Risofos (Generic Risedronate Sodium Tablets)

Generic Risedronate Sodium Tablets
© Clearsky Pharmacy
Risofos (Generic Risedronate Sodium tablets) is
a bisphosphonate used for the treatment and
prevention of postmenopausal osteoporosis,
treatment to increase bone mass in men with
osteoporosis, treatment and prevention of
glucocorticoid-induced osteoporosis and
treatment of Paget’s disease.

Risofos Tablets
Risofos Tablets are manufactured by
Cipla Ltd., India.
(Website: www.cipla.com)

Risedronate Sodium Tablets – Brand Names
Risedronate Sodium Sodium tablets
are available as Actonel, Risofos,
Fossical and Gemfos .

Active Ingredient
The active ingredient contained in Risofos
tablets is Risedronate Sodium. Each tablet
contains either 35 mg, 75 mg or 150 mg of
Risedronate Sodium

Chemical Structure
The structure of Risedronate Sodium is
given below:

Uses of Risofos Tablets
Risofos tablets is used for the treatment and
prevention of osteoporosis in postmenopausal
women.
This medicine is used for treatment of
Osteoporosis in Men to increase bone mass in
men with osteoporosis.
This medicine is also used for the treatment and
prevention of glucocorticoid-induced
osteoporosis in men and women who are either
initiating or continuing systemic glucocorticoid
treatment (daily dosage of 7.5 mg prednisone or
higher or equivalent) for chronic diseases and
for treatment of Paget’s disease of bone in men
and women.

Risofos Dosage
➢Treatment of Postmenopausal Osteoporosis: The
recommended dosage is: one 5 mg tablet orally,
taken daily or one 35 mg tablet orally, taken once
a week or one 75 mg tablet orally, taken on
two consecutive days for a total of two tablets each
month or one 150 mg tablet orally, taken once a
month.
The dosage of Risofos tablets (Risedronate Sodium
tablets) should be taken at least 30 minutes before
the first food or drink of the day other than water.
Risofos must be swallowed while the patient is in an
upright position and with a full glass of plain water.
Patients should not lie down for 30 minutes after
taking the medication. The dosage is given below:

Risofos Tablets Dosage
➢Treatment to Increase Bone Mass in
Men with Osteoporosis: The
recommended dosage is: one 35 mg
tablet orally, taken once a week.
➢ Treatment and Prevention of
Glucocorticoid-Induced Osteoporosis: The
recommended dosage is: one 5 mg tablet
orally, taken daily
The dosage of Risofos tablets (Risedronate
Sodium tablets) is given below:

Generic Risedronate Sodium Dosage
➢Treatment of Paget’s Disease: The
recommended dosage is is 30 mg orally
once daily for 2 months. Re-treatment may
be considered (following post-treatment
observation of at least 2 months) in case
relapse occurs, or if treatment fails to
normalize serum alkaline phosphatase. For
re-treatment, the dose and duration of
therapy are the same as for initial treatment.
No data are available on more than 1 course
of re-treatment.
The dosage of Risofos tablets (Risedronate
Sodium tablets) is given below:

Storage Instructions
Risofos (Generic Risedronate Sodium
tablets) have to be stored at controlled
room temperature i.e. from 20°C to 25°C
(68°F to 77°F) with excursions permitted
between 15° to 30°C (59° to 86°F).
Keep this as well as all other medicines
away from children and pets.

Risofos Tablets Warnings
Upper gastrointestinal irritation may occur.
Dosing instructions should be followed.
Discontinue use if new or worsening
symptoms occur.
Hypocalcemia may worsen and must be
corrected prior to use.
Osteonecrosis of the jaw has been reported
rarely.
Severe bone, joint, or muscle pain may occur.
Consider discontinuing use if severe
symptoms develop.

Risofos Tablets Warnings
Severe bone, joint, or muscle pain may
occur. Consider discontinuing use if severe
symptoms develop.
Before starting treatment in patients with
glucocorticoid-induced osteoporosis, sex
steroid hormonal status of both men and
women should be ascertained and
appropriate replacement considered.
Bisphosphonates may interfere with bone-
imaging agents.

Risofos Tablets
Contraindications
Risofos tablets are contraindicated in
patients with a hypersensitivity to
Risedronate Sodium or any other
component of this medication.
Other contraindications include inability to
stand or sit upright for at least 30 minutes
and Hypocalcemia.

Risofos Side Effects
➢Most common adverse reactions reported
in more than 10% of patients treated with
Risedronate Sodium tablets (Risofos) and
with a higher frequency than placebo are:
back pain, arthralgia, abdominal pain, and
dyspepsia.
➢Hypersensitivity reactions (angioedema ,
generalized rash, bullous skin reactions), and
eye inflammation (iritis, uveitis) have been
reported rarely.

Risedronate Sodium Overdose
Decreases in serum calcium and
phosphorus following substantial overdose
could be expected in some patients.
Signs and symptoms of hypocalcemia can
also occur in some of these patients.
Milk or antacids containing calcium must
be given to bind Risedronate Sodium
(Risofos tablets) and reduce absorption of
the medicine.

Risofos Overdose
In cases of substantial overdose, gastric
lavage may be considered to remove
unabsorbed medicine.
Standard procedures that are effective for
treating hypocalcemia, including the
administration of calcium intravenously,
would be expected to restore physiologic
amounts of ionized calcium and to relieve
signs and symptoms of hypocalcemia.

Risedronate Sodium During Pregnancy
Risedronate Sodium tablets (Risofos) has
been classified by the US FDA as
Pregnancy Category C.
There are no adequate and well-controlled
studies of Risedronate tablets (Risofos) in
pregnant women.
Risofos should be used during pregnancy
only if the potential benefit justifies the
potential risk to the mother and fetus.

Risofos Tablets
For more details on
Risofos Tablets click here
Risofos (Risedronate Sodium tablets) by
Cipla Limited, India.

Risofos (Generic Risedronate Sodium Tablets)

Recommended

Recommended

More Related Content

Similar to Risofos (Generic Risedronate Sodium Tablets)

Similar to Risofos (Generic Risedronate Sodium Tablets) (20)

More from Clearsky Pharmacy

More from Clearsky Pharmacy (20)

Recently uploaded

Recently uploaded (20)

Risofos (Generic Risedronate Sodium Tablets)