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Chapter 5
Integumentary System
Joel G. Soria, MD
Integumentary
What does integument mean?
ā€¢ covering
Components:
ā€¢ skin
ā€¢ hair
ā€¢ nails
ā€¢ glands
Skin
HypodermisDermisEpidermis
Functions
1. Protection:
water loss, microbes, UV light
2. Sensation:
hot, cold, pain, pressure
3. Temperature regulation:
helps maintain homeostasis
4. Excretion:
removes waste
5. Vitamin D production:
UV light stimulates production
Skin facts
ā€¢ Weighs 9 lbs.
ā€¢ Used to determine body fat
ā€¢ 2 main regions: epidermis and dermis
Epidermis
1st major skin region (outside)
Composed of stratified squamous
epithelium
Keratinization:
ā€¢ process ion which new cells (with
keratin) push old cells to surface
Strata of Epidermis
ā€¢ Stratum corneum:
- outermost layer of epidermis
- 20-30 layers of dead squamous cells filled with keratin
- accounts for 75% of epidermal thickness
- dandruff is this layer flaking off scalp
ā€¢ Callus:
forms when stratum corneum has frequent friction
ā€¢ Stratum basale:
- deepest layer of epidermis
- single layer of cells
- firmly attached to dermis
Dermis
2nd major skin region
Dense connective tissue
Contains collagen and elastic fibers
Contains fibroblasts, nerve endings, smooth muscle,
glands, blood vessels, and hair follicles
Cleavage lines:
ā€¢ area where skin is most
resistant to stretching
ā€¢ due to orientation of
collagen fibers
ā€¢ important in scarring
Layers of the Dermis
ā€¢ Papillary layer:
- thin connective tissue layer that
contains blood vessels
- Dermal papillae:
- projections that extend up into
epidermis
- remove waste and help regulate
body temp.
- ridged on hands and feet
(fingerprints)
- pattern is genetically determined
ā€¢ Reticular layer:
deepest layer of dermis
accounts for 80% of dermis
Hypodermis
Below dermis
Foundation of skin
Attaches skin to underlying muscle and bone
Contains loose and adipose tissue
Contains Ā½ I'm 20-23%, males 13-25%
Skin color and variations
ā€¢ Determined by:
- pigments
- genetics
- blood circulation
- thickness of stratum corneum
ā€¢ Melanocytes of darker skinned people produce more
and darker melanin than fairer skinned people
ā€¢ All races have same number of melanocytes
Skin Pigments
ā€¢ Melanin:
- produced by melanocytes
- ranges from yellow to reddish-brown to black
- responsible for hair and eye color
- provides protection against UV light
- amt. produced determined by genetics, UV light, hormones
- freckles are accumulation of melanin
- albinism is absence of melanin
ā€¢ Carotene:
- yellow-orange pigment found in plants
- accumulates in stratum corneum
ā€¢ Hemoglobin:
- gives pinkish-red color
- found in red blood cells
Tanning and Sunburn
ā€¢ Exposure to UV light stimulates melanocytes to increase
production of melanin
ā€¢ Melanin builds up to help protect skin against UV radiation
(tan)
ā€¢ A sunburn is the skin reacting to UV exposure
ā€¢ UV light causes elastic fibers to clump and become leathery
ā€¢ UV light can alter DNA in cells causing them to mutate
(cancer)
Skin Color and Disease
ā€¢ Redness:
fever, hypertension, inflammation, allergies
ā€¢ Pallor:
anemia or low blood pressure
ā€¢ Jaundice:
liver disorder (yellow)
ā€¢ Bronzing:
Addisonā€™s disease (kidney disease)
ā€¢ Bruising:
broken blood vessels
Hair Components
ā€¢ Hair/shaft:
flexible strands of keratinized cells
ā€¢ Root:
below skin (scalp)
ā€¢ Hair Bulb:
- base of root
- where hair is produced
ā€¢ Hair Follicle:
- group of cells that surround root and bulb
- gives hair different shapes
How is hair produced
ā€¢ Hair is produced in hair bulb
ā€¢ Hair bulb rests on blood vessels
to supply it with nutrients
ā€¢ Hair grows longer as cells are
added to base of hair bulb
Hair Facts
ā€¢ Testosterone and good nutrition promote hair growth
ā€¢ Growth occurs in cycles: active and resting
ā€¢ Scalp hair grows for 3 years and rests for 1 year
ā€¢ Eyelashes grow for 30 days and rest for 105 days
ā€¢ We lose about 90 scalp hairs/day
ā€¢ Grey hair is the loss or fading of melanin
ā€¢ Male pattern baldness is from the loss of the hair follicle
Hair muscles
ā€¢ Arrector Pili:
- smooth muscle that surrounds
each hair follicle
- contracts and hair stands on
end (goose bumps)
Glands
ā€¢ Sebaceous glands:
- connected to hair follicle
- sebum: oily substance that
lubricates hair and
skin to prevent drying
ā€¢ Eccrine sweat glands:
- all over body and open into
sweat pores
- water and salt secretions
ā€¢ Apocrine sweat glands:
- open into hair follicle
- only in armpits and genitalia
- thick, rich secretions
- become active during
puberty and cause body odor
Eccrine
sweat gland
Sebaceous gland
Arrector pili
(smooth muscle)
Duct of eccrine
sweat gland
Sweat pores
Apocrine
sweat gland
Hair bulb
Hair follicle
Duct of
apocrine
sweat gland
Vitamin D production
1. UV light causes skin to produce a precursor
molecule of vitamin D
2. Precursor is carried by blood to liver where it is modified
3. Next to kidneys where it is modified again to form active
vitamin D
ā€¢ Vitamin D can also be ingested through fish oils, fortified
milk, eggs, and butter.
