Apathy Definition

Apathy Definition
Before infrastructure, before wildlife, before the oceans, and before the sun, was the one specimen that created all that came prior: the human brain.
The brain, in all its intricacy and wonder, can cause the greatest pain and the greatest success. The very framework the brain embodies succumbs to its
purpose of formulating ideas or creating makeshift plans to haphazardly carry out. Humans, the most complex of all creatures in the world, exemplify
the notion of using their brains for creativity, critical thinking, and extreme to moderate emotional ranges. However, with this intellectual power, comes
great opposition, as man's greatest obstacle has become overcoming his emotional severity to utilize his mind's sole purpose: rational thinking.... Show
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Although apathy is accredited to the intricacy of the human brain and how it absorbs immediate content, apathy is strictly unaffordable. The limitations
the brain asserts on humanity is unaffordable. Due to the instability of the environment's future, the rising sea level must be made a very steady danger.
People must be made highly aware of the threats, implications, possibilities, and immediacies, through any mechanism they encounter with, may it be
through news stations or media outlets. The strength of unity among humans must be depended upon to eradicate apathy. Science has spoken, the
environment has lectured, and the ocean will soon shout. Time is not on the planet's side, and apathy quickens the pace of absolute destruction. Climate
change is not a hopeless cause, as long as the looming culmination of the rising sea level is not hidden away by the thunderous and covert operations
through ennui and lack of involvement by the human race. Neutral plasticity is a real component of the brain's gift that keeps on giving, and humans
can initiate change in their own minds and create their own neural networks. Connections can be made and destroyed, and responses can be
manipulated in response to new situations and changes in the environment. The preceding solutions to apathy only prove how flexible and
revolutionary the human brain can be in times of
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Episodic Memory
Klein et al. (2002) suggested that the function of episodic memory is providing information storages of counter–examples of semantic summaries, to
achieve adaptive decision rules that guide organism's behaviors. At the same time, from reflection on my own episodic memory which does not
correspond with this function, I assume that other function of episodic memory is to construct simulations for the future. As Schacter et al. (2007)
mentioned, one of the key psychological elements of episodic memory is "scene building", which is performed by a whole brain neural network
including prefrontal regions, the MTL, and the hippocampal region. In other words, the storage of episodic information enables us to construct
simulations of alternative perspectives

Global Effort against Malaria
Facilitated largely by increased political commitment, an up–scaling of World Health Organisation (WHO) vector control measures and expansion of
the so–called "artemisinin–based combination therapies", the past decade has seen remarkable progress in the global effort against malaria. In fact,
latest figures approximate that global investments in malaria control have amassed to a 42% reduction in the diseases' mortality rate between 2000 and
2012, saving an estimated 3.3 million lives during this period.1 Additionally, malaria incidence rates declined by 25% worldwide, in the same epoch,
and by 31% in the African region – the epicentre of disease's devastation on humanity.1
Despite the recent advancements, however, there remains no opportunity for complacency. Malaria continues to represent a perilous public health
challenge and one of the most prevalent and lethal infectious agents across Africa, Asia and the Americas. Data released in December 2013 indicates
that there were in the range of 207 million cases of malaria in 2012, and an estimated 627,000 related deaths – most particularly in children under five
and expectant mothers.2 In Africa today, it can be predicted that a child will die every forty–five seconds as a result of malaria.3 To quote WHO
Director–General Dr Margaret Chan, "the fact that so many people are dying from mosquito bites is one of the greatest tragedies of the 21st
century".1 In 2008, the Roll Back Malaria (RBM) Partnership unveiled its Global

The Next Graph Is Displayed In Figure 3 And Appears To
The next graph is displayed in Figure 3 and appears to be a double bar graph with the title "Afghanistan Population Pyramid." From this picture, the
author is attempting to identify the percentage of males versus females for specific age groups in Afghanistan. By using this graph the author appears
to understand how to use visuals, but is not quite perfect yet. The concept is there, but the x–axis is a percentage versus an actual number which is not
appropriate for a bar graph. Although the blue does not look unappealing, it could technically be wrong for this graph. Locker and Kienzler (2014),
blue can mean strong, trustworthy, authoritative, cold, depressing, or gloomy. A better color scheme for this graph would be pink for females and
...
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Therefore, the message is unclear because we have a wonderfully colored map where the meaning is not understood. The other thing that attributes
to the confusion is the word subregion. This map is a view of the world separated by each country whereas a region would be better defined as a
continent such as Europe or the general geographical area such as the Middle East. The colors make sense, but they could be improved. It can be
assumed that the higher percentage in a specific area will be bad therefore a color that resembles a bad thing such as red might be better than orange.
The strategy of using lighter colors for lower percentages is clever except for the dark blue in the 0.5–0.9% group. White was a great choice for the
lowest grouping because of its meaning of empty or pure (Locker and Kienzler, 2014. According to Stengel, Calori, and Giannoudis (2008), this graph
is almost graphically excellent because it lacks chart junk, but the smaller clusters are difficult to see in some cases and the data could be
misleading. Once again we see the example of leaving data out from Misleading Graphs: Real Life Example's (2014) since some geographical space
is larger than others to include the number of people that live there. For example, the reader should expect Russia to have a higher percentage versus
Cuba because of the

Exon Junction Complex
Social activities are the most fundamental behaviors for many animal species to survive and require memory formation. Particularly, patients with
autistic spectrum disorders (ASD) exhibit several core symptoms, including impaired social activities and repetitive behaviors, often combed with
intellectual disability (ID). Memory formation entails new protein synthesis from mRNAs stored at the synapses responding to local stimuli. Neuronal
transcripts interact with various mRNA–binding proteins (RBPs) and the RBPs ensure the targeted mRNAs to be translated only when receiving
proper environmental signals. Significant accomplishments have identified over 1000 RNA binding proteins (RBPs) crucial for accurate
post–transcriptional RNA processing.... Show more content on Helpwriting.net ...
Our group is in the ideal position to address these problems. We are the first group to demonstrate that the EJC factor, RBM8a, regulates anxiety–like
behaviors and neuronal plasticity1. We have developed the RBM8a conditional knockout (cKO) mice and our preliminary data demonstrated that
region specific knockout of RBM8a impairs social interaction and affect fear memory. Additionally, RNAseq uncovered that RBM8a modulates a
large set of genes overlapping with autism risk genes, which are involved in neurotransmission and synaptic plasticity. However, current knowledge
gaps include how RBM8a regulates memory and synapse development, which physiological neuronal substrates are directly regulated by RBM8a in
vivo during learning behaviors, and what happens to these transcripts when the RBM8a level is altered. Our hypothesis is that RBM8a regulates
activity dependent neuronal plasticity and controls specific pools of transcripts in neurons that are activated by social interaction and learning
activities. Building on a novel discovery of an essential role of RBM8a in social recognition, our goal in this proposal is to identify targets that are
most relevant for RBM8a–dependent neuronal defects and determine the effect on RNA substrates of RBM8a in the brain. To achieve this goal, the
following aims will be

Seed-Based Analysis : Functional Comution Maps Using The...
The functional connectivity maps using the fcPAT data from Nasiriavanaki and colleague's research was extracted using the seed
–based analysis, where
the Pearson correlation was used as the similarity metric cite{nasiriavanaki2014high}. After each seed's temporal trace was found, Pearson's
correlation can be performed between the seed's temporal trace and the temporal trace of each pixel in the image. This results in a correlation map that
shows functionally corresponding regions of the brain, both intra– and interhemispherically. The correlation maps for the mouse brain that were
acquired with fcPAT can be shown in Figure 5 for a number of different seed locations.
includegraphics[scale=0.5]{fig2}
textit{Figure 5.} Functional ... Show more content on Helpwriting.net ...

