The DNA matching is carried out by comparing the DNA sequences of the STR loci in these samples. STR analysis is one of the major tools employed in forensic sciences. STR regions are highly polymorphic in nature. STR analysis uses this advantage to distinguish one DNA sample from another. STR is basically a stretch of DNA (2-13 nucleotides) that is repeated hundreds of times. This basic repeats differ from one individual to another. Or related individuals may contain similar repeats compared to unrelated individuals. They use specific primers to amplify the sequences through PCR and then visualize through electrophoresis. But ultimately by comparing STR loci, one can discrimate between unrelated individuals. Solution The DNA matching is carried out by comparing the DNA sequences of the STR loci in these samples. STR analysis is one of the major tools employed in forensic sciences. STR regions are highly polymorphic in nature. STR analysis uses this advantage to distinguish one DNA sample from another. STR is basically a stretch of DNA (2-13 nucleotides) that is repeated hundreds of times. This basic repeats differ from one individual to another. Or related individuals may contain similar repeats compared to unrelated individuals. They use specific primers to amplify the sequences through PCR and then visualize through electrophoresis. But ultimately by comparing STR loci, one can discrimate between unrelated individuals..