- The digestive system breaks down food into smaller molecules that can be absorbed and used to fuel body activities. It consists of a tubular gastrointestinal tract and accessory organs like the liver and pancreas. - The mouth, esophagus, and stomach are involved in initial digestion through chewing, swallowing, and stomach acid. The small intestine further breaks down food with enzymes from the pancreas and liver and absorbs nutrients. The large intestine absorbs water before waste is excreted.