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International Journal of Trend in Scientific Research and Development (IJTSRD)
Volume 6 Issue 1, November-December 2021 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470
@ IJTSRD | Unique Paper ID – IJTSRD48032 | Volume – 6 | Issue – 1 | Nov-Dec 2021 Page 1327
Role of Homeopathy in Management of GERD
Dr. Nidhi Dave
MD (Hom), Consultant Homoeopathic Physician, Sainath Hospital, Ahmedabad
Attached to Ahmedabad Homoeopathic Medical College, Parul University
ABSTRACT
Gastroesophageal reflux disease (GERD) is a common disease of the
gastrointestinal tract. GERD is defined as symptoms or mucosal
damage as a result of abnormal reflux of gastric contents into the
oesophagus or beyond.
GER (Gastro-oesophageal reflux) is a normal physiologic process in
which there will be retrograde movement of gastric contents from the
stomach to the oesophagus. GER is not a disease. It occurs several
times a day without mucosal damage or symptoms. GERD is caused
by failure of anti-reflux barrier. GERD occurs when stomach
contents move to the oesophagus effortlessly which cause the reflux
symptoms like heartburn and regurgitation. It is a multifactorial
process.
KEYWORDS: Gastro-oesophageal reflux, Gastro-oesophageal reflux
disorder, Homoeopathy, GERD, Homoeopathic management, Reflux
oesophagitis
How to cite this paper: Dr. Nidhi Dave
"Role of Homeopathy in Management of
GERD" Published
in International
Journal of Trend in
Scientific Research
and Development
(ijtsrd), ISSN: 2456-
6470, Volume-6 |
Issue-1, December
2021, pp.1327-1336, URL:
www.ijtsrd.com/papers/ijtsrd48032.pdf
Copyright © 2021 by author (s) and
International Journal of Trend in
Scientific Research and Development
Journal. This is an
Open Access article
distributed under the
terms of the Creative Commons
Attribution License (CC BY 4.0)
(http://creativecommons.org/licenses/by/4.0)
INTRODUCTION
The term Gastroesophageal refers to the stomach and
oesophagus. Reflux means to flow back or return.
Therefore, gastroesophageal reflux is the return of the
stomach's contents back up into the oesophagus.
Gastroesophageal reflux disease (GERD) is a
common disease of the gastrointestinal tract. GERD is
defined as symptoms or mucosal damage as a result
of abnormal reflux of gastric contents into the
oesophagus or beyond.
GER (Gastro-oesophageal reflux) is a normal
physiologic process in which there will be retrograde
movement of gastric contents from the stomach to the
oesophagus. GER is not a disease. It occurs several
times a day without mucosal damage or symptoms.
GERD is caused by failure of anti-reflux barrier.
GERD occurs when stomach contents move to the
oesophagus effortlessly which cause the reflux
symptoms like heartburn and regurgitation. It is a
multifactorial process.
GERD affects the quality of life. Using endoscopy,
GERD can be classified into non erosive reflux
disease and erosive esophagitis. According to Los
Angeles classification erosive esophagitis is graded
from A-D. It has a wide variety of clinical
presentations ranging from gastrointestinal (common)
to extra-gastrointestinal (uncommon) symptoms.
Common gastrointestinal symptoms classical triad of
symptoms is retrosternal burning pain (heartburn),
epigastric pain (sometimes radiating through to the
back) and regurgitation. Extra gastrointestinal
symptoms are bronchial asthma, laryngitis,
hoarseness of voice, chronic cough, sore throat and
dental erosions. Diverse studies on various population
and lifestyle background had been reported in
previous literature, however the data were few from
our part of the country. Henceforth, warranting more
studies representing the facts from our province of the
country.
Furthermore, longstanding and untreated GERD leads
to morbid complications such as oesophageal ulcer,
Barrett’s oesophagus and oesophageal stricture.
However, variable inference had been postulated
regarding the association of clinical, lifestyle and
endoscopic characteristics associated with
complications of GERD necessitating further
exploration on this background.
IJTSRD48032
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@ IJTSRD | Unique Paper ID – IJTSRD48032 | Volume – 6 | Issue – 1 | Nov-Dec 2021 Page 1328
AIMS & OBJECTIVES
1. To study the role of homoeopathic medicines,
selected on the basis of Homoeopathic Principles
in the cases of GERD.
2. To study the Miasmatic background of GERD.
3. To study the outcome of Homoeopathic treatment
in GERD.
4. To study intensity and recurrence of sufferings
after administration of Homoeopathic medicines.
MATERIALS AND METHODOLOGY
1. Study setting:
Project site: Ahmedabad homoeopathic medical
college and Sainath hospital.
Duration of study: 12 months.
2. Selection of sample:
Number of cases: 50 patients with complaints of
Gastro-oesophageal reflux disorder will be
considered.
