7. … but how to measure?
Micro-scale
• Electron microscopy
• Axonal tracing??
Meso-scale
• Clarity
• Brainbows
• …
Macro-scale
• MRI
• CT
• PET
• SPECT
• …
Ex-vivo In-vivo
8. Important historical events
~ from my subjective perspective ~
1973
1975
1979 1986-1988
1985 1991
2005
X-Ray
CT imaging
invented
PET imaging
invented
MRI imaging
invented Birth of
cognitive
neuroscience
First diffusion
MRI images
published
fMRI imaging
began in
human
subjects
First
macroscale
connectome by
Hagmann &
Sporns
9. YOU know, what these people do is really
very clever. They put little spies into the
molecules and send radio signals to them,
and they have to radio back what they are
seeing.
- Niels Bohr
(Nobel prize in Physics)
14. The “Connectome”
In complete analogy to
the word “genome”. The
“-ome” emphasizes the
notion that the brain is a
large and unique
complex system:
a network made of
structural and functional
connections (edges)
linking specific neural
units (nodes).
18. We’re doing a really shitty job.
It’s not because we’re not trying;
it has to do with the complexity of
the problem
- Guy Rouleau, the director of McGill
University’s Montreal Neurological
Institute (MNI)
1.3 kg ping jelly
Consumes 20% of total energy produced in the body and takes 2% size total size of the body
100 billion neurons (15x more than total human population
75% of the total brain mass is comprised of water which regulates various functions in the brain.
We are living at the casp of a golden age in neuroscience. This is the infancy of a renessanse
TODO data dimension
Video
To do data information
The amount of acquired neuroimaging data reported from published articles in representative isues of the journal NeuroImage has doubled every 26 months and can expect to top 20GB of purely raw data on average per study in only a few years. Amassing, curating, storing, and sharing of such data from neuroimaging archives presents a growing big data challenge.
Open BCI project in NY which using kick started funding has produced 3D printed open source brain machine interface. You can now do neuroscience at home.
Open BCI project in NY which using kick started funding has produced 3D printed open source brain machine interface. You can now do neuroscience at home.