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PNEUMONIA
PRESENTED BY
GROUP NO # 3
INTRODUCTION
 Pneumonia is an infection in one or both of your lungs.
 Pneumonia is an inflammation of the parenchyma of the
lung.
 Characterized primarily by inflammation of the alveoli in the
lungs .
 Most cases of pneuomina are caused by
microorganism.
 non infectious causes
 Include aspiration of food
 Gastric acid foreign bodies
hydrocarbons and lipid substances
hypersensitivity reaction.
 Drug or radiation induced pneumonitis.
TYPES OF
PNEUMONIA
TYPES OF PNEUMONIA…
ANATOMICAL
CLASSIFICATION
Bronchial
pneumonia
lobar pneumonia
1. LOBAR PNEUMONIA :-
it affects a section (lobe) of a lung.
 Bronchial pneumonia (Bronchopneumonia)
:-
It affects patches throughout both lungs.
COMMUNITY –ACQUIRED
PNEUMONIA
 Community-acquired pneumonia develops in
people with limited or no contact with medical
institution. The most commonly identified
pathogens are Streptococcus pneumoniae,
Haemophilus influenzae, atypical bacteria and
viruses.
 Symptoms and signs are fever, cough, sputum
production, pleuritic chest pain, dyspnea,
tachypnea, and tachycardia.
 Diagnosis is based on clinical presentation and
chest x-ray. Treatment is with empirically chosen
antibiotics
SIGNS AND SYMPTOMS
SIGN AND SYMPTOMS
 High fever, Shaking Chills
 Shortness of breath (Dyspnea)
 Increased breathing rate
 Chest pain when you breathe deeply or cough
 Dusky or purplish skin color (cyanosis) from poorly
oxygenated blood
 Fatigue and muscle aches
 Nausea, vomiting or diarrhea.
 Cough, particularly cough productive of sputum
ETIOLOGY
 BACTERIAL INFECTION
 streptococcus pneumoniae
Group B streptococci
Group A streptococci
 Mycoplasma pneumoniae
 chlamydia pneumoniae
 chlamydia trachomatis
 Mixed anaerobes
 Gram-negative enteric.
 VIRAL INFECTION
 Adenoviridae (adenoviruses)
 Coronaviridae (coronaviruses)
 Bunyaviridae (arboviruses) -Hantavirus
 Orthomyxoviridae (orthomyxoviruses) - Influenza virus
 Papovaviridae (polyomavirus)
 FUNGAL INFECTION
 Histoplasma capsulatum
 Cryptococcus neoformans .
 Aspergillus species .
 Mucomycosis .
 Coccidioides immitis.
 Blastomyces dermatitides .
MYCOBACTERIAL INFECTION
Mycobacterium Tuberculosis
Mycobacterium avium-inteacellulare.
CAUSATIVE AGENTS IN
DIFFERENT AGE GROUPS
DIAGNOSIS
 Chest x-ray
 Blood test
 Pulse oximetry
 Bronchoscopy
 Sputum test
through sputum test we analyze in following
ways :-
 Streptococcus pneumoniae: Rust-colored sputum
 Pseudomonas, Haemophilus, and pneumococcal
species: May produce green sputum
 Klebsiella species pneumonia: Red currant-jelly sputum
 Anaerobic infections: Often produce foul-smelling or
bad-tasting sputum
 Newborns and infants may not show any sign of the
infection. Or they may vomit, have a fever and cough,
appear restless or tired and without energy, or have
difficulty breathing and eating
 Older people who have pneumonia sometimes have
sudden changes in mental awareness.
COMPLICATIONS
 Bacteria in the bloodstream (bacteremia)
 Lung abscess.
 Build up of fluid in the space between the lung
and chest wall (pleural effusion).
 Difficulty breathing.
 Shock and respiratory failure
 Septic arthritis
 Endocarditis
TREATMENT
 Most people can be treated at home.
 If pneumonia becomes so severe that treatment is
in the hospital, you may receive fluids and
antibiotics in your veins, oxygen therapy, and
possibly breathing treatments.
GOALS OF THERAPY
 Eradication of the offending organism.
 Selection of an appropriate antibiotic.
 To minimize associated morbidity.