subsection{Parcellation}
The purpose of the parcellation algorithm was to divide the surface of the brain into functional regions in a data–driven manner that does not require
any input from the user cite{white2011imaging}. The avoidance of user intervention avoids any bias that accompanies the choice of seed location,
and it removes the requirement for global signal regression cite{damoiseaux2009greater}. The parcellation algorithm, described in detail below,
automatically groups pixels with similar temporal traces into the same functional region and encodes the different regions with different colors.
includegraphics[scale=0.45]{parcellationprocedure}
textit{Figure 6.} Demonstration of the parcellation procedure for the primary somatosensory brain region cite{nasiriavanaki2014high}.
Figure 6 demonstrates the parcellation procedure for a single functional region. The position of each functional region from the Paxinos atlas was used
as a starting point to define a probable functional region in the acquired fcPAT images. The probable region was a disk that was centered at the
corresponding center of the atlas, with a diameter equal to the longest length of that region in the atlas, to assure that the whole potential functional
region is within the probable

Descriptive Essay About Mexico
Mexico is an astonishing place full of adventures awaiting to be found by people that are willing to visit. It's a very large country that consists of vast
subregions that offer different climate, vegetation, and overall feel depending where you are. Mexico is very prepossessing, the cities and culture are
what makes this country so astounding to visit as I did. I last visited Mexico on a cruise in the summer of 2015, and the cruise made its voyage toward
the destination of Mexico. The first stop was Progreso, and it's a marvelous city on the northern tip of the Yucatan peninsula of Mexico. It offers a
rich history and great views for people to enjoy. Docking in the long white concrete port, I saw miles and miles of the dark blue ocean, it looked
just like the clear blue sky, waves gently struck the vessel. The town boasts a population of about 50,000 people, which makes this city not a largely
populated city, but a favorable size that makes it impeccable for travelers of all kinds. This is a great spot for people to relish in without having to
encounter the busy city life like the ones back home. Progreso's battered streets offer character that other places can't provide. Winding through these
narrow streets are many people trying to make a living of their own. As the streets go farther and farther, they eventually lead up into a tropical
environment that is like it's out of a movie scene. There's hefty, green, and lush tropical trees that give a very soothing feeling

The Modern American South
x. The Modern American South
GEOGRAPHY: USA
From Chapter 6 – THE SOUTH
http://www.geog.nau.edu/courses/alew/gsp220/text/chapters/ch6.html
© Alan A. Lew, 2004, all rights reserved
Southern Distinctiveness
The Lowland South is one of the more distinctive regions in the US. Language accents are stronger and more diverse here than in any other part of the
country. Politics and religion are more conservative and fundamental than elsewhere. Historically, settlement occurred later than in the North and at
much lower densities. African slaves were brought in to relieve the problems of under–population. Today, theCaribbean has become a major focus of
the region's international trade and immigration.
Southern States map
~
Commonalties
The ... Show more content on Helpwriting.net ...
A high pressure system sits much of the year over the Atlantic Ocean between Florida and northAfrica. Known as the 'Bermuda High' (and bringing
great weather to Bermuda most of time), this high pressure system circulates in a clockwise direction, moving warm air from the equator into the South.
In the winter, this flow is occasionally broken by thrusts of cold arctic air from the middle of the continent. (The cooler winter temperatures is what
distinguishes the Humid Subtropical climate from the year–round Humid Tropical climate.) The Gulf Coast, including Florida, receives the most
precipitation (averaging 50 inches of rainfall a year) and the warmest temperatures. The inland portions of the South receive precipitation levels of 40
inches a year, while further north the Midwest region averages 30 inches a year. Changing Images
Non–Southerners have traditionally held rather negative images of the Lowland South as a place of racial conflict, intolerable climate, and

underdevelopment, yet, in recent years, the South has grown as a major part of the Sunbelt. It is a distinct region which is undergoing considerable
dynamic change in the postindustrial US.
The American South Homepage*
The Vernacular

World Population Data Sheet At A Glance
Activity 1: The World Population Data Sheet at a Glance
A. Find answers to the following questions using the current World Population Data Sheet. Use your blank world maps to locate, shade, and label the
countries identified in the questions that follow.
What is the current population of the world?
The current population is 7.3 billion. 2. Rank, in descending order, the 10 countries with the largest population.
China, India, United States, Indonesia, Brazil, Pakistan, Nigeria, Bangladesh, Russia, Mexico.
B. Rates are often used, instead of absolute numbers, to determine how frequently a population or demographic event is occurring–rates show how
common an event is. Rates also make it possible to compare countries that vary greatly in ... Show more content on Helpwriting.net ...
Which African country has the highest proportion of people living in urban areas? In Asia? In Latin America? In Europe? In Oceania?
Reunion in Africa, Bahrain, Qatar, and Singapore in Asia, Puerto Rico in Latin America, Monaco in Europe, and Nauru in Oceana.
F. Gross national income in purchasing power parity per capita (GNI PPP/capita) converts income into "international dollars" and indicates the amount
of goods and services one could buy in the United States with a given amount of money.
Which country is the wealthiest in terms of GNI PPP/capita? Which is the second wealthiest? Which are the poorest two countries?
The wealthiest is Qatar, the second wealthiest is Kuwait, and the two poorest countries are Central African Republic and Congo, Dominican Republic.
G. A population grows because there are more births than deaths or more people are moving in than moving out. The difference between births and
deaths is expressed as a percentage called the rate of natural increase.
Which major region is growing the fastest through natural increase? Which Major region is growing at the slowest rate? Within the major regions
identified, which subregions are growing fastest? ...

Integrated Computer Aided Engineering And Information...
Integrated Computer–Aided Engineering 0 (2017) 1?0 1 IOS Press A Region Division Based Diversity Maintaining Approach for Many–Objective
Optimization Linqiang Pan a,c, Cheng He a, Ye Tian b, Yansen Su b, and Xingyi Zhang b,? aKey Laboratory of Image Information Processing and
Intelligent Control of Education Ministry of China, School of Automation, Huazhong University of Science and Technology, No. 1037, Luoyu Road,
Wuhan, 430074, China E–mail: {chenghehust, lqpanhust}@gmail.com b Institute of Bio–inspired Intelligence and Mining Knowledge, School of
Computer Science and Technology, Anhui University, No. 111, Jiulong Road, Hefei, 230039, China E
–mail: {?eld910921, xyzhanghust}@gmail.com,
suyansen1985@163.com c School of Electric and... Show more content on Helpwriting.net ...
Experimental results on these problems demonstrate that the competitiveness of the proposed algorithm in solving many–objective optimization
problems, especially for those with irregular Pareto optimal fronts. Keywords: Many–objective optimization, region division, diversity maintaining,
irregular Pareto front 1. Introduction Most real–world optimization problems are charac– terized by the existence of multiple, often con?ict– ing,
objectives [10,29], such as electrical engineer– ing [44], engineering modelling [6,43,49,53], indus– trial scheduling problems [28,58] and robotics and
control [5,40,48]. These optimization problems are *Corresponding author. E–mail: xyzhanghust@gmail.com. called multi–objective optimization
problems (MOPs) and they can be described as follows Minimize F (x) =(f1(x), f2(x), . . . , fM (x)) (1) subject to x ? X, where X is the search space of
decision variables with objective number M larger than two [12,9]. Many–objective optimization problems (MaOPs) refer to MOPs involving more
than three objectives [30], which are very common in real–world applications, 1875–8835/17/$17.00 c? 2017 ? IOS Press and the authors. All rights
reserved 2 L. Pan et al. / A region division based diversity maintaining approach for many–objective optimization see e.g. [20,22,37]. For MOPs, there
does not typ– ically exist a single solution that minimizes all ob– jectives simultaneously. Hence, attention is paid to Pareto optimal solutions, that

