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Spinal Cord Injury (SCI) - Any injury to the spinal cord that is caused by trauma instead of disease.
Depending on where the spinal cord and nerve roots are damaged, the symptoms can vary widely, from
pain to paralysis to incontinence. Spinal cord injuries are described at various levels of "incomplete",
which can vary from having no effect on the patient to a "complete" injury which means a total loss of
function.

Your spinal cord is protected by the vertebral column (also known as the spinal column or backbone).

The human spinal column is made up of 33 bones - 7 vertebrae in the cervical region, 12 in the thoracic
region, 5 in the lumbar region, 5 in the sacral region and 4 in the coccygeal region.

The outer layer of the human spinal cord consists of white matter, i.e., myelin-sheathed
nerve fibers.

These are bundled into specialized tracts that conduct impulses triggered by pressure, pain, heat, and
other sensory stimuli or conduct motor impulses activating muscles and glands. The inner layer, or gray
matter, is mainly composed of nerve cell bodies. Within the gray matter, running the length of the cord
and extending into the brain, lies the central canal through which the cerebrospinal fluid circulates.

A spinal cord injury (SCI) can occur anywhere along the spinal cord. It is the result of damage to cells in
the spinal cord and causes a loss of communication between the brain and the parts of the body below the
injury.

Effects of a SCI may include low blood pressure, inability to regulate blood pressure effectively, reduced
control of body temperature, inability to sweat below the level of
injury, and chronic pain.

Complete and Incomplete Spinal cord                                      Picture of the human spinal cord
injuries (SCI)
Complete Spinal Cord Injury: Generally persons with a complete spinal cord injury suffer a loss of
sensation and motor ability caused by bruising, loss of blood to the spinal cord, or pressure on the spinal
cord; cut and severed spinal cords are rare. Generally, complete spinal cord injuries result in total loss of
sensation and movement below the site of the injury.

Incomplete Spinal Cord Injury: An incomplete spinal cord injury does not result in complete loss of
movement and sensation below the injury site. These injuries are usually classified as:

Anterior cord syndrome: Damage to the front of the spinal cord, affecting pain, temperature and
touch sensation, but leaving some pressure and joint sensation. Often motor function is unaffected.

Central Cord Syndrome: Form of incomplete spinal cord injury in which some of the signals from the
brain to the body are not received, characterized by impairment in the arms and hands and, to a lesser
extent, in the legs. Sensory loss below the site of the spinal injury and loss of bladder control may also
occur. This syndrome, usually the result of trauma, is associated with damage to the large nerve fibers that
carry information directly from the cerebral cortex to the spinal cord. These nerves are particularly
important for hand and arm function. Symptoms may include paralysis and/or loss of fine control of
movements in the arms and hands, with relatively less impairment of leg movements. The brain's ability
to send and receive signals to and from parts of the body below the site of trauma is affected but not
entirely blocked.
Brown-Sequard syndrome: Injury to the lateral half of the spinal cord. The condition is characterized
by the following clinical features found below the level of the lesion - contralateral hemisensory anesthesia
to pain and temperature, ipsilateral loss of propioception, and ipsilateral motor paralysis. Tactile
sensation is generally spared.

Spinal contusions: The most common type of spinal cord injury. The spinal cord is bruised but not
severed. Inflammation and bleeding occurs near the injury as a result of the injury.

Injuries to individual nerve cells: Loss of sensory and motor functions in the area of the body to
which the injured nerve root
corresponds.

Cervical (neck)
injuries (C1 - C8)

C1 or atlas

The Atlas is the topmost vertebra,
and along with C2, forms the joint
connecting the skull and spine. Its
chief peculiarity is that it has no
body, and this is due to the fact that
the body of the atlas has fused with
that of the next vertebra.

C2 or axis

Forms the pivot upon which C1
rotates. The most distinctive
characteristic of this bone is the
strong odontoid process (dens)        The spine is surrounded by many muscles and ligaments to give it
which rises perpendicularly from      strength
the upper surface of the body. The
body is deeper in front than behind, and prolonged downward anteriorly so as to overlap the upper and
front part of the third vertebra.

Injuries to C-1 and C-2 can result in a loss of many involuntary functions including the ability to breathe,
necessitating breathing aids such as ventilators or diaphragmatic pacemakers.

C4 (cervical vertebra)

The fourth cervical (neck) vertebra from the top. Injuries above the C-4 level may require a ventilator for
the person to breathe properly.