3. Inclusion criteria:
Both sexes and age group of 10 to 69 will be
considered.
All socio and economical classes will be
considered.
4. Exclusion Criteria:
Cases with irreversible pathological changes like
Barrate’s oesophagus, Adenocarcinoma of
oesophagus and pure surgical cases are excluded.
Cases with irregular follow ups.
5. Study Design:
Experimental.
6. Assessment Criteria:
Marked/Significant improvement- Complete
removal of subjective and objective symptoms
accept occasional or no recurrence of complains.
Moderate improvement- Subsidence of subjective
and objective symptoms with decrease in
duration, intensity and frequency of complains.
No improvement- No response after considerable
period of treatment.
7. Conclusion:
It is based on outcome of result on bases of
material and methods.
OBSERAVATION AND RESULT:
This section contains the description of data collected
from 50 cases, who attended the OPD of Sainath
Hospital, collaborated with Ahmedabad
Homoeopathic Medical College, Bopal, Ahmedabad.
The cases were selected on the basis of Random
sampling method. The data collected from these
patients were subjected to statistical analysis.
Descriptive, inferential statistics are used in analysis
and interpretation of study. The observations made
and results of this analysis are presented in the form
of tables, diagrams and charts.
DEMOGRAPHY: -
TABLE NO. 1 DISTRIBUITION OF PATIENT ACCORDING TO SEX
SEX NO. OF PATIENTS NO. OF PATIENTS IN PERCENTAGE
MALE 17 34%
FEMALE 33 66%
TOTAL 50 100%
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OBSERVATION FROM TABLE 1
Out of 50 cases selected for study, As shown in table 1, 33 of patients (66%) were females and 17 of patients
(34%) were male. This suggest occurrence of Gastro-oesophageal reflux disorder is predominant in Females than
compared to Male.
TABLE 2 DISTRIBUTION OF PATIENTS ACCORDING TO THEIR AGE
Age Group of Patient
(In Year)
Number of Patients NUMBER OF PATIENT
IN Percentage (%)
Male Female Total
10-19 0 1 1 2
20-29 1 8 9 18
30-39 14 10 24 48
40-49 3 4 7 14
50-59 2 2 4 8
60-69 2 3 5 10
DISTRIBUTION OF PATIENTS ACCORDING TO THEIR AGE
Observation from Table-2:
As shown in Table 2, maximum incidence of Gastro-oesophageal reflux disorder is seen in age group of 30 to 40
years, which is 48% (24 patients). After that, age groups of 20 to 29 and 40 to 49 years with the incidence of
18% and 14% (18 and 14 patients), age group of 60 to 69 years with the incidence of 10% (5 patients) and,
minimum incidence is seen in age group of 10 to 19 years which is 2% (1 patients).
TABLE 3 DISTRIBUTION OF CASES ACCORDING TO MIASM
MIASM (Gastro-oesophageal
reflux disorder)
NUMBER OF
PATIENTS
NUMBER OF PATIENTS
IN PERCENTAGE (%)
Psora 25 50
Sycotic 19 38
Syphilitic 3 6
Psora+ Syphilis (Tubercular) 2 4
Sycotic + Syphilitic 1 2
TOTAL 50 100
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0%
10%
20%
30%
40%
50%
60%
Psora Sycotic Syphilitic Psora + Syphilitic Sycotic + Syphilitic
Miasm
Percentage
From Table-3:
As shown in table-3; maximum patients are having Psoric miasm in background, 50% (25 Patients), 38% of
patients are having Sycotic miasm in background. Remaining 6%, 4% and 2% of patients are having Syphilitic,
Psora + Syphilitic and Sycotic + Syphilitic in background.
TABLE 4 DISTRIBUTION ACCORDING TO MEDICINE PRISCRIBE TO PATIENT
Medicine No. of medicines
Nux Vomica 4
Bryonia 3
Natrum Mur 3
Carbo veg 2
Iris Ver 2
Acid Sulph 2
Asafoetida 2
Chelidonium 2
Arsenicum Album 2
Sepia 2
Sulphur 2
Robinia 1
Gelsemium 1
Raphanus 1
Merc sol 1
Phosphorous 1
Mag Phos 1
Mag Mur 1
Borax 1
Alumina 1
Cimicifuga 1
Calcarea carb 1
Aethusa C 1
Aloe Soc 1
Natrum Phos 1
Argentum Nitricum 1
Rheum- 1
Picric Acid 1
Causticum 1
Graphitis 1
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Sangunaria 1
Cardus M. 1
Coccus cacti 1
Veretrum Alb 1
Natrum Sulph 1
Veretrum Viridi 1
0
0.5
1
1.5
2
2.5
3
3.5
4
4.5
No. of Medicine
Above table shows, Nux vomica is given in 4 cases out of 50. But this doesn’t indicate a group of medicines,
particularly indicated in this condition. This means that, though disease condition may remain same, the sick
individual will manifest the symptoms of as per their own individual pattern of reaction & their own mode of
living.
