How are \"gamete,\" \"chromosomes,\" and \"zygote\" related? Gametes combine to form a zygote with one set of chromosomes. Gametes unite, forming zygotes with two sets of chromosomes. A gamete undergoes mitosis, doubling its chromosome number and becoming a zygote. A gamete undergoes meiosis, forming a zygote with one set of chromosomes. Meiosis undergo is divided into Somatic Germ gives rise to cells cells Gametes are are nclude Meiosis I Meiosis II Diploid Haploid cells cells results in Sperm cells Genetic contain contain egg variation two sets of one set cells homologous of combine to form diploid Chromosomes zygote Solution Gametes unite, forming zygotes with two sets of chromosomes. The zygote, the first cell of a new organism with an individual genome is created by the alignment of the maternal chromosomes together with the paternal ones on a common spindle apparatus..