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Ques-7:
Chemokine receptor type 5 is main receptor occupied by macrophage-tropic HIV to attach to a
new immune cell. Cluster differentiation 4 (CD4) are the primary cell surface receptor for HIV.
CD4 cell surface is the docking area for HIV. Delta 32-mutation of CCR5 provide resistance to
diseases caused by very different organisms such as HIV and bubonic plague because muatated
CCR5 is going to produce a smaller receptor protein out side of the immne cells result in
inability of “HIV or Bactrium Yersinia pestis that cause bubonic plague” to bind to CCR5 co-
receptor protein. Thereby, there will be no chance of getting infection of these pathogens
Ques-8: Steve crohn is nephew of Bernard Crohn who has named after Crohn’s disease. He is
first person who had capability to prevent HIV infection because he had delta-32 mutated CCR5
on his white blood cells that resist HIV infection (thats why researchers interested in studying his
genome).
Solution
Ques-7:
Chemokine receptor type 5 is main receptor occupied by macrophage-tropic HIV to attach to a
new immune cell. Cluster differentiation 4 (CD4) are the primary cell surface receptor for HIV.
CD4 cell surface is the docking area for HIV. Delta 32-mutation of CCR5 provide resistance to
diseases caused by very different organisms such as HIV and bubonic plague because muatated
CCR5 is going to produce a smaller receptor protein out side of the immne cells result in
inability of “HIV or Bactrium Yersinia pestis that cause bubonic plague” to bind to CCR5 co-
receptor protein. Thereby, there will be no chance of getting infection of these pathogens
Ques-8: Steve crohn is nephew of Bernard Crohn who has named after Crohn’s disease. He is
first person who had capability to prevent HIV infection because he had delta-32 mutated CCR5
on his white blood cells that resist HIV infection (thats why researchers interested in studying his
genome).

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Ques-7Chemokine receptor type 5 is main receptor occupied by macr.pdf

  • 1. Ques-7: Chemokine receptor type 5 is main receptor occupied by macrophage-tropic HIV to attach to a new immune cell. Cluster differentiation 4 (CD4) are the primary cell surface receptor for HIV. CD4 cell surface is the docking area for HIV. Delta 32-mutation of CCR5 provide resistance to diseases caused by very different organisms such as HIV and bubonic plague because muatated CCR5 is going to produce a smaller receptor protein out side of the immne cells result in inability of “HIV or Bactrium Yersinia pestis that cause bubonic plague” to bind to CCR5 co- receptor protein. Thereby, there will be no chance of getting infection of these pathogens Ques-8: Steve crohn is nephew of Bernard Crohn who has named after Crohn’s disease. He is first person who had capability to prevent HIV infection because he had delta-32 mutated CCR5 on his white blood cells that resist HIV infection (thats why researchers interested in studying his genome). Solution Ques-7: Chemokine receptor type 5 is main receptor occupied by macrophage-tropic HIV to attach to a new immune cell. Cluster differentiation 4 (CD4) are the primary cell surface receptor for HIV. CD4 cell surface is the docking area for HIV. Delta 32-mutation of CCR5 provide resistance to diseases caused by very different organisms such as HIV and bubonic plague because muatated CCR5 is going to produce a smaller receptor protein out side of the immne cells result in inability of “HIV or Bactrium Yersinia pestis that cause bubonic plague” to bind to CCR5 co- receptor protein. Thereby, there will be no chance of getting infection of these pathogens Ques-8: Steve crohn is nephew of Bernard Crohn who has named after Crohn’s disease. He is first person who had capability to prevent HIV infection because he had delta-32 mutated CCR5 on his white blood cells that resist HIV infection (thats why researchers interested in studying his genome).