TABLE NO. 5 DISTRIBUTION OF PATIENTS ACCORDING TO FREQUENCY OF SYMPTOMS
PER WEEK
Frequency per week No. of Patients No. of patient in percentage (%)
3 8 16
4 12 24
5 8 16
6 7 14
7 15 30
Total 50 100
0
2
4
6
8
10
12
14
16
3 4 5 6 7
Frequency per week
total no. of patient
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As per table no. 5, 30% of patients manifest Symptoms of GERD every day in week.
TABLE NO. 6 RESPONSE OF PATIENTS TO TREATMENT
RESPONSE TO TREATMENT NUMBER OF PATIENT PERCENTAGE (100%)
Significant Improvement 38 76
Moderate Improvement 9 18
No improvement 3 6
Total 50 100
As per table no. 6,
76% of the patients showed significant improvement after treatment. 18% showed moderate improvement. Here,
moderate improvement is considered in those cases, where Anti miasmatic medicines had to administered during
treatment, to bring out Improvement in condition. 6% showed no improvement with treatment.
DISCUSSION
The study undertaken here is one of the most
common condition found in our day-to-day life. This
condition is not the one which may prove to be life
threatening, but is the one which causes lot of
discomfort as the array of symptoms which it
produces, mainly like Heartburn and Regurgitation.
GERD is the most common condition of upper GIT,
involving lower oesophageal sphincter. GERD is one
of the chronic, common and relapsing condition.
Hence it is necessary to diagnose, cure the disease
and prevent the recurrence in order to improve quality
of life. About 66% of females between age of 10 to
69 year show significant Symptoms as compared to
34% of males in the same age group. It is also
detected in pregnant women. It may be present as
secondary manifestations to some illness or it may be
drug induced. In other mode of treatment, they
concentrate more over controlling the acute attack for
management of disease rather than giving permanent
cure & considering the patient who is suffering. They
try to manage the disease by giving oral as well as
injectable Antacids, in which chance of recurrence is
much higher & sometimes due to recurrent
administrations of PPI, symptoms of Developing
Structural changes may remain unrecognize.
Homoeopathic mode of treatment is superior to other
modes of treatment since it treats the person as a
whole, not the diseased parts or organs. It is the man
who is sick and not his body and as a matter of fact he
needs to be treated.
It is here the concept of individualization comes into
practice, where the physical as well as the mental
characteristics of the individual is taken.
This includes, detailed case taking, in order to make
portrait of disease, which helps in person diagnosis,
disease diagnosis and management of case, both
specific as well as general.
We in Homoeopathy, believes in concept of
Individualization. We decide the potency as per
susceptibility of the patient. Susceptibilityis power of
organism to react against external stimuli. Higher the
susceptibility, High will be the potency.
Therefore, a study has been taken to evolve a suitable
homoeopathic approach in the effective management
of GERD.
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In this study maximum incidence of GERD was seen
in the age group of 30-39 years, which is 24 patients
(48%), in which 14 patients were male and 10
patients were female, out of 50 (100%). 9 (18%) were
in the age group of 20-29, in which 1 patient were
male and 8 patients were female. 7 (14%) were in the
age group of 40-49 years, in which 3 patients were
male and 4 patients were female. 5 (10%) were in the
age group of 60-69 years in which 2 patients were
male and 3 patients were female. And 4 (8%) were in
the age group of 50-59 years, in which 2 patients was
male and 2 patients was female. As per the literature,
Incidence of GERD is increasing with age, commonly
seen in female> male. This study is agreeing with
that.
As seen in the study 33 patients (66%) were female
and 17 patients (34%) were male.
As per the literature, GERD Affects the people
irrespective of sex. This study is agreed with this.
As per study, Nux vomica is given in 4 cases out of
50 cases & Bryonia, Natrum mur, Carbo veg were
given for 3 times. But this doesn’t indicate a group of
medicines, particularly indicated in this condition.
This means that, though disease condition may
remain same, the sick individual will manifest the
symptoms of as per their own individual pattern of
reaction & their own mode of living. Hence, in this
study, Selection of medicine has done on the basis of
individualization.
As per study, out of 50 cases: 38 patients (76%) were
markedly or significantly improved, 9 patients (18%)
were moderately improved, 3 patients (6%) were not
improved.
SUMMARY AND CONCLUSION
GERD is a common health problem which many
times remain undetected due to free and wide spread
use of PPIs & sometimes patient may diagnose the
complaint by themselves & they avoid to go to clinics
unless they cause discomfort.
But the GERD can be very well treated with
homeopathic remedies without any complications. It
commonly affects the quality of life of patient. 50
different cases have been taken, who are suffering
from GERD. (based on inclusion and exclusion
criteria) between the age of 10-69 years, from the
Sainath Hospital, collaborated with Ahmedabad
Homeopathic Medical college for the study. These
cases were followed regularly.
