Ques-7: Chemokine receptor type 5 is main receptor occupied by macrophage-tropic HIV to attach to a new immune cell. Cluster differentiation 4 (CD4) are the primary cell surface receptor for HIV. CD4 cell surface is the docking area for HIV. Delta 32-mutation of CCR5 provide resistance to diseases caused by very different organisms such as HIV and bubonic plague because muatated CCR5 is going to produce a smaller receptor protein out side of the immne cells result in inability of “HIV or Bactrium Yersinia pestis that cause bubonic plague” to bind to CCR5 co- receptor protein. Thereby, there will be no chance of getting infection of these pathogens Ques-8: Steve crohn is nephew of Bernard Crohn who has named after Crohn’s disease. He is first person who had capability to prevent HIV infection because he had delta-32 mutated CCR5 on his white blood cells that resist HIV infection (thats why researchers interested in studying his genome). Solution Ques-7: Chemokine receptor type 5 is main receptor occupied by macrophage-tropic HIV to attach to a new immune cell. Cluster differentiation 4 (CD4) are the primary cell surface receptor for HIV. CD4 cell surface is the docking area for HIV. Delta 32-mutation of CCR5 provide resistance to diseases caused by very different organisms such as HIV and bubonic plague because muatated CCR5 is going to produce a smaller receptor protein out side of the immne cells result in inability of “HIV or Bactrium Yersinia pestis that cause bubonic plague” to bind to CCR5 co- receptor protein. Thereby, there will be no chance of getting infection of these pathogens Ques-8: Steve crohn is nephew of Bernard Crohn who has named after Crohn’s disease. He is first person who had capability to prevent HIV infection because he had delta-32 mutated CCR5 on his white blood cells that resist HIV infection (thats why researchers interested in studying his genome)..