ā€¢ Vitamin D stimulates intestine to absorb calcium and
phosphate (bone growth and muscle function)
Temperature regulation
ā€¢ Body temp. should be 98.6oC
ā€¢ Rate of chemical reactions
(metabolism) is altered by
changes in temp.
ā€¢ To cool body:
blood vessels in dermis dilate
and heat is transferred from deep
in tissues to skin and sweat is
produced
ā€¢ Too heat body:
blood vessels constrict to reduce
blood flow to skin and heat is
retained
Classiļ¬cation of Burn
ā€¢ 1st degree:
- damages only epidermis
- redness, slight swelling, pain
- heals within 2-3 days
(usually no scar)
- includes sunburns or
exposure to cold
Full-
thickness
Third-
degree
Subcutaneous
tissue
Dermis
Epidermis
Second-
degree
Partial-
thickness
First-
degree
Classiļ¬cation of Burn
ā€¢ 2nd degree:
- damages epidermis and upper dermis
- redness, swelling, pain, blisters
- heals in 2 weeks with some scarring
Classiļ¬cation of Burn
ā€¢ 3rd degree:
- destroys epidermis and dermis
- burned areas are cherry red to
black
- nerve endings are destroyed
- skin graft might be necessary

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Chapter 5 integumentary

  • 2. Integumentary What does integument mean? ā€¢ covering Components: ā€¢ skin ā€¢ hair ā€¢ nails ā€¢ glands
  • 4. Functions 1. Protection: water loss, microbes, UV light 2. Sensation: hot, cold, pain, pressure 3. Temperature regulation: helps maintain homeostasis 4. Excretion: removes waste 5. Vitamin D production: UV light stimulates production
  • 5. Skin facts ā€¢ Weighs 9 lbs. ā€¢ Used to determine body fat ā€¢ 2 main regions: epidermis and dermis
  • 6. Epidermis 1st major skin region (outside) Composed of stratified squamous epithelium Keratinization: ā€¢ process ion which new cells (with keratin) push old cells to surface
  • 7. Strata of Epidermis ā€¢ Stratum corneum: - outermost layer of epidermis - 20-30 layers of dead squamous cells filled with keratin - accounts for 75% of epidermal thickness - dandruff is this layer flaking off scalp ā€¢ Callus: forms when stratum corneum has frequent friction ā€¢ Stratum basale: - deepest layer of epidermis - single layer of cells - firmly attached to dermis
  • 8. Dermis 2nd major skin region Dense connective tissue Contains collagen and elastic fibers Contains fibroblasts, nerve endings, smooth muscle, glands, blood vessels, and hair follicles
  • 9. Cleavage lines: ā€¢ area where skin is most resistant to stretching ā€¢ due to orientation of collagen fibers ā€¢ important in scarring
  • 10. Layers of the Dermis ā€¢ Papillary layer: - thin connective tissue layer that contains blood vessels - Dermal papillae: - projections that extend up into epidermis - remove waste and help regulate body temp. - ridged on hands and feet (fingerprints) - pattern is genetically determined ā€¢ Reticular layer: deepest layer of dermis accounts for 80% of dermis
  • 11. Hypodermis Below dermis Foundation of skin Attaches skin to underlying muscle and bone Contains loose and adipose tissue Contains Ā½ I'm 20-23%, males 13-25%
  • 12. Skin color and variations ā€¢ Determined by: - pigments - genetics - blood circulation - thickness of stratum corneum ā€¢ Melanocytes of darker skinned people produce more and darker melanin than fairer skinned people ā€¢ All races have same number of melanocytes
  • 13. Skin Pigments ā€¢ Melanin: - produced by melanocytes - ranges from yellow to reddish-brown to black - responsible for hair and eye color - provides protection against UV light - amt. produced determined by genetics, UV light, hormones - freckles are accumulation of melanin - albinism is absence of melanin ā€¢ Carotene: - yellow-orange pigment found in plants - accumulates in stratum corneum ā€¢ Hemoglobin: - gives pinkish-red color - found in red blood cells
  • 14.
