Clinical and epidemiological profile of patients undergoing total hip arthro...David Sadigursky
Clinical and epidemiological profile of patients undergoing total hip arthroplasty.
Rheumatology and Orthopedic Medicine
Rheumatol Orthop Med, 2017 doi: 10.15761/ROM.1000120
Clinical and epidemiological profile of patients undergoing total hip arthro...David Sadigursky
Clinical and epidemiological profile of patients undergoing total hip arthroplasty.
Rheumatology and Orthopedic Medicine
Rheumatol Orthop Med, 2017 doi: 10.15761/ROM.1000120
Methods: The current clinical study was conducted at Gaza city. It involved 90 patients who were scheduled for coronary angioplasty procedure. The patients were divided into three groups: The first group (n = 30), underwent BMS implantation and received colchicine 0.5 mg twice daily for six months. The second group (n = 30), underwent BMS implantation alone. The third group (n = 30) underwent DES implantation. All the patients were followed up for six months. The primary endpoint was clinical ISR at 6months. Secondary endpoints included Target Vessel Revascularization (TVR) and Stent Thrombosis (ST).
Bactericidal and Sporicidal Activities against Pathogenic Bacteria of Direct ...science journals
The purpose of this investigation was to examine the bactericidal activity of long lifetime ozone water (LLO water) against pathogenic bacteria of medical, veterinary, and public health interest.
Cardiopulmonary Manifestations of Hepatosplenic SchistosomiasisDra. Mônica Lapa
A esquistossomose é uma doença altamente prevalente com 200 milhões de pessoas infectadas. Hipertensão pulmonar
é uma das manifestações pulmonares dessa doença, principalmente em sua apresentação hepatoesplênica. O objetivo disto estudo foi determinar a prevalência de hipertensão pulmonar em pacientes com esquistossomose com hepatopatia hepatoesplênica forma da doença.
Comparison of Infection Episodes in CKD Patients with or without Hemodialysis...ijtsrd
Chronic kidney diseases CKD is a progressive and irreversible deterioration of renal function. Patients with CKD are prone to a variety of infections. Further chronic hemodialysis increases the infections and related morbidity and mortality. The present study was conducted to assess the probability of infection episode in CKD patients in patients with or without haemodialysis. A Cross sectional observational study was conducted with a total 56 patients with CKD. Clinical and biochemical data related to infections were collected from the individual patient records. The results showed that the chills and rigors, increased TLC, and elevated ESR were found to more in CKD patients on chronic haemodialysis. Further, our results suggested that CKD patient population showed increased-risk for the development of lethal sepsis. Hence, identification of the causes of infection and the appropriate treatment based on the severity of symptoms are essential for CKD patients who are on dialysis. Punit Gupta | Swati Sharma | Ashish Deo "Comparison of Infection Episodes in CKD Patients with or without Hemodialysis from Tribal Population" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-1 , December 2018, URL: http://www.ijtsrd.com/papers/ijtsrd19000.pdf
http://www.ijtsrd.com/medicine/other/19000/comparison-of-infection-episodes-in-ckd-patients-with-or-without-hemodialysis-from-tribal-population/punit-gupta
Autologous mononuclear and mesenchymal stromal cells infusion in COPD patients: impact on pulmonary capacity and quality of life in a Phase I randomized clinical trial
This brief paper will help you to understand survival analysis. This type of analysis is important when the time between exposure and event is of clinical interest. The misconception that mortality and survival are interchangeable comes from the lay use of the terms. Learn more and let me know if you have any questions.
Dr. Dean Schraufnagel from the University of Illinois at Chicago presented information about ILD at a Scleroderma Patient Education Conference on Saturday, March 15, 2014 which was hosted by the Scleroderma Foundation, Greater Chicago Chapter.
Statin therapy associated with improved thrombus resolution in patients with ...TÀI LIỆU NGÀNH MAY
Để xem full tài liệu Xin vui long liên hệ page để được hỗ trợ
: https://www.facebook.com/thuvienluanvan01
HOẶC
https://www.facebook.com/garmentspace/
https://www.facebook.com/thuvienluanvan01
https://www.facebook.com/thuvienluanvan01
tai lieu tong hop, thu vien luan van, luan van tong hop, do an chuyen nganh
The mortality rate of perforated peptic ulcer is still high particularly for aged patients and all the existing scoring systems to predict mortality are complicated or based on history taking which is not always reliable for elderly patients. This study’s aim was to develop an easy and applicable scoring system to predict mortality based on hospital admission data.
