ENGLISH
Clinic case
ENGLISH
Clinic case
Saturday 28th 2015Saturday 28th 2015
 Irene Marleny Soriano
Villalobos
 Jerson André Vigo
Rabanal
 Carlos Felipe Chero
Gallardo
 Irene Marleny Soriano
Villalobos
 Jerson André Vigo
Rabanal
 Carlos Felipe Chero
Gallardo
A male patient of 48 years old
arrive to the emergency service
to the Regional Hospital; he
comes with his friends; the
patient refere that they was
playing soccer and he felt a
pain in the chest for three
opportunities; the first two times
the pain was calmed when he
stopped to play but in the three
time do not calm for this motive
he comes to the hospital.
LIFE STILE
The patient smoke 5 cigars for
day and dont have much fisic
activity; he only plays soccer
one time at the month.
FAMILIARY ANTECEDENTS
His father died at 55 years
caused for a hearth attack
The patient indicate that
the pain is behind the
sternum and the kind of the
pain is oppressive; and the
pain is reflected in the left
arm too; this symptom start
one hour ago.
Fisic Exam
Arterial Pressure: 130/89 mmHg
Heartbeat: 80 lpm
Respiratory Frecuency: 22 rfm
Temperature: 36,5 ºC
Stature: 1,60 mt.
Weight: 85 kg
Abdominal Circunferency: 110cm
Body mass index: 32,2
Acts:
• Patient male
• Arrive to Emergency service of the Regional Hospital.
• Comes accompanied with his friends
• He was playing soccer
• Smoker and sedentary life.
• His father died for a head attack.
Health Problems:
1.- pain in the chest of kind oppresive
2.- the pain is reflected in the left arm
3.- Obesity
4.- Arterial Hypertension
5.- Style of life unhealthy
Case AnalysisCase Analysis
Associated factorsAssociated factors
 Age
 Sex
 Family history
 Age
 Sex
 Family history
 Tobacco
 Hypercholesterolemia
 Hypertension
 Diabetes
 Obesity
 Alcohol
 Emotional distress
 Tobacco
 Hypercholesterolemia
 Hypertension
 Diabetes
 Obesity
 Alcohol
 Emotional distress
Unchangeable Modifiable
AFFECTED STRUCTURE
THE HEART
• Is a muscular organ that is the main part of
the circulatory system, It is the responsible
for pumping blood to all the parts of the
body
• Is divided in 4 cavities; this cavities are left
and right atrium, left and right ventricles ;
the part of the right heart have blood with
few oxygen and the part of the left heart
have blood with so much oxygen.
• Is an self controlled organ because it have
some muscular fibres that have
modification and generate electric pulses.
the heart have two fases; the first one called sistole
(contraction) and the other called diastole
(chamber filling)
The irrigation of the heart is by the coronary arteries; this
arteries are originated in the ascendant part of the aorta
artery; specifically in the aortic sinuses or sinuses of Valsalva
both the right and left side.
The coronary arteries are two : the right coronary and the
left coronary
 The left coronary is divided in descending anterior artery
and the circunfleja artery. This arteries are responsible of
the irrigation to the anterior and lateral part of the left
ventricle.
 The right coronary is divided in descending posterior
artery that is the responsible of the irrigation of the lower
wall of the heart
There are different types of coronary diseases but the most
frequent and most clinically relevant is coronary
atherosclerosis and it can be produce to ischemic heart
disease.
Male patient
48 years
Myocardial
infarction
Blood flow Poor blood
supply
Tissue
damage
Obstruction
Atheroma
Personal
record
Obesity
Excessive fat intake
LDL
HDL
Chest
pain
Oppressive
Retroesternal
Referred to
left arm
Emergency
Sick time: 1 hour
Endothelium
of arteries
Decreased
tissue
oxygen
Peripheral
chemoreceptors
Pulmonary
ventilation
Activation of
vagal
receptores
(acetylcholine)
Cardiac
contractility
Sweat glands
(diaphoresis)
Acute ManagementAcute Management
 Oxygen therapy
 GTN (½ sublingual tab)
 Aspirin 300mg
 IV morphine 2.5~5mg + IV metoclopramide 10mg
 Oxygen therapy
 GTN (½ sublingual tab)
 Aspirin 300mg
 IV morphine 2.5~5mg + IV metoclopramide 10mg
Hospital ManagementHospital Management
Aspirin, GTN, morphine, oxygen if not
already given
Monitor oximetry, BP, continuous ECG
12 lead ECG, IV access, cardiac
enzyme
Aspirin, GTN, morphine, oxygen if not
already given
Monitor oximetry, BP, continuous ECG
12 lead ECG, IV access, cardiac
enzyme
STEMISTEMI