  • 15. Tanning and Sunburn ā€¢ Exposure to UV light stimulates melanocytes to increase production of melanin ā€¢ Melanin builds up to help protect skin against UV radiation (tan) ā€¢ A sunburn is the skin reacting to UV exposure ā€¢ UV light causes elastic fibers to clump and become leathery ā€¢ UV light can alter DNA in cells causing them to mutate (cancer)
  • 16. Skin Color and Disease ā€¢ Redness: fever, hypertension, inflammation, allergies ā€¢ Pallor: anemia or low blood pressure ā€¢ Jaundice: liver disorder (yellow) ā€¢ Bronzing: Addisonā€™s disease (kidney disease) ā€¢ Bruising: broken blood vessels
  • 17. Hair Components ā€¢ Hair/shaft: flexible strands of keratinized cells ā€¢ Root: below skin (scalp) ā€¢ Hair Bulb: - base of root - where hair is produced ā€¢ Hair Follicle: - group of cells that surround root and bulb - gives hair different shapes
  • 18. How is hair produced ā€¢ Hair is produced in hair bulb ā€¢ Hair bulb rests on blood vessels to supply it with nutrients ā€¢ Hair grows longer as cells are added to base of hair bulb
  • 19. Hair Facts ā€¢ Testosterone and good nutrition promote hair growth ā€¢ Growth occurs in cycles: active and resting ā€¢ Scalp hair grows for 3 years and rests for 1 year ā€¢ Eyelashes grow for 30 days and rest for 105 days ā€¢ We lose about 90 scalp hairs/day ā€¢ Grey hair is the loss or fading of melanin ā€¢ Male pattern baldness is from the loss of the hair follicle
  • 20. Hair muscles ā€¢ Arrector Pili: - smooth muscle that surrounds each hair follicle - contracts and hair stands on end (goose bumps)
  • 21. Glands ā€¢ Sebaceous glands: - connected to hair follicle - sebum: oily substance that lubricates hair and skin to prevent drying ā€¢ Eccrine sweat glands: - all over body and open into sweat pores - water and salt secretions
  • 22. ā€¢ Apocrine sweat glands: - open into hair follicle - only in armpits and genitalia - thick, rich secretions - become active during puberty and cause body odor
  • 23. Eccrine sweat gland Sebaceous gland Arrector pili (smooth muscle) Duct of eccrine sweat gland Sweat pores Apocrine sweat gland Hair bulb Hair follicle Duct of apocrine sweat gland
  • 24. Vitamin D production 1. UV light causes skin to produce a precursor molecule of vitamin D 2. Precursor is carried by blood to liver where it is modified 3. Next to kidneys where it is modified again to form active vitamin D ā€¢ Vitamin D can also be ingested through fish oils, fortified milk, eggs, and butter. ā€¢ Vitamin D stimulates intestine to absorb calcium and phosphate (bone growth and muscle function)
  • 25. Temperature regulation ā€¢ Body temp. should be 98.6oC ā€¢ Rate of chemical reactions (metabolism) is altered by changes in temp. ā€¢ To cool body: blood vessels in dermis dilate and heat is transferred from deep in tissues to skin and sweat is produced ā€¢ Too heat body: blood vessels constrict to reduce blood flow to skin and heat is retained
  • 26. Classiļ¬cation of Burn ā€¢ 1st degree: - damages only epidermis - redness, slight swelling, pain - heals within 2-3 days (usually no scar) - includes sunburns or exposure to cold
  • 28. Classiļ¬cation of Burn ā€¢ 2nd degree: - damages epidermis and upper dermis - redness, swelling, pain, blisters - heals in 2 weeks with some scarring
  • 29. Classiļ¬cation of Burn ā€¢ 3rd degree: - destroys epidermis and dermis - burned areas are cherry red to black - nerve endings are destroyed - skin graft might be necessary