How do neutrophils find and get to an infection? Solution Neutrophils nucleus has a complex, lobulated shape. In a cross-section, neutrophils look like they have more than one nucleus. Neutrophils have this unique nuclear shape, it makes these cells very easy to identify under the microscope. They are very abundant, making up about 60% of the immune cells in our blood. They are formed from stem cells in the bone marrow. Neutrophils derives from staining characteristics on hematoxylin and eosin (H&E) histological or cytological preparations. Neutrophils are the first cells to migrate to a site of infection, and with the help of other innate immune cells, they work hard to keep things under control until the powerful adaptive immune system kicks..