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JOEL G. SORIA, PT, MD
Chapter 7 - The Muscular System
• Body Movement
• Maintenance of Posture
• Respiration
• Production of Body Heat
• Communication
• Constriction of Organs and Blood
Vessels
• Heart Beat
Functions
• CONTRACTILITY: ability of skeletal muscle to
shorten with force.
• EXCITABILITY: capacity of skeletal muscle to
respond to a stimulus.
• EXTENSIBILITY: skeletal muscle can be stretched
to their normal resting length and beyond to a
limited degree.
• ELASTICITY: ability of skeletal muscle muscles to
recoil to their original resting length after they
have been stretched.
Functional Characteristics
Sarcomere
Sarcoplasmic
Reticulum
Transverse Tubule
Capillaries
Nuclei
Bone
Tendon
Skeletal muscle
Epimysium
(fascia)
Fasciculi
Endomysium
Muscle fiber
Mitochondr
Myofibrils
Actin
Myosin
Sarcolema
Sarcomere – Basic structural and functional unit of
skeletal muscle.
– Each sarcomere extends from one Z-disk to
another Z-disk
Z-Disk – a network of protein fibers forming an
attachment site for actin myofilaments
Sarcomere – Basic structural and functional unit of
skeletal muscle.
– Each sarcomere extends from one Z-disk to
another Z-disk
Z-Disk – a network of protein fibers forming an
attachment site for actin myofilaments
Actin Myosin
• Troponin – attached at a specific interval along
the actin and provide calcium binding sites on the
actin myofilament
• Tropomyosin – located along the groove between
the twisted strands of actin myofilament.
Actin
Myosin
How does Skeletal Muscle Contracts?
1st	the	Central	
Nervous	System	
gives	the	order	for	
muscle	contraction
The	order	(to	contract)	
reaches	the	Muscle	thru	the		
Neuro-Muscular	Junction
Neuro-muscular Junction
• Charge Difference
– Higher concentration of Potassium (K+)
inside the cell membrane.
– Potassium is more permeable than other ions
• Action Potential – Rapid depolarization and
repolarization of the cell membrane
IN
- - - -
-
-
K	
Potassium
OUT
+ + + + +
+
Na	
Sodium
Membranepotential
Cell Membrane
Membranepotential
1.Action potential arriving at
the presynaptic terminal
causes synaptic vesicles to
move and to bind with the
cell membrane
2.Synaptic vesicles release
acetylcholine (Ach) into the
synaptic cleft by exocytosis
3.Acetylcholine diffuses
across the synaptic cleft
4.Acetylcholine binds to
Acetylcholine receptor sites
on Na+ channels in
postsynaptic (muscle) cell
membrane
5.Combination of
Acetylcholine with its
receptor site opens Na+
channels and causes and
increase in the permeability
of the muscle cell membrane
ACh binds to receptors
in the sarcolema band
spreads in all direction
Sends electrical
impulse to the t-tubules
Releases Calcium
Repolarization
Depolarization
• Force of contraction:
• Summation – Increase the force of the
contraction
• Recruitment – Increase the number of muscle
fibers contracting
• Tetanus – Sustained contraction
• Rigor mortis – Muscles become rigid
– Types of muscle contraction
– Isometric contraction – equal distance
– Isotonic contraction – equal tension
– Concentric contraction
– Eccentric contraction
– Muscle tone – Refers to the constant tension
produced by the muscle over long periods of
time
• Agonist – muscle that accomplishes a
certain movement.
• Antagonist – muscle acting to oppose the
agonist.
• Synergist – members of the same group
acting to produce a movement
• Prime movers
• Fixators

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Chapter 7 muscular

  • 1. JOEL G. SORIA, PT, MD Chapter 7 - The Muscular System
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  • 3. • Body Movement • Maintenance of Posture • Respiration • Production of Body Heat • Communication • Constriction of Organs and Blood Vessels • Heart Beat Functions
  • 4. • CONTRACTILITY: ability of skeletal muscle to shorten with force. • EXCITABILITY: capacity of skeletal muscle to respond to a stimulus. • EXTENSIBILITY: skeletal muscle can be stretched to their normal resting length and beyond to a limited degree. • ELASTICITY: ability of skeletal muscle muscles to recoil to their original resting length after they have been stretched. Functional Characteristics
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  • 7. Sarcomere – Basic structural and functional unit of skeletal muscle. – Each sarcomere extends from one Z-disk to another Z-disk Z-Disk – a network of protein fibers forming an attachment site for actin myofilaments
  • 8. Sarcomere – Basic structural and functional unit of skeletal muscle. – Each sarcomere extends from one Z-disk to another Z-disk Z-Disk – a network of protein fibers forming an attachment site for actin myofilaments
  • 10. • Troponin – attached at a specific interval along the actin and provide calcium binding sites on the actin myofilament • Tropomyosin – located along the groove between the twisted strands of actin myofilament. Actin
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  • 15. How does Skeletal Muscle Contracts? 1st the Central Nervous System gives the order for muscle contraction The order (to contract) reaches the Muscle thru the Neuro-Muscular Junction
  • 17. • Charge Difference – Higher concentration of Potassium (K+) inside the cell membrane. – Potassium is more permeable than other ions • Action Potential – Rapid depolarization and repolarization of the cell membrane IN - - - - - - K Potassium OUT + + + + + + Na Sodium Membranepotential Cell Membrane
  • 19. 1.Action potential arriving at the presynaptic terminal causes synaptic vesicles to move and to bind with the cell membrane 2.Synaptic vesicles release acetylcholine (Ach) into the synaptic cleft by exocytosis 3.Acetylcholine diffuses across the synaptic cleft 4.Acetylcholine binds to Acetylcholine receptor sites on Na+ channels in postsynaptic (muscle) cell membrane 5.Combination of Acetylcholine with its receptor site opens Na+ channels and causes and increase in the permeability of the muscle cell membrane
  • 20. ACh binds to receptors in the sarcolema band spreads in all direction Sends electrical impulse to the t-tubules Releases Calcium
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  • 25. • Force of contraction: • Summation – Increase the force of the contraction • Recruitment – Increase the number of muscle fibers contracting • Tetanus – Sustained contraction • Rigor mortis – Muscles become rigid
  • 26. – Types of muscle contraction – Isometric contraction – equal distance – Isotonic contraction – equal tension – Concentric contraction – Eccentric contraction – Muscle tone – Refers to the constant tension produced by the muscle over long periods of time
  • 27. • Agonist – muscle that accomplishes a certain movement. • Antagonist – muscle acting to oppose the agonist. • Synergist – members of the same group acting to produce a movement • Prime movers • Fixators