Acute inflammation is the early response of the body to short-term adverse stimuli and is not specific, involving dendritic cells, Kupffer cells, histiocytes, resistant macrophages, and mast cells in response to physical or chemical damage or pathogen invasion. Chronic inflammation is the prolonged inflammatory response lasting months or years, is specific involving acquired immunity, and responds to prolonged irritation by microorganisms through fibrosis and angiogenesis involving macrophages, neutrophils and lymphocytes.

1. Muhammad kamil khan
Microbiologist

2. 
 Acute Inflammation: Acute inflammation is the early
(short term) response of the body to adverse stimuli.
 Chronic Inflammation: The chronic inflammation is
an inflammatory reaction that lasts for months or
years.
Definition

3. 
 Acute Inflammation: The acute inflammation is not
specific.
 Chronic Inflammation: The chronic inflammation is
specific, it involves acquired immunity.
Specificity

4. 
 Acute inflammation: Acute inflammation is part of
the response of the body tissues to physical and
chemical damages, pathogen invasion, tissue
necrosis, etc.
 Chronic inflammation: Chronic inflammation is part
of the response of the body tissues to prolonged
irritation of chemicals; foreign particles – dust,
surgical thread, etc.; infection by microorganisms
that cannot be overcome for a long time by the body
– tuberculosis, syphilis, brucellosis.
Etiology

5. 
 Acute inflammation: The following immune cells are
involved in the acute inflammation process:
dendritic cells, Kupffer cells, histiocytes, resistant
macrophages, mast cells.
 Chronic inflammation: The following immune cells
are involved in the chronic inflammation process:
macrophages, neutrophils, lymphocytes.
Immune cells

6. 
 Acute inflammation: acute inflammation develops
the so called “triple response of Lewis: (1) redness,
(2) increased blood flow, and (3) edema.
 Chronic inflammation: The response in chronic
inflammation includes fibrosis and angiogenesis.
Response

7. 
 Acute inflammation: The cardinal signs of acute
inflammation are pain, heat, redness, and swelling.
 Chronic inflammation: The chronic inflammation
occurs without cardinal signs.
Cardinal signs

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