This document summarizes a case report of a successful ABO-incompatible living donor liver transplantation performed on a patient with a history of platelet transfusion-related anaphylaxis. The patient had hepatitis B virus-related liver cirrhosis and hepatocellular carcinoma. Liver transplantation often requires significant blood loss and transfusions. However, this presented a high risk for the patient due to their previous anaphylactic reaction to platelet transfusions. Despite these risks, the transplantation was performed successfully with no allergic transfusion reactions in the patient.
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2. Case Report
ABO-incompatible living donor liver
transplantation in a patient with a history of
platelet transfusion-related anaphylaxis
Won-Bae Chang, Ho-Seong Han*, Jai Young Cho, Yoo-Seok Yoon, Young
Rok Choi and Bo-Ram Lee
*Corresponding author: Ho-Seong Han, Department of Surgery,
Seoul National University College of Medicine, Seoul National
University, Bundang Hospital, Seongnam, South Korea, 173, 82 Gumi-
ro, Bundang-gu, Seongnam, Gyeonggi, South Korea, 463-707, Tel: 82-
31-787-7091
Dates: Received: 08 April, 2016; Accepted: 28 April, 2016; Published:
30 April, 2016
Citation: Chang WB, Han HS, Cho JY, Yoon YS, Choi YR, et al. (2016)
ABO-incompatible living donor liver transplantation in a patient with
a history of platelet transfusion-related anaphylaxis. Arch Clin
Gastroenterol 2(1): 010-012.
3. Abstract
Anaphylaxis and severe allergic transfusion reactions (ATR)
are uncommon omplications after blood transfusion.
Nevertheless, these complications are associated with very
severe outcomes, such as dyspnea, shock, and death.
Patients with end-stage liver disease who require liver
transplantation have a high tendency for bleeding because
of splenomegaly-induced hrombocytopenia and decreased
production of coagulation factors in the liver. Liver
transplantation is a very long procedure and a significant
perioperative blood loss is highly likely. Therefore,
transfusion of platelets and other blood products is often
necessary. We report a successful ABO-incompatible living
donor liver transplantation in a patient with hepatitis B
virus-related liver cirrhosis and hepatocellular carcinoma
who had a history of platelet transfusion-related d
anaphylaxis.
4. Thank you
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