C5

5th cervical vertabrae down from the base of the skull, found in the neck. C5 injuries often maintain
shoulder and biceps control, but have no control at the wrist or hand.

C6 (cervical vertebra)
The sixth cervical (neck) vertebra from the top. The next-to-last of the seven cervical vertebrae. An injury
to the spinal cord between C6 and C7 vertebrae is called a C6-7 injury. These injuries generally allow wrist
control, but no hand function.

C7 or vertebra prominens

The most distinctive characteristic of this vertebra is the existence of a long and prominent spinous
process, hence the name vertebra prominens. In some subjects, the seventh cervical vertebra is associated
with an abnormal pair of ribs, known as cervical ribs. These ribs are usually small, but may occasionally
compress blood vessels (such as the subclavian artery) or nerves in the brachial plexus, causing
unpleasant symptoms. C-7 and T-1 can straighten their arms but still may have dexterity problems with
the hand and fingers. Injuries at the thoracic level and below result in paraplegia, with the hands not
affected.

C8

Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves
except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra.
In other words C8 is a nerve root not a vertebrae.

Thoracic Vertebrae (T1- T12)
The thoracic vertebrae increase in size from T1 through T12 and
represent the 12 thoracic vertebrae. The thoracic vertebrae are
situated between the cervical (neck) vertebrae and the lumbar
vertebrae. These thoracic vertebrae provide attachment for the ribs
and make up part of the back of the thorax or chest.

Damage or SCI's above the T1 vertebra affects the arms and the
legs. Injuries below the T1 vertebra affect the legs and trunk below
the injury, but usually do not affect the arms and hands.

Paralysis of the legs is called paraplegia.
                                                                       Human vertebra picture
Paralysis of the arms AND legs is called quadriplegia.

T-1 to T-8

Most often control of the hands, but poor trunk control as the result of lack of abdominal muscle control.

T-9 to T-12

Allow good trunk control and abdominal muscle control. Lumbar and Sacral injuries yield decreasing
control of the hip flexors and legs. Individuals with SCI also experience other changes. For example, they
may experience dysfunction of the bowel and bladder.

Lumbar Vertebrae (L1- L5)
The lumbar vertebrae graduate in size from L1 through L5. These vertebrae bear much of the body's
weight and related biomechanical stress.
The lumbar vertebrae are the largest segments of the movable part of the vertebral column, and are
characterized by the absence of the foramen transversarium within the transverse process, and by the
absence of facets on the sides of the body.

Some individuals have four lumbar vertebrae, while others have six. Lumbar disorders that normally
affect L5 will affect L4 or L6 in these individuals.

L1

The first lumbar vertebra is at the level as the ninth rib. This level is also called the important transpyloric
plane, since the pylorus of the stomach is at this level.

L3 - L5

A lot of motion in the back is divided between these five motion segments with segments L3 - L4 and L4 -
L5 taking most of the stress. L3 - L4 and L4 - L5 segments are most likely to breakdown from wear and
tear causing such conditions as Osteoarthritis.

L4 - L5 and L5 - S1

The most likely to herniate (herniated disc, bulging disk, compressed disk, herniated intervertebral disk,
herniated nucleus pulposus, prolapsed disk, ruptured disk, slipped disk). The effects of this can cause pain
and numbness that can radiate through the leg and extend down to the feet (sciatica).

L5

The fifth lumbar vertebra is the most common site of spondylolysis and spondylolisthesis.

Sacral Spine (s1 - S5)
The Sacrum is located behind the pelvis. Five bones (abbreviated S1 through S5) fused into a triangular
shape, form the sacrum. The sacrum fits between the two hipbones connecting the spine to the pelvis
located just below the lumbar vertebrae.

It consists of four or five sacral vertebrae in a child, which become fused into a single bone after age 26.
The sacrum forms the back wall of the pelvic girdle and moves with it.

The first three vertebrae in the sacral have transverse processes which come together to form wide lateral
wings called alae. These alae articulate with the blades of the pelvis (ilium).

As part of the pelvic girdle, the sacrum forms the back wall of the pelvis and also forms joints at the hip
bone called the sacroiliac joints. The sacrum contains a series of four openings on each side through which
the sacral nerves and blood vessels run. The sacral canal runs down the center of the sacrum and
represents the end of the vertebral canal.

Back pain or leg pain (sciatica) can typically arise due to injury where the lumbar spine and sacral region
connect (at L5 - S1) because this section of the spine is subjected to a large amount of stress and twisting.

