Q41 Which statement below about DNA is FALSE DNA is prese.pdf

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Q4.1. Which statement below about DNA is FALSE? DNA is present in and essential for all living cells. DNA is located in the nucleus of eukaryotic cells. DNA is not always perfectly copied during DNA replication. All DNA molecules in human cells are circular. Q4.2. In the diagram below showing halves of four DNA replication bubbles, RNA primers are shown as red and DNA is shown as black. Which bubble's 5 and 3 ' labels are correct? Q4.3. What would be the consequence if a cell were unable to replicate its DNA? The cell would not be able to undergo cell division as it normally would. The cell would be unable to make proteins based on the information in DNA. The cell would not form a nucleus, because the nucleus contains DNA. The cell would become a cancer cell, dividing in an uncontrolled manner..

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What phase of chemical respiration generates more ATP? The aerobic phase. The anaerobic phase. The mitochondrial phase. None of these. QUESTION 2 Which is NOT a difference between DNA and RNA? DNA has deoxyribose in its sugar-phosphate backbone, but RNA has ribose. DNA has monomers made of nucleotides, but RNA has monomers made of ATP. DNA uses the base thymine, while RNA uses uracil. None of these. QUESTION 3 What is complementary base pairing in the DNA molecule or when RNA interacts with DNA? C always pairs with G , and T always pairs with A (or U in RNA). DNA always binds to RNA, and RNA always binds to DNA. Phosphate groups binding to ribose sugars. Nitrogen-containing bases binding to ribose sugars. QUESTION 4 What is the "Central Dogma of Biology," and how can it be expressed more accurately? Protein to DNA to RNA; Protein - transcription - DNA - translation -RNA DNA to Protein to RNA; DNA - translation - Protein - transcription - RNA Protein to RNA to DNA; Protein - transcription - RNA - translation - DNA DNA to RNA to Protein; DNA - transcription - RNA - translation - Protein What are the 3 types of RNA that are involved in the synthesis of proteins from the DNA genetic code. Inverted, Compressed, Depolymerized Messenger, Ribosomal, Transfer Gluco-, Proteo, Nucleo- None of these. QUESTION 6 What are the two types of cell division, and how are they different? Chromatin and prohase, chromatin covers the DNA, and in prophase it disappears. Anaphase and Telophase, in anaphase the chromosomes pull apart, and in telophase, the nucleus re-forms. The cell cycle and cell death, in the cell cycle, the cell lives and grows, and at the end of it, there is cell death. Mitosis and Meiosis. In mitosis, each cell resulting from one divison has exactly the same DNA as the orginal cell that divided, but in meiosis, there are two divisions, and the four cellls which result have only half the number of chromosomes as the orignai cell. QUESTION 7 What are stem cells? Cells which belong to the stalk of a plant, between the roots and the leaves. Cells that are not found in animals. Cells which are capable of changing (differentiating) into more than one other cell type. None of these. QUESTION 8 What are the four major types of tissues? Brain, Heart, Lung, Stomach Epithelial, Connective, Nervous, Muscle Skin, Hair, Blood, Saliva None of these. Which is a NOT a characteristic of epithelial tissue? It conducts electrical impulses. It is avascular. it forms glands. All of these are characteristics of epithelial tissue. QUESTION 10 Unlike in epithelial tissue, in connective tissue: The cells don't have a nucleus. The cells are spaced apart. Most of the cells are non-living. None of these..

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1.) What does “exonuclease” activity mean? Which enzyme important for DNA polymerization has both 5’ – 3’ AND 3’ – 5’ exonuclease activity? Which is important for proofreading function? 2.) How are the site(s) where replication begin(s) is/are characterized as in both prokaryotes and eukaryotes? What is beneficial about this? Are the sites the same in prokaryotes and eukaryotes? 3.) Arrange the following proteins in the proper order in which they participate in DNA replication. 1 = Primase 2 = Helicase 3 = Single-strand binding proteins 4 = DNA polymerase I 5 =DNA polymerase III 4.) When does DNA replicate in the cell cycle of eukaryotes and prokaryotes? 5.) Why are Okazaki fragments only found on the lagging strand, but not on the leading strand of DNA? 6.) What protein transports the histones of Nucleosomes into the nucleus? 7.) Describe the differences between Topoisomerase I and Topoisomerase II. 8.) During DNA replication, ___________ adds an RNA primer to naked template strands of DNA. Why is this necessary during replication? What fills the gap after removal of this RNA primer? 9.) What is the problem with the ends of linear eukaryotic chromosomes? How does telomerase help the issue? Solution 1. Exonuclease activity means that enzymes work by cleaving nucleotides one at a time from the end (exo) of a polynucleotide chain. A hydrolyzing reaction breaks phosphodiester bonds at either the 3’ or the 5’ ends. DNA polymerase I is the enzyme important for DNA polymerization and has both 5’ – 3’ and 3’ – 5’ exonuclease activity, which is used in editing and proofreading DNA for errors. The 3\' to 5\' can remove only one mononucleotide at a time, whereas the 5\' to 3\' activity can remove up to 10 nucleotides at a time. 2. Sites from which the process of replication starts are different in prokaryotes and Eukaryotes. Prokaryotes have only one origin of replication per DNA molecule, whereas in ekaryotes, there are multiple sites for origin of replication. To initiate DNA replication in Eukaryotes, multiple replicative proteins assemble on and dissociate from these replicative origins. DNA double helix is unwound and an initial priming event by DNA polymerase occurs on the leading strand.To initiate the process of DNA replication, multiple replicative proteins assemble on and dissociate from these replicative origins. The individual factors work together to direct the formation of the pre-replication complex (pre-RC), a key intermediate in the replication initiation process. In case of prokaryotes, Helicase separates the DNA to form a replication fork at the origin of replication where DNA replication begins. Replication forks extend bi-directionally as replication continues. The initiation of DNA replication is mediated by DnaA, a protein that binds to a region of the origin known as the DnaA box. E. coli, has 4 DnaA boxes, each of which contains a highly conserved 9 bp consensus sequence 5\' - TTATCCACA - 3\'. 3. Enzymes that participate in DNa.

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Q41 Which statement below about DNA is FALSE DNA is prese.pdf

1. Q4.1. Which statement below about DNA is FALSE? DNA is present in and essential for all living cells. DNA is located in the nucleus of eukaryotic cells. DNA is not always perfectly copied during DNA replication. All DNA molecules in human cells are circular. Q4.2. In the diagram below showing halves of four DNA replication bubbles, RNA primers are shown as red and DNA is shown as black. Which bubble's 5 and 3 ' labels are correct? Q4.3. What would be the consequence if a cell were unable to replicate its DNA? The cell would not be able to undergo cell division as it normally would. The cell would be unable to make proteins based on the information in DNA. The cell would not form a nucleus, because the nucleus contains DNA. The cell would become a cancer cell, dividing in an uncontrolled manner.

Q41 Which statement below about DNA is FALSE DNA is prese.pdf

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