Methods: The current clinical study was conducted at Gaza city. It involved 90 patients who were scheduled for coronary angioplasty procedure. The patients were divided into three groups: The first group (n = 30), underwent BMS implantation and received colchicine 0.5 mg twice daily for six months. The second group (n = 30), underwent BMS implantation alone. The third group (n = 30) underwent DES implantation. All the patients were followed up for six months. The primary endpoint was clinical ISR at 6months. Secondary endpoints included Target Vessel Revascularization (TVR) and Stent Thrombosis (ST).
Bactericidal and Sporicidal Activities against Pathogenic Bacteria of Direct ...science journals
The purpose of this investigation was to examine the bactericidal activity of long lifetime ozone water (LLO water) against pathogenic bacteria of medical, veterinary, and public health interest.
Cardiopulmonary Manifestations of Hepatosplenic SchistosomiasisDra. Mônica Lapa
A esquistossomose é uma doença altamente prevalente com 200 milhões de pessoas infectadas. Hipertensão pulmonar
é uma das manifestações pulmonares dessa doença, principalmente em sua apresentação hepatoesplênica. O objetivo disto estudo foi determinar a prevalência de hipertensão pulmonar em pacientes com esquistossomose com hepatopatia hepatoesplênica forma da doença.
Comparison of Infection Episodes in CKD Patients with or without Hemodialysis...ijtsrd
Chronic kidney diseases CKD is a progressive and irreversible deterioration of renal function. Patients with CKD are prone to a variety of infections. Further chronic hemodialysis increases the infections and related morbidity and mortality. The present study was conducted to assess the probability of infection episode in CKD patients in patients with or without haemodialysis. A Cross sectional observational study was conducted with a total 56 patients with CKD. Clinical and biochemical data related to infections were collected from the individual patient records. The results showed that the chills and rigors, increased TLC, and elevated ESR were found to more in CKD patients on chronic haemodialysis. Further, our results suggested that CKD patient population showed increased-risk for the development of lethal sepsis. Hence, identification of the causes of infection and the appropriate treatment based on the severity of symptoms are essential for CKD patients who are on dialysis. Punit Gupta | Swati Sharma | Ashish Deo "Comparison of Infection Episodes in CKD Patients with or without Hemodialysis from Tribal Population" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-1 , December 2018, URL: http://www.ijtsrd.com/papers/ijtsrd19000.pdf
http://www.ijtsrd.com/medicine/other/19000/comparison-of-infection-episodes-in-ckd-patients-with-or-without-hemodialysis-from-tribal-population/punit-gupta
Autologous mononuclear and mesenchymal stromal cells infusion in COPD patients: impact on pulmonary capacity and quality of life in a Phase I randomized clinical trial
This brief paper will help you to understand survival analysis. This type of analysis is important when the time between exposure and event is of clinical interest. The misconception that mortality and survival are interchangeable comes from the lay use of the terms. Learn more and let me know if you have any questions.
Dr. Dean Schraufnagel from the University of Illinois at Chicago presented information about ILD at a Scleroderma Patient Education Conference on Saturday, March 15, 2014 which was hosted by the Scleroderma Foundation, Greater Chicago Chapter.
Statin therapy associated with improved thrombus resolution in patients with ...TÀI LIỆU NGÀNH MAY
Để xem full tài liệu Xin vui long liên hệ page để được hỗ trợ
: https://www.facebook.com/thuvienluanvan01
HOẶC
https://www.facebook.com/garmentspace/
https://www.facebook.com/thuvienluanvan01
https://www.facebook.com/thuvienluanvan01
tai lieu tong hop, thu vien luan van, luan van tong hop, do an chuyen nganh
The mortality rate of perforated peptic ulcer is still high particularly for aged patients and all the existing scoring systems to predict mortality are complicated or based on history taking which is not always reliable for elderly patients. This study’s aim was to develop an easy and applicable scoring system to predict mortality based on hospital admission data.
Total and Cause-Specific Mortality of U.S. Nurses Working Rotating Night ShiftsEmergency Live
Know more on http://www.emergency-live.com
Total and Cause-Specific Mortality of U.S.
Nurses Working Rotating Night Shifts
Fangyi Gu, MD, ScD, Jiali Han, PhD, Francine Laden, ScD, An Pan, PhD, Neil E. Caporaso, MD,
Meir J. Stampfer, MD, DrPH, Ichiro Kawachi, MD, PhD, Kathryn M. Rexrode, MD, MPH,
Walter C. Willett,MD, DrPH, Susan E. Hankinson, ScD, Frank E. Speizer,MD, Eva S. Schernhammer,MD, DrPH
Background: Rotating night shift work imposes circadian strain and is linked to the risk of several
chronic diseases.
