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uetator Periodic Table Question 6 of 30 Incorrect Incorrect DA Sapling Learning sponsible
syndrome is anX-inked, recessive condition caused by mutation of the HPRT1 muscle
movements, The syndrome is characterized byjuvenile-onset gout, in and behavioral disorders. A
mother and father have a young daughter who was diagnosed with Lesch-Nyhan syndrome. No
one in the with family was ever diagnosed the The maternal grandfather was diagnosed
syndrome, but neither one of her parents was diagnosed with condition. Select all the
descriptions that could explain how their daughter inherited Lesch-Nyhan syndrome. The
daughter could not have Nyhan because her maternal grandparents did not have disease. The girl
must have acquired the disease through a random mutation. The daughter inherited two
xchromosomes with the of the mothers X mutation. Nondisjunction chromosome chromosomes
occurred during meiosis, and the daughter inherited from her father. The father did not contribute
a sex chromosome to his daughter due to nondisjunction of the sex chromosomes. The daughter
is xo and her only X chromosome came from her mother, who was a O The d from her father,
who was a carrier. camies the Lesch-Nyhan mutation and was Her inherited There is a hint
available! bottom divider bar. Click on the divider bar again to hide the hint. Previous ® Give
Up & View solution Check Answer 0 Next HExi Hint
Solution
1) the hint here is that the mother's maternal was diagnosed with Lesch-Nyhan syndrome. Since
it is an X-chromosome related disease, it is very rare to have females affected by it. If a girl has
LNS, she must have inherited two effected X chromosomes from each parent. Also, one third of
cases arise from new mutations even when there is no family history of any. So the first two
points are the possible reasons for the girls to have LNS.

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  • 1. uetator Periodic Table Question 6 of 30 Incorrect Incorrect DA Sapling Learning sponsible syndrome is anX-inked, recessive condition caused by mutation of the HPRT1 muscle movements, The syndrome is characterized byjuvenile-onset gout, in and behavioral disorders. A mother and father have a young daughter who was diagnosed with Lesch-Nyhan syndrome. No one in the with family was ever diagnosed the The maternal grandfather was diagnosed syndrome, but neither one of her parents was diagnosed with condition. Select all the descriptions that could explain how their daughter inherited Lesch-Nyhan syndrome. The daughter could not have Nyhan because her maternal grandparents did not have disease. The girl must have acquired the disease through a random mutation. The daughter inherited two xchromosomes with the of the mothers X mutation. Nondisjunction chromosome chromosomes occurred during meiosis, and the daughter inherited from her father. The father did not contribute a sex chromosome to his daughter due to nondisjunction of the sex chromosomes. The daughter is xo and her only X chromosome came from her mother, who was a O The d from her father, who was a carrier. camies the Lesch-Nyhan mutation and was Her inherited There is a hint available! bottom divider bar. Click on the divider bar again to hide the hint. Previous ® Give Up & View solution Check Answer 0 Next HExi Hint Solution 1) the hint here is that the mother's maternal was diagnosed with Lesch-Nyhan syndrome. Since it is an X-chromosome related disease, it is very rare to have females affected by it. If a girl has LNS, she must have inherited two effected X chromosomes from each parent. Also, one third of cases arise from new mutations even when there is no family history of any. So the first two points are the possible reasons for the girls to have LNS.