GENERAL APPROACH TO
TREATMENT
 Adequacy of respiratory function
 Humidified oxygen for hypoxemia
 Bronchodilators (albuterol)
 Chest physiotherapy with postural drainage
 Adequate hydration if necessary
 Expectorants such as guaifenesin
 Chest pain- analgesics
BACTERIAL PNEUMONIA
 Selection of an antimicrobial agent
 Empirical use of relatively broad spectrum antibiotic
 Narrow spectrum antibiotics to cover specific
pathogen
 Potential pathogens involved
 Age
 Previous &current medication history
 Underlying disease
 Present clinical status
ANTIOBIOTICS
 Penicillin: common penicillin used to treat pneumonia-
 Amoxicillin (AMOXIL)
 amoxicillin clavulanate (Augmentin)
 Ampicillin (Rimacillin)
 Benzylpenicillin (Crystapen)
 Piperacillin-tazobactam (Tazocin)
 Ticarcillin-clavulnate (Timentin).
 There is a risk of a type of jaundice if you take
amoxicillin clavulanate (affects liver function)
 Macrolides:
 Often prescribed. Interference with other medicines.
 Stomach cramps and can damage liver if taken for long time.
 Common macrolides used are-
 Azithromycin (Zithromax)
 Clarithromycin (Klaricid)
 Erythromycin (Erymax, Erythrocin).
 3. Ceftaroline, a cephalosporin, is newly approved for the
treatment against methicillin-resistant Staphylococcus (S.)
aureus (MRSA) and multidrug-resistant Streptococcus
pneumonia.
Fluoroquinolones
 Ciprofloxacin (Cipro)
 Levofloxacin (levo)
 Gemifloxacin
 Side effects include-
 Nervous system, mental, and heart problems
 Sensitivity to light
 Pregnant women should not take these
medications.
VIRAL PNEUMONIA
 Viral pneumonias – when viruses are etiological
agents
 Viral pneumonia Mild and self-limited illness to a
Life-threatening disease
 Four Most commom viruses encountered
 Influenza virus
 Respiratory syncytial virus (RSV)
 Adenovirus
 Parainfluenza virus
TREATMENT
MANAGEMENT OF PNEUMONIA
 Don't smoke.
 Practice good hygiene.
 Stay rested and fit.
 Wearing surgical masks by the sick may also
prevent illness.
 Appropriately treating underlying illnesses
(such as HIV/AIDS, diabetes mellitus, and
malnutrition) can decrease the risk of
pneumonia.
 Get a Pneumonia Vaccination.
VACCINATION
 Pneumococcal conjugate vaccine
(Prevnar):
For children less than 2 years of age
or between two and four years with certain
medical conditions.
 Pneumococcal polysaccharide vaccine
(Pneumovax) :
Adults who are at increased
risk of developing pneumococcal pneumonia,
such as the elderly, diabetics, those with
chronic heart, lung, or kidney disease,
alcoholics, smokers, and those without a
spleen.
Pneumonia

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Pneumonia

  • 2. INTRODUCTION  Pneumonia is an infection in one or both of your lungs.  Pneumonia is an inflammation of the parenchyma of the lung.  Characterized primarily by inflammation of the alveoli in the lungs .
  • 3.  Most cases of pneuomina are caused by microorganism.  non infectious causes  Include aspiration of food  Gastric acid foreign bodies hydrocarbons and lipid substances hypersensitivity reaction.  Drug or radiation induced pneumonitis.
  • 6. 1. LOBAR PNEUMONIA :- it affects a section (lobe) of a lung.
  • 7.  Bronchial pneumonia (Bronchopneumonia) :- It affects patches throughout both lungs.
  • 8. COMMUNITY –ACQUIRED PNEUMONIA  Community-acquired pneumonia develops in people with limited or no contact with medical institution. The most commonly identified pathogens are Streptococcus pneumoniae, Haemophilus influenzae, atypical bacteria and viruses.  Symptoms and signs are fever, cough, sputum production, pleuritic chest pain, dyspnea, tachypnea, and tachycardia.  Diagnosis is based on clinical presentation and chest x-ray. Treatment is with empirically chosen antibiotics
  • 10. SIGN AND SYMPTOMS  High fever, Shaking Chills  Shortness of breath (Dyspnea)  Increased breathing rate  Chest pain when you breathe deeply or cough  Dusky or purplish skin color (cyanosis) from poorly oxygenated blood  Fatigue and muscle aches  Nausea, vomiting or diarrhea.  Cough, particularly cough productive of sputum
  • 11. ETIOLOGY  BACTERIAL INFECTION  streptococcus pneumoniae Group B streptococci Group A streptococci  Mycoplasma pneumoniae  chlamydia pneumoniae  chlamydia trachomatis  Mixed anaerobes  Gram-negative enteric.
