Hormones of the h HORMONES TARG TRH (thyrotropin releasing hormone) G.pdf

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Hormones of the h HORMONES TARG TRH (thyrotropin releasing hormone) GnRH (gonadotropin releasing hormone) CRH (corticotropin releasing hormone) ANTE GHRH (growth hormone releasing hormone) GLI GHIH (growth hormone release inhibiting hormone or somatostatin (SMS) PRH (prolactin releasing hormone), also called prolactin releasing factor (PRF) PIH (prolactin inhibiting hormone), also called prolactin inhibiting factor. This hormone or factor is dopamine POS oxytocin PIT ADH (Vasopresin) Solution PIH also rarely known as dopamine because normally dopamine is going to release from the arcuate nucleus neurons & secreted into the hypophyseal portal system. The prolactin is released mainly during pregnancy and after pregnancy in the low levels of dopamine. This is because dopamine is the “prolactin inhibiting factor” occasionally known as prolactostatin TRH (thyrotrophic releasing hormone) acts on the thyroid gland to trigger secretions result in homeostasis. GnRH is trophic hormone & it is going to act on the male and female gonads to trigger release of follicle stimulating hormones etc. CRH stimulate corticoids release to bring body homeostasis. Somatostatin (GHIH) inhibits higher gigantism induced due to high growth hormone levels. PRH is going to promote release of prolactin Hypophyseal portal system: Integrated system In terms of portal vessel system, anterior pituitary is connected to the hypothalamus and obtain stimulus (endocrine communication) from hypothalamic parvocellular neurons of central nervous system (CNS) finally release hormones into the hypophyseal portal system. This portal system with blood vessels specifically connects both anterior pituitary and hypothalamus. The hormones released from the adenohypophysis directly enter into the hypophyseal blood stream through capillary beds to reach the target organ. The mechanism of hormone transport through the hypophyseal portal system specifically regulated by the hypothalamic nuclei and these nuclei are the neuronal structures that release neurotransmitters & hormones to stimulate adenohypophysis. In this integrated system, mostly reproductive stimuli are processed at various levels to generate output signal at maturity. In females, multiple integrating centers are existing in hypothalamus to release GnRh to stimulate leutinizing hormone release as output signal onto the female ovarian organs, another integrating center is “neurohyophysis” which releases oxytocin as it receives sensory signal from fetus after complete growth to release “infant” from mother’s womb as part of negative feedback signal on uterus”..

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