They were studied according to age, sex, according to
type of disease, according to remedy selection and
results.
Chief complains, Causation, Sensation, Location,
modalities & concomitants. Along with other
associated co-morbidities, constitution, past history,
family history, physical generals, and mental are
considered in order to select similimum. Laws of
homeopathy (law of similar, law of single, law
minimum dose and law of individualization) were
followed in all the cases.
Wherever possible majority of cases are studied with
laboratory investigations, which are CBC, Urine R/M,
SGPT, Creatinine, RBS. And in cases with chest pain
& Gabharaman, ECG has also taken in order to rule
out any cardiac cause.
Majority of cases which has studied were taken
primarily allopathic treatment. but due to repeated
attacks and increase severity, they selected
homeopathic mode of treatment.
Here, in each cases remedy was selected on the basis
of law of similarity. Individualization of the patient,
in order to reduce suffering & prevent relapses.
Patients are advised to take regular medicine and
follow the preventive measurement given.
After this study, I reach on following conclusion:
Out of 50 cases, Marked/Significant improvement
found in 38 patients (76%), Moderate
improvement found in 9 patients (18%), No
improvement seen in 3 patients (6%). This proves
that, when homeopathic medicine selected on the
basis Symptom similarity, (considering Mental
and Physical) it gives desirable results.
In my study I have found females are affected
more than males. Majority cases are found in the
age group of 30-39years (48%). Most of the
patients are found to having Classical symptoms
of GERD (Heartburn, Regurgitation) along with
Headache & Constipation.
Though there are so many specific, indicated
medicines for GERD, but in my study, I found
that no two cases are alike. Hence, medicine is
selected on the basis of symptom similarity and
individualization of patients. the recovery,
Significant improvement, Moderate improvement
and No improvement was 76:18:6.
Thus, positive result was obtained.
This shows that, no medicine can be a specific for all
the cases of GERD.
This work considering conscientious and diligent
observations made on 50 cases and its statistical
outcome concludes that homeopathic medicine if
chosen authentically on the basis of Symptom
similarity, can bring about the outstanding results,
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irrespective of severity of symptoms, gross local
pathological changes.
Secondly, a single remedy given with the
minimum dose shall bring about the steady but
sure and consistent result in the cases of GERD.
In some cases, where improvement stops,
Administration of Intercurrent medicines, will
help to bring about cure. In my study, I have Used
sulphur, Thuja, Medorrhinum etc as an
intercurrent medicines in cases of moderate
improvement.
As Upper GI Scopy was not carried out in all the
cases, the exact aetiology couldn’t be understood.
Therefore, the effectiveness of each these
homeopathic medicines in different conditions
could not be analysed.
RESULTS
The results obtained from this studyhas utilityin day-
to-day practice. I have found in study that few cases
didn’t response to the medicine selected, but the
result was positive.
In each case, similimum was given, based on
individualization. The present attempt of this study is
to evaluated the role of homeopathic medicines in
GERD, to reduce the sufferings, prevent recurrence.
GERD is one of the most common problem now a
days due to major life style errors in both men &
women, having maximum time visits to the hospital.
The demand of the time to improve clinical
applicability of homeopathic remedies. This is my
sincere endeavour to throw light on the subject and to
initiate more research work in this channel. Despite
the modern trend towards group thinking, group
practice, emergence of very recent concept of
universality and globalization, Individualisation is
still unique and continued to be as an important factor
as before towards sustained growth of mankind and
homeopathy. Homeopathy is principle concerned with
the law of SIMILARITY, so selection of medicine is
based on symptom similarity, no specification or
groupism were considered. Only law of similarity is
considered. I humbly submit this work to
Homeopathic fraternity for their scrutiny, approval,
guidance and application.