Purpose: To examine associations between rotating night shift work and all-cause; cardiovascular
disease (CVD); and cancer mortality in a prospective cohort study of 74,862 registered U.S. nurses
from the Nurses’ Health Study.
Methods: Lifetime rotating night shift work (defined as Z3 nights/month) information was
collected in 1988. During 22 years (1988–2010) of follow-up, 14,181 deaths were documented,
including 3,062 CVD and 5,413 cancer deaths. Cox proportional hazards models estimated
multivariable-adjusted hazard ratios (HRs) and 95% CIs.
Results: All-cause and CVD mortality were significantly increased among women withZ5 years of
rotating night shift work, compared to women who never worked night shifts. Specifically, for
women with 6–14 and Z15 years of rotating night shift work, the HRs were 1.11 (95% CI¼1.06,
1.17) and 1.11 (95% CI¼1.05, 1.18) for all-cause mortality and 1.19 (95% CI¼1.07, 1.33) and 1.23
(95% CI¼1.09, 1.38) for CVD mortality. There was no significant association between rotating night
shift work and all-cancer mortality (HRZ15years¼1.08, 95% CI¼0.98, 1.19) or mortality of any
individual cancer, with the exception of lung cancer (HRZ15years¼1.25, 95% CI¼1.04, 1.51).
Conclusions: Women working rotating night shifts for Z5 years have a modest increase in allcause
and CVD mortality; those working Z15 years of rotating night shift work have a modest
increase in lung cancer mortality. These results add to prior evidence of a potentially detrimental
effect of rotating night shift work on health and longevity.
(Am J Prev Med 2015;](]):]]]–]]]) & 2015 American Journal of Preventive Medicine. All rights reserved.
The Coagulation Profile Monitoring of COVID-19 Patients with Standard and Vis...semualkaira
Coagulation disorders during COVID-19 infection are associated with poor prognosis and disease severity,
because two processes that interfere each other are thrombosis
and inflammation. Very important issue for clinicians is timely
and adequate hemostasis and inflammation monitoring in order to
prevent and treat potentially letal consequences.
The Coagulation Profile Monitoring of COVID-19 Patients with Standard and Vis...semualkaira
Coagulation disorders during COVID-19 infection are associated with poor prognosis and disease severity,
because two processes that interfere each other are thrombosis
and inflammation. Very important issue for clinicians is timely
and adequate hemostasis and inflammation monitoring in order to
prevent and treat potentially letal consequences
The Coagulation Profile Monitoring of COVID-19 Patients with Standard and Vis...semualkaira
Coagulation disorders during COVID-19 infection are associated with poor prognosis and disease severity,
because two processes that interfere each other are thrombosis
and inflammation. Very important issue for clinicians is timely
and adequate hemostasis and inflammation monitoring in order to
prevent and treat potentially letal consequences.
The Coagulation Profile Monitoring of COVID-19 Patients with Standard and Vis...semualkaira
Coagulation disorders during COVID-19 infection are associated with poor prognosis and disease severity,
because two processes that interfere each other are thrombosis
and inflammation. Very important issue for clinicians is timely
and adequate hemostasis and inflammation monitoring in order to
prevent and treat potentially letal consequences.
The Coagulation Profile Monitoring of COVID-19 Patients with Standard and Vis...semualkaira
Coagulation disorders during COVID-19 infection are associated with poor prognosis and disease severity,
because two processes that interfere each other are thrombosis
and inflammation. Very important issue for clinicians is timely
and adequate hemostasis and inflammation monitoring in order to
prevent and treat potentially letal consequences.
The Coagulation Profile Monitoring of COVID-19 Patients with Standard and Vis...semualkaira
Coagulation disorders during COVID-19 infection are associated with poor prognosis and disease severity,
because two processes that interfere each other are thrombosis
and inflammation. Very important issue for clinicians is timely
and adequate hemostasis and inflammation monitoring in order to
prevent and treat potentially letal consequences.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
For Better Surat #ℂall #Girl Service ❤85270-49040❤ Surat #ℂall #Girls
Thrombocytosis at time of hospitalization is a reliable 1
1. Published in: The Egyptian Journal of Chest Diseases and
Tuberculosis. Volume (61), Number (3), July 2012
By:
•Hesham Atef AbdelHalim, Lecturer of chest
diseases, Faculty of medicine, Ain Shams
University.