 Reperfuse ASAP (within 12hrs of onset of sx – i.e. before MI is
complete):
 Antiplatelet therapy (aspirin and clopidogrel ± GPIIb/IIIa
inhibitor)
 Anticoagulation agent (unfractionated heparin or LMWH)
Immediate PCI or fibrinolytic therapy
– PCI has higher reperfusion rate and is better if pt present > 1hr
but thrombolysis is gold standard if pt arrive within an hour
 Reperfuse ASAP (within 12hrs of onset of sx – i.e. before MI is
complete):
 Antiplatelet therapy (aspirin and clopidogrel ± GPIIb/IIIa
inhibitor)
 Anticoagulation agent (unfractionated heparin or LMWH)
Immediate PCI or fibrinolytic therapy
– PCI has higher reperfusion rate and is better if pt present > 1hr
but thrombolysis is gold standard if pt arrive within an hour
STEMISTEMI
 Subsequent management (start during this hospital admission)
 Statins, aspirin and clopidogrel, ACEI (or ARB), β-blocker (if CI then
CCB)
 Nitrates PRN
 Cardiac rehabilitation
 Antiplatelet post stent
 Aspirin for life
 Clopidogrel for at least 6wks for metal stent
 Subsequent management (start during this hospital admission)
 Statins, aspirin and clopidogrel, ACEI (or ARB), β-blocker (if CI then
CCB)
 Nitrates PRN
 Cardiac rehabilitation
 Antiplatelet post stent
 Aspirin for life
 Clopidogrel for at least 6wks for metal stent
UA and NSTEMIUA and NSTEMI
 Stabilize acute coronary lesion
 Anti-platelet (aspirin and clopidogrel ± GPIIb/IIIa
inhibitor)
 Anti-thrombin (UFH or LMWH)
 Anti-ischaemia (β-blocker if CI then CCB, consider
nitrates, morphine)
 High risk – urgent angiography ± PCI
 Low risk – arrange stress tests
 Subsequent management (start during this hospital
admission)
 Statins, aspirin and clopidogrel, ACEI (or ARB), β-
blocker (if CI then CCB)
 Nitrates PRN
 Cardiac rehabilitation
 Stabilize acute coronary lesion
 Anti-platelet (aspirin and clopidogrel ± GPIIb/IIIa
inhibitor)
 Anti-thrombin (UFH or LMWH)
 Anti-ischaemia (β-blocker if CI then CCB, consider
nitrates, morphine)
 High risk – urgent angiography ± PCI
 Low risk – arrange stress tests
 Subsequent management (start during this hospital
admission)
 Statins, aspirin and clopidogrel, ACEI (or ARB), β-
blocker (if CI then CCB)
 Nitrates PRN
 Cardiac rehabilitation
Diet Physical activity Tabacco
Control
cardiovascular risk
What can I do to avoid
a myocardial infarction?

MYOCARDIAL INFARCTION

  • 1.
    ENGLISH Clinic case ENGLISH Clinic case Saturday28th 2015Saturday 28th 2015  Irene Marleny Soriano Villalobos  Jerson André Vigo Rabanal  Carlos Felipe Chero Gallardo  Irene Marleny Soriano Villalobos  Jerson André Vigo Rabanal  Carlos Felipe Chero Gallardo
  • 2.
    A male patientof 48 years old arrive to the emergency service to the Regional Hospital; he comes with his friends; the patient refere that they was playing soccer and he felt a pain in the chest for three opportunities; the first two times the pain was calmed when he stopped to play but in the three time do not calm for this motive he comes to the hospital.
  • 3.
    LIFE STILE The patientsmoke 5 cigars for day and dont have much fisic activity; he only plays soccer one time at the month. FAMILIARY ANTECEDENTS His father died at 55 years caused for a hearth attack The patient indicate that the pain is behind the sternum and the kind of the pain is oppressive; and the pain is reflected in the left arm too; this symptom start one hour ago.
  • 4.
    Fisic Exam Arterial Pressure:130/89 mmHg Heartbeat: 80 lpm Respiratory Frecuency: 22 rfm Temperature: 36,5 ºC Stature: 1,60 mt. Weight: 85 kg Abdominal Circunferency: 110cm Body mass index: 32,2
  • 5.
    Acts: • Patient male •Arrive to Emergency service of the Regional Hospital. • Comes accompanied with his friends • He was playing soccer • Smoker and sedentary life. • His father died for a head attack. Health Problems: 1.- pain in the chest of kind oppresive 2.- the pain is reflected in the left arm 3.- Obesity 4.- Arterial Hypertension 5.- Style of life unhealthy Case AnalysisCase Analysis
  • 6.
    Associated factorsAssociated factors Age  Sex  Family history  Age  Sex  Family history  Tobacco  Hypercholesterolemia  Hypertension  Diabetes  Obesity  Alcohol  Emotional distress  Tobacco  Hypercholesterolemia  Hypertension  Diabetes  Obesity  Alcohol  Emotional distress Unchangeable Modifiable
  • 7.
