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TYPES OF GENE ACTION AND MODIFICATION OF MENDELIAN RATIOS ,[object Object],[object Object]
[object Object],[object Object]
Complete dominance: Inheritance of black and red colour in cattle
Incomplete dominance ,[object Object],[object Object],[object Object]
 
[object Object],[object Object]
 
Codominance ,[object Object],[object Object]
[object Object]
Inheritance of ABO blood group in human P generation Female x Male  Phenotype blood group A blood group B Genotype I A /I A I B /I B Gametes  All I A All I B F 1  Genotypes  All I A /I B F 1  Phenotypes All blood group AB Interbreeding F1 F 1  generation Female x Male  F 1  Phenotype blood group AB blood group AB F 1  Genotype I A /I B I A /I B F 1  Gametes  ½ I A , ½ I B ½ I A ,  ½  I B F 2  genotypes ¼ I A /I A ,    ½ I A /I B ¼ I B /I B F 2  Phenotypes ¼ blood group A ½ blood group AB ¼ blood group B F 2  Phenotypic ratio 1:2:1 for blood group A: blood group AB : blood group B
[object Object],[object Object]
 
Overdominance ,[object Object]
Gene interactions that produce new phenotypes ,[object Object],[object Object],[object Object]
 
 
Epistasis ,[object Object],[object Object],[object Object]
Agouti (banded) hair Agouti Non-agouti Eumelanin Phaeomelanin
 
Pleiotropy ,[object Object],[object Object],[object Object]
Sex-limited genes ,[object Object],[object Object]
 
Sex-influenced traits ,[object Object],[object Object]
Sex-linked genes ,[object Object],[object Object]
The inheritance of X-linked genes: red eyes and white eyes in  Drosophila melanogaster P generation parent 1 x  parent 2  Parental phenotype Female, red  - eyes Male, white eyes Parental genotype X w+ X w+ X w Y Gametes all X w+ ½ X w , ½ Y F 1 generation F 1 genotype ½ X w+ X w ,  ½ X w+ Y F 1 phenotype ½ female, red eyes ½ male, red eyes Interbreeding F 1 generation parent 1 x  parent 2  F 1 phenotype Female, red eyes Male, red eyes F 1 genotype X w+ X w X w+  Y F 1 Gametes ½ X w+ , ½  X w ½ X w+ , ½ Y
 
Age of onset ,[object Object],[object Object],[object Object]
Genotype x environment interaction ,[object Object]
(i) Genotypes A and B rank differently in the two environments
(ii) Genotypes A and B rank the same in the two environments i.e B is the best in both environment, but the advantage of B is much less in environment 2
Penetrance and Expressivity ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Essential genes and lethal alleles ,[object Object],[object Object],[object Object],[object Object]
 

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Gene action and modification of mendelian

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  • 3. Complete dominance: Inheritance of black and red colour in cattle
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  • 10. Inheritance of ABO blood group in human P generation Female x Male Phenotype blood group A blood group B Genotype I A /I A I B /I B Gametes All I A All I B F 1 Genotypes All I A /I B F 1 Phenotypes All blood group AB Interbreeding F1 F 1 generation Female x Male F 1 Phenotype blood group AB blood group AB F 1 Genotype I A /I B I A /I B F 1 Gametes ½ I A , ½ I B ½ I A , ½ I B F 2 genotypes ¼ I A /I A , ½ I A /I B ¼ I B /I B F 2 Phenotypes ¼ blood group A ½ blood group AB ¼ blood group B F 2 Phenotypic ratio 1:2:1 for blood group A: blood group AB : blood group B
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  • 18. Agouti (banded) hair Agouti Non-agouti Eumelanin Phaeomelanin
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  • 25. The inheritance of X-linked genes: red eyes and white eyes in Drosophila melanogaster P generation parent 1 x parent 2 Parental phenotype Female, red - eyes Male, white eyes Parental genotype X w+ X w+ X w Y Gametes all X w+ ½ X w , ½ Y F 1 generation F 1 genotype ½ X w+ X w , ½ X w+ Y F 1 phenotype ½ female, red eyes ½ male, red eyes Interbreeding F 1 generation parent 1 x parent 2 F 1 phenotype Female, red eyes Male, red eyes F 1 genotype X w+ X w X w+ Y F 1 Gametes ½ X w+ , ½ X w ½ X w+ , ½ Y
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  • 29. (i) Genotypes A and B rank differently in the two environments
  • 30. (ii) Genotypes A and B rank the same in the two environments i.e B is the best in both environment, but the advantage of B is much less in environment 2
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