Ergotism.   It is characterized by sp...
Loline alkaloids   These are insecticidal and insect-deterrent    compounds.   These are produced in grasses infected by...
Psilocybin   Produced by about 200 species of mushrooms    collectively called psilocybin mushrooms (such as    Psilocybe...
Psilocybe azurescens - Flying   Psilocybe cyanescensSaucers
Oxaline   Derived from Penicillium oxalicum, which    usually grows on dead and decaying matter.   This alkaloid was fou...
Penicillium rot caused by Penicillium oxalicum in thecorn
Paramine   Produced by some grass infecting    Neotyphodium species.   The alkaloid protects the grass againest    grazi...
Upcoming SlideShare
Loading in …5
×

Alkaloids in fungi

2,999 views

Published on

  • Be the first to comment

Alkaloids in fungi

  1. 1. Alkaloids in Fungi Rayeess Ahmad Dar MSc. Bioresources Semester 3rd Roll No. 23352 University of Kashmir Hazratbal Srinagar
  2. 2. AlkaloidsAlkaloids are the cyclic organic compoundsin which nitrogen forms a part of the cyclesystem and are physiologically active aspoisons and drugs.
  3. 3.  Alkaloids are mostly produced by plants. However, some are derived from bacteria, fungi, animals. Synthesized from amino acids.
  4. 4. Classification 1. True (Typical Alkaloids): Derived from amino acids and have nitrogen in a heterocyclic ring. Atropine. 2. Protoalkaloids: Derived from amino acids and do not have nitrogen in a heterocyclic ring. Ephedrine. 3. Pseudo alkaloids: Not derived from amino acids but have nitrogen in a heterocyclic ring. Caffeine. 4. False alkaloids: Non alkaloids which give false positive reaction with alkaloidal reagents.
  5. 5. Main Functions They act as protective agents against insects, herbivores due to their bitterness and toxicity. So, they can be used as biopesticides and bioinsecticides. They also act as a source of nitrogen in case of nitrogen deficiency. Many of them have medicinal properties.
  6. 6. Some of the Alkaloids present in Fungi
  7. 7. Alkaloids From Ergot Fungi Ergot fungi belong to the Claviceps genera. These fungi affect rye (mostly), wheat, barley. The fungi produce alkaloids such as Ergotamine, Ergometrine, Ergonaline and various other Clavine alkaloids. Has the biological activity as vasoconstrictors.
  8. 8. Ergotamine It has the biological activity as a vasoconstrictor. It is used medicinally for the treatment of acute migrain attacks (sometimes in combination with caffeine). It has been used to prevent post-partum hemorrhage (bleeding after child birth). It was first isolated by Arthur Stoll in 1918.
  9. 9.  Methergin is the brand name of the drug that has been derived from Ergot and is used to stop post natal bleeding
  10. 10. ergotamine Ergot on rye
  11. 11.  However, high doses of ergot alkaloids or taking the infected grains lead to Ergotism. It is characterized by spasms, diarrhea, head aches, vomiting etc.
  12. 12. Loline alkaloids These are insecticidal and insect-deterrent compounds. These are produced in grasses infected by endophytic fungal symbionts of the genus Epichloe and Neotyphodium. First isolated from the grass Lolium temulentum.
  13. 13. Psilocybin Produced by about 200 species of mushrooms collectively called psilocybin mushrooms (such as Psilocybe azurescens, P. cyanescens and a number of other genera). When ingested, psilocybin is turned into psilocin within the body, which in turn is responsible for hallucinations, changes in perception, a distorted sense of time and can include possible adverse reactions such as nausea and panic attacks.
  14. 14. Psilocybe azurescens - Flying Psilocybe cyanescensSaucers
  15. 15. Oxaline Derived from Penicillium oxalicum, which usually grows on dead and decaying matter. This alkaloid was found to arrest the cell cycle by inhibition of tubulin polymerisation.
  16. 16. Penicillium rot caused by Penicillium oxalicum in thecorn
  17. 17. Paramine Produced by some grass infecting Neotyphodium species. The alkaloid protects the grass againest grazing by mammals and insects. This alkaloid can also be used as bioinsecticide and biopesticide.

×