    AFFECTED STRUCTURE THE HEART •Is a muscular organ that is the main part of the circulatory system, It is the responsible for pumping blood to all the parts of the body • Is divided in 4 cavities; this cavities are left and right atrium, left and right ventricles ; the part of the right heart have blood with few oxygen and the part of the left heart have blood with so much oxygen. • Is an self controlled organ because it have some muscular fibres that have modification and generate electric pulses. the heart have two fases; the first one called sistole (contraction) and the other called diastole (chamber filling)
  • 8.
    The irrigation ofthe heart is by the coronary arteries; this arteries are originated in the ascendant part of the aorta artery; specifically in the aortic sinuses or sinuses of Valsalva both the right and left side. The coronary arteries are two : the right coronary and the left coronary  The left coronary is divided in descending anterior artery and the circunfleja artery. This arteries are responsible of the irrigation to the anterior and lateral part of the left ventricle.  The right coronary is divided in descending posterior artery that is the responsible of the irrigation of the lower wall of the heart There are different types of coronary diseases but the most frequent and most clinically relevant is coronary atherosclerosis and it can be produce to ischemic heart disease.
  • 10.
    Male patient 48 years Myocardial infarction Bloodflow Poor blood supply Tissue damage Obstruction Atheroma Personal record Obesity Excessive fat intake LDL HDL Chest pain Oppressive Retroesternal Referred to left arm Emergency Sick time: 1 hour Endothelium of arteries
  • 11.
  • 12.
    Acute ManagementAcute Management Oxygen therapy  GTN (½ sublingual tab)  Aspirin 300mg  IV morphine 2.5~5mg + IV metoclopramide 10mg  Oxygen therapy  GTN (½ sublingual tab)  Aspirin 300mg  IV morphine 2.5~5mg + IV metoclopramide 10mg
  • 13.
    Hospital ManagementHospital Management Aspirin,GTN, morphine, oxygen if not already given Monitor oximetry, BP, continuous ECG 12 lead ECG, IV access, cardiac enzyme Aspirin, GTN, morphine, oxygen if not already given Monitor oximetry, BP, continuous ECG 12 lead ECG, IV access, cardiac enzyme
  • 14.
    STEMISTEMI  Reperfuse ASAP(within 12hrs of onset of sx – i.e. before MI is complete):  Antiplatelet therapy (aspirin and clopidogrel ± GPIIb/IIIa inhibitor)  Anticoagulation agent (unfractionated heparin or LMWH) Immediate PCI or fibrinolytic therapy – PCI has higher reperfusion rate and is better if pt present > 1hr but thrombolysis is gold standard if pt arrive within an hour  Reperfuse ASAP (within 12hrs of onset of sx – i.e. before MI is complete):  Antiplatelet therapy (aspirin and clopidogrel ± GPIIb/IIIa inhibitor)  Anticoagulation agent (unfractionated heparin or LMWH) Immediate PCI or fibrinolytic therapy – PCI has higher reperfusion rate and is better if pt present > 1hr but thrombolysis is gold standard if pt arrive within an hour
  • 15.
    STEMISTEMI  Subsequent management(start during this hospital admission)  Statins, aspirin and clopidogrel, ACEI (or ARB), β-blocker (if CI then CCB)  Nitrates PRN  Cardiac rehabilitation  Antiplatelet post stent  Aspirin for life  Clopidogrel for at least 6wks for metal stent  Subsequent management (start during this hospital admission)  Statins, aspirin and clopidogrel, ACEI (or ARB), β-blocker (if CI then CCB)  Nitrates PRN  Cardiac rehabilitation  Antiplatelet post stent  Aspirin for life  Clopidogrel for at least 6wks for metal stent
  • 16.
    UA and NSTEMIUAand NSTEMI  Stabilize acute coronary lesion  Anti-platelet (aspirin and clopidogrel ± GPIIb/IIIa inhibitor)  Anti-thrombin (UFH or LMWH)  Anti-ischaemia (β-blocker if CI then CCB, consider nitrates, morphine)  High risk – urgent angiography ± PCI  Low risk – arrange stress tests  Subsequent management (start during this hospital admission)  Statins, aspirin and clopidogrel, ACEI (or ARB), β- blocker (if CI then CCB)  Nitrates PRN  Cardiac rehabilitation  Stabilize acute coronary lesion  Anti-platelet (aspirin and clopidogrel ± GPIIb/IIIa inhibitor)  Anti-thrombin (UFH or LMWH)  Anti-ischaemia (β-blocker if CI then CCB, consider nitrates, morphine)  High risk – urgent angiography ± PCI  Low risk – arrange stress tests  Subsequent management (start during this hospital admission)  Statins, aspirin and clopidogrel, ACEI (or ARB), β- blocker (if CI then CCB)  Nitrates PRN  Cardiac rehabilitation
  • 17.
    Diet Physical activityTabacco Control cardiovascular risk What can I do to avoid a myocardial infarction?