The Nexus Between Women 's Land Rights And Food Security...
Introduction
This research is interested in identifying the nexus between women' land rights and food security within West African states (ECOWAS states). The
majority of ECOWAS countries sustain their economies through agriculture. In 2012, agriculture accounted for 35% of the region's Gross Domestic
Product (DGP), contributing $6 billion to its foreign trade and represented 16.1% of products and services exported from ECOWAS region (Salifou
2012). Agriculture also created 60% all jobs in the ECOWAS region in 2012.
Women accounted for 60–80% of the production, processing and marketing of agricultural produce in the region. About 80% of the regional
population's food needs are met by regional produce, with the remaining 20% being met by import (Salifou 2012). Several imperial studies reveal
that African women, compared with other regions, are "far more involved in agriculture" (Adekaney, Otitulaiye and Opaluwa 2009). One study in
Nigeria showed that men abandoned areas like food crop farming because those sectors are considered as unprofitable (Afolabi 2008). Other studies
also revealed that 80% of all staple food consumed in Ondo State of Nigeria in 2005, and 80% of all the staple food produced in Ghana were locally
produced and processed by women (Bravo, Seufferhand and Agunbiade 2011).
While women play a substantial role in the production, marketing and distribution of agricultural produce, their access to land, an important means of
production, is hindered by

The Pacific Northwest Region Is A Good First Step
While we have been focusing on the whole Pacific Northwest region as a whole this class, we have finally delved into a subregion that is close to all
of us: the Inland Empire. This area in the Pacific Northwest came into being during the late 19th Century and encompassed much of Eastern
Washington, the Idaho Panhandle and parts of Eastern Oregon. The people of this region were very proud of their land and some even held more pride
for the Inland Empire than their own state. This fierce loyalty to one's home was just as much a product of economic growth as many of the other
changes being see all around the Pacific Northwest in general. The Inland Empire was, and is, an important subregion that was born of economic
development and competition with the cities on the coast.
To set the stage for the Inland Empire, a broader look at the changes occurring throughout the Pacific Northwest region is a good first step. Around the
late 19th century, the region was experiencing economic boom. Industrialization of many of the region's commodities like salmon processing flooded
the region with money and immigrants. These peoples came from the Far East to work in the factories and lumber mills that were making Seattle and
other cities such as Portland and Tacoma booming hubs of trade. Foreigners took note of the changes as well, Rudyard Kipling was just a young man
when he visited the region but he wrote about the progress in his journals. "More Chinamen with yellow, crooked fingers,

A Description Of Bayesian Rational Selection Methods
2.5 Full Bayesian set up j пїјпїјUsing residual information from the pde as prior for basis selection a Bayesian variable selection method can be
devised. Posterior estimates are computed at each time point sequentially from the estimate of the earlier tie points. At each time point one/or more
subregions are selected П‰ The following gives the joint prior based on pde model and the prior on the coefficient, by some ad hoc cut off on
О±п°‡ j . At each selected subregion the extra basis are selected from the following posterior distribution. For a schematic representation see Figure 4,
right panel. Prior and Posterior ПЂ1(О , (I, J , T )) в€
ј ПЂ(un+1(x, t)|ОІn+1(In+1, J n+1), un) H (8) for a model dependent constant c ((I,J)n+1). On
ОІn+1 flat normal... Show more content on Helpwriting.net ...
Let R(k),E(k) and R(в€’k),E(в€’k) be the corresponding linear form and the residual and I в€’ Ik be t set of other indices. For the regularization
problem: minОІ+ 2ПѓL2 + 2Пѓ12 , let R, E the value of the residual and пїјпїјп°‚11п°ѓ11 KTK + STS ОІп°€ = KTb + STg. For the index 2П
ѓ12 +
2ПѓL2 2Пѓ12 пїјпїјпїјпїј2ПѓL2 set I let the minimizer be ОІ(I)+. The posterior sampling can be performed by a Gibbs sampling algorithm after
marginalizing over the coefficient of the additional basis ОІ+. MCMC Algorithm P(Ik=1|Iв€’Ik)= p with 1в€’p p = О±п°‡k exp 1 в€’ p 1 в€’ О±п°‡ k
п°‚Л†2Л†2Л†2Л†2п°ѓ в€’в€
ҐR(k)в€
Ґ в€’ в€
ҐR(в€’k)в€
Ґ в€’ в€
ҐE(k)в€
Ґ в€’ в€
ҐE(в€’k)в€
Ґ (10) 2 Пѓ L2 2 Пѓ 12 пїјпїјпїјпїјпїјwhere О±п°‡k is the
prior probability of selecting that additional basis. Here, Nmc is the number of MCMC sample and the posterior distribution given the index set If d is
a linear function, then d(un) becomes a linear function of ОІ+n and therefore its posterior distribution becomes multivariate normal given I. For the
MCMC step ОІ+n is marginalized and the MCMC step only depends on the least square error and the prior for the selected index set. For nonlinear
case, this posterior normality of the coefficient given the index set does not hold and that results in a prohibitive acceptance rejection based
Metropolis–Hastings algorithm as each step requires solving big linear system. To address this problem a Laplace approximation (Tierney and Kadane,
1986; Raudenbush et al.

Johnson Montgomery Foreign Aid Essay
Sending massive amounts of foreign aid to other countries impacts countless lives. Many people, like Johnson C. Montgomery, believe that foreign
aid is a waste of money. Foreign aid is defined as "economic, technical, or military aid given by one nation to another for purposes of relief and
rehabilitation, for economic stabilization, or for mutual defense". Montgomery wrote an article, which was published in Newsweek in 1974, stating
his opinion on this issue. He was a California attorney and a member of the Zero Population Growth and attended Harvard University and the Stanford
University Law School. His main claim in his article is that the US shouldn't share wealth with other poorer nations. Montgomery is incorrect because
of three reasons, such as poverty, environmental problems, and medical assistance.
Poverty is one of the biggest problems the developing countries deal with today and foreign aid helps ease that pain. Poverty is more than one issue; its
lack of shelter, hunger, and jobs. Southeast Asia, India, andAfrica are some of the poorest subregions and continents that need the US's help. In Africa
there are over 40% people living in absolute poverty. ... Show more content on Helpwriting.net ...
For example, use the money to control the massive debt US has. According to Crystal Lombardo, a chief editor of a foreign aid website, the budget
for foreign aid is only 1% of US dollars. Another reason would be that it will lead a nation to always depend on another nation when they are
trouble. However, this builds a relationship between these nations which can lead to diplomatic relations and military services. These are all good
points but how can the US be so selfish if they can help another country survive. Developing countries are suffering from dirty water and infectious
diseases and some people want to look the other way. Foreign aid not only helps others but the US as well with opening up potential trade agreements
and create a better