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Role of Homeopathy in Management of GERD

  • 1. International Journal of Trend in Scientific Research and Development (IJTSRD) Volume 6 Issue 1, November-December 2021 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470 @ IJTSRD | Unique Paper ID – IJTSRD48032 | Volume – 6 | Issue – 1 | Nov-Dec 2021 Page 1327 Role of Homeopathy in Management of GERD Dr. Nidhi Dave MD (Hom), Consultant Homoeopathic Physician, Sainath Hospital, Ahmedabad Attached to Ahmedabad Homoeopathic Medical College, Parul University ABSTRACT Gastroesophageal reflux disease (GERD) is a common disease of the gastrointestinal tract. GERD is defined as symptoms or mucosal damage as a result of abnormal reflux of gastric contents into the oesophagus or beyond. GER (Gastro-oesophageal reflux) is a normal physiologic process in which there will be retrograde movement of gastric contents from the stomach to the oesophagus. GER is not a disease. It occurs several times a day without mucosal damage or symptoms. GERD is caused by failure of anti-reflux barrier. GERD occurs when stomach contents move to the oesophagus effortlessly which cause the reflux symptoms like heartburn and regurgitation. It is a multifactorial process. KEYWORDS: Gastro-oesophageal reflux, Gastro-oesophageal reflux disorder, Homoeopathy, GERD, Homoeopathic management, Reflux oesophagitis How to cite this paper: Dr. Nidhi Dave "Role of Homeopathy in Management of GERD" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456- 6470, Volume-6 | Issue-1, December 2021, pp.1327-1336, URL: www.ijtsrd.com/papers/ijtsrd48032.pdf Copyright © 2021 by author (s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0) INTRODUCTION The term Gastroesophageal refers to the stomach and oesophagus. Reflux means to flow back or return. Therefore, gastroesophageal reflux is the return of the stomach's contents back up into the oesophagus. Gastroesophageal reflux disease (GERD) is a common disease of the gastrointestinal tract. GERD is defined as symptoms or mucosal damage as a result of abnormal reflux of gastric contents into the oesophagus or beyond. GER (Gastro-oesophageal reflux) is a normal physiologic process in which there will be retrograde movement of gastric contents from the stomach to the oesophagus. GER is not a disease. It occurs several times a day without mucosal damage or symptoms. GERD is caused by failure of anti-reflux barrier. GERD occurs when stomach contents move to the oesophagus effortlessly which cause the reflux symptoms like heartburn and regurgitation. It is a multifactorial process. GERD affects the quality of life. Using endoscopy, GERD can be classified into non erosive reflux disease and erosive esophagitis. According to Los Angeles classification erosive esophagitis is graded from A-D. It has a wide variety of clinical presentations ranging from gastrointestinal (common) to extra-gastrointestinal (uncommon) symptoms. Common gastrointestinal symptoms classical triad of symptoms is retrosternal burning pain (heartburn), epigastric pain (sometimes radiating through to the back) and regurgitation. Extra gastrointestinal symptoms are bronchial asthma, laryngitis, hoarseness of voice, chronic cough, sore throat and dental erosions. Diverse studies on various population and lifestyle background had been reported in previous literature, however the data were few from our part of the country. Henceforth, warranting more studies representing the facts from our province of the country. Furthermore, longstanding and untreated GERD leads to morbid complications such as oesophageal ulcer, Barrett’s oesophagus and oesophageal stricture. However, variable inference had been postulated regarding the association of clinical, lifestyle and endoscopic characteristics associated with complications of GERD necessitating further exploration on this background. IJTSRD48032
  • 2. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD48032 | Volume – 6 | Issue – 1 | Nov-Dec 2021 Page 1328 AIMS & OBJECTIVES 1. To study the role of homoeopathic medicines, selected on the basis of Homoeopathic Principles in the cases of GERD. 2. To study the Miasmatic background of GERD. 3. To study the outcome of Homoeopathic treatment in GERD. 4. To study intensity and recurrence of sufferings after administration of Homoeopathic medicines. MATERIALS AND METHODOLOGY 1. Study setting: Project site: Ahmedabad homoeopathic medical college and Sainath hospital. Duration of study: 12 months. 2. Selection of sample: Number of cases: 50 patients with complaints of Gastro-oesophageal reflux disorder will be considered. 3. Inclusion criteria: Both sexes and age group of 10 to 69 will be considered. All socio and economical classes will be considered. 4. Exclusion Criteria: Cases with irreversible pathological changes like Barrate’s oesophagus, Adenocarcinoma of oesophagus and pure surgical cases are excluded. Cases with irregular follow ups. 5. Study Design: Experimental. 6. Assessment Criteria: Marked/Significant improvement- Complete removal of subjective and objective symptoms accept occasional or no recurrence of complains. Moderate improvement- Subsidence of subjective and objective symptoms with decrease in duration, intensity and frequency of complains. No improvement- No response after considerable period of treatment. 