•Heba Helmy AbdelLatif, Lecturer of chest diseases,
Faculty of medicine, 6th October University.
2. INTRODUCTION
Clinicians have always evaluated the degree of
leukocytosis in patients with pneumonia as an indication of
systemic inflammatory response and severity of disease. But
Platelets have been increasingly recognized as inflammatory
cells with an important role in host defenses.(1)
Few studies investigated the association between
thrombocytosis and clinical outcomes in adult patients with
CAP.(2)
1. Fitzgerald JR, Foster TJ, Cox D. The interaction of bacterial pathogens with platelets. Nat
Rev Microbiol . 2006; 4 (6):445 - 457.
2. Mirsaeidi M, Peyrani P, Aliberti S, Filardo G, Bordon J, Blasi F, and Ramirez JA
Thrombocytopenia and Thrombocytosis at Time of Hospitalization Predict Mortality in
Patients With Community-Acquired Pneumonia CHEST 2010; 137(2):416–420.
3. Objective
Considering that platelets play a crucial role in
antimicrobial host defenses and the coagulation system,
the primary objective of this study was to investigate the
association of an abnormal platelet count as an
important marker to assess severity of disease in patients
with CAP versus the usual counting on the total
leukocyte count.
4. Subjects and methods
• The study was conducted on 66 patients, all had
community acquired pneumonia and all were admitted to
respiratory ICU of Ain Shams University and Ain Shams
University specialized hospitals.
• Data were collected from each patient including,
demographic data, clinical findings, comorbidities,
laboratory data, arterial blood gas results, chest radiographic
findings.
• The collected data were used to calculate the patient’s
pneumonia severity using the pneumonia severity index (PSI)
and CURB-65 (confusion, urea, respiratory rate, blood
pressure, age ≥ 65 years).
• There were no exclusion criteria.
5. RESULTS
Correlations of different data with the parameters
indicating severity on admission (PSI, PSI class, CURB-65
score, length of stay in ICU, mechanical ventilation) were
done using Pearson’s product correlation.
• There were significant correlations between the
following: personal data (age, sex, smoking status), clinical
findings (conscious level, temperature, respiratory rate, heart
rate, systolic and diastolic blood pressure), arterial blood gas
findings (PH, PO2, PO2/FIO2 ratio), laboratory results
(BUN, creatinine, Na, hematocrit, total leucocytic count,
platelet count), radiological findings (distribution in x-ray,
side, loculation of the effusion) and data of severity which are
(PSI, PSI class, CURB-65 score, length of stay in ICU,
mechanical ventilation) (p<0.001).
6. • There were no significant correlation between the
presence of pleural effusion and the parameters of
severity of pneumonia, while albumin level was only
significantly correlated with PSI and PSI class (p<0.05).
• The predictors for severity of community acquired
pneumonia on admission to ICU were examined by
using multiple linear regression models with a
parameter for severity of pneumonia as a dependent
factor for each model; and including all the personal,
clinical, laboratory, arterial blood gas and radiology data
as independent variables.
7. The first multiple linear
regression model used PSI
as a dependent variable, it
was significant (F=857.99,
p= 0.000) and accounts for
99.7% of estimation of
PSI.
The most powerful
predictor was altered
conscious level followed
by platelet count, while
total leucocytic count had
no significant effect.
8. The second linear
regression model used
CURB-65 score as a
dependent variable, it
was significant (F=
273.56, p= 0.000) and
accounts for 99% of
prediction of CURB-65
score.
The most powerful
predictor was platelet
count while TLC was one
of the least significant.
9. The third linear regression
model included
mechanical ventilation as a
dependent variable, the
model was significant (F=
290.18, p= 0.000) and it
explains 99% of the need
for mechanical ventilation.
platelet count was the
most significant
independent factor and
TLC was one of the least
significant in prediction of
the need for mechanical
ventilation
10. The last regression model
used the length of stay in
ICU as a dependent
variable, this model is
significant (F= 123.44, p=
0.000) and it accounts for
97.7% of prediction of the
length of stay in ICU.
in contrast to the previous
models, platelet count has
no significant effect while
the TLC was one of the
most powerful predictors.
11. Conclusion
The initial assessment of a patient with pneumonia,
it is mandatory to consider thrombocytosis as a
predictive factor for severity of pneumonia.
Moreover, when evaluating a complete blood count
report in patients with CAP, platelet count may be more
informative for predicting patient poor outcomes than
the more commonly used leukocyte count.