Synaptic Plasticity And Memory Essay
We sincerely thank the reviewers for recognizing the innovation and novelty in our proposal and the significance of the proposed research in
understanding the role of lncRNAs in synaptic plasticity and memory consolidation. We are excited that only minor weaknesses were pointed out by
Reviewers 2 and 3 and that there were no major criticisms by all three reviewers on this revised R21 application. Because we know very little about
lncRNAs and their function in synaptic plasticity and memory consolidation, our studies will bring novel insights into the role of lncRNAs in the
mammalian brain. Importantly, our systematic dissection of the function of lncRNAs in sub–regions of the hippocampus will have a major impact in
our understanding of synaptic plasticity and memory storage as well as on mechanisms of drug addiction. We are particularly thankful to the comments
from Reviewer 1.." The study is motivated by the idea that some lncRNAs might be transcribed in the hippocampus to promote formation of fear
memories, and thus that pharmacological manipulation of learning–induced levels of these lncRNAs might provide a novel approach to preventing
consolidation of traumatic memories such as those associated with PTSD. The project idea is innovative... Show more content on Helpwriting.net ...
There is no mentioning alternative and more sensitive test (Reviewer 2). The reviewer commented that we might miss mild effects of lncRNAs in
plasticity and memory storage. Mild effects of lncRNA expression changes will be difficult to dissect in vivo. Given that lncRNAs are critical
mediators of transcription and translation, the two key processes that regulate long–term synaptic plasticity, we are confident that we will be able to
identify lncRNAs that are critical for synaptic plasticity and memory. We are certainly interested in the mild effects of lncRNAs, but during the
two–year funding of this project, we sought to identify and characterize lncRNAs that are necessary for synaptic plasticity and memory

Holothurian Overfishing
One of the famous instances is overfishing of holothurians that occurred in the 1980s. Holothurian is a precious marine creature which is also known
as sea cucumber or bГЄche–de–mer. It began with Macassan fishers, who fished holothurian before twentieth century, leaving centuries–old tradition of
trepang fishing in the Great Barrier Reef areas, where black teatfish is the main targeted species. Because of the increasing need for sea cucumber in
East and Southeast Asia, where holothurian is regarded as a delicacy, abundant amount of black teatfish are harvested from the Great Barrier Reef and
the Coral Sea each year, "with a harvesting peak of 2.3 million pounds in 1989" (Benzie and Uthicke 59). One outstanding characteristic of holothurian
... Show more content on Helpwriting.net ...
Dugong, which is commonly called sea cow, is claimed to be the only marine herbivorous mammal on Earth. These days, most of the world's
population of dugongs are in the waters around Queensland, resulting in "one of the reasons for nominating the Great Barrier Reef as a World
Heritage Area in 1981" (Lawler, Marsh, McDonald, and Stokes 2). On The IUCN Red List of Threatened Species published in 2015, dugong was
classified to be vulnerable because "the numbers of dugongs around the world had declined by at least 20% over the last 90 years" (Marsh and
Sobtzick), which was approximately three dugong generations. The dugongs fishing in Australia started in 1850s, when people hunted dugongs for
their meat and oil and then exported to Europe for medical purposes. Over the years, people kept searching for dugongs to attain ample amount of
profits from dugong trading, so unsustainable hunting became a leading reason which was responsible for dugong's decline in sea area around
Queensland. As the report from World Conservation Union indicates, "the [Great Coral Reef] region supported an estimated 4,220 dugongs in the
mid–1990s compared with 72,000 dugongs in the early 1960s" (Marsh and Sobtzick). Even though international law had banned the trade in dugong
meat and other related products, dugong hunting remained legal in some Australian regions, since "aboriginal people regard dugongs as vital parts of
their

Anatomical Connections Between Hypothalamic OT Neurons And...
Overview: The proposed work is designed to unravel detailed anatomical connections between hypothalamic OT neurons and distal brain neurons
(Aim1 and 2) and their function in the CLA–EPd complex in order to begin understanding how this signaling system regulates social behavior (Aim3).
We plan to combine our novelbrain mapping tools with genetic and viral tools to examine neural connection of OT neurons, along with behavioral
assays to begin learning how the OT signaling system controls social behavior.
Specific Aim1. Determine topographical output projection from OT–expressing neurons of the hypothalamus.
Scientific Premise and Rationale: OT producing neurons in the hypothalamus project to different brain regions where they release OT to ... Show more
content on Helpwriting.net ...
Feasibility and Preliminary Results
3D distribution of OT neurons in the hypothalamus: We used knock–in mice expressing Cre recombinase under OT promoter (OT–Cre, developed by
Gloria Choi's lab at MIT)[29] crossed with Cre dependent reporter mice (CAG–LoxP–Stop–LoxP–tdTomato, called "Ai14")[31]. Four–week old mice
were perfused and imaged by serial two–photon tomography (Figure 2). We performed the imaging registration of the 3D reconstructed brain to the
common reference brain in order to display the precise 3D location of OT neurons (Figure 2A)[25]. and observed the strong expression in PVH, SO,
accessory nuclei (AN) and tuberal nucleus (TU) of hypothalamus (Figure 2), consistent with previous finding [11]. Immunohistochemistry using a
specific OT antibody further confirmed that the tdTomato signal from the Cre recombinase–positive neurons is overlapped well with OT immuno
positive neurons (Figure 2C). Figure 2. 3D pattern of hypothalamic OT neurons. (A) Top view of the tdTomato signal from OT–Cre:Ai14 to highlight 4
major hypothalamic nuclei (arrows) after image registration to the reference brain. The 3D view is from the purple box area of the reference brain in
the insert. (B) Zoom–in 3D view of OT neurons in PVH from the top (B1), front (B2), and side (B3) view. Images are from the dotted boxed area in
(A). Note, the side view (B3) is marked by three different PVH divisions along anterior–posterior axis. (C) tdTomato (+) neurons from

Park Ridge Is A Population Of 37856 People Essay
Park Ridge has a population of 37,856 people; it consists of a median resident age of 44 years ("Park Ridge, Illinois"). Estimated median household
income is $85,967 and an estimated median house or condo value is $364,345 ("Park Ridge, Illinois"). The demographics of the people living in
Park Ridge consists of 87 percent Whites, 6.7 percent Hispanics, 3.7 percent Asians, and 1.1 percent Blacks ("Park Ridge, Illinois"). As I traveled
around the neighborhood of the Maine East High School, I observed a numerous resources in terms of restaurants areas, groceries stores, and overall
real estate development of the area. There are several opportunities in the area; lots of up and coming companies and businesses are present.
Furthermore, groceries store like Jewel–Osco was 2 blocks away from the actual school itself; and the area has a ton of other alternatives options for
shopping. Malls and big plazas surrounds the area and offer lots of useful stores can be found almost anywhere (See appendix 1).
Large homes surround Maine East High School (See appendix 4). District 207 revenue by source for the year 2014–15 indicates that local property
taxes for the district are $113,093,113, other local funding are $6,215,628, general state aid are $3,217,216, and other state funding are $4,239,735,
coming to a grand total of $130,270,117 for the District of 207 which only has three schools: Maine East, Maine West, And Maine South ("Illinois
School Report Card"). These numbers are incredible