7. Conclusion: It is based on outcome of result on bases of material and methods. OBSERAVATION AND RESULT: This section contains the description of data collected from 50 cases, who attended the OPD of Sainath Hospital, collaborated with Ahmedabad Homoeopathic Medical College, Bopal, Ahmedabad. The cases were selected on the basis of Random sampling method. The data collected from these patients were subjected to statistical analysis. Descriptive, inferential statistics are used in analysis and interpretation of study. The observations made and results of this analysis are presented in the form of tables, diagrams and charts. DEMOGRAPHY: - TABLE NO. 1 DISTRIBUITION OF PATIENT ACCORDING TO SEX SEX NO. OF PATIENTS NO. OF PATIENTS IN PERCENTAGE MALE 17 34% FEMALE 33 66% TOTAL 50 100%
  • 3. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD48032 | Volume – 6 | Issue – 1 | Nov-Dec 2021 Page 1329 OBSERVATION FROM TABLE 1 Out of 50 cases selected for study, As shown in table 1, 33 of patients (66%) were females and 17 of patients (34%) were male. This suggest occurrence of Gastro-oesophageal reflux disorder is predominant in Females than compared to Male. TABLE 2 DISTRIBUTION OF PATIENTS ACCORDING TO THEIR AGE Age Group of Patient (In Year) Number of Patients NUMBER OF PATIENT IN Percentage (%) Male Female Total 10-19 0 1 1 2 20-29 1 8 9 18 30-39 14 10 24 48 40-49 3 4 7 14 50-59 2 2 4 8 60-69 2 3 5 10 DISTRIBUTION OF PATIENTS ACCORDING TO THEIR AGE Observation from Table-2: As shown in Table 2, maximum incidence of Gastro-oesophageal reflux disorder is seen in age group of 30 to 40 years, which is 48% (24 patients). After that, age groups of 20 to 29 and 40 to 49 years with the incidence of 18% and 14% (18 and 14 patients), age group of 60 to 69 years with the incidence of 10% (5 patients) and, minimum incidence is seen in age group of 10 to 19 years which is 2% (1 patients). TABLE 3 DISTRIBUTION OF CASES ACCORDING TO MIASM MIASM (Gastro-oesophageal reflux disorder) NUMBER OF PATIENTS NUMBER OF PATIENTS IN PERCENTAGE (%) Psora 25 50 Sycotic 19 38 Syphilitic 3 6 Psora+ Syphilis (Tubercular) 2 4 Sycotic + Syphilitic 1 2 TOTAL 50 100
  • 4. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD48032 | Volume – 6 | Issue – 1 | Nov-Dec 2021 Page 1330 0% 10% 20% 30% 40% 50% 60% Psora Sycotic Syphilitic Psora + Syphilitic Sycotic + Syphilitic Miasm Percentage From Table-3: As shown in table-3; maximum patients are having Psoric miasm in background, 50% (25 Patients), 38% of patients are having Sycotic miasm in background. Remaining 6%, 4% and 2% of patients are having Syphilitic, Psora + Syphilitic and Sycotic + Syphilitic in background. TABLE 4 DISTRIBUTION ACCORDING TO MEDICINE PRISCRIBE TO PATIENT Medicine No. of medicines Nux Vomica 4 Bryonia 3 Natrum Mur 3 Carbo veg 2 Iris Ver 2 Acid Sulph 2 Asafoetida 2 Chelidonium 2 Arsenicum Album 2 Sepia 2 Sulphur 2 Robinia 1 Gelsemium 1 Raphanus 1 Merc sol 1 Phosphorous 1 Mag Phos 1 Mag Mur 1 Borax 1 Alumina 1 Cimicifuga 1 Calcarea carb 1 Aethusa C 1 Aloe Soc 1 Natrum Phos 1 Argentum Nitricum 1 Rheum- 1 Picric Acid 1 Causticum 1 Graphitis 1
  • 5. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD48032 | Volume – 6 | Issue – 1 | Nov-Dec 2021 Page 1331 Sangunaria 1 Cardus M. 1 Coccus cacti 1 Veretrum Alb 1 Natrum Sulph 1 Veretrum Viridi 1 0 0.5 1 1.5 2 2.5 3 3.5 4 4.5 No. of Medicine Above table shows, Nux vomica is given in 4 cases out of 50. But this doesn’t indicate a group of medicines, particularly indicated in this condition. This means that, though disease condition may remain same, the sick individual will manifest the symptoms of as per their own individual pattern of reaction & their own mode of living. TABLE NO. 5 DISTRIBUTION OF PATIENTS ACCORDING TO FREQUENCY OF SYMPTOMS PER WEEK Frequency per week No. of Patients No. of patient in percentage (%) 3 8 16 4 12 24 5 8 16 6 7 14 7 15 30 Total 50 100 0 2 4 6 8 10 12 14 16 3 4 5 6 7 Frequency per week total no. of patient
  • 6. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD48032 | Volume – 6 | Issue – 1 | Nov-Dec 2021 Page 1332 As per table no. 5, 30% of patients manifest Symptoms of GERD every day in week. TABLE NO. 6 RESPONSE OF PATIENTS TO TREATMENT RESPONSE TO TREATMENT NUMBER OF PATIENT PERCENTAGE (100%) Significant Improvement 38 76 Moderate Improvement 9 18 No improvement 3 6 Total 50 100 As per table no. 6, 76% of the patients showed significant improvement after treatment. 18% showed moderate improvement. Here, moderate improvement is considered in those cases, where Anti miasmatic medicines had to administered during treatment, to bring out Improvement in condition. 