if both the CEO and CIO were appointed what would be the difference between their roles Solution > CEO is Chief Executive Officer who takes care of the overall performance of the company >>CIO is Chief Information Officer who is responsible for enterprise\'s information technology and IT systems required for functioning of the organization and successful implementation of the company strategies >> A CEO is responsible for all the departments in the organization. A CIO is responsible only for IT department. Mostly CIOs report to CEOs in the organization..