Abortion
Chapter 5 South America Multiple Choice Introduction 1.Which of the following countries does not contain a significant portion of the Andes? *A.
ParaguayB. ArgentinaC. Peru D. ColombiaE. Venezuela 2.Which of the following countries does not contain a portion of the Amazon Basin? A.
BrazilB. EcuadorC. Peru D. Colombia*E. Chile 3.The religion most closely associated with South America is: A. Islam*B. Roman CatholicismC.
Incanism D. CokismE. Coptic Christianity 4.In South America, the richest 20% of the population control _____ of the wealth. A. 2%*B. 67%C. 90%
D. 1%E. 95% The Human Sequence 5.An altiplano is: A. a low area with small mountains *B. a plain high in the Andes C.... Show more content on
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the Amazon River predominates D. oil is a major natural resource E. most of the area is a D climate 27.In the Mestizo–Transitional Region: *A. the
population is of mixed Amerindian/European origin B. most of the area has a plantation economy C. the Amazon River predominates D. oil is a major
natural resource E. most of the area is a D climate Economic Integration 28.Which of the following is not a current attempt at economic integration in
South America? A. Mercosur*B. LAFTAC. Andean Group D. Group of 3E. FTAA Urbanization 29.Overall, South America's population has a high
growth rate, but nowhere does the population grow faster than: A. in the rural areas*B. in the cities and townsC. in the Amazon Basin D. in the Andean
altiplanosE. in Uruguay 30.South America's large cities: *A. with few exceptions fit Jefferson's concept of the primate city B. are usually not the
capitals C. are often found in the interior, such as Buenos Aires D. are experiencing a net out–migration E. have very low unemployment rates
31.About ____ percent of South Americans live in urban areas. A. 50B. 20*C. 75 D. 10E. 90 32.Which of the following statements is false? A. South
America is more urbanized than Middle America. *B. Although South America's population is growing at an alarming rate and will be larger than that
of the United States early in the 21st century, it

Oceania Research Paper
Oceania is a region composed by Australia, the smallest continent, and islands close to it, which are, Fiji, Kiribati, Marshall Islands, Federate States of
Micronesia, Nauru, New Zealand, Palau, Papua New Guinea, Samoa, Solomon Islands, Tonga, Tuvalu, Vanuatu, Cook Islands and Niue. This region is
located on the center of the Pacific Ocean, it is divided in subregions, which are Melanesia, Micronesia and Polynesia. Oceania's main climates are
tropical, which is a non–arid climate and through entire year has a mean of at least 64 degrees, and change from humid to seasonally dry. The most
humid parts of the islands presents tropical and subtropical forest and in the driest parts, tropical dry forest predominates. Due to an historical isolation,
Australia has a big number of animals and plants, atolls that are sparsely vegetated. Many people believe that Polynesians were the first people to
reach America by sailing in small canoes, this theory is called, the Polynesia theory. Oceania was colonized by a different type of colonization
called "wastes of colonization", this region began to be explore in the 16th century by the Europeans. Ferdinand Magellan and James Cook are the
most famous Europeans to reach Oceania. Micronesia started to be settled about 4,000 years ago and they had a decentralized chieftain system, in
Melanesia, the first people arrived about 40,000 years ago, they moved from Southeast Asia, Indigenous Australians, which refers to Aboriginal and
Torres Strait Islanders, were the first settlers of Australia and arrived there about 70,000 years ago, coming from Africa and Asia. Australia was
colonized by the British, and, at first, the Australian territory was used as a prison. New Zealand was and still is occupied by the Maori, Abel Tasman
was the first European to reach this island in

Hippocampal Shape Analysis
Many studies focus on the statistical analysis of volume measurements of the hippocampus as for example for the study of Alzheimer's disease [6]. But
such studies do not capture the shape complexity of the structures observed in MRI. Analyzing shapes of structures can provide a better understanding
of the anatomical variability of the brain, which is a very challenging problem since healthy brains have a high variability, and it is important to
understand the mechanisms, the morphological changes and the impacts of diseases.
Predicting or classifying dementia based on hippocampal shape analysis is an active field of research. In [7], Statistical Shape Models (SSMs) have
been used to model the variability in the hippocampal shapes among the population. In [8], they characterize shape abnormalities of subcortical and
ventricular structures as well as the subregions of the hippocampus and the amygdala in subjects with MCI or AD within framework of Large
Deformation Diffeomorphic Metric (LDDMM). In [9] they propose a template–based analysis of anatomical variability in populations, also in the
framework of LDMM. ... Show more content on Helpwriting.net ...
This method solves the correspondence problem by the alignment of the spherical parametrization using a first order ellipsoid [10]. In [11], they
propose a method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly
controls, based on multidimensional classification of hippocampal shape features. This approach uses spherical harmonics (SPHARM) coefficients to
model the shape of the hippocampi. However, as this method establishes correspondence on simplified spherical models of surfaces, it is restricted to
surfaces with spherical topology and is computationally

Example Of Exercises And Games
Exercises and Games
Get your group of onlookers associated with diversions and exercises that assistance them gather data and become more acquainted with each other. On
the off chance that they sit too long, their brains begin to work more in a uninvolved mode than in dynamic mode. You can make your introductions
intuitive by utilizing PowerPoint toolboxs like the Game Show PowerPoint Template.
Exact Statistics
You can astound your group of onlookers by taking care of measurements and numbers deliberately. It can demonstrate your point as well as will add a
remark introduction. Additionally, point by point guidelines ought to be given on a freebee and diagrams and charts must be sufficiently basic for the
gathering of people to get ... Show more content on Helpwriting.net ...
Therefore, this compelling method will absolutely enable you to make your introduction an impeccable one.
Characteristics OF AN EFFECTIVE PRESENTATION
Qualities OF A GOOD PRESENTATION
Toward THE BEGINNING
Introduce the theme
State what is known
State what stays obscure
Introduce the principle question

Indicate how this function fits into the master plan
Convince the gathering of people of the significance of the work
Toward THE END
Refer to the first fundamental inquiry and how this examination has tended to the inquiry
State the essentialness of this work and how it identifies with the "10,000 foot view"
Consider unanswered inquiries
Suggest new inquiries that have emerged from this work
Suggest conceivable future examinations
DO's
Organize along this organization: Intro, Methods, Results (and their suggestions), Discussion
Establish eye to eye connection with group of onlookers
Provide a review
Become comfortable with all strategies and procedures
Explain why a specific procedure was utilized
Use your own words and illustrations
Make beyond any doubt you comprehend the most troublesome perspectives
Anticipate addresses and have answers prepared.
Practice the whole talk while timing yourself

Record your discussion and tune in for blunders or harsh spots
Carefully point to subregions inside the figures
Screen

Human Drug Screening For Memory
As compounds are optimized by our ROP criteria, we will progress lead compounds towards in vivo efficacy studies, which will be in three
well–established and well–accepted mouse models for memory storage. These three tests capture various forms of memory (working memory, object
recognition memory and fear memory) in mice and have translational validity for human drug screening for memory disorders. Based on the published
data from our lab and others (Ref) our working hypothesis is that positive compounds will enhance memory storage. The following preliminary results
support the feasibility of this aim.
C5A.1. Regulation of specific kinesins in mouse hippocampus during contextual fear memory storage: We have studied whether levels of specific
kinesins change during memory formation. We selected 6 kinesin genes from the hippocampus (HPC) and carried out qRT–PCR analysis of RNAs
from HPC (N=4 biological replications) isolated one hour after contextual fear conditioning (CFC) training, during the initial consolidation of the
long–term memory. We identified KIf5B to be significantly upregulated (~1.7 fold, N=4; Students t test, p<0.005) in the HPC following CFC training
(Fig ).
C5A.2. Stereotaxic surgeries and delivery of compounds to specific regions of mouse brain. These studies are ongoing in the Puthanveettil lab (Figure
XX). An example of such study is shown in Figure XX, where we injected a lentiviral vector to express eGFP in CA1 sub–region of the mouse
hippocampus.

