organic synthesis map

1. © OCR 2017
Version 1
Haloalkane
Alcohol
1° 2°
Nitrile
Amine
Alkene
Aldehyde
Ketone
Carboxylic acid
Acyl chloride
1o Amide
2o Amide
Ester
Carboxylate
Alkane
Hydroxynitrile
halogen
UV
H2/Ni
hydrogen halide
H2O (steam)/H3PO4
NaOH(aq)
sodium halide /
H2SO4
CN–/ethanol
NH3/ethanol
H2/Ni
H3PO4 or H2SO4, heat
K2Cr2O7/H2SO4
distillation
K2Cr2O7/H2SO4
reflux
K2Cr2O7/H2SO4, reflux
NaBH4
alcohol/conc. H2SO4
NaBH4
NaCN(aq)/H+(aq)
SOCl2
H2O
dilute acid, heat
OH–
heat
alcohol
H2O/HCl, heat
primary amine
NH3
Synthetic routes (A Level) - reaction pathways
Aliphatic compounds
NaCN(aq)/
H+(aq)
H2/Ni
carboxylic acid/
conc. H2SO4 OR
acid anhydride
K2Cr2O7/H2SO4
reflux

2. © OCR 2017
Version 1
NH2
CH3
Br
Cl2/
Al Cl3 or Fe
or FeCl3
Br2/
Al Br3 or Fe
or FeBr3
conc. HNO3
conc. H2SO4
Sn/conc. HCl Br2
CH3COCl
Al Cl3
NaBH4
CH3Cl/
Al Cl3
Synthetic routes (A Level) - reaction pathways
Aromatic compounds

3. © OCR 2017
Version 1
Synthetic routes (A Level) - reaction pathways
Phenols
dilute HNO3
Br2
NaOH(aq)
and

4. © OCR 2017
Version 1
Haloalkane
Nitrile
Amine
Alkene
Aldehyde
Ketone
Carboxylic acid
Acyl chloride
Ester
Carboxylate
Alkane
Hydroxynitrile
Synthetic routes (A Level) - reaction pathways
Aliphatic compounds
Alcohol
1° 2°
1o Amide
2o Amide

5. © OCR 2017
Version 1
NH2
CH3
Br
Synthetic routes (A Level) - reaction pathways
Aromatic compounds

6. © OCR 2017
Version 1
OH
OH
NO2
OH
NO2
O
-
Na
+
and
Synthetic routes (A Level) - reaction pathways
Phenols