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ENDOCRINE SYSTEM
HYPOTHALAMUS
HUMAN ENDOCRINE SYSTEM
WHAT IS HYPOTHALAMUS?
• The portion of the brain that contains a
number of small nuclei with a variety of
functions.
• The control center of all autonomic
regulatory activities of the body.
LOCATION AND STRUCTURE
• It is located in the middle of the base of the brain,
and encapsulates the ventral portion of the third
ventricle.
• A small cone-shaped structure, it projects
downward, ending in the pituitary stalk, a tubular
connection to the pituitary gland.
FUNCTION
• The most important functions of the
hypothalamus is to link the nervous system to
the endocrine system via the pituitary gland.
• It synthesizes and secretes
certain neurohormones, often called
hypothalamic-releasing hormones, and these
in turn stimulate or inhibit the secretion of
pituitary hormones.
ACTION
PITUITARY
GLAND
NEUROHORMONES
• Thyrotrophin- releasing hormone (TRH)
• Corticotrophin-releasing hormone (CRH)
• Gonadotropin-releasing hormone (GnRH)
• Growth hormone-releasing hormone (GHRH)
• Growth hormone-inhibiting hormone
• Prolactin-inhibiting hormone
• Oxytocin
• Vasopressin
NEUROHORMONES
• Hormone ~ Thyrotrophin-releasing
hormone
• Other names ~ Prolactin-releasing hormone
• Symbol(s)~ TRH/TRF/ or PRH
• stimulate thyroid-stimulating hormone (TSH)
release from anterior pituitary hormone
(primarily).
• Stimulate prolactin (PRL) release from
anterior pituitary.
NEUROHORMONES
• Hormone~ Corticotrophin-releasing
hormone
• Symbols (s) ~ CRH/CRF
• Stimulate adrenocorticotrophic hormones
(ACTH) release from anterior pituitary.
NEUROHORMONES
• Hormone~ Gonadotropin-releasing
hormone
• Symbols (s) ~ GnRH/ LHRH
• Stimulating follicle-stimulating hormone
(FSH) release from anterior pituitary.
• Stimulate luteinizing hormone (LH) release
from anterior pituitary.
NEUROHORMONES
• Hormone~ Growth hormone-releasing
hormone.
• Symbol (s)~GHRH
• Stimulate Growth hormone (GH) release
from anterior pituitary.
NEUROHORMONES
• Hormone~ Somatostatin
• Other names~ growth hormone-
inhibiting hormone
• Symbols (s)~ SS/GHIH
• Inhibit the Growth hormone (GH) release
from anterior pituitary
• Inhibit thyroid-stimulating hormone (TSH)
release from anterior pituitary.
NEUROHORMONES
• Hormone~ Dopamine
• Other names~ Prolactin-inhibiting
hormone
• Symbols (s)~ DA/PIH
• Inhibit prolactin release from anterior
pituitary.
• Responsible for sexual arousal
NEUROHORMONES
• Hormone~ Oxytocin
• For uterine contraction.
• Lactation (letdown reflex or milk ejection
reflex)
NEUROHORMONES
• Hormone~ Vasopressin
• Other names ~ antidiuretics hormone
• Symbols (s)~ ADH/AVP
• Increased water permeability in the distal
convoluted tubule and collecting duct of
nephrons, thus promoting water reabsorption
and increasing blood volume
hypothalamus-121023052119-phpapp01.pdf

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hypothalamus-121023052119-phpapp01.pdf

  • 3. WHAT IS HYPOTHALAMUS? • The portion of the brain that contains a number of small nuclei with a variety of functions. • The control center of all autonomic regulatory activities of the body.
  • 4.
  • 5.
  • 6. LOCATION AND STRUCTURE • It is located in the middle of the base of the brain, and encapsulates the ventral portion of the third ventricle. • A small cone-shaped structure, it projects downward, ending in the pituitary stalk, a tubular connection to the pituitary gland.
  • 7.
  • 8. FUNCTION • The most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland. • It synthesizes and secretes certain neurohormones, often called hypothalamic-releasing hormones, and these in turn stimulate or inhibit the secretion of pituitary hormones.
  • 9.
  • 11. NEUROHORMONES • Thyrotrophin- releasing hormone (TRH) • Corticotrophin-releasing hormone (CRH) • Gonadotropin-releasing hormone (GnRH) • Growth hormone-releasing hormone (GHRH) • Growth hormone-inhibiting hormone • Prolactin-inhibiting hormone • Oxytocin • Vasopressin
  • 12.
  • 13. NEUROHORMONES • Hormone ~ Thyrotrophin-releasing hormone • Other names ~ Prolactin-releasing hormone • Symbol(s)~ TRH/TRF/ or PRH • stimulate thyroid-stimulating hormone (TSH) release from anterior pituitary hormone (primarily). • Stimulate prolactin (PRL) release from anterior pituitary.
  • 14. NEUROHORMONES • Hormone~ Corticotrophin-releasing hormone • Symbols (s) ~ CRH/CRF • Stimulate adrenocorticotrophic hormones (ACTH) release from anterior pituitary.
  • 15. NEUROHORMONES • Hormone~ Gonadotropin-releasing hormone • Symbols (s) ~ GnRH/ LHRH • Stimulating follicle-stimulating hormone (FSH) release from anterior pituitary. • Stimulate luteinizing hormone (LH) release from anterior pituitary.
  • 16. NEUROHORMONES • Hormone~ Growth hormone-releasing hormone. • Symbol (s)~GHRH • Stimulate Growth hormone (GH) release from anterior pituitary.
  • 17. NEUROHORMONES • Hormone~ Somatostatin • Other names~ growth hormone- inhibiting hormone • Symbols (s)~ SS/GHIH • Inhibit the Growth hormone (GH) release from anterior pituitary • Inhibit thyroid-stimulating hormone (TSH) release from anterior pituitary.
  • 18. NEUROHORMONES • Hormone~ Dopamine • Other names~ Prolactin-inhibiting hormone • Symbols (s)~ DA/PIH • Inhibit prolactin release from anterior pituitary. • Responsible for sexual arousal
  • 19. NEUROHORMONES • Hormone~ Oxytocin • For uterine contraction. • Lactation (letdown reflex or milk ejection reflex)
  • 20. NEUROHORMONES • Hormone~ Vasopressin • Other names ~ antidiuretics hormone • Symbols (s)~ ADH/AVP • Increased water permeability in the distal convoluted tubule and collecting duct of nephrons, thus promoting water reabsorption and increasing blood volume