Radiation Induced Hypoplasia of the Mandible and Retarded Tooth Development /orthodontic courses by Indian dental academy /orthodontic courses by Indian dental academy
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Radiation Induced Hypoplasia of the Mandible and Retarded Tooth Development /orthodontic courses by Indian dental academy /orthodontic courses by Indian dental academy
- 1. www.indiandentalacademy.com INDIAN DENTAL ACADEMY Leader in continuing Dental Education
- 7. SOFTTISSUE EXAMN.: Generalized gingival inflammation www.indiandentalacademy.com
- 11. Hypoplasia of the mandible Condylar hypoplasia Deep sigmoid notch Reduced vertical height of the ramus Stunted mand. Premolar and Permanent Molar Roots Grossly destructed right mand. Permanent First Molar www.indiandentalacademy.com
- 21. DOSE RADIATION EFFECTS 4 – 16 Gy Radiation dosages to the tooth buds and mandibular growth centre causes premature apical closure and hypoplasia of roots of teeth. (Lines et al., 1979) 10 Gy Histologically, taste buds showed signs of degeneration and atrophy (Conger, 1973) 15 Gy Within 3 days after irradiation with a single dose, a decrease in salivary flow of nearly 50% can be observed (Vissink et al., 1990; Peter et al., 1995; Coppes et al., 1997 a, b, 2001; Zielstra et al., 2000) 24 Gy Interruption in both tooth formation and bone development {Tasaka H, ed. Encyclopedia of clinical radiology. Tokyo: Nakayama Syoten, 1985: 277 -95 (vol 33)} www.indiandentalacademy.com
- 22. DOSE RADIATION EFFECTS < 30 Gy Damage to salivary gland is reversible to certain level (Dreyer et al., 1989) 30 Gy Taste sensation decreases exponentially , after which it becomes virtually absent (Conger ,1973) 60 Gy Extent of reduced flow is dose dependent and reaches essentially zero. (White SC and Pharaoh MJ, Oral Radiology, 5th ed., 2004) >65 Gy Spontaneous osteoradionecrosis reported to occur in almost 35 % of cases (Murray et al., 1980a; Marx, 1983a,b; Marx and Johnson, 1987; Kluth et al., 1988; Constantino et al., 1995; Glanzmann and Grätz, 1995; Curi and Dib, 1997; Tong et al., 1999; Thorn et al., 2000) >75 Gy Extensive degeneration of acini, along with inflammation and fibrosis in the interstitium (Dreyer et al., 1989) www.indiandentalacademy.com
- 29. Prevention or reduction to a minimum of unwanted side effects is possible and should be an integral part of head and neck cancer treatment. With the implementation of new radiation schedules in head and neck radiotherapy, late- radiation effects can probably be minimized. Hyperfractionation Accelerated fractionation 3D conformal radiotherapy Intensity-modulated radiotherapy www.indiandentalacademy.com