People with rheumatoid arthritis or osteoporosis are inclined to develop stress fractures and fatigue
fractures in the sacrum.

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Brain

  • 1.
  • 2.
  • 3.
  • 4.
  • 5. Spinal Cord Injury (SCI) - Any injury to the spinal cord that is caused by trauma instead of disease. Depending on where the spinal cord and nerve roots are damaged, the symptoms can vary widely, from pain to paralysis to incontinence. Spinal cord injuries are described at various levels of "incomplete", which can vary from having no effect on the patient to a "complete" injury which means a total loss of function. Your spinal cord is protected by the vertebral column (also known as the spinal column or backbone). The human spinal column is made up of 33 bones - 7 vertebrae in the cervical region, 12 in the thoracic region, 5 in the lumbar region, 5 in the sacral region and 4 in the coccygeal region. The outer layer of the human spinal cord consists of white matter, i.e., myelin-sheathed nerve fibers. These are bundled into specialized tracts that conduct impulses triggered by pressure, pain, heat, and other sensory stimuli or conduct motor impulses activating muscles and glands. The inner layer, or gray matter, is mainly composed of nerve cell bodies. Within the gray matter, running the length of the cord and extending into the brain, lies the central canal through which the cerebrospinal fluid circulates. A spinal cord injury (SCI) can occur anywhere along the spinal cord. It is the result of damage to cells in the spinal cord and causes a loss of communication between the brain and the parts of the body below the injury. Effects of a SCI may include low blood pressure, inability to regulate blood pressure effectively, reduced control of body temperature, inability to sweat below the level of injury, and chronic pain. Complete and Incomplete Spinal cord Picture of the human spinal cord injuries (SCI) Complete Spinal Cord Injury: Generally persons with a complete spinal cord injury suffer a loss of sensation and motor ability caused by bruising, loss of blood to the spinal cord, or pressure on the spinal cord; cut and severed spinal cords are rare. Generally, complete spinal cord injuries result in total loss of sensation and movement below the site of the injury. Incomplete Spinal Cord Injury: An incomplete spinal cord injury does not result in complete loss of movement and sensation below the injury site. These injuries are usually classified as: Anterior cord syndrome: Damage to the front of the spinal cord, affecting pain, temperature and touch sensation, but leaving some pressure and joint sensation. Often motor function is unaffected. Central Cord Syndrome: Form of incomplete spinal cord injury in which some of the signals from the brain to the body are not received, characterized by impairment in the arms and hands and, to a lesser extent, in the legs. Sensory loss below the site of the spinal injury and loss of bladder control may also occur. This syndrome, usually the result of trauma, is associated with damage to the large nerve fibers that carry information directly from the cerebral cortex to the spinal cord. These nerves are particularly important for hand and arm function. Symptoms may include paralysis and/or loss of fine control of movements in the arms and hands, with relatively less impairment of leg movements. The brain's ability to send and receive signals to and from parts of the body below the site of trauma is affected but not entirely blocked.
  • 6. Brown-Sequard syndrome: Injury to the lateral half of the spinal cord. The condition is characterized by the following clinical features found below the level of the lesion - contralateral hemisensory anesthesia to pain and temperature, ipsilateral loss of propioception, and ipsilateral motor paralysis. Tactile sensation is generally spared. Spinal contusions: The most common type of spinal cord injury. The spinal cord is bruised but not severed. Inflammation and bleeding occurs near the injury as a result of the injury. Injuries to individual nerve cells: Loss of sensory and motor functions in the area of the body to which the injured nerve root corresponds. Cervical (neck) injuries (C1 - C8) C1 or atlas The Atlas is the topmost vertebra, and along with C2, forms the joint connecting the skull and spine. Its chief peculiarity is that it has no body, and this is due to the fact that the body of the atlas has fused with that of the next vertebra. C2 or axis Forms the pivot upon which C1 rotates. The most distinctive characteristic of this bone is the strong odontoid process (dens) The spine is surrounded by many muscles and ligaments to give it which rises perpendicularly from strength the upper surface of the body. The body is deeper in front than behind, and prolonged downward anteriorly so as to overlap the upper and front part of the third vertebra. Injuries to C-1 and C-2 can result in a loss of many involuntary functions including the ability to breathe, necessitating breathing aids such as ventilators or diaphragmatic pacemakers. C4 (cervical vertebra) The fourth cervical (neck) vertebra from the top. Injuries above the C-4 level may require a ventilator for the person to breathe properly. C5 5th cervical vertabrae down from the base of the skull, found in the neck. C5 injuries often maintain shoulder and biceps control, but have no control at the wrist or hand. C6 (cervical vertebra)
