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Basic Neuro Anatomy
Chap1. Brain & Body
Ph.D. Jury Ham
Nerves system
1. CNS
Brain
Spinal cord
2. PNS
Somatic Nerve
Autonomic Nerve
201403 Ph.D. Jury HAM
A few definitions
201403 Ph.D. Jury HAM
A few Definitions
Locations in the Brain
 Described relative to neuraxis
- an imaginary line drawn through the spinal cord
up to the front of the brain
 The front end is anterior
 The back end is posterior
 The terms rostral (toward the head) and caudal (
toward the tail) are also used when referring to pa
rts of the brain
Dorsal (back) refers to the top of the head and
the back
The ventral (front) surface faces the ground.
These directions are somewhat more
complicated in humans because our neuraxis
bends, so that the top of the head is now
perpendicular to the back.
201403 Ph.D. Jury HAM
A few Definitions
Locations in the Brain
201403 Ph.D. Jury HAM
The Neuraxis
Anterior
Posterior
Dorsal
Ventral
201403 Ph.D. Jury HAM
The Neuraxis
Anterior
Posterial
DorsalVentral
superior
inferior
Lateral means to the side (away from the
neuraxis)
Medial (or mesial) means toward the middle
(towards the neuraxis)
Proximal: Areas of the brain that are near to
one another
Distal: Areas that are far from one another
201403 Ph.D. Jury HAM
A few Definitions
Locations in the Brain
201403 Ph.D. Jury HAM
A few Definitions
Locations in the Brain
 Ipsilateral refers to structures on the same
side of the body
 E.g. the olfactory bulbs send ipsilateral conne
ctions to the brain - the right bulb connects t
o the right hemisphere, and the left bulb con
nects to the left hemisphere
 Contralateral refers to structures on opposite
sides of the body
 E.g. the left motor strip connects to the right
side of the body
201403 Ph.D. Jury HAM
A few Definitions
Slices of the Brain
fornix
201403 Ph.D. Jury HAM
Division of nervous system
CNS
Central Nervous System
Brain
Spinal cord
PNS
Peripheral Nervous System
Cranial nerves
Spinal nerves
Copyright © The McGraw-Hill Companies, Inc. Permission required for
reproduction or display.
Brain
Spinal
cord Spinal
nerves
Cranial
nerves
201403 Ph.D. Jury HAM
Division of nervous system
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Sensory division Sensory
receptors
Motor division
Skeletal
muscle
Brain
Spinal
cord Spinal
nerves
Cranial
nerves
Central Nervous System
(brain and spinal cord)
Peripheral Nervous System
(cranial and spinal nerves)
Smooth m.
Cardiac m.
Glands
Autonomic
Nervous
System
Somatic
Nervous
System
201403 Ph.D. Jury HAM
Division of nervous system
Grey matter
White matter
CNS
PNS
Nuclei
Tracts
Ganglia
Nerve
201403 Ph.D. Jury HAM
Division of nervous system
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Receptor
Sensory or
afferent neuron
Motor or
efferent neuronCentral
Nervous
System
Effector
(muscle or
gland)
201403 Ph.D. Jury HAM
Classification of Neurons
Functional difference
Central nervous system Peripheral nervous system
Cell body
Interneurons
Dendrites
Axon
Axon
Sensory (afferent) neuron
Motor (efferent) neuron
Cell body
Axon
(central process)
Axon
(peripheral process)
Sensory
receptor
Effector
(muscle or gland)
Axon
terminal
201403 Ph.D. Jury HAM
Spinal cord
 Extends downward through
vertebral canal
 Begins at the foramen magnum
and terminates at the first and
second lumbar vertebrae (L1/L2)
interspace
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Brainstem
Spinal cord
Foramen
magnum
Cervical
enlargement
Vertebral
canal
Lumbar
enlargement
Conus
medullaris
Cauda
equina
Filum
terminale
Conus
medullaris
Lumbar
enlargement
Cervical
enlargement
201403 Ph.D. Jury HAM
Spinal Nerves
ALL are mixed nerves
(except the first pair)
31 pairs of spinal nerves:
 8 cervical nerves
(C1 to C8)
 12 thoracic nerves
(T1 to T12)
 5 lumbar nerves
(L1 to L5)
 5 sacral nerves
(S1 to S5)
 1 coccygeal nerve
(Co or Cc)
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Cauda equina
C1
C2
C3
C4
C5
C6
C7
C8
T1
T2
T3
T4
T5
T6
T7
T8
T9
T10
T11
T12
L1
L2
L3
L4
L5
S2
S3
S4
S1
S5
Co
Posterior
view
Cervical
nerves
Thoracic
nerves
Lumbar
nerves
Sacral
nerves
Coccygeal
nerve
Notes!!