6% showed no improvement with treatment. DISCUSSION The study undertaken here is one of the most common condition found in our day-to-day life. This condition is not the one which may prove to be life threatening, but is the one which causes lot of discomfort as the array of symptoms which it produces, mainly like Heartburn and Regurgitation. GERD is the most common condition of upper GIT, involving lower oesophageal sphincter. GERD is one of the chronic, common and relapsing condition. Hence it is necessary to diagnose, cure the disease and prevent the recurrence in order to improve quality of life. About 66% of females between age of 10 to 69 year show significant Symptoms as compared to 34% of males in the same age group. It is also detected in pregnant women. It may be present as secondary manifestations to some illness or it may be drug induced. In other mode of treatment, they concentrate more over controlling the acute attack for management of disease rather than giving permanent cure & considering the patient who is suffering. They try to manage the disease by giving oral as well as injectable Antacids, in which chance of recurrence is much higher & sometimes due to recurrent administrations of PPI, symptoms of Developing Structural changes may remain unrecognize. Homoeopathic mode of treatment is superior to other modes of treatment since it treats the person as a whole, not the diseased parts or organs. It is the man who is sick and not his body and as a matter of fact he needs to be treated. It is here the concept of individualization comes into practice, where the physical as well as the mental characteristics of the individual is taken. This includes, detailed case taking, in order to make portrait of disease, which helps in person diagnosis, disease diagnosis and management of case, both specific as well as general. We in Homoeopathy, believes in concept of Individualization. We decide the potency as per susceptibility of the patient. Susceptibilityis power of organism to react against external stimuli. Higher the susceptibility, High will be the potency. Therefore, a study has been taken to evolve a suitable homoeopathic approach in the effective management of GERD.
  • 7. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD48032 | Volume – 6 | Issue – 1 | Nov-Dec 2021 Page 1333 In this study maximum incidence of GERD was seen in the age group of 30-39 years, which is 24 patients (48%), in which 14 patients were male and 10 patients were female, out of 50 (100%). 9 (18%) were in the age group of 20-29, in which 1 patient were male and 8 patients were female. 7 (14%) were in the age group of 40-49 years, in which 3 patients were male and 4 patients were female. 5 (10%) were in the age group of 60-69 years in which 2 patients were male and 3 patients were female. And 4 (8%) were in the age group of 50-59 years, in which 2 patients was male and 2 patients was female. As per the literature, Incidence of GERD is increasing with age, commonly seen in female> male. This study is agreeing with that. As seen in the study 33 patients (66%) were female and 17 patients (34%) were male. As per the literature, GERD Affects the people irrespective of sex. This study is agreed with this. As per study, Nux vomica is given in 4 cases out of 50 cases & Bryonia, Natrum mur, Carbo veg were given for 3 times. But this doesn’t indicate a group of medicines, particularly indicated in this condition. This means that, though disease condition may remain same, the sick individual will manifest the symptoms of as per their own individual pattern of reaction & their own mode of living. Hence, in this study, Selection of medicine has done on the basis of individualization. As per study, out of 50 cases: 38 patients (76%) were markedly or significantly improved, 9 patients (18%) were moderately improved, 3 patients (6%) were not improved. SUMMARY AND CONCLUSION GERD is a common health problem which many times remain undetected due to free and wide spread use of PPIs & sometimes patient may diagnose the complaint by themselves & they avoid to go to clinics unless they cause discomfort. But the GERD can be very well treated with homeopathic remedies without any complications. It commonly affects the quality of life of patient. 50 different cases have been taken, who are suffering from GERD. (based on inclusion and exclusion criteria) between the age of 10-69 years, from the Sainath Hospital, collaborated with Ahmedabad Homeopathic Medical college for the study. These cases were followed regularly. They were studied according to age, sex, according to type of disease, according to remedy selection and results. Chief complains, Causation, Sensation, Location, modalities & concomitants. Along with other associated co-morbidities, constitution, past history, family history, physical generals, and mental are considered in order to select similimum. Laws of homeopathy (law of similar, law of single, law minimum dose and law of individualization) were followed in all the cases. Wherever possible majority of cases are studied with laboratory investigations, which are CBC, Urine R/M, SGPT, Creatinine, RBS. And in cases with chest pain & Gabharaman, ECG has also taken in order to rule out any cardiac cause. Majority of cases which has studied were taken primarily allopathic treatment. but due to repeated attacks and increase severity, they selected homeopathic mode of treatment. Here, in each cases remedy was selected on the basis of law of similarity. Individualization of the patient, in order to reduce suffering & prevent relapses. Patients are advised to take regular medicine and follow the preventive measurement given. After this study, I reach on following conclusion: Out of 50 cases, Marked/Significant improvement found in 38 patients (76%), Moderate improvement found in 9 patients (18%), No improvement seen in 3 patients (6%). This