  • 12.  VIRAL INFECTION  Adenoviridae (adenoviruses)  Coronaviridae (coronaviruses)  Bunyaviridae (arboviruses) -Hantavirus  Orthomyxoviridae (orthomyxoviruses) - Influenza virus  Papovaviridae (polyomavirus)  FUNGAL INFECTION  Histoplasma capsulatum  Cryptococcus neoformans .  Aspergillus species .  Mucomycosis .  Coccidioides immitis.  Blastomyces dermatitides . MYCOBACTERIAL INFECTION Mycobacterium Tuberculosis Mycobacterium avium-inteacellulare.
  • 14. DIAGNOSIS  Chest x-ray  Blood test  Pulse oximetry  Bronchoscopy  Sputum test through sputum test we analyze in following ways :-
  • 15.  Streptococcus pneumoniae: Rust-colored sputum  Pseudomonas, Haemophilus, and pneumococcal species: May produce green sputum  Klebsiella species pneumonia: Red currant-jelly sputum  Anaerobic infections: Often produce foul-smelling or bad-tasting sputum  Newborns and infants may not show any sign of the infection. Or they may vomit, have a fever and cough, appear restless or tired and without energy, or have difficulty breathing and eating  Older people who have pneumonia sometimes have sudden changes in mental awareness.
  • 16. COMPLICATIONS  Bacteria in the bloodstream (bacteremia)  Lung abscess.  Build up of fluid in the space between the lung and chest wall (pleural effusion).  Difficulty breathing.  Shock and respiratory failure  Septic arthritis  Endocarditis
  • 17. TREATMENT  Most people can be treated at home.  If pneumonia becomes so severe that treatment is in the hospital, you may receive fluids and antibiotics in your veins, oxygen therapy, and possibly breathing treatments.
  • 18. GOALS OF THERAPY  Eradication of the offending organism.  Selection of an appropriate antibiotic.  To minimize associated morbidity.
  • 19. GENERAL APPROACH TO TREATMENT  Adequacy of respiratory function  Humidified oxygen for hypoxemia  Bronchodilators (albuterol)  Chest physiotherapy with postural drainage  Adequate hydration if necessary  Expectorants such as guaifenesin  Chest pain- analgesics
  • 20. BACTERIAL PNEUMONIA  Selection of an antimicrobial agent  Empirical use of relatively broad spectrum antibiotic  Narrow spectrum antibiotics to cover specific pathogen  Potential pathogens involved  Age  Previous &current medication history  Underlying disease  Present clinical status
  • 21.
  • 22. ANTIOBIOTICS  Penicillin: common penicillin used to treat pneumonia-  Amoxicillin (AMOXIL)  amoxicillin clavulanate (Augmentin)  Ampicillin (Rimacillin)  Benzylpenicillin (Crystapen)  Piperacillin-tazobactam (Tazocin)  Ticarcillin-clavulnate (Timentin).  There is a risk of a type of jaundice if you take amoxicillin clavulanate (affects liver function)
  • 23.  Macrolides:  Often prescribed. Interference with other medicines.  Stomach cramps and can damage liver if taken for long time.  Common macrolides used are-  Azithromycin (Zithromax)  Clarithromycin (Klaricid)  Erythromycin (Erymax, Erythrocin).  3. Ceftaroline, a cephalosporin, is newly approved for the treatment against methicillin-resistant Staphylococcus (S.) aureus (MRSA) and multidrug-resistant Streptococcus pneumonia.
  • 24. Fluoroquinolones  Ciprofloxacin (Cipro)  Levofloxacin (levo)  Gemifloxacin  Side effects include-  Nervous system, mental, and heart problems  Sensitivity to light  Pregnant women should not take these medications.
  • 25. VIRAL PNEUMONIA  Viral pneumonias – when viruses are etiological agents  Viral pneumonia Mild and self-limited illness to a Life-threatening disease  Four Most commom viruses encountered  Influenza virus  Respiratory syncytial virus (RSV)  Adenovirus  Parainfluenza virus
  • 27.
  • 28. MANAGEMENT OF PNEUMONIA  Don't smoke.  Practice good hygiene.  Stay rested and fit.  Wearing surgical masks by the sick may also prevent illness.  Appropriately treating underlying illnesses (such as HIV/AIDS, diabetes mellitus, and malnutrition) can decrease the risk of pneumonia.  Get a Pneumonia Vaccination.
  • 29. VACCINATION  Pneumococcal conjugate vaccine (Prevnar): For children less than 2 years of age or between two and four years with certain medical conditions.  Pneumococcal polysaccharide vaccine (Pneumovax) : Adults who are at increased risk of developing pneumococcal pneumonia, such as the elderly, diabetics, those with chronic heart, lung, or kidney disease, alcoholics, smokers, and those without a spleen.