Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.
ILD & OLD
Interstitial & Occupational
lung diseases
Interstitial lung disease
 Heterogenous group of diseases,
characterized by diffuse involvement of
interstitium
 Insidio...
Manifestation
 Clinical-
 Dry cough, progressive dyspnea
 h/o exposure to dust/fumes or of CTD
 Clubbing
 End-inspira...
Radiological appearance
Diagnosis
Bronchoalveolar lavage
Transbronchial biopsy
Surgical lung biopsy- VATS/open
Idiopathic fibrosing interstitial pneumonia
 Formerly idiopathic pulmonary fibrosis
 R/O any underlying cause
 Patterns...
Occupational lung disease
 Due to inhalation of noxious substances in
workplace
 Types-
 Pneumoconiosis- coal workers, ...
Pneumoconiosis
 Chronic fibrotic lung diseases caused by
inhalation of coal or other inorganic
or silicate dusts
 Manife...
Coal-worker’s
pneumoconiosis
 Ingestion of inhaled coal dust by
macrophageschronic inflammation fibrosis
 Common in up...
Silicosis
 Silicon dioxide particle inhalation
couses small rounded opacities in lung
 Associated with eggshell calcific...
Asbestosis
 Nodular interstitial fibrosis in persons
chronically exposed to asbestos fibres
 Associated with pleural cal...
Upcoming SlideShare
Loading in …5
×

Interstitial and occupational lung disease

1,427 views

Published on

  • Be the first to comment

Interstitial and occupational lung disease

  1. 1. ILD & OLD Interstitial & Occupational lung diseases
  2. 2. Interstitial lung disease  Heterogenous group of diseases, characterized by diffuse involvement of interstitium  Insidious onset, chronic course  Alveolitisinterstitial involvementfibrosis  Causes- common  Occupational/environmental exposure  Collagen vascular diseases & vasculitides  Drugs- amiodarone, NFT, bleomycin, busulphan, penicillamine  Idiopathic
  3. 3. Manifestation  Clinical-  Dry cough, progressive dyspnea  h/o exposure to dust/fumes or of CTD  Clubbing  End-inspiratory fine crepts, common at bases  CxR- reticulonodular changeshoneycombing  HRCT- high-resolution CT  PFT-  Restrictive pattern, with decreased DLco  ABG- hypoxemia
  4. 4. Radiological appearance
  5. 5. Diagnosis Bronchoalveolar lavage Transbronchial biopsy Surgical lung biopsy- VATS/open
  6. 6. Idiopathic fibrosing interstitial pneumonia  Formerly idiopathic pulmonary fibrosis  R/O any underlying cause  Patterns-  UIP- usual interstitial pneumonia  RB-ILD- respiratory bronchiolitis associated ILD  AIP- acute interstitial pneumonitis  NSIP- non-specific interstitial pneumonitis  COP- cryptogenic organizing pneumonitis  Rx- steroids, stop smoking, supplemental O2  Finally, lung transplantation
  7. 7. Occupational lung disease  Due to inhalation of noxious substances in workplace  Types-  Pneumoconiosis- coal workers, silicosis, asbestosis, siderosis  Hypersensitivity pneumonitis- farmers, pigeon breeders, bagassosis  Obstructive airway disease- grain/wood/cotton dust  Toxic lung injury- nitrogen oxide  Lung cancer- asbestos, radon gas, arsenic  Pleural disease- asbestos, talc
  8. 8. Pneumoconiosis  Chronic fibrotic lung diseases caused by inhalation of coal or other inorganic or silicate dusts  Manifestation- as in ILD  Dx- exposure + clinical + CxR/HRCT  Rx-  Supportive  Avoid exposure  No smoking
  9. 9. Coal-worker’s pneumoconiosis  Ingestion of inhaled coal dust by macrophageschronic inflammation fibrosis  Common in upper lobes  Caplan syndrome- pulmonary nodules in coal worker with rheumatoid arthritis
  10. 10. Silicosis  Silicon dioxide particle inhalation couses small rounded opacities in lung  Associated with eggshell calcification- calcification of periphery of hilar LN
  11. 11. Asbestosis  Nodular interstitial fibrosis in persons chronically exposed to asbestos fibres  Associated with pleural calcification

×