Laboratory Biosecurity

1. LABORATORY
BIOSECURITY
By Dr. Abdoalati Alswehli
MSc Human Anatomy
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2. INTRODUCTION
 Today, the nation is facing a new challenge
in safeguarding the public health from
potential domestic or international terrorism
involving the use of dangerous biological
agents or toxins.
 So, increased security within the
microbiological and biomedical community
in order to protect biological pathogens and
toxins from theft, loss, or misuse is
mandatory. 2

3. DEFINITION
Laboratory biosecurity, is protection,
control and accountability for valuable
biologic material (VBM) in order to
prevent their unauthorized access,
loss, theft, misuse, diversion, or
intentional release.
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4.  So, biosecurity is protecting agents from bad
people.
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5.  Limit access to areas that contain certain biological
agents or assets.
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6. WHAT VALUABLE BIOLOGIC MATERIAL
(VBM) IS ?
 Collections and references strains ( cell culture
lines ).
 Pathogens and toxins .. Should address the dual-
use nature.
 Vaccines and other pharmaceutical products.
 Yeast and bacteria related to development and
production of food products.
 Genetically modified organism(GOM).
 Non-pathogenic microorganism
 Cellular components and genetic elements ( DNA
and /or RNA). 6

7. WHY WE HAVE TO THINK ABOUT
BIOSECURITY ?
 Because those dangerous agent can be :
 Dual-use research of concern (DURC)
means can be use either for good or bad purposes.
 Bio-warfare/terrorist
biological weapons and Anthrax.
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8. CATEGORIES OF BIOTERRORISM AGENTS
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9. PRINCIPLES OF BIOSECURITY
1. restricted information.
2. Restricted communication.
3. Coding of samples in storage.
4. Close barrier in case of
emergency .
5. Tackle the gap between sender
and receiver .
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10. COMPONENTS OF LAB-BIOSECURITY
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11. Physical security
We want to keep agents inside
the lab and to prevent them from
someone who had bad intention to
steal it.
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12. PHYSICAL PROTECTION
 Physical security and accesses control, Concentric
 Layers of protection :
 Property protection areas (1)
Low risk assets
( ground, public access offices )
 Limited area (2)
Moderate risk assets e.g. laboratories
 Exclusion areas (3)
High risk assets .
e.g. high containment lab, biological agents/toxins.
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2
3
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13.  Personnel security
is the management of staff to assist in the
protection people, information and assets.
 The purpose of personnel security is to provide a
level of assurance.
 Personnel security aims to:
 reduce the risk of loss or damage.
 minimise potential for misuse.
 support a culture of protective security.
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14. MATERIAL USE AND ACCOUNTABILITY
 Material accountability is essential part of good
laboratory practice.
 Material accountability requires that you know:
 What material you have.
 Who is responsible for it.
 Where it is located
 Who has access to it .
 How it’s controlled
and documented.
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15.  Transfer security
The agents which already in lab should be monitoring
where it goes, what u did with those agents is under
the biosecurity, even when destroy , you have to have
document saying that these agents already been
destroyed .
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16.  Information security
Information which come up from agents
have to share these information at least in the
institute.
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17. REFERENCES
 Biosafety and biosecurity lecture by Dr. Dewajani
purnomosari
 PPT slides Dr. Subhash J. Bhore
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18. Thanks!
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