How Did Shifting Cultivation Impact Social, Environmental,...
Shifting cultivation is defined as "a productive system of agriculture in which small plots are cleared in forestlands, the dried brush is burned to
release nutrients, and the clearings are planted with multiple species; each plot is used for only 2 or 3 years and then abandoned for many years of
regrowth" (Pulsipher 2000 "Glossary") Indigenous settlers in forested uplands, river floodplains/deltas, coastlines, and mountainous mainland which
make up 60% of the population in SE Asia, have thrived using shifting cultivation as well as hunting/gathering and other agricultural techniques for the
past 1000 years. (Pulsipher 2000 "Southeast Asia") Shifting cultivation has impacted Southeast Asia in two ways; by providing sustaining crops and
profit for indigenous rural peoples, government action in eliminating shifting cultivation mainly in terms of opium poppy crops. One way shifting
cultivation impacts SE Asia is that it provides traditional and the "bare–minimum" of subsistence crops and profit for the 176 indigenously ethic groups
making up 14.7% of the population in Cambodia, Laos, Myanmar, Thailand, Vietnam, and Yunnan. Of all the total forest area, the rural locals use only
5% of it for shifting cultivation. This low percentage is partly caused by a priority in the mountainous mainland of Southeast Asia, or MMSEA. The
priority is the national as well as global protection of the watershed system and the biophysical environment. Therefore, the rurals rely on the

Polarization In America Essay
Lately, America has become divided by a single issue; one which appears to be so polarized, that no one can compromise on it. Just kidding, there
are a lot of those kinds of issues americans can't agree upon. We are separated by race, language and ideas. Continuously homogenized and then
filtered apart again into different groups and identities. So many conflicting interests clashing against each other in a never ending battle. Yet despite
all that, America is held up as a pillar of democracy, freedom, liberty, opportunity; in America, you can be anything you want if you work at it. This
is what we are lead to believe, if you work hard enough eventually you will be rewarded and make money. This may or may not be true but it's beside
the point.... Show more content on Helpwriting.net ...
Quindlen suggests an answer for the second questions, that the American psyche revels in the doing the impossible and the demanding and so savor
the impossibility of this conglomerate that is America. Another part of us identifies with them, as the current immigrants are similar to our own
forefathers. In her poem, Emma Lazarus eloquently states this. "Give me your tired, your poor, Send these, the homeless, tempest–tost to me, I lift my
lamp beside the golden door!" (Lazarus) She uses one of America's biggest symbol of hope and freedom, Lady Liberty, as a beacon to draw attention
to the fact that America is made up of immigrants. Ethnicity and race are not the only things that divides us however. Dividing us further still is
geography, religion, politics and lifestyle. We must focus on our idea of whatever we think America is or should be, even though they may differ
from somebody else's idea. It is the only way that we can hope to survive attacks and

Africa South Of The Sahara Research Paper
Measurement Topic 2: Africa South of the Sahara
Learning Target 2: Geography of Africa South of the Sahara
Step 2: Cultural geography of Africa South of the Sahara
Read the attached document on the cultural features of Africa South of the Sahara to answer the following questions:
How has the physical environment of the Sahel influenced ways of life in this subregion?
The Sahel, the land of Africa beneath the Sahara, is filled with large water systems and a range of elevated lands: plateaus, mountains, and valleys. In
some ways, it made for an easier life. Having the large water regions near by allowed for advanced irrigation systems and immediate access to water
for drinking, health care, and taking care of livestock. The landforms; however,

Regional Development and Regional Blocks
Regional Development and regional blocks
1. Development of Regional blocks, goals and institutions
ASEAN
The Association of Southeast Asian Nations (ASEAN) was established on 8 August 1967 in Bangkok, Thailand
ASEAN Declaration Founding Fathers of ASEAN (5 countries)
Today – 10 Member States
NAFTA
The North American market increased, create a free trade, elimination of tariff barriers
North American free Trade Agreement (NAFTA)was formed on 1 January 1994 Richest market in the world– Canada, United States, Mexico
MERCOSUR
Countries common values of economic development, the fight against poverty, sustainable development and so on An economic and political
agreement (Southern Common Market) was formed on 26 March ... Show more content on Helpwriting.net ...
Approval of applications shall require the unanimous decision of the States Parties"
3. Cooperation with other countries
ASEAN and Australia
ASEAN 's first Dialogue Partner in 1974 Longstanding and deep relationship Joint Declaration on the ASEAN–Australia Comprehensive Partnership
AANZFTA (2009)– ASEAN, Australia, New Zeland Two
–way trade with ASEAN – 14.5 % of Australia 's total trade. (2011)
Exports
Crude petroleum Gold Wheat Copper

Imports
Refined petroleum Crude petroleum Good vehicles Gold
ASEAN–Australia summit (2010) – discussed new funding and support for ASEAN by Australia:
– В«Australia is investing A$132 million in infrastructure connectivity related initiatives in the Greater Mekong Subregion, in cooperation with the
World Bank and the Asian Development Bank– Australia will contribute A$10 million over four years to the Tripartite Action to Protect Migrants
within and from the Greater Mekong Subregion from Labour Exploitation (TRIANGLE) initiative in cooperation with the International Labour
Organisation – Supported by Australian funding, the Australian Human Rights Commission will build linkages with the ASEAN Intergovernmental
Human Rights Commission.В»
Australia is a leading provider of

Physical Objects Without Temporal Parts Analysis
Simplicity and Explanation: Physical Objects without Temporal Parts Philosophers debate over how to resolve the Problem of Change. The Problem of
Change identifies a challenge for philosophers accounting for object persistence. To account for how an object persists, the Problem of Change bring
up disagreements over the existence of temporal parts. In this paper, I present and explain a view wherein an object persists through change without
positing the existence of temporal parts. As an adequate and simpler theory, it remains the perdurantists to raise further objections. Until such time, the
endurantist account of change continues to provide the best explanation of object's persistence through time. Views debating the existence of temporal...
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This position involves specifying the properties an object has at a particular time. The parts of x at t uniquely share all of the spatial properties of x at
t. Endurantists need not give up Leibniz's Law. Endurantists whom maintain y's properties are discernable from x's need not reject Leibniz's Law. In
fact, many hold Leibniz's Law applies to enduring objects. Moreover, the law may help endurantists explain change. A non–temporal parts theorist
distinguishes between x at t and y at t'. Endurantist typically employ said law to argue that a single object persists at time t and also at t'. The object at
time t has the property being–at–t, and that very object can change so that at t' it no longer has being–at–t. Objections to endurantists' explanation of
change similarly challenge the perdurantists' notion of objects having parts which are temporal slices of the object. According to Lowe, spatial parts
bare a relation to each other. He argues changes across spatial parts change their relation to one another (Lowe). The relationships, which are not
themselves parts of the object, can be pointed at to pick out an object at one

Hippocampal Subregions
Accumulating evidence has shown that age–related episodic memory differences are closely associated with the development of hippocampal
subregions. In particular, area CA1 is believed to play a significant role in the encoding of related experience. Prior work has pointed out that memory
integration occurs during the encoding of two related events. Previous studies have also suggested that the developmental changes in CA1 volume are
related to the improvement in associative inference from childhood to adulthood. However, it remains an open question whether contextual information
of two related episodes will influence memory integration and the ability to make associative inference. Also, little is known about whether this impact
changes ... Show more content on Helpwriting.net ...
It has been shown that the development of the ability to combine events that share common information is supported by the improvement of episodic
memory behaviors (Martin–Ordas et al., 2014). Further, age–related memory differences can be attributed to the development of hippocampal
subregions (DeMaster et al., 2016). In particular, Cornu ammonis fields 1(CA1) functionally contribute to the encoding and generalization of related
events (Schlichting et al., 2014). The improvement in associative memory inference from childhood to adulthood is also related to the developmental
changes in CA1 volume (Schlichting et al., 2016).
While a host of studies (Schohamy & Wagner 2008; Schlichting & Preston 2014; Schlichting& Preston 2015) have highlighted that experiencing
overlapping content can lead to memory integration and thus facilitates memory inference, it remains unclear whether increased similarity of two
related episodes will influence memory. One open question is how overlapping contexts across multiple episodes will affect memory integration and
inference. Additionally, whether this impact changes over development is also not well characterized. In this study, by manipulating the contexts in
which related events occur as blank, identical or different, I will be investigating the impact of overlapping contextual information on memory
integration and inference in both children and adults. I will employ a modified version