  • 7. The sixth cervical (neck) vertebra from the top. The next-to-last of the seven cervical vertebrae. An injury to the spinal cord between C6 and C7 vertebrae is called a C6-7 injury. These injuries generally allow wrist control, but no hand function. C7 or vertebra prominens The most distinctive characteristic of this vertebra is the existence of a long and prominent spinous process, hence the name vertebra prominens. In some subjects, the seventh cervical vertebra is associated with an abnormal pair of ribs, known as cervical ribs. These ribs are usually small, but may occasionally compress blood vessels (such as the subclavian artery) or nerves in the brachial plexus, causing unpleasant symptoms. C-7 and T-1 can straighten their arms but still may have dexterity problems with the hand and fingers. Injuries at the thoracic level and below result in paraplegia, with the hands not affected. C8 Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra. In other words C8 is a nerve root not a vertebrae. Thoracic Vertebrae (T1- T12) The thoracic vertebrae increase in size from T1 through T12 and represent the 12 thoracic vertebrae. The thoracic vertebrae are situated between the cervical (neck) vertebrae and the lumbar vertebrae. These thoracic vertebrae provide attachment for the ribs and make up part of the back of the thorax or chest. Damage or SCI's above the T1 vertebra affects the arms and the legs. Injuries below the T1 vertebra affect the legs and trunk below the injury, but usually do not affect the arms and hands. Paralysis of the legs is called paraplegia. Human vertebra picture Paralysis of the arms AND legs is called quadriplegia. T-1 to T-8 Most often control of the hands, but poor trunk control as the result of lack of abdominal muscle control. T-9 to T-12 Allow good trunk control and abdominal muscle control. Lumbar and Sacral injuries yield decreasing control of the hip flexors and legs. Individuals with SCI also experience other changes. For example, they may experience dysfunction of the bowel and bladder. Lumbar Vertebrae (L1- L5) The lumbar vertebrae graduate in size from L1 through L5. These vertebrae bear much of the body's weight and related biomechanical stress.
  • 8. The lumbar vertebrae are the largest segments of the movable part of the vertebral column, and are characterized by the absence of the foramen transversarium within the transverse process, and by the absence of facets on the sides of the body. Some individuals have four lumbar vertebrae, while others have six. Lumbar disorders that normally affect L5 will affect L4 or L6 in these individuals. L1 The first lumbar vertebra is at the level as the ninth rib. This level is also called the important transpyloric plane, since the pylorus of the stomach is at this level. L3 - L5 A lot of motion in the back is divided between these five motion segments with segments L3 - L4 and L4 - L5 taking most of the stress. L3 - L4 and L4 - L5 segments are most likely to breakdown from wear and tear causing such conditions as Osteoarthritis. L4 - L5 and L5 - S1 The most likely to herniate (herniated disc, bulging disk, compressed disk, herniated intervertebral disk, herniated nucleus pulposus, prolapsed disk, ruptured disk, slipped disk). The effects of this can cause pain and numbness that can radiate through the leg and extend down to the feet (sciatica). L5 The fifth lumbar vertebra is the most common site of spondylolysis and spondylolisthesis. Sacral Spine (s1 - S5) The Sacrum is located behind the pelvis. Five bones (abbreviated S1 through S5) fused into a triangular shape, form the sacrum. The sacrum fits between the two hipbones connecting the spine to the pelvis located just below the lumbar vertebrae. It consists of four or five sacral vertebrae in a child, which become fused into a single bone after age 26. The sacrum forms the back wall of the pelvic girdle and moves with it. The first three vertebrae in the sacral have transverse processes which come together to form wide lateral wings called alae. These alae articulate with the blades of the pelvis (ilium). As part of the pelvic girdle, the sacrum forms the back wall of the pelvis and also forms joints at the hip bone called the sacroiliac joints. The sacrum contains a series of four openings on each side through which the sacral nerves and blood vessels run. The sacral canal runs down the center of the sacrum and represents the end of the vertebral canal. Back pain or leg pain (sciatica) can typically arise due to injury where the lumbar spine and sacral region connect (at L5 - S1) because this section of the spine is subjected to a large amount of stress and twisting. People with rheumatoid arthritis or osteoporosis are inclined to develop stress fractures and fatigue fractures in the sacrum.