proves that, when homeopathic medicine selected on the basis Symptom similarity, (considering Mental and Physical) it gives desirable results. In my study I have found females are affected more than males. Majority cases are found in the age group of 30-39years (48%). Most of the patients are found to having Classical symptoms of GERD (Heartburn, Regurgitation) along with Headache & Constipation. Though there are so many specific, indicated medicines for GERD, but in my study, I found that no two cases are alike. Hence, medicine is selected on the basis of symptom similarity and individualization of patients. the recovery, Significant improvement, Moderate improvement and No improvement was 76:18:6. Thus, positive result was obtained. This shows that, no medicine can be a specific for all the cases of GERD. This work considering conscientious and diligent observations made on 50 cases and its statistical outcome concludes that homeopathic medicine if chosen authentically on the basis of Symptom similarity, can bring about the outstanding results,
  • 8. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD48032 | Volume – 6 | Issue – 1 | Nov-Dec 2021 Page 1334 irrespective of severity of symptoms, gross local pathological changes. Secondly, a single remedy given with the minimum dose shall bring about the steady but sure and consistent result in the cases of GERD. In some cases, where improvement stops, Administration of Intercurrent medicines, will help to bring about cure. In my study, I have Used sulphur, Thuja, Medorrhinum etc as an intercurrent medicines in cases of moderate improvement. As Upper GI Scopy was not carried out in all the cases, the exact aetiology couldn’t be understood. Therefore, the effectiveness of each these homeopathic medicines in different conditions could not be analysed. RESULTS The results obtained from this studyhas utilityin day- to-day practice. I have found in study that few cases didn’t response to the medicine selected, but the result was positive. In each case, similimum was given, based on individualization. The present attempt of this study is to evaluated the role of homeopathic medicines in GERD, to reduce the sufferings, prevent recurrence. GERD is one of the most common problem now a days due to major life style errors in both men & women, having maximum time visits to the hospital. The demand of the time to improve clinical applicability of homeopathic remedies. This is my sincere endeavour to throw light on the subject and to initiate more research work in this channel. Despite the modern trend towards group thinking, group practice, emergence of very recent concept of universality and globalization, Individualisation is still unique and continued to be as an important factor as before towards sustained growth of mankind and homeopathy. Homeopathy is principle concerned with the law of SIMILARITY, so selection of medicine is based on symptom similarity, no specification or groupism were considered. Only law of similarity is considered. I humbly submit this work to Homeopathic fraternity for their scrutiny, approval, guidance and application. REFERENCES [1] Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J. Preface Harrison's Manual of Medicine. Asia Book Registry. 2019 Aug 28. [2] Sitaraman SV, Friedman LS, editors. Essentials of gastroenterology. Wiley-Blackwell; 2012 Apr 30. [3] Tsai HH. Harrison's Gastroenterology and Hepatology. [4] Williams NS, O'Connell PR, McCaskie A, editors. Bailey & Love's short practice of surgery. CRC press; 2018 Apr 27. [5] Hahnemann S. Organon of medicine. B. Jain publishers; 2002. [6] Hahnemann S. The chronic diseases. Boericke & Tafel; 1904. [7] Campbell A. Principles and Practice of Homoeopathy, Vol. 1. By ML Dhawale. Karnatak Publishing House, Bombay. No price quoted. 638 pp. [8] Kent JT. Repertory of the homoeopathic materia medica. B. Jain Publishers; 1992. [9] Allen TF. Boenninghausen's Therapeutic Pocket Book. B. Jain Publishers; 2003. [10] Desai BD. Boger-Boenninghausen's Repertory. [11] Inderbir Singh, Pal GP. Text book of Human Embryology. Eight editions. Anatomy of the stomach:152-3. [12] Boericke W. Homeopathic Materia Medica. New York: Kessinger Publishing; 2004. [13] Stomach & epigastrium, epigastrium, Concomitant- Chest pains [14] Kang JY. Systematic review: geographical and ethnic differences in gastro-oesophageal reflux disease. Aliment Pharmocol Ther. 2004;20:705–717 [15] Sandier RS, Everhart JE, Donowitz M, et al. The burden of selected digestive diseases in the United States. Gastroenterology 2002 May; 122(5): 1500–11 [16] El-Serag HB, Sweet S, Winchester CC, Dent J. Update on the epidemiology of gastro- oesophageal reflux disease: a systematic review. Gut. 2014;63(6):871–80. doi: 10.1136/gutjnl-2012-304269. [17] Shobna J, Bhatia & D. Nageshwar Reddy et al. Epidemiology and symptom profile of gastroesophageal reflux in the Indian population: Report of the Indian Society of Gastroenterology Task Force. Indian J Gastroenterol (May–June 2011) 30(3):118–127 [18] Hai-Yun Wang, Kondarapassery Balakumaran Leena, et al. Prevalence of gastro-esophageal reflux disease and its risk factors in a communitybased population in southern India. BMC Gastroenterol. 2016; Mar 15, 16: 36.
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