Surface Acoustic Wave Sensor for Protein Detection
1. Surface Acoustic Wave Sensor for Protein Detection 1Peter D. Southland, 1Ilya I. Lifshits, 1Andrew B. St. Amour, 2Dennis J. O’Rourke, 2Daniel A. DiJohnson, 3David L. Arruda, 2Brian C-S. Liu, and 1Douglas E. Dow 1Dept. of Electronics and Mechanical, Wentworth Institute of Technology, Boston, MA, USA 2Molecular Urology Laboratory, Division of Urology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA 3Medical Engineering & Medical Physics, Harvard-MIT Health Sciences & Technology, Boston, MA, USA
4. SAW sensorsArruda DL, Wilson WC, Nguyen C, Yao QW, Caiazzo RJ, Talpasanu I, Dow DE, Liu BCS; “Microelectrical Sensors as Emerging Platforms for Protein Biomarker Detection in Point-of-care Diagnostics”, Expert Review of Molecular Diagnostics, 9(7):749-755, 2009.
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6. As gel solidified and dried, the SAW output signal progressively became more attenuated and delayed (increased phase shift)
17. To develop toward a point of care platform, the instrumentation for the SAW sensor signal generation and analysis should be miniaturized .
Editor's Notes
SAW are small waves that propagate just below a surface and may be generated on piezoelectric solids when excited by an electrical voltage sine wave at the resonant frequencyNotes for speaker: SAW are small waves that propagate just below a surface and may be generated on piezoelectric solids when excited by an electrical voltage sine wave at the resonant frequency