Moxif (Generic Moxifloxacin Hydrochloride Tablets) 400 mg film-coated tablets are used for the treatment of different types of bacterial infections of the skin, sinuses, lungs, or stomach. This medicine is also used to treat and prevent plague. Fluoroquinolone antibiotics could cause serious or disabling side effects. Moxif should be used only for infections that cannot be treated with a safer antibiotic. It is used to treat community acquired pneumonia, plague, bacterial sinusitis, and chronic bronchitis with bacterial infection. Moxifloxacin should be used only when it is considered inappropriate to use antibacterial agents that are commonly recommended for the initial treatment of these infections or when these have failed: Acute bacterial sinusitis (adequately diagnosed), Acute exacerbations of chronic bronchitis (adequately diagnosed), Community acquired pneumonia, except severe cases, Mild to moderate pelvic inflammatory disease (i.e. infections of female upper genital tract, including salpingitis and endometritis), without an associated tubo-ovarian or pelvic abscess.

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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)

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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Moxif (Generic Moxifloxacin Hydrochloride Tablets) 400 mg film-coated tablets
are used for the treatment of different types of bacterial infections of the skin,
sinuses, lungs, or stomach. This medicine is also used to treat and prevent plague.
Fluoroquinolone antibiotics could cause serious or disabling side effects.
Moxif should be used only for infections that cannot be treated with a safer
antibiotic. It is used to treat community acquired pneumonia, plague, bacterial
sinusitis, and chronic bronchitis with bacterial infection.
Moxifloxacin should be used only when it is considered inappropriate to use
antibacterial agents that are commonly recommended for the initial treatment of
these infections or when these have failed: Acute bacterial sinusitis (adequately
diagnosed), Acute exacerbations of chronic bronchitis (adequately diagnosed),
Community acquired pneumonia, except severe cases, Mild to moderate pelvic
inflammatory disease (i.e. infections of female upper genital tract, including
salpingitis and endometritis), without an associated tubo-ovarian or pelvic abscess.

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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Active Ingredient
The active ingredient present in Moxif tablets
is Moxifloxacin Hydrochloride.
Each film coated tablet of Moxif contains
Moxifloxacin Hydrochloride equivalent to 400
mg of Moxifloxacin.

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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Chemical Structure
The structure of Moxifloxacin Hydrochloride is given below:

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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Moxif Tablets are manufactured by Torrent Pharmaceuticals
Limited, India in the strength of 400 mg.
(Website: https://www.torrentpharma.com/ )
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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Moxifloxacin Hydrochloride Tablets – Brand Names
Moxifloxacin Hydrochloride tablets are
available under various drug trade names
that include Avelox, Moxif, MXF-400, M-
Cin, Moxicip, Moxiflox, Mxigram,
Sitromox-400 and Staxom.

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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Uses of Moxif Tablets
Moxif (Generic Moxifloxacin Hydrochloride Tablets) is used to treat
bacterial infections in many different parts of the body. It is also used to
treat and prevent plague (including pneumonic and septicemic plague).
Moxifloxacin belongs to the class of medicines known as quinolone
antibiotics. It works by killing bacteria or preventing their growth.
However, this medicine will not work for colds, flu, or other virus
infections.
To reduce the development of drug-resistant bacteria and maintain the
effectiveness of Moxif and other antibacterial drugs. Moxif should be
used only to treat or prevent infections that are proven or strongly
suspected to be caused by susceptible bacteria.
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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Moxif Tablets Dosage
The recommended adult dosage is administered orally once a day. No
dosage adjustment in patients with renal or hepatic impairment.
The adult dosage of Moxif tablets Generic Moxifloxacin
Hydrochloride Tablets) is given below:
Community Acquired Pneumonia: 400 mg once every 24 hours for 7 to
14 days
Uncomplicated Skin and Skin Structure Infections (SSSI): 400 mg once
every 24 hours for 7 days
Complicated SSSI: 400 mg once every 24 hours for 7 to 21 days
Complicated Intra-Abdominal Infections: 400 mg once every 24 hours for
5 to 14 days
Plague: 400 mg for 10 to 14 days
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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Moxif Tablets Dosage
The adult dosage of Moxif tablets Generic Moxifloxacin
Hydrochloride Tablets) is given below:
Acute Bacterial Sinusitis: 400 mg once every 24 hours for 10 days
Acute Bacterial Exacerbation of Chronic Bronchitis: 400 mg once every
24 hours for 5 days
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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Contraindications
Moxif is contraindicated in patients with a hypersensitivity to
Moxifloxacin Hydrochloride, other Quinolones or any other
component of this medication.
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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Storage Instructions
Moxif Tablets (Generic Moxifloxacin
Hydrochloride Tablets) have to be stored at
controlled room temperature i.e. from 20°C to
25°C (68°F to 77°F) with excursions
permitted between 15° to 30°C (59° to 86°F).
Keep this as well as all other medicines away
from children and pets.
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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Warnings
Prolongation of the QT interval and isolated cases of torsade de
pointes has been observed. Avoid use of Moxif (Moxifloxacin
Hydrochloride Tablets) in patients with known prolongation,
proarrhythmic conditions such as clinically significant bradycardia or
acute myocardial ischemia, hypokalemia, hypomagnesemia, and
with drugs that prolong the QT interval.
Hypersensitivity and other serious reactions: Serious and sometimes
fatal reactions, including anaphylactic reactions, could occur after
first or subsequent doses of Moxifloxacin Hydrochloride tablets.
Discontinue Moxifloxacin Hydrochloride tablets at first sign of skin
rash, jaundice or any other sign of hypersensitivity.
Clostridium difficile-Associated Diarrhea: Evaluate if diarrhea occurs.

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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Side Effects
Most common Moxifloxacin Hydrochloride (Moxif
tablets) side effects with an incidence rate of 3% or
greater were nausea, diarrhea, headache, and dizziness.
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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Overdose
Single oral overdoses up to 2.8 gms of Moxifloxacin Hydrochloride
Tablets were not associated with any serious adverse events. In the event
of acute overdose, evacuate the stomach and maintain adequate
hydration. Monitor ECG due to the possibility of QT interval prolongation.
Carefully observe the patient and give supportive treatment. The
administration of activated charcoal as soon as possible after oral
overdose could prevent excessive increase of systemic moxifloxacin
exposure. About 3% and 9% of the dose of Moxifloxacin, as well as about
2% and 4.5% of its glucuronide metabolite are removed by continuous
ambulatory peritoneal dialysis and hemodialysis, respectively.
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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
Moxif Tablets During Pregnancy
Moxifloxacin Hydrochloride (Moxif tablets) has been classified
by the US FDA as Pregnancy Category C.
Since no adequate or well-controlled studies have been conducted in
pregnant women, Moxifloxacin Hydrochloride (Moxif tablets) should
be used during pregnancy only if the potential benefit justifies the
potential risk to the fetus.
Moxifloxacin was not teratogenic when administered to pregnant rats
during organogenesis at oral doses as high as 500 mg/kg/day, but
decreased fetal body weights and slightly delayed fetal skeletal
development (indicative of fetotoxicity) were observed.
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Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets)
For more details on
Moxif Tablets click here
Moxif Tablets (Generic Moxifloxacin Hydrochloride Tablets) by
Torrent Pharmaceuticals Limited, India.
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