A Report On Hotel Investment Conference Africa
PRESS RELEASE
AFRICA IS STILL THE 'GO TO' PLACE FOR HOTEL INVESTORS–
UNPACKING THE OUTCOMES OF HOTEL INVESTEMENT CONFERENCE AFRICA 2014
South Africa, Pretoria, 29 September 2014: "Africa remains the 'go to' place in the world, in as far as hotel investment and growth is concerned – and
it will be for some time to come" says one of South Africa's leading economists and Chief Economist for Investment Solutions, Chris Hart.
Addressing delegates at the recent Hotel Investment Conference Africa (HICA), which was held in Johannesburg, South Africa, from 14th to 16th
September, Hart touched on the contentious issue of South Africa's new immigration regulations and said it was critical for Governments to remove
obstacles which serve as ... Show more content on Helpwriting.net ...
Another session, titled the World and Sub Saharan Africa in 2014, provided a detailed review of the SSA region's hotel performance in comparison to
other parts of the world.
Notable highlights from the two sessions
West Africa leads the hotel development pipeline with about 87 hotels planned. A total of 51% of these hotels are in preplanning, whilst 49% are in
construction. 40 of the hotels planned in this region will be in Nigeria; East Africa comes a close second with 33 hotels planned and Tanzania leading
hotel development pipeline and in Southern Africa, South Africa has a total of 9 hotels in the pipeline;.
African cities which have been performing well in terms of occupancies and increasing average daily rates (AVR) include Accra, Abuja. Addis Ababa,
Cape Town and Windhoek;
Resources and ICT sectors are fuelling hospitality investment drive in the Continent;
From a funding and capital sourcing perspective, a more knowledgeable, more experienced hotel owner class was beginning to emerge, which will
have a greater influence on the future growth and sustainability of the sector
Africa must tell its own story
Despite the UNWTO's projections that international arrivals into Africa would reach 134 billion by 2020, the conference acknowledged that Africa still
had the

The 1787 Philadelphia Constitutional Convention
The 1787 Philadelphia Constitutional Convention involved an extensive amount of compromise among the delegates in order to finalize the U.S.
Constitution into the structure that it is known for today. On one end of the spectrum were states' righters, or Antifederalists, who were often delegates
from smaller states such as Connecticut, and who sought to scale back the power of the federal government. On the other end of the spectrum were the
Federalists, who wanted a strong national government to unite the nation. Additionally, there were other delegates who could not be put into such
clear–cut categories. What followed at the convention was the process of compromise: a group of men with different ideas about how government
should be structured,... Show more content on Helpwriting.net ...
It made several proposals regarding the structure and powers of the federal government. Under the Virginia Plan, both houses in the legislature would
have their representatives decided according to a state's number of free citizens. It was assumed by Madison that both large and small states would
agree to this proposal; however, the smallest states were opposed because they knew they would have less Congressional power under this
governmental structure. Roche uses words like "militant" and "truly radical" when describing the structure of the federal government under the
Virginia Plan. Both he and Lance Banning relate the support Madison's plan received to the delegates' memories of the behavior of state legislatures
under the Articles of Confederation. It is not surprising, therefore, that some delegates first supported a plan that would protect against abuses of
power by the states. In response to the Virginia Plan, states' righters began supporting the New Jersey Plan, which called for equal representation in
every state. Roche describes it as a "reversion to the status quo under the Articles of Confederation with but minor

Bordeaux Wine Region
BORDEAUX 89% of wine produced in Bordeaux is red (called "claret" in Britain), with sweet white wines (most notably Sauternes), dry whites,
rosГ© and sparkling wines (CrГ©mant de Bordeaux) collectively making up the remainder. Terminologies Claret– is a name primarily used in British
English for red Bordeaux wine. Claret derives from the French clairet, a now uncommon dark rosГ©, which was the most common wine exported from
Bordeaux until the 18th Sauternes – is a French sweet wine from the Sauternais region of the Graves section in Bordeaux. ChГўteaux – is a manor
house or residence of the lord of the manor or a country house of nobility or gentry, with or without fortifications, originally–and still most frequently–in
It is an excellent complementary grape variety that rarely makes up the majority of the final blend. It adds freshness, finesse, and aromatic
complexity as well as hints of raspberry and violet. White Grapes SAUVIGNON BLANC Sauvignon Blanc, except in rare instances, is the most
important variety for dry white wines. It provides the wines with the necessary acidity as well as minerality, aromatic freshness, and varietal aromas,
such as citrus, boxwood, and fig leaves. White Grapes SEMILLON SГ©millon is the main grape variety for semi–sweet and sweet white wines and is
almost always a component of dry white wines as well. It contributes roundness, richness, and apricot and honey aromas. When affected by В«noble
rotВ», it develops an inimitable bouquet. White Grapes MUSCADELLE Muscadelle, which plays a secondary role in the blend for both dry and
sweet white wines (generally no more than 10%), is a fragile but very interesting variety with musky floral overtones. Viticulture Bordeaux is a
relatively humid region. Thus it is a place rife with diseases and other problems that afflict vines, compared with many of the world's other wine
regions, such as dry Chile or Australia. In Bordeaux, the pruning of the vine happens almost always as cane–pruning (as opposed to spur–pruning).
There are two types of cane–pruning: guyot simple and guyot double. The use of chemicals and fertilizers has

Essay On Multiscale Basis
2.2 Modeling the solution using multiscale basis
Selecting the dominant scale corresponding to the small eigen values gives rise to a fixed basis sets and using fixed basis to solve the weak form
produces the fixed solution un,fixed(x,t) = п°„ n n,П‰j n H n,П‰j i,j ОІi,j П†i (x,t), where ОІi,j's are defined in each computational time interval and
П†i (x,t) are fixed basis functions. Fixed solution at n + 1 th time point is computed by solving equation
(3) by setting un as the fixed solution at n th time point and writing un+1 in the space of HH
5
пїј1 0.9
0.8П‰E K 0.7
0.6
0.5
0.4
0.3
KK 1П‰2 i 0.2 KK
0.1
0
0 0.2 0.4 0.6 0.8 1
Figure 3: Illustration of fine grid, coarse grid, coarse neighborhood and oversampled domain. fixed basis at n + 1 th time ... Show more content on
Helpwriting.net ...
The true solution is assumed to be normal around the fixed solution with small variance. Finally, this structure enables us to compute the posterior or
conditional distribution of the basis selection probability and conditional solution of the system given the observation and the pde model.
Residual and selection probability on the subregion and basis
From equation (3), the residual is defined as
Rn(un+1,un+1 ,un
) =
п°†
О© fn+1v в€’ п°†
п°† un+1+un+1в€’un

+ fixed fixed v v + fixed fixed
О© n+1
в€†t
+ ufixed) В· в€‡v.
(4)
+ Оєв€‡(u+ n+1
О©
6
For any fixed basis П†n,П‰j 's this equation is zero as the fixed solution is constructed by setting the k n,П‰j equation zero for each fixed basis.
Using П†k,+ 's в€
Ђk, j in the residual function one can compute the residual for additional basis and writing down the residual as a long vector over
subregions and basis the following quantity is defined. Let О±П‰k = в€
ҐRnП‰k в€
Ґ/в€
ҐRnв€
Ґ,where Rn is the global residual vector and RnП‰k
is the local residual vector in П‰k (as mentioned earlier) and L1 norm is used .
Let NП‰ be the average number of subregions where additional basis will added. Furthermore, О±П‰j О±п°‡ j = п°„j О±П‰j NП‰, (5) П‰ With
probability proportional to О±п°‡ j в€§ 1, the region П‰j , is selected and Jj = 1 if the region is П‰ п
їјselected and zero otherwise. Given subregion j
is selected the k th extra basis is

Consolidation: The Case Of Declarative Memory Avoidation
Memory consolidation is a process of gradual stabilization that new memories must undergo in order to persist (MГјller and Pilzecker, 1900). In the
case of declarative memories (or explicit learning), consolidation initially takes place within the hippocampus before these memories become
permanently stored within the neocortex. Evidence for this time– and region–dependent systems consolidation has been demonstrated by lesion and
imaging studies in primates and rodents indicating that recent memories are stored within the hippocampus, whereas remote memories are stored in the
neocortex (McClelland et al., 1995; Squire and Alvarez, 1995; Frankland and Bontempi, 2005). Several lines of evidence from rodent studies suggest
that the medial prefrontal

Hippocampal Traces In Early Childhood
Discussion The goal of the present study was to examine the relation between autobiographical memory and hippocampal subregion volumes in early
childhood. First, results from the autobiographical narratives revealed that all dimensions used to measure coherence increases with age. Thus,
suggesting that autobiographical memory improves between the ages of 4– to 8– years. Previous research has shown that important developmental
changes occur during early childhood, which leads to improvements in autobiographical memory (e.g., Hamond & Fivush, 1991; Habermas, Negele, &
Mayer, 2010; Piolino et al., 2007). These results are consistent with these findings and further illustrate autobiographical memory improves during early
childhood.
Secondly, novel findings from our study showed that the volume of hippocampal subregions in 4– to 8– year old children is positively correlated with
autobiographical memory. Specifically, results revealed a positive correlation between chronology during free recall and the volume of the right
hippocampal tail. Similarly, a positive correlation was observed between chronology in prompted recall and the volume of the right hippocampal tail.
Collectively, these findings ... Show more content on Helpwriting.net ...
The coding scheme was developed to assess the coherence of narratives across lifespan, from preschool through adulthood. Additionally, the context
dimension should be modified when examining the relation between autobiographical memory and hippocampal subregion volumes. It should account
for the difference in posterior and anterior hippocampal activation when local spatial detail of an autobiographical event is recalled versus when
general location is recalled. This adaptation will allow future studies to observe if there is a correlation between context and the volume of hippocampal

Early Onset Of The Disorder
Bipolar, or manic–depression, is a mood disorder that is typically diagnosed during mid teenage years to early adulthood. Many people believe that
mid teen years are the earliest a diagnosis can be made, however the disorder can be diagnosed in early childhood. Early onset of the disorder is
often much more severe, and is harder to treat. The possible causes for early onset are similar to those of late onset. Symptoms are also similar,
however those in early onset can be more serious. Diagnosis of the disorder at an early age is often difficult and seen as unlikely. Treatments are
often stigmatized, though they are similar to those prescribed for late onset of the disorder. The exact cause of bipolar disorder is currently
unknown, however there are several factors that could increase the likeliness of developing the disorder. Structures or deformations of many
important parts of the brain can lead to the disorder. Structures like the basal ganglia and the cerebellum tend to be smaller in individuals with the
disorders (Comer, 2004). According to Comer malformation of structures such as the amygdala, hippocampus, or the prefrontal cortex could also
cause the disorder (2004). These structures are responsible for fear response, regulation of emotion, and decision making (Comer, 2004). One of the
possible causes of the disorder are neurotransmitters, overactive norepinephrine can result in a manic episode, while low levels can result in a
depressive episode (Free, 2016). Many

Healthcare Care Access Disparities in Appalachia
Health Care Access and Disparities within the Appalachian Region
Sherri Drake
PIMA Medical Institute
Health Care Access and Disparities within the Appalachian Region (NIH, 2002–2006) Health disparities are defined as "differences in the incidence,
prevalence, mortality, and burden of diseases and other adverse health conditions that exist among specific population groups in the United States".
Health care access is the ability of a person to receive health care services as a function of access to medical personnel, supplies and the ability to pay
for those services. The Appalachian region consists of thirteen states and 420 counties, in which the entire state of West Virginia is inAppalachia, along
with the mountainous portions of ... Show more content on Helpwriting.net ...
The 18% poverty level of 2008 is improved from the 33% level of the 1960's, this decrease is attributable to an increase in educational attainment and
income, resulting in lower levels of poverty. Borak, Salipante–Zaidel, Slade & Fields (2012) state the following
Education is also strongly linked with health status; limited education is regarded as a "precursor to poor health"...In general, the counties with lowest
educational attainment were "concentrated in central Appalachia, especially in the mining regions," where health status is generally worst.
Even with some improvements in the region, Appalachia continues to linger below the U.S. average. (Halverson & Bischak, 2008) Suggests that
two socioeconomic factors stand out when evaluating health disparity among mortality rates and those are poverty levels and the percentage of
persons who do not have health insurance coverage. Behavioral risk factors in the region have a higher prevalence of obesity, smoking, lack of
exercise and poor use of cancer screenings available than the U.S. national average. Again, the central subregion of Appalachia is among the most
affected as this area tends to be more geographically rural. Nutrition is a major issue and low income levels often dictate poor food choices. Some
areas may have only one small grocer with limited selections available. Exercise becomes more difficult for people who become obese, which often
leads

The Effect Of New Protein Synthesis At Prl Cortex
training. Mice infused with anisomycin (n= 12) immediately after conditioning showed impairment in contextual fear memory compared with
vehicle–infused animals (saline, n=18) when tested 24 hours after CFC training (DF=28, F=7.19, t–test: p< 0.05) (Figure 2A). Surprisingly, irrespective
of the overall decrease in freezing percentage, mice injected with anisomycin did not show any statistical difference in the level of freezing within the
first 2 minutes of the test (Figure 2B). By the third minute of testing, ANI–injected mice show a significant decrease in their level of freezing, showing
statistical significant differences until the end of the test (drug Г— memory minutes of test DF=28, F=13.16, t–test p< 0.01; DF=28, F=7.66, t–test p<
0.01; DF=28, F=5.46, t–test p< 0.05) (Figure 2B). These results suggested that new protein synthesis at PrL cortex is critical for the encoding of
contextual fear memories.
To further understand new protein synthesis at PFC, we asked whether other subregions of PFC are also critical for encoding of contextual fear
memories. To address this question, we studied the role of cingulate cortex 1 (CG1) region of PFC in encoding. We injected anisomycin to inhibit
protein synthesis at CG1. Four separate groups of animals received anisomycin and saline infusions into the adjacent CG1 (Saline, n= 8; ANI, n=6;
Figure 2 C and D). As in the case of Prl cortex, anisomicyn was injected shortly after CFC training. Measurements of freezing at 24 hours

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