Cervical spinal nerves
exit from above the
respective vertebra..
Spinal nerve R1
from above C1
Spinal nerve R2
from between C1&C2
201403 Ph.D. Jury HAM
Spinal Nerves continued
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
201403 Ph.D. Jury HAM
Autonomic Neurotransmitters
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Brain
Postganglionic fiber (axon)
Preganglionic fiber (axon)
Ganglion
Sympathetic neurons
ACh = acetylcholine (cholinergic)
NE = norepinephrine (adrenergic)
ACh
ACh
ACh
ACh
ACh ACh
NE
NE
Cranial
parasympathetic
neurons
Sacral
parasympathetic
neurons
Collateral
ganglion
Paravertebral
ganglion
Visceral
effectors
201403
Sympathetic Division
Ph.D. Jury HAM
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Lacrimal gland
Skin
Eye
Blood vessels
Heart
Lungs
Adrenal gland
Kidney
UterusPenis
Liver
Stomach
Gallbladder
Pancreas
Ovary
Scrotum
Small intestine
Large intestine
Trachea
Parotid gland,
submandibular and
sublingual glands
Urinary
bladder
Preganglionic
neuron
Postganglionic
neuron
Sympathetic
chain ganglia
Inferior
mesenteric
ganglion
Spinal
cord
Superior
mesenteric
ganglion
Celiac
ganglion
Fibers to
skin, blood vessels,
and adipose tissue
Celiac and
pulmonary
plexuses
201403
Parasympathetic Division
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Heart
Trachea
Lung
Gallbladder
Liver
Stomach
Spleen
Pancreas
Small intestine
Large intestine
Kidney
UterusScrotum
Otic ganglion
Ciliary ganglion Eye
Penis Ovary
Sphenopalatine
ganglion
Cranial
nerve III
Cranial
nerve
VII
Submandibular
ganglion
Cranial
nerve IX
Cranial nerve X
(Vagus)
Cardiac and
pulmonary
plexuses
Celiac
plexus
Superior
hypogastric
plexus
Inferior
hypogastric
plexus
Spinal
cord
Pelvic
nerves
Urinary
bladder
Parotid
gland
Submandibular
and sublingual
glands
Lacrimal gland
Preganglionic
neuron
Postganglionic
neuron
Ph.D. Jury HAM
201403
Dermatom
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Ph.D. Jury HAM
C2
C3
C4
C5
C6
T1
C6
C7
S2
S3
C8
L1
L2
L3
L4
L5
T12
T1
S1
S5
C0
S4
S3
S2
S1
L5
L4
L3
L2
L1
L5
L1
C8
T1
T12
C7
C6
C5
C4
C3
C2
201403
Cranial Nerve
Ph.D. Jury HAM
201403
Cranial Nerve
Ph.D. Jury HAM
201403
Cranial Nerve
Ph.D. Jury HAM
201403
Cranial Nerve
Ph.D. Jury HAM
CN I Olfactory Olfactory
epithelium
Smell
CN II Optic Retina Vision
CN III Occulomotor Midbrain Eye movement;
accommodation
CN IV Trochlear Midbrain Eye movement
(superior oblique)
CN V Trigeminal Pons Sensation to face;
chewing
CN VI Abducens Pons Eye movement
( lateral rectus)
CN VII Facial Pons Facial expression;
taste to anterior
2/3 of tongue
CN VIII Vestibulocochlear Pons Hearing &
balance
CN IX Glossopharyngeal Medulla Salivation;
swallowing; taste
to posterior 1/3
of tongue
CN X Vagus Medulla Digestion; taste
to pharynx
CN XI Accessory Medulla Movement of
trapezius & SCM
CN XII Hypoglossal Medulla Movement of
tongue
201403
Brain Protection
Ph.D. Jury HAM
Bone
Meninges
CSF
Cerebrpspinal
fluid
Blood
Brain
Barrier
201403
Spinal cord Protection
Ph.D. Jury HAM
201403
Cerebrospinal Fluid
Ph.D. Jury HAM
201403
Cerebrospinal Fluid
Ph.D. Jury HAM
201403
Cerebrospinal Fluid
Ph.D. Jury HAM
201403
QUIZ
Ph.D. Jury HAM
Does a bigger brain mean
you are smarter?
The debate is still on.
It seems that the higher brain
to body mass an animal has,
the smarter it is.
Einstein's overall brain was a
normal size, but the specific
portion known for spatial
intelligence was wider and
had a unique anatomy.
Ha! Ha!
201403
Brain/Body size relationship
Ph.D. Jury HAM
201403
Brain/Body size relationship
Ph.D. Jury HAM
201403
Evolution of the Brain
Ph.D. Jury HAM
Ph.D. Jury HAM

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기초신경해부학 chap 1. 신경계

  • 1. Basic Neuro Anatomy Chap1. Brain & Body Ph.D. Jury Ham
  • 2. Nerves system 1. CNS Brain Spinal cord 2. PNS Somatic Nerve Autonomic Nerve 201403 Ph.D. Jury HAM
  • 3. A few definitions 201403 Ph.D. Jury HAM A few Definitions Locations in the Brain  Described relative to neuraxis - an imaginary line drawn through the spinal cord up to the front of the brain  The front end is anterior  The back end is posterior  The terms rostral (toward the head) and caudal ( toward the tail) are also used when referring to pa rts of the brain
  • 4. Dorsal (back) refers to the top of the head and the back The ventral (front) surface faces the ground. These directions are somewhat more complicated in humans because our neuraxis bends, so that the top of the head is now perpendicular to the back. 201403 Ph.D. Jury HAM A few Definitions Locations in the Brain
  • 5. 201403 Ph.D. Jury HAM The Neuraxis Anterior Posterior Dorsal Ventral
  • 6. 201403 Ph.D. Jury HAM The Neuraxis Anterior Posterial DorsalVentral superior inferior
  • 7. Lateral means to the side (away from the neuraxis) Medial (or mesial) means toward the middle (towards the neuraxis) Proximal: Areas of the brain that are near to one another Distal: Areas that are far from one another 201403 Ph.D. Jury HAM A few Definitions Locations in the Brain
  • 8. 201403 Ph.D. Jury HAM A few Definitions Locations in the Brain  Ipsilateral refers to structures on the same side of the body  E.g. the olfactory bulbs send ipsilateral conne ctions to the brain - the right bulb connects t o the right hemisphere, and the left bulb con nects to the left hemisphere  Contralateral refers to structures on opposite sides of the body  E.g. the left motor strip connects to the right side of the body
  • 9. 201403 Ph.D. Jury HAM A few Definitions Slices of the Brain fornix
  • 10. 201403 Ph.D. Jury HAM Division of nervous system CNS Central Nervous System Brain Spinal cord PNS Peripheral Nervous System Cranial nerves Spinal nerves Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Brain Spinal cord Spinal nerves Cranial nerves
  • 11. 201403 Ph.D. Jury HAM Division of nervous system Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Sensory division Sensory receptors Motor division Skeletal muscle Brain Spinal cord Spinal nerves Cranial nerves Central Nervous System (brain and spinal cord) Peripheral Nervous System (cranial and spinal nerves) Smooth m. Cardiac m. Glands Autonomic Nervous System Somatic Nervous System
  • 12. 201403 Ph.D. Jury HAM Division of nervous system Grey matter White matter CNS PNS Nuclei Tracts Ganglia Nerve
  • 13. 201403 Ph.D. Jury HAM Division of nervous system Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Receptor Sensory or afferent neuron Motor or efferent neuronCentral Nervous System Effector (muscle or gland)
  • 14. 201403 Ph.D. Jury HAM Classification of Neurons Functional difference Central nervous system Peripheral nervous system Cell body Interneurons Dendrites Axon Axon Sensory (afferent) neuron Motor (efferent) neuron Cell body Axon (central process) Axon (peripheral process) Sensory receptor Effector (muscle or gland) Axon terminal
  • 15. 201403 Ph.D. Jury HAM Spinal cord  Extends downward through vertebral canal  Begins at the foramen magnum and terminates at the first and second lumbar vertebrae (L1/L2) interspace Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Brainstem Spinal cord Foramen magnum Cervical enlargement Vertebral canal Lumbar enlargement Conus medullaris Cauda equina Filum terminale Conus medullaris Lumbar enlargement Cervical enlargement
  • 16. 201403 Ph.D. Jury HAM Spinal Nerves ALL are mixed nerves (except the first pair) 31 pairs of spinal nerves:  8 cervical nerves (C1 to C8)  12 thoracic nerves (T1 to T12)  5 lumbar nerves (L1 to L5)  5 sacral nerves (S1 to S5)  1 coccygeal nerve (Co or Cc) Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Cauda equina C1 C2 C3 C4 C5 C6 C7 C8 T1 T2 T3 T4 T5 T6 T7 T8 T9 T10 T11 T12 L1 L2 L3 L4 L5 S2 S3 S4 S1 S5 Co Posterior view Cervical nerves Thoracic nerves Lumbar nerves Sacral nerves Coccygeal nerve
  • 17. Notes!! Cervical spinal nerves exit from above the respective vertebra.. Spinal nerve R1 from above C1 Spinal nerve R2 from between C1&C2 201403 Ph.D. Jury HAM Spinal Nerves continued Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 18. 201403 Ph.D. Jury HAM Autonomic Neurotransmitters Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Brain Postganglionic fiber (axon) Preganglionic fiber (axon) Ganglion Sympathetic neurons ACh = acetylcholine (cholinergic) NE = norepinephrine (adrenergic) ACh ACh ACh ACh ACh ACh NE NE Cranial parasympathetic neurons Sacral parasympathetic neurons Collateral ganglion Paravertebral ganglion Visceral effectors
  • 19. 201403 Sympathetic Division Ph.D. Jury HAM Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Lacrimal gland Skin Eye Blood vessels Heart Lungs Adrenal gland Kidney UterusPenis Liver Stomach Gallbladder Pancreas Ovary Scrotum Small intestine Large intestine Trachea Parotid gland, submandibular and sublingual glands Urinary bladder Preganglionic neuron Postganglionic neuron Sympathetic chain ganglia Inferior mesenteric ganglion Spinal cord Superior mesenteric ganglion Celiac ganglion Fibers to skin, blood vessels, and adipose tissue Celiac and pulmonary plexuses
  • 20. 201403 Parasympathetic Division Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Heart Trachea Lung Gallbladder Liver Stomach Spleen Pancreas Small intestine Large intestine Kidney UterusScrotum Otic ganglion Ciliary ganglion Eye Penis Ovary Sphenopalatine ganglion Cranial nerve III Cranial nerve VII Submandibular ganglion Cranial nerve IX Cranial nerve X (Vagus) Cardiac and pulmonary plexuses Celiac plexus Superior hypogastric plexus Inferior hypogastric plexus Spinal cord Pelvic nerves Urinary bladder Parotid gland Submandibular and sublingual glands Lacrimal gland Preganglionic neuron Postganglionic neuron Ph.D. Jury HAM
  • 21. 201403 Dermatom Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Ph.D. Jury HAM C2 C3 C4 C5 C6 T1 C6 C7 S2 S3 C8 L1 L2 L3 L4 L5 T12 T1 S1 S5 C0 S4 S3 S2 S1 L5 L4 L3 L2 L1 L5 L1 C8 T1 T12 C7 C6 C5 C4 C3 C2
  • 25. 201403 Cranial Nerve Ph.D. Jury HAM CN I Olfactory Olfactory epithelium Smell CN II Optic Retina Vision CN III Occulomotor Midbrain Eye movement; accommodation CN IV Trochlear Midbrain Eye movement (superior oblique) CN V Trigeminal Pons Sensation to face; chewing CN VI Abducens Pons Eye movement ( lateral rectus) CN VII Facial Pons Facial expression; taste to anterior 2/3 of tongue CN VIII Vestibulocochlear Pons Hearing & balance CN IX Glossopharyngeal Medulla Salivation; swallowing; taste to posterior 1/3 of tongue CN X Vagus Medulla Digestion; taste to pharynx CN XI Accessory Medulla Movement of trapezius & SCM CN XII Hypoglossal Medulla Movement of tongue
  • 26. 201403 Brain Protection Ph.D. Jury HAM Bone Meninges CSF Cerebrpspinal fluid Blood Brain Barrier
  • 31. 201403 QUIZ Ph.D. Jury HAM Does a bigger brain mean you are smarter? The debate is still on. It seems that the higher brain to body mass an animal has, the smarter it is. Einstein's overall brain was a normal size, but the specific portion known for spatial intelligence was wider and had a unique anatomy. Ha! Ha!
  • 34. 201403 Evolution